{"id":"https://openalex.org/W2969288366","doi":"https://doi.org/10.1016/j.biochi.2019.08.010","title":"Antithrombin is incorporated into exosomes produced by antithrombin non-expressing cells","display_name":"Antithrombin is incorporated into exosomes produced by antithrombin non-expressing cells","publication_year":2019,"publication_date":"2019-08-21","ids":{"openalex":"https://openalex.org/W2969288366","doi":"https://doi.org/10.1016/j.biochi.2019.08.010","mag":"2969288366","pmid":"https://pubmed.ncbi.nlm.nih.gov/31445073"},"language":"en","primary_location":{"id":"doi:10.1016/j.biochi.2019.08.010","doi":"https://doi.org/10.1016/j.biochi.2019.08.010","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.biochi.2019.08.010","pdf_url":null,"source":{"id":"https://openalex.org/S75247133","display_name":"Biochimie","issn_l":"0037-9042","issn":["0037-9042","0300-9084","1638-6183"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimie","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035370625","display_name":"Gin\u00e9s Luengo\u2010Gil","orcid":"https://orcid.org/0000-0001-9940-0415","observed_orcids":["https://orcid.org/0000-0001-9940-0415"]},"institutions":[{"id":"https://openalex.org/I4210091031","display_name":"Hospital General Universitario Morales Meseguer","ror":"https://ror.org/00cfm3y81","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210091031"]},{"id":"https://openalex.org/I4210115362","display_name":"Centro Regional de Hemodonaci\u00f3n","ror":"https://ror.org/02a57s352","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210115362"]},{"id":"https://openalex.org/I4210146619","display_name":"Instituto Murciano de Investigaci\u00f3n Biosanitaria","ror":"https://ror.org/053j10c72","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210146619"]},{"id":"https://openalex.org/I80180929","display_name":"Universidad de Murcia","ror":"https://ror.org/03p3aeb86","country_code":"ES","type":"education","lineage":["https://openalex.org/I80180929"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Gin\u00e9s Luengo-Gil","raw_affiliation_strings":["Servicio de Hematolog\u00eda y Oncolog\u00eda M\u00e9dica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonaci\u00f3n, Universidad de Murcia, IMIB-Arrixaca, U-765, Center for Biomedical Research on Rare Diseases, Murcia, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicio de Hematolog\u00eda y Oncolog\u00eda M\u00e9dica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonaci\u00f3n, Universidad de Murcia, IMIB-Arrixaca, U-765, Center for Biomedical Research on Rare Diseases, Murcia, Spain","institution_ids":["https://openalex.org/I4210091031","https://openalex.org/I4210115362","https://openalex.org/I4210146619","https://openalex.org/I80180929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068657309","display_name":"Antonio Bernardino Garc\u00eda-Andreo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091031","display_name":"Hospital General Universitario Morales Meseguer","ror":"https://ror.org/00cfm3y81","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210091031"]},{"id":"https://openalex.org/I4210115362","display_name":"Centro Regional de Hemodonaci\u00f3n","ror":"https://ror.org/02a57s352","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210115362"]},{"id":"https://openalex.org/I4210146619","display_name":"Instituto Murciano de Investigaci\u00f3n Biosanitaria","ror":"https://ror.org/053j10c72","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210146619"]},{"id":"https://openalex.org/I80180929","display_name":"Universidad de Murcia","ror":"https://ror.org/03p3aeb86","country_code":"ES","type":"education","lineage":["https://openalex.org/I80180929"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Antonio Bernardino Garc\u00eda-Andreo","raw_affiliation_strings":["Servicio de Hematolog\u00eda y Oncolog\u00eda M\u00e9dica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonaci\u00f3n, Universidad de Murcia, IMIB-Arrixaca, U-765, Center for Biomedical Research on Rare Diseases, Murcia, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicio de Hematolog\u00eda y Oncolog\u00eda M\u00e9dica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonaci\u00f3n, Universidad de Murcia, IMIB-Arrixaca, U-765, Center for Biomedical Research on Rare Diseases, Murcia, Spain","institution_ids":["https://openalex.org/I4210091031","https://openalex.org/I4210115362","https://openalex.org/I4210146619","https://openalex.org/I80180929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045896019","display_name":"Carmen Ortega-Sabater","orcid":"https://orcid.org/0000-0002-5469-1009","observed_orcids":["https://orcid.org/0000-0002-5469-1009"]},"institutions":[{"id":"https://openalex.org/I4210091031","display_name":"Hospital General Universitario Morales