{"id":"https://openalex.org/W2967775191","doi":"https://doi.org/10.1161/jaha.118.011130","title":"Epoetin Beta and C\u2010Terminal Fibroblast Growth Factor 23 in Patients With Chronic Heart Failure and Chronic Kidney Disease","display_name":"Epoetin Beta and C\u2010Terminal Fibroblast Growth Factor 23 in Patients With Chronic Heart Failure and Chronic Kidney Disease","publication_year":2019,"publication_date":"2019-08-17","ids":{"openalex":"https://openalex.org/W2967775191","doi":"https://doi.org/10.1161/jaha.118.011130","mag":"2967775191","pmid":"https://pubmed.ncbi.nlm.nih.gov/31423921"},"language":"en","primary_location":{"id":"doi:10.1161/jaha.118.011130","doi":"https://doi.org/10.1161/jaha.118.011130","is_oa":true,"landing_page_url":"https://doi.org/10.1161/jaha.118.011130","pdf_url":null,"source":{"id":"https://openalex.org/S2489920150","display_name":"Journal of the American Heart Association","issn_l":"2047-9980","issn":["2047-9980"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Heart Association","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1161/jaha.118.011130","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088158212","display_name":"Michele Freerk Eisenga","orcid":"https://orcid.org/0000-0002-2484-6233","observed_orcids":["https://orcid.org/0000-0002-2484-6233"]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]},{"id":"https://openalex.org/I169381384","display_name":"University of Groningen","ror":"https://ror.org/012p63287","country_code":"NL","type":"education","lineage":["https://openalex.org/I169381384"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Michele F. Eisenga","raw_affiliation_strings":["Division of Nephrology Department of Internal Medicine University of Groningen University Medical Center Groningen Groningen the Netherlands","Michele F. Eisenga Division of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology Department of Internal Medicine University of Groningen University Medical Center Groningen Groningen the Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]},{"raw_affiliation_string":"Michele F. Eisenga Division of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088798295","display_name":"Mireille E. Emans","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210103644","display_name":"Ikazia Ziekenhuis","ror":"https://ror.org/01abkkw91","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210103644"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Mireille E. Emans","raw_affiliation_strings":["Department of Cardiology Ikazia Hospital Rotterdam the Netherlands","Mireille E. Emans Department of Cardiology, Ikazia Hospital, Rotterdam, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology Ikazia Hospital Rotterdam the Netherlands","institution_ids":["https://openalex.org/I4210103644"]},{"raw_affiliation_string":"Mireille E. Emans Department of Cardiology, Ikazia Hospital, Rotterdam, the Netherlands","institution_ids":["https://openalex.org/I4210103644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035043783","display_name":"Karien van der Putten","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210147058","display_name":"Tergooi","ror":"https://ror.org/045nawc23","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210147058"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Karien van der Putten","raw_affiliation_strings":["Department of Nephrology Tergooi Hospital Hilversum the Netherlands","Karien van der Putten Department of Nephrology, Tergooi Hospital, Hilversum, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology Tergooi Hospital Hilversum the Netherlands","institution_ids":["https://openalex.org/I4210147058"]},{"raw_affiliation_string":"Karien van der Putten Department of Nephrology, Tergooi Hospital, Hilversum, the Netherlands","institution_ids":["https://openalex.org/I4210147058"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044679752","display_name":"Maarten Jan Cramer","orcid":"https://orcid.org/0000-0002-6041-6759","observed_orcids":["https://orcid.org/0000-0002-6041-6759"]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]},{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Maarten J. Cramer","raw_affiliation_strings":["Department of Cardiology University of Utrecht University Medical Center Utrecht Utrecht the Netherlands","Maarten J. Cramer Department of Cardiology, University of Utrecht, University Medical Center Utrecht, Utrecht, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology University of Utrecht University Medical Center Utrecht Utrecht the Netherlands","institution_ids":["https://openalex.org/I193662353","https://openalex.org/I3018483916"]},{"raw_affiliation_string":"Maarten J. Cramer Department of Cardiology, University of Utrecht, University Medical Center Utrecht, Utrecht, the Netherlands","institution_ids":["https://openalex.org/I193662353","https://openalex.org/I3018483916"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079889801","display_name":"Adry Diepenbroek","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]},{"id":"https://openalex.org/I169381384","display_name":"University of Groningen","ror":"https://ror.org/012p63287","country_code":"NL","type":"education","lineage":["https://openalex.org/I169381384"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Adry Diepenbroek","raw_affiliation_strings":["Division of Nephrology Department of Internal Medicine University of Groningen University Medical Center Groningen Groningen the Netherlands","Adry Diepenbroek Division of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology