{"id":"https://openalex.org/W29688246","doi":null,"title":"Primitive multipotential primary sarcoma of bone: a case report and immunohistochemical study.","display_name":"Primitive multipotential primary sarcoma of bone: a case report and immunohistochemical study.","publication_year":1991,"publication_date":"1991-11-01","ids":{"openalex":"https://openalex.org/W29688246","mag":"29688246","pmid":"https://pubmed.ncbi.nlm.nih.gov/1724089"},"language":"en","primary_location":{"id":"pmid:1724089","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1724089","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc","raw_type":"Case Reports"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057910920","display_name":"Cheryl Frydman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C P Frydman","raw_affiliation_strings":["Lillian and Henry F. Stratton-Hans Popper Department of Pathology, Mount Sinai School of Medicine, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lillian and Henry F. Stratton-Hans Popper Department of Pathology, Mount Sinai School of Medicine, New York, New York","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003671243","display_name":"Michael J. Klein","orcid":"https://orcid.org/0000-0002-5186-8120","observed_orcids":["https://orcid.org/0000-0002-5186-8120"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M J Klein","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109078486","display_name":"I F Abdelwahab","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"I F Abdelwahab","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5054381531","display_name":"Alicia Zwass","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Zwass","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2395,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.56489648,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"4","issue":"6","first_page":"768","last_page":"72"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10975","display_name":"Bone Tumor Diagnosis and Treatments","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11638","display_name":"Cardiac tumors and thrombi","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/primary-bone-sarcoma","display_name":"primary bone sarcoma","score":0.8080000281333923},{"id":"https://openalex.org/keywords/multipotential-differentiation","display_name":"multipotential differentiation","score":0.9179999828338623},{"id":"https://openalex.org/keywords/epithelial-differentiation","display_name":"epithelial differentiation","score":0.8320000171661377},{"id":"https://openalex.org/keywords/osteosarcomatous-differentiation","display_name":"osteosarcomatous differentiation","score":0.8759999871253967},{"id":"https://openalex.org/keywords/proximal-tibia","display_name":"proximal tibia","score":0.703000009059906},{"id":"https://openalex.org/keywords/tarsal-bones","display_name":"tarsal bones","score":0.6850000023841858},{"id":"https://openalex.org/keywords/lung-metastasis","display_name":"lung metastasis","score":0.8700000047683716},{"id":"https://openalex.org/keywords/mesenchymal-tumors","display_name":"mesenchymal tumors","score":0.828000009059906},{"id":"https://openalex.org/keywords/immunohistochemical-markers","display_name":"immunohistochemical markers","score":0.859000027179718},{"id":"https://openalex.org/keywords/epithelial-markers","display_name":"epithelial markers","score":0.6850000023841858},{"id":"https://openalex.org/keywords/leukocyte-markers","display_name":"leukocyte markers","score":0.9459999799728394}],"concepts":[{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.8369258642196655},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.7521665692329407},{"id":"https://openalex.org/C81880429","wikidata":"https://www.wikidata.org/wiki/Q2035067","display_name":"Osteoid","level":2,"score":0.6833059787750244},{"id":"https://openalex.org/C2777760704","wikidata":"https://www.wikidata.org/wiki/Q549534","display_name":"Osteosarcoma","level":2,"score":0.542680561542511},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5072219371795654},{"id":"https://openalex.org/C2778256501","wikidata":"https://www.wikidata.org/wiki/Q223911","display_name":"Sarcoma","level":2,"score":0.5057077407836914},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2674909830093384}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001859","descriptor_name":"Bone Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001859","descriptor_name":"Bone Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001859","descriptor_name":"Bone Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011859","descriptor_name":"Radiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012509","descriptor_name":"Sarcoma","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D012509","descriptor_name":"Sarcoma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012509","descriptor_name":"Sarcoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D013194","descriptor_name":"Staining and Labeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:1724089","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1724089","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc","raw_type":"Case Reports"},{"id":"mag:29688246","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1724089","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8560000061988831,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1559451164","https://openalex.org/W2000445173","https://openalex.org/W2025056766","https://openalex.org/W2103776580","https://openalex.org/W2121656227","https://openalex.org/W2150342670","https://openalex.org/W2153054970","https://openalex.org/W2159909853","https://openalex.org/W2164186760","https://openalex.org/W2165724006","https://openalex.org/W2266179496","https://openalex.org/W2413457902","https://openalex.org/W2527588861","https://openalex.org/W6746694045"],"related_works":["https://openalex.org/W2034191125","https://openalex.org/W2128510193","https://openalex.org/W1967276375","https://openalex.org/W2014178673","https://openalex.org/W2389621977","https://openalex.org/W2257356206","https://openalex.org/W4283695276","https://openalex.org/W2063224488","https://openalex.org/W2444362924","https://openalex.org/W4311477209"],"abstract_inverted_index":{"A":[0],"tumor":[1,40,88],"initially":[2],"presenting":[3],"as":[4],"a":[5,14,85,123],"round":[6,31],"cell":[7,32],"sarcoma":[8],"in":[9,59,66,74,84,116,122],"the":[10,20,26,39,54,97],"proximal":[11],"tibia":[12],"of":[13,38,56,61,68,76,81,96],"42-yr-old":[15],"male":[16],"disseminated":[17],"to":[18,30],"involve":[19],"femur,":[21],"multiple":[22],"tarsal":[23],"bones,":[24],"and":[25,44,71,91,115],"lungs.":[27],"In":[28],"addition":[29],"areas":[33,37,47,60,67,75],"resembling":[34],"lymphoma,":[35],"other":[36,46],"produced":[41],"osteoid":[42],"matrix":[43],"still":[45],"suggested":[48],"epithelial":[49,57,62,82,111],"differentiation.":[50,78],"Immunohistochemical":[51],"staining":[52],"revealed":[53],"presence":[55,101],"markers":[58,65],"differentiation,":[63,70],"leukocyte":[64],"lymphomatous":[69],"neither":[72,110],"marker":[73],"osteosarcomatous":[77],"The":[79,105],"finding":[80],"elements":[83],"primary":[86],"bone":[87],"is":[89,94],"rare,":[90],"this":[92],"report":[93],"one":[95],"first":[98],"confirming":[99],"their":[100],"using":[102],"immunohistochemical":[103],"markers.":[104],"findings":[106],"are":[107],"consonant":[108],"for":[109],"nor":[112],"lymphoid":[113],"neoplasms":[114],"all":[117],"probability":[118],"represent":[119],"multipotential":[120],"differentiation":[121],"primitive":[124],"mesenchymal":[125],"tumor.":[126]},"counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}