Meseguer","ror":"https://ror.org/00cfm3y81","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210091031"]},{"id":"https://openalex.org/I4210115362","display_name":"Centro Regional de Hemodonaci\u00f3n","ror":"https://ror.org/02a57s352","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210115362"]},{"id":"https://openalex.org/I4210146619","display_name":"Instituto Murciano de Investigaci\u00f3n Biosanitaria","ror":"https://ror.org/053j10c72","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210146619"]},{"id":"https://openalex.org/I80180929","display_name":"Universidad de Murcia","ror":"https://ror.org/03p3aeb86","country_code":"ES","type":"education","lineage":["https://openalex.org/I80180929"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Carmen Ortega-Sabater","raw_affiliation_strings":["Servicio de Hematolog\u00eda y Oncolog\u00eda M\u00e9dica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonaci\u00f3n, Universidad de Murcia, IMIB-Arrixaca, U-765, Center for Biomedical Research on Rare Diseases, Murcia, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicio de Hematolog\u00eda y Oncolog\u00eda M\u00e9dica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonaci\u00f3n, Universidad de Murcia, IMIB-Arrixaca, U-765, Center for Biomedical Research on Rare Diseases, Murcia, Spain","institution_ids":["https://openalex.org/I4210091031","https://openalex.org/I4210115362","https://openalex.org/I4210146619","https://openalex.org/I80180929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069389286","display_name":"Nataliya Bohdan","orcid":"https://orcid.org/0000-0002-2969-2843","observed_orcids":["https://orcid.org/0000-0002-2969-2843"]},"institutions":[{"id":"https://openalex.org/I4210091031","display_name":"Hospital General Universitario Morales Meseguer","ror":"https://ror.org/00cfm3y81","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210091031"]},{"id":"https://openalex.org/I4210115362","display_name":"Centro Regional de Hemodonaci\u00f3n","ror":"https://ror.org/02a57s352","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210115362"]},{"id":"https://openalex.org/I4210146619","display_name":"Instituto Murciano de Investigaci\u00f3n Biosanitaria","ror":"https://ror.org/053j10c72","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210146619"]},{"id":"https://openalex.org/I80180929","display_name":"Universidad de Murcia","ror":"https://ror.org/03p3aeb86","country_code":"ES","type":"education","lineage":["https://openalex.org/I80180929"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Nataliya Bohdan","raw_affiliation_strings":["Servicio de Hematolog\u00eda y Oncolog\u00eda M\u00e9dica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonaci\u00f3n, Universidad de Murcia, IMIB-Arrixaca, U-765, Center for Biomedical Research on Rare Diseases, Murcia, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicio de Hematolog\u00eda y Oncolog\u00eda M\u00e9dica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonaci\u00f3n, Universidad de Murcia, IMIB-Arrixaca, U-765, Center for Biomedical Research on Rare Diseases, Murcia, Spain","institution_ids":["https://openalex.org/I4210091031","https://openalex.org/I4210115362","https://openalex.org/I4210146619","https://openalex.org/I80180929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012390069","display_name":"Salvador Esp\u00edn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091031","display_name":"Hospital General Universitario Morales Meseguer","ror":"https://ror.org/00cfm3y81","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210091031"]},{"id":"https://openalex.org/I4210115362","display_name":"Centro Regional de Hemodonaci\u00f3n","ror":"https://ror.org/02a57s352","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210115362"]},{"id":"https://openalex.org/I4210146619","display_name":"Instituto Murciano de Investigaci\u00f3n Biosanitaria","ror":"https://ror.org/053j10c72","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210146619"]},{"id":"https://openalex.org/I80180929","display_name":"Universidad de Murcia","ror":"https://ror.org/03p3aeb86","country_code":"ES","type":"education","lineage":["https://openalex.org/I80180929"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Salvador Esp\u00edn","raw_affiliation_strings":["Servicio de Hematolog\u00eda y Oncolog\u00eda M\u00e9dica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonaci\u00f3n, Universidad de Murcia, IMIB-Arrixaca, U-765, Center for Biomedical Research on Rare Diseases, Murcia, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicio de Hematolog\u00eda y Oncolog\u00eda M\u00e9dica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonaci\u00f3n, Universidad de Murcia, IMIB-Arrixaca, U-765, Center for Biomedical Research on Rare Diseases, Murcia, Spain","institution_ids":["https://openalex.org/I4210091031","https://openalex.org/I4210115362","https://openalex.org/I4210146619","https://openalex.org/I80180929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091802539","display_name":"Julia