Department of Internal Medicine University of Groningen University Medical Center Groningen Groningen the Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]},{"raw_affiliation_string":"Adry Diepenbroek Division of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069986738","display_name":"Birgitta K. Velthuis","orcid":"https://orcid.org/0000-0002-2542-9474","observed_orcids":["https://orcid.org/0000-0002-2542-9474"]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]},{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Birgitta K. Velthuis","raw_affiliation_strings":["Department of Radiology University of Utrecht University Medical Center Utrecht Utrecht the Netherlands","Birgitta K. Velthuis Department of Radiology, University of Utrecht, University Medical Center Utrecht, Utrecht, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology University of Utrecht University Medical Center Utrecht Utrecht the Netherlands","institution_ids":["https://openalex.org/I193662353","https://openalex.org/I3018483916"]},{"raw_affiliation_string":"Birgitta K. Velthuis Department of Radiology, University of Utrecht, University Medical Center Utrecht, Utrecht, the Netherlands","institution_ids":["https://openalex.org/I193662353","https://openalex.org/I3018483916"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081338491","display_name":"Pieter A. Doevendans","orcid":"https://orcid.org/0000-0002-6257-7169","observed_orcids":["https://orcid.org/0000-0002-6257-7169"]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]},{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Pieter A. Doevendans","raw_affiliation_strings":["Department of Cardiology University of Utrecht University Medical Center Utrecht Utrecht the Netherlands","Pieter A. Doevendans Department of Cardiology, University of Utrecht, University Medical Center Utrecht, Utrecht, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology University of Utrecht University Medical Center Utrecht Utrecht the Netherlands","institution_ids":["https://openalex.org/I193662353","https://openalex.org/I3018483916"]},{"raw_affiliation_string":"Pieter A. Doevendans Department of Cardiology, University of Utrecht, University Medical Center Utrecht, Utrecht, the Netherlands","institution_ids":["https://openalex.org/I193662353","https://openalex.org/I3018483916"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065455968","display_name":"Marianne Christina Verhaar","orcid":"https://orcid.org/0000-0002-3276-6428","observed_orcids":["https://orcid.org/0000-0002-3276-6428"]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]},{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Marianne C. Verhaar","raw_affiliation_strings":["Department of Nephrology and Hypertension University of Utrecht University Medical Center Utrecht Utrecht the Netherlands","Marianne C. Verhaar Department of Nephrology and Hypertension, University of Utrecht, University Medical Center Utrecht, Utrecht, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology and Hypertension University of Utrecht University Medical Center Utrecht Utrecht the Netherlands","institution_ids":["https://openalex.org/I193662353","https://openalex.org/I3018483916"]},{"raw_affiliation_string":"Marianne C. Verhaar Department of Nephrology and Hypertension, University of Utrecht, University Medical Center Utrecht, Utrecht, the Netherlands","institution_ids":["https://openalex.org/I193662353","https://openalex.org/I3018483916"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062438369","display_name":"Jaap A. Joles","orcid":"https://orcid.org/0000-0003-2565-242X","observed_orcids":["https://orcid.org/0000-0003-2565-242X"]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]},{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Jaap A. Joles","raw_affiliation_strings":["Department of Nephrology and Hypertension University of Utrecht University Medical Center Utrecht Utrecht the Netherlands","Jaap A. Joles Department of Nephrology and Hypertension, University of Utrecht, University Medical Center Utrecht, Utrecht, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology and Hypertension University of Utrecht University Medical Center Utrecht Utrecht the Netherlands","institution_ids":["https://openalex.org/I193662353","https://openalex.org/I3018483916"]},{"raw_affiliation_string":"Jaap A. Joles Department of Nephrology and Hypertension, University of Utrecht, University Medical Center Utrecht, Utrecht, the Netherlands","institution_ids":["https://openalex.org/I193662353","https://openalex.org/I3018483916"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038949732","display_name":"Stephan J. L. Bakker","orcid":"https://orcid.org/0000-0003-3356-6791","observed_orcids":["https://orcid.org/0000-0003-3356-6791"]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]},{"id":"https://openalex.org/I169381384","display_name":"University of Groningen","ror":"https://ror.org/012p63287","country_code":"NL","type":"education","lineage":["https://openalex.org/I169381384"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Stephan J. L. Bakker","raw_affiliation_strings":["Division of Nephrology Department of Internal Medicine University of Groningen University Medical Center Groningen Groningen the Netherlands","Stephan J. L. Bakker Division of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology Department of Internal Medicine University of Groningen University Medical Center Groningen Groningen the Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]},{"raw_affiliation_string":"Stephan