{"id":"https://openalex.org/W296902466","doi":null,"title":"Influence of small mechanical head injuries on peripheral blood natural killer cytotoxicity (NKCC) in rats.","display_name":"Influence of small mechanical head injuries on peripheral blood natural killer cytotoxicity (NKCC) in rats.","publication_year":2004,"publication_date":"2004-01-01","ids":{"openalex":"https://openalex.org/W296902466","mag":"296902466","pmid":"https://pubmed.ncbi.nlm.nih.gov/15266783"},"language":"en","primary_location":{"id":"pmid:15266783","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15266783","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Folia neuropathologica","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015902007","display_name":"Marek Kajetan Jurkowski","orcid":"https://orcid.org/0000-0002-8005-5524","observed_orcids":["https://orcid.org/0000-0002-8005-5524"]},"institutions":[{"id":"https://openalex.org/I75124487","display_name":"Gda\u0144sk Medical University","ror":"https://ror.org/019sbgd69","country_code":"PL","type":"education","lineage":["https://openalex.org/I75124487"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Marek K Jurkowski","raw_affiliation_strings":["Department of Anatomy and Neurobiology, Medical University of Gda\u0144sk, Gda\u0144sk, Poland. marjur51@poczta.onet.pl"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy and Neurobiology, Medical University of Gda\u0144sk, Gda\u0144sk, Poland. marjur51@poczta.onet.pl","institution_ids":["https://openalex.org/I75124487"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073154117","display_name":"Barbara Bobek\u2010Billewicz","orcid":"https://orcid.org/0000-0003-3262-9738","observed_orcids":["https://orcid.org/0000-0003-3262-9738"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Barbara Bobek-Billewicz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"42","issue":"2","first_page":"93","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12626","display_name":"Cancer, Stress, Anesthesia, and Immune Response","score":0.7821999788284302,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12626","display_name":"Cancer, Stress, Anesthesia, and Immune Response","score":0.7821999788284302,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.07090000063180923,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.043800000101327896,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/natural-killer-cells","display_name":"natural killer cells","score":0.7670000195503235},{"id":"https://openalex.org/keywords/nk-cell-cytotoxicity","display_name":"NK cell cytotoxicity","score":0.8240000009536743},{"id":"https://openalex.org/keywords/brain-injury","display_name":"brain injury","score":0.4699999988079071},{"id":"https://openalex.org/keywords/skull-injuries","display_name":"skull injuries","score":0.8159999847412109},{"id":"https://openalex.org/keywords/electrode-implantation","display_name":"electrode implantation","score":0.6809999942779541},{"id":"https://openalex.org/keywords/large-granular-lymphocytes","display_name":"large granular lymphocytes","score":0.7639999985694885},{"id":"https://openalex.org/keywords/corticosterone","display_name":"corticosterone","score":0.8629999756813049},{"id":"https://openalex.org/keywords/anesthesia","display_name":"anesthesia","score":0.6389999985694885},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.7860000133514404},{"id":"https://openalex.org/keywords/brain-stimulation","display_name":"brain stimulation","score":0.5059999823570251},{"id":"https://openalex.org/keywords/rats","display_name":"rats","score":0.3709999918937683}],"concepts":[{"id":"https://openalex.org/C2779300802","wikidata":"https://www.wikidata.org/wiki/Q13147","display_name":"Skull","level":2,"score":0.668350100517273},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5722029805183411},{"id":"https://openalex.org/C2776403516","wikidata":"https://www.wikidata.org/wiki/Q268930","display_name":"Meninges","level":2,"score":0.5551841855049133},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.49845409393310547},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.47646093368530273},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3999427855014801},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.3660927414894104},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.28295058012008667},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.23066547513008118},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.18843230605125427}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003602","descriptor_name":"Cytotoxicity, Immunologic","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006259","descriptor_name":"Craniocerebral