Pe\u00f1as-Mart\u00ednez","orcid":"https://orcid.org/0000-0001-8964-0909","observed_orcids":["https://orcid.org/0000-0001-8964-0909"]},"institutions":[{"id":"https://openalex.org/I4210091031","display_name":"Hospital General Universitario Morales Meseguer","ror":"https://ror.org/00cfm3y81","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210091031"]},{"id":"https://openalex.org/I4210115362","display_name":"Centro Regional de Hemodonaci\u00f3n","ror":"https://ror.org/02a57s352","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210115362"]},{"id":"https://openalex.org/I4210146619","display_name":"Instituto Murciano de Investigaci\u00f3n Biosanitaria","ror":"https://ror.org/053j10c72","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210146619"]},{"id":"https://openalex.org/I80180929","display_name":"Universidad de Murcia","ror":"https://ror.org/03p3aeb86","country_code":"ES","type":"education","lineage":["https://openalex.org/I80180929"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Julia Pe\u00f1as-Mart\u00ednez","raw_affiliation_strings":["Servicio de Hematolog\u00eda y Oncolog\u00eda M\u00e9dica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonaci\u00f3n, Universidad de Murcia, IMIB-Arrixaca, U-765, Center for Biomedical Research on Rare Diseases, Murcia, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicio de Hematolog\u00eda y Oncolog\u00eda M\u00e9dica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonaci\u00f3n, Universidad de Murcia, IMIB-Arrixaca, U-765, Center for Biomedical Research on Rare Diseases, Murcia, Spain","institution_ids":["https://openalex.org/I4210091031","https://openalex.org/I4210115362","https://openalex.org/I4210146619","https://openalex.org/I80180929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005897512","display_name":"Elena Mart\u00ednez-Planes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091031","display_name":"Hospital General Universitario Morales Meseguer","ror":"https://ror.org/00cfm3y81","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210091031"]},{"id":"https://openalex.org/I4210115362","display_name":"Centro Regional de Hemodonaci\u00f3n","ror":"https://ror.org/02a57s352","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210115362"]},{"id":"https://openalex.org/I4210146619","display_name":"Instituto Murciano de Investigaci\u00f3n Biosanitaria","ror":"https://ror.org/053j10c72","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210146619"]},{"id":"https://openalex.org/I80180929","display_name":"Universidad de Murcia","ror":"https://ror.org/03p3aeb86","country_code":"ES","type":"education","lineage":["https://openalex.org/I80180929"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Elena Mart\u00ednez-Planes","raw_affiliation_strings":["Servicio de Hematolog\u00eda y Oncolog\u00eda M\u00e9dica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonaci\u00f3n, Universidad de Murcia, IMIB-Arrixaca, U-765, Center for Biomedical Research on Rare Diseases, Murcia, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicio de Hematolog\u00eda y Oncolog\u00eda M\u00e9dica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonaci\u00f3n, Universidad de Murcia, IMIB-Arrixaca, U-765, Center for Biomedical Research on Rare Diseases, Murcia, Spain","institution_ids":["https://openalex.org/I4210091031","https://openalex.org/I4210115362","https://openalex.org/I4210146619","https://openalex.org/I80180929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013491591","display_name":"\u00c1lvaro Garc\u00eda-Hern\u00e1ndez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091031","display_name":"Hospital General Universitario Morales Meseguer","ror":"https://ror.org/00cfm3y81","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210091031"]},{"id":"https://openalex.org/I4210115362","display_name":"Centro Regional de Hemodonaci\u00f3n","ror":"https://ror.org/02a57s352","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210115362"]},{"id":"https://openalex.org/I4210146619","display_name":"Instituto Murciano de Investigaci\u00f3n Biosanitaria","ror":"https://ror.org/053j10c72","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210146619"]},{"id":"https://openalex.org/I80180929","display_name":"Universidad de Murcia","ror":"https://ror.org/03p3aeb86","country_code":"ES","type":"education","lineage":["https://openalex.org/I80180929"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"\u00c1lvaro Garc\u00eda-Hern\u00e1ndez","raw_affiliation_strings":["Servicio de Hematolog\u00eda y Oncolog\u00eda M\u00e9dica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonaci\u00f3n, Universidad de Murcia, IMIB-Arrixaca, U-765, Center for Biomedical Research on Rare Diseases, Murcia, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicio de Hematolog\u00eda y Oncolog\u00eda