J. L. Bakker Division of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009803531","display_name":"Ilja Maria Nolte","orcid":"https://orcid.org/0000-0001-5047-4077","observed_orcids":["https://orcid.org/0000-0001-5047-4077"]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]},{"id":"https://openalex.org/I169381384","display_name":"University of Groningen","ror":"https://ror.org/012p63287","country_code":"NL","type":"education","lineage":["https://openalex.org/I169381384"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Ilja M. Nolte","raw_affiliation_strings":["Department of Epidemiology University of Groningen University Medical Center Groningen Groningen the Netherlands","Ilja M. Nolte Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology University of Groningen University Medical Center Groningen Groningen the Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]},{"raw_affiliation_string":"Ilja M. Nolte Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023504201","display_name":"Branko G. Braam","orcid":"https://orcid.org/0000-0002-7296-1148","observed_orcids":["https://orcid.org/0000-0002-7296-1148"]},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Branko Braam","raw_affiliation_strings":["Division of Nephrology and Immunology Department of Medicine University of Alberta Edmonton Canada","Branko Braam Division of Nephrology and Immunology, Department of Medicine, University of Alberta, Edmonton, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology and Immunology Department of Medicine University of Alberta Edmonton Canada","institution_ids":["https://openalex.org/I154425047"]},{"raw_affiliation_string":"Branko Braam Division of Nephrology and Immunology, Department of Medicine, University of Alberta, Edmonton, Canada","institution_ids":["https://openalex.org/I154425047"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061326625","display_name":"Sandrine Gaillard","orcid":"https://orcid.org/0000-0002-8964-0236","observed_orcids":["https://orcid.org/0000-0002-8964-0236"]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]},{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Carlo A. J. M. Gaillard","raw_affiliation_strings":["Department of Internal Medicine and Dermatology University of Utrecht University Medical Center Utrecht Utrecht the Netherlands","Carlo A. J. M. Gaillard Department of Internal Medicine and Dermatology, University of Utrecht, University Medical Center Utrecht, Utrecht, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine and Dermatology University of Utrecht University Medical Center Utrecht Utrecht the Netherlands","institution_ids":["https://openalex.org/I193662353","https://openalex.org/I3018483916"]},{"raw_affiliation_string":"Carlo A. J. M. Gaillard Department of Internal Medicine and Dermatology, University of Utrecht, University Medical Center Utrecht, Utrecht, the Netherlands","institution_ids":["https://openalex.org/I193662353","https://openalex.org/I3018483916"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2750,"currency":"USD","value_usd":2750},"apc_paid":{"value":2750,"currency":"USD","value_usd":2750},"fwci":1.5109,"has_fulltext":true,"cited_by_count":22,"citation_normalized_percentile":{"value":0.83273343,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":98},"biblio":{"volume":"8","issue":"16","first_page":"e011130","last_page":"e011130"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11534","display_name":"Erythropoietin and Anemia Treatment","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11534","display_name":"Erythropoietin and Anemia Treatment","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/epoetin-beta","display_name":"epoetin beta","score":0.9980000257492065},{"id":"https://openalex.org/keywords/erythropoiesis-stimulating-agents","display_name":"erythropoiesis-stimulating agents","score":0.9369999766349792},{"id":"https://openalex.org/keywords/fgf23","display_name":"fibroblast growth factor 23","score":0.9279999732971191},{"id":"https://openalex.org/keywords/c-terminal-fgf23","display_name":"C-terminal FGF23","score":0.972000002861023},{"id":"https://openalex.org/keywords/chronic-heart-failure","display_name":"chronic heart failure","score":0.9810000061988831},{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":1.0},{"id":"https://openalex.org/keywords/anemia","display_name":"anemia","score":0.9350000023841858},{"id":"https://openalex.org/keywords/mortality-risk","display_name":"mortality risk","score":0.8420000076293945},{"id":"https://openalex.org/keywords/cardiovascular-outcomes","display_name":"cardiovascular outcomes","score":0.5899999737739563}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8762043714523315},{"id":"https://openalex.org/C2778534260","wikidata":"https://www.wikidata.org/wiki/Q218706","display_name":"Erythropoietin","level":2,"score":0.8703693151473999},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.7143937945365906},{"id":"https://openalex.org/C2778248108","wikidata":"https://www.wikidata.org/wiki/Q5445","display_name":"Anemia","level":2,"score":0.6479848623275757},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6422790884971619},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.5788792371749878},{"id":"https://openalex.org/C114276007","wikidata":"https://www.wikidata.org/wiki/Q14897899","display_name":"Fibroblast growth factor 23","level":4,"score":0.5588750839233398},{"id":"https://openalex.org/C2780959883","wikidata":"https://www.wikidata.org/wiki/Q111146","display_