Trauma","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007694","descriptor_name":"Killer Cells, Natural","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D007694","descriptor_name":"Killer Cells, Natural","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008213","descriptor_name":"Lymphocyte Activation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018655","descriptor_name":"Lymphocyte Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:15266783","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15266783","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Folia neuropathologica","raw_type":"Comparative Study"},{"id":"mag:296902466","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15266783","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W13863626","https://openalex.org/W185718323","https://openalex.org/W1496877897","https://openalex.org/W1971054448","https://openalex.org/W1976378044","https://openalex.org/W1983764257","https://openalex.org/W1986395580","https://openalex.org/W1991481781","https://openalex.org/W2010710307","https://openalex.org/W2012740861","https://openalex.org/W2014847742","https://openalex.org/W2019134681","https://openalex.org/W2023437761","https://openalex.org/W2031510544","https://openalex.org/W2034450006","https://openalex.org/W2038491082","https://openalex.org/W2038614866","https://openalex.org/W2044135666","https://openalex.org/W2045964137","https://openalex.org/W2062392962","https://openalex.org/W2068072779","https://openalex.org/W2074302157","https://openalex.org/W2085121871","https://openalex.org/W2093738970","https://openalex.org/W2110784907","https://openalex.org/W2111565797","https://openalex.org/W2113556355","https://openalex.org/W2115352319","https://openalex.org/W2125066559","https://openalex.org/W2148502880","https://openalex.org/W2155172444","https://openalex.org/W2163815564","https://openalex.org/W2216567358","https://openalex.org/W2317588397","https://openalex.org/W2404229698","https://openalex.org/W2438686387","https://openalex.org/W2463484420"],"related_works":["https://openalex.org/W2038491082","https://openalex.org/W2029795940","https://openalex.org/W2419021382","https://openalex.org/W2007264874","https://openalex.org/W7099784834","https://openalex.org/W2153285493","https://openalex.org/W2003605951","https://openalex.org/W2413390480","https://openalex.org/W1983751293","https://openalex.org/W2073275468"],"abstract_inverted_index":{"Many":[0],"neurophysiological":[1],"experiments":[2],"and":[3,19,48,51,71,108,118,129,158,171,202],"some":[4,27,190],"human's":[5],"brain":[6,20,49,72,83,192],"tissue":[7,21,73,84,193],"stimulatory":[8],"therapies":[9],"require":[10],"surgery":[11],"intervention,":[12],"which":[13,33,113],"results":[14,123,187],"in":[15,94],"small":[16,68,126,191],"mechanical":[17,69,127],"skull":[18,70,128,151,163],"injuries.":[22],"Additionally,":[23,100],"these":[24],"procedures":[25],"need":[26],"local":[28],"or":[29,81,132],"short":[30],"general":[31],"anaesthesia,":[32],"is":[34],"not":[35,136],"neutral":[36],"for":[37,79],"immune":[38],"system":[39],"action.":[40],"Clinical":[41],"data":[42],"unambiguously":[43],"shows":[44],"that":[45,125,189],"severe":[46],"head":[47],"injuries":[50,131,194],"anaesthesia":[52],"can":[53],"suppress":[54],"immunity.":[55],"The":[56,122],"aim":[57],"of":[58,67,105,200],"the":[59,65,150,162,178,182,186,198],"present":[60],"study":[61],"was":[62],"to":[63],"investigate":[64],"influence":[66,197],"injuries,":[74],"accompanied":[75],"by":[76,144],"electrode":[77,145,154,183],"fixation":[78],"experimental":[80],"therapeutic":[82],"stimulation,":[85],"on":[86,177],"peripheral":[87],"blood":[88],"natural":[89],"killer":[90],"cytotoxicity":[91],"(NKCC)":[92],"assessed":[93,102],"a":[95,103],"4h":[96],"standard":[97],"cytotoxic":[98],"test.":[99],"we":[101],"number":[104,173,199],"leukocytes,":[106],"lymphocytes":[107,111],"large":[109],"granular":[110],"(LGL),":[112],"are":[114],"NK":[115],"cell":[116],"subset":[117],"plasma":[119],"corticosterone":[120],"concentration.":[121],"showed":[124,188],"meninges":[130],"alone-administered":[133],"Nembutal":[134],"did":[135],"evoke":[137],"any":[138],"significant":[139],"changes":[140],"as":[141],"those":[142],"caused":[143],"placement":[146],"4.2":[147],"mm":[148,160],"below":[149,161],"surface.":[152],"Deeper":[153],"fixation,":[155],"6.1;":[156],"7.6":[157],"8.4":[159],"surface,":[164],"significantly":[165],"increased":[166],"NKCC":[167],"(p":[168,174],"<":[169,175],"0.05)":[170,176],"LGL":[172,201],"3rd":[179],"day":[180],"after":[181],"placement.":[184],"Moreover,":[185],"could":[195],"transiently":[196],"NKCC.":[203]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}