M\u00e9dica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonaci\u00f3n, Universidad de Murcia, IMIB-Arrixaca, U-765, Center for Biomedical Research on Rare Diseases, Murcia, Spain","institution_ids":["https://openalex.org/I4210091031","https://openalex.org/I4210115362","https://openalex.org/I4210146619","https://openalex.org/I80180929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033392955","display_name":"Vicente Vicente","orcid":"https://orcid.org/0000-0002-4278-3264","observed_orcids":["https://orcid.org/0000-0002-4278-3264"]},"institutions":[{"id":"https://openalex.org/I4210091031","display_name":"Hospital General Universitario Morales Meseguer","ror":"https://ror.org/00cfm3y81","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210091031"]},{"id":"https://openalex.org/I4210115362","display_name":"Centro Regional de Hemodonaci\u00f3n","ror":"https://ror.org/02a57s352","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210115362"]},{"id":"https://openalex.org/I4210146619","display_name":"Instituto Murciano de Investigaci\u00f3n Biosanitaria","ror":"https://ror.org/053j10c72","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210146619"]},{"id":"https://openalex.org/I80180929","display_name":"Universidad de Murcia","ror":"https://ror.org/03p3aeb86","country_code":"ES","type":"education","lineage":["https://openalex.org/I80180929"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Vicente Vicente","raw_affiliation_strings":["Servicio de Hematolog\u00eda y Oncolog\u00eda M\u00e9dica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonaci\u00f3n, Universidad de Murcia, IMIB-Arrixaca, U-765, Center for Biomedical Research on Rare Diseases, Murcia, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicio de Hematolog\u00eda y Oncolog\u00eda M\u00e9dica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonaci\u00f3n, Universidad de Murcia, IMIB-Arrixaca, U-765, Center for Biomedical Research on Rare Diseases, Murcia, Spain","institution_ids":["https://openalex.org/I4210091031","https://openalex.org/I4210115362","https://openalex.org/I4210146619","https://openalex.org/I80180929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078606624","display_name":"Miguel Quintanilla","orcid":"https://orcid.org/0000-0002-2124-7657","observed_orcids":["https://orcid.org/0000-0002-2124-7657"]},"institutions":[{"id":"https://openalex.org/I134820265","display_name":"Consejo Superior de Investigaciones Cient\u00edficas","ror":"https://ror.org/02gfc7t72","country_code":"ES","type":"government","lineage":["https://openalex.org/I134820265"]},{"id":"https://openalex.org/I4210091816","display_name":"Instituto de Investigaciones Biom\u00e9dicas Sols-Morreale","ror":"https://ror.org/00ha1f767","country_code":"ES","type":"facility","lineage":["https://openalex.org/I134820265","https://openalex.org/I4210091816","https://openalex.org/I63634437"]},{"id":"https://openalex.org/I63634437","display_name":"Universidad Aut\u00f3noma de Madrid","ror":"https://ror.org/01cby8j38","country_code":"ES","type":"education","lineage":["https://openalex.org/I63634437"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Miguel Quintanilla","raw_affiliation_strings":["Instituto de Investigaciones Biom\u00e9dicas Alberto Sols, Consejo Superior de Investigaciones Cient\u00edficas (CSIC)-Universidad Aut\u00f3noma de Madrid (UAM), Madrid, Spain. Electronic address: mquintanilla@iib.uam.es","Instituto de Investigaciones Biom\u00e9dicas Alberto Sols, Consejo Superior de Investigaciones Cient\u00edficas (CSIC)-Universidad Aut\u00f3noma de Madrid (UAM), Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Investigaciones Biom\u00e9dicas Alberto Sols, Consejo Superior de Investigaciones Cient\u00edficas (CSIC)-Universidad Aut\u00f3noma de Madrid (UAM), Madrid, Spain. Electronic address: mquintanilla@iib.uam.es","institution_ids":["https://openalex.org/I134820265","https://openalex.org/I4210091816","https://openalex.org/I63634437"]},{"raw_affiliation_string":"Instituto de Investigaciones Biom\u00e9dicas Alberto Sols, Consejo Superior de Investigaciones Cient\u00edficas (CSIC)-Universidad Aut\u00f3noma de Madrid (UAM), Madrid, Spain","institution_ids":["https://openalex.org/I134820265","https://openalex.org/I4210091816","https://openalex.org/I63634437"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063211130","display_name":"Irene Mart\u00ednez\u2010Mart\u00ednez","orcid":"https://orcid.org/0000-0002-1067-6464","observed_orcids":["https://orcid.org/0000-0002-1067-6464"]},"institutions":[{"id":"https://openalex.org/I4210091031","display_name":"Hospital General Universitario Morales Meseguer","ror":"https://ror.org/00cfm3y81","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210091031"]},{"id":"https://openalex.org/I4210115362","display_name":"Centro Regional de Hemodonaci\u00f3n","ror":"https://ror.org/02a57s352","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210115362"]},{"id":"https://openalex.org/I4210146619","display_name":"Instituto Murciano de Investigaci\u00f3n Biosanitaria","ror":"https://ror.org/053j10c72","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210146619"]},{"id":"https://openalex.org/I80180929","display_name":"Universidad de Murcia","ror":"https://ror.org/03p3aeb86","country_code":"ES","type":"education","lineage":["https://openalex.org/I80180929"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Irene Mart\u00ednez-Mart\u00ednez","raw_affiliation_strings":["Servicio de Hematolog\u00eda y Oncolog\u00eda M\u00e9dica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonaci\u00f3n, Universidad de Murcia, IMIB-Arrixaca, U-765, Center for Biomedical Research on Rare Diseases, Murcia, Spain. Electronic address: immlgi@um.es","Servicio de Hematolog\u00eda y Oncolog\u00eda M\u00e9dica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonaci\u00f3n, Universidad de Murcia, IMIB-Arrixaca, U-765, Center for Biomedical Research on Rare Diseases, Murcia, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicio de Hematolog\u00eda y Oncolog\u00eda M\u00e9dica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonaci\u00f3n, Universidad de Murcia, IMIB-Arrixaca, U-765, Center for Biomedical Research on Rare Diseases, Murcia, Spain. Electronic address: immlgi@um.es","institution_ids":["https://openalex.org/I4210115362","https://openalex.org/I4210146619","https://openalex.org/I80180929"]},{"raw_affiliation_string":"Servicio de Hematolog\u00eda y Oncolog\u00eda M\u00e9dica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonaci\u00f3n, Universidad de Murcia, IMIB-Arrixaca, U-765, Center for Biomedical Research on Rare Diseases, Murcia, Spain","institution_ids":["https://openalex.org/I4210091031","https://openalex.org/I4210115362","https://openalex.org/I4210146619","https://openalex.org/I80180929"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5063211130","https://openalex.org/A5078606624"],"corresponding_institution_ids":["https://openalex.org/I134820265","https://openalex.org/I4210091031","https://openalex.org/I4210091816","https://openalex.org/I4210115362","https://openalex.org/I4210146619","https://openalex.org/I63634437","https://openalex.org/I80180929"],"apc_list":{"value":3110,"currency":"USD","value_usd":3110},"apc_paid":null,"fwci":0.2197,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.44763659,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"165","issue":null,"first_page":"245","last_page":"249"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10773","display_name":"Extracellular vesicles in disease","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10773","display_name":"Extracellular vesicles in disease","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antithrombin-iii","display_name":"antithrombin III","score":1.0},{"id":"https://openalex.org/keywords/exosomes","display_name":"exosomes","score":0.9990000128746033},{"id":"https://openalex.org/keywords/htra1","display_name":"HTRA1","score":0.9430000185966492},{"id":"https://openalex.org/keywords/serine-protease-inhibitors","display_name":"serine protease inhibitors","score":0.765999972820282},{"id":"https://openalex.org/keywords/mdck-cells","display_name":"MDCK cells","score":0.6480000019073486},{"id":"https://openalex.org/keywords/heparin","display_name":"heparin","score":0.9369999766349792},{"id":"https://openalex.org/keywords/serum-deprivation","display_name":"serum deprivation","score":0.8859999775886536},{"id":"https://openalex.org/keywords/coagulation-inhibition","display_name":"coagulation inhibition","score":0.7260000109672546},{"id":"https://openalex.org/keywords/hemostasis","display_name":"hemostasis","score":0.703000009059906}],"concepts":[{"id":"https://openalex.org/C2779026020","wikidata":"https://www.wikidata.org/wiki/Q416336","display_name":"Antithrombin","level":3,"score":0.9208580255508423},{"id":"https://openalex.org/C20518536","wikidata":"https://www.wikidata.org/wiki/Q6840469","display_name":"Microvesicles","level":4,"score":0.8468712568283081},{"id":"https://openalex.org/C2778589496","wikidata":"https://www.wikidata.org/wiki/Q487937","display_name":"Hemostasis","level":2,"score":0.6826623678207397},{"id":"https://openalex.org/C2777807008","wikidata":"https://www.wikidata.org/wiki/Q87324999","display_name":"Serine protease","level":4,"score":0.6606452465057373},{"id":"https://openalex.org/C2778382381","wikidata":"https://www.wikidata.org/wiki/Q179217","display_name":"Coagulation","level":2,"score":0.6152018308639526},{"id":"https://openalex.org/C2777557582","wikidata":"https://www.wikidata.org/wiki/Q190016","display_name":"Heparin","level":2,"score":0.5504657626152039},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5459675788879395},{"id":"https://openalex.org/C182220744","wikidata":"https://www.wikidata.org/wiki/Q7251226","display_name":"Proteases","level":3,"score":0.5340064764022827},{"id":"https://openalex.org/C2778965386","wikidata":"https://www.wikidata.org/wiki/Q420068","display_name":"Serpin","level":3,"score":0.48596298694610596},{"id":"https://openalex.org/C2777292125","wikidata":"https://www.wikidata.org/wiki/Q409166","display_name":"Thrombin","level":3,"score":0.4622592329978943},{"id":"https://openalex.org/C2776714187","wikidata":"https://www.wikidata.org/wiki/Q212410","display_name":"Protease","level":3,"score":0.4550893306732178},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.4501490592956543},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3392029404640198},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3214772939682007},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.29085299372673035},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2543978691101074},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.22931823134422302},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20493781566619873},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.17257362604141235},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15836673974990845},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.11298584938049316},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000074289","descriptor_name":"High-Temperature Requirement A Serine Peptidase 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000991","descriptor_name":"Antithrombins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001777","descriptor_name":"Blood Coagulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006493","descriptor_name":"Heparin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D055354","descriptor_name":"Exosomes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D061985","descriptor_name":"Madin Darby Canine Kidney Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.biochi.2019.08.010","doi":"https://doi.org/10.1016/j.biochi.2019.08.010","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.biochi.2019.08.010","pdf_url":null,"source":{"id":"https://openalex.org/S75247133","display_name":"Biochimie","issn_l":"0037-9042","issn":["0037-9042","0300-9084","1638-6183"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimie","raw_type":"journal-article"},{"id":"pmid:31445073","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31445073","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimie","raw_type":"Journal Article"},{"id":"pmh:oai:digital.csic.es:10261/206302","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10261/206302","pdf_url":null,"source":{"id":"https://openalex.org/S4306400616","display_name":"DIGITAL.CSIC (Spanish National Research Council (CSIC))","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I134820265","host_organization_name":"Consejo Superior de Investigaciones Cient\u00edficas","host_organization_lineage":["https://openalex.org/I134820265"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"http://purl.org/coar/resource_type/c_6501"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8199999928474426,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1946092100","display_name":null,"funder_award_id":"CP13/00126","funder_id":"https://openalex.org/F4320334923","funder_display_name":"Instituto de Salud Carlos III"},{"id":"https://openalex.org/G5149953504","display_name":null,"funder_award_id":"PI17/00050","funder_id":"https://openalex.org/F4320321595","funder_display_name":"Federaci\u00f3n Espa\u00f1ola de Enfermedades Raras"}],"funders":[{"id":"https://openalex.org/F4320321595","display_name":"Federaci\u00f3n Espa\u00f1ola de Enfermedades Raras","ror":"https://ror.org/0348bpk17"},{"id":"https://openalex.org/F4320325369","display_name":"Sociedad Espa\u00f1ola de Hematolog\u00eda y Hemoterapia","ror":"https://ror.org/0532s5p48"},{"id":"https://openalex.org/F4320334923","display_name":"Instituto de Salud Carlos III","ror":"https://ror.org/00ca2c886"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1521666809","https://openalex.org/W2000335482","https://openalex.org/W2024193507","https://openalex.org/W2045350382","https://openalex.org/W2045473459","https://openalex.org/W2098259366","https://openalex.org/W2134584636","https://openalex.org/W2170743542","https://openalex.org/W2171215167","https://openalex.org/W2292499241","https://openalex.org/W2410839454","https://openalex.org/W2738355617","https://openalex.org/W2943261504"],"related_works":["https://openalex.org/W2057382122","https://openalex.org/W4386296205","https://openalex.org/W2154361044","https://openalex.org/W2085545463","https://openalex.org/W1479833274","https://openalex.org/W2018080575","https://openalex.org/W6993192170","https://openalex.org/W7099062263","https://openalex.org/W2002600260","https://openalex.org/W177249405"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-08-29T00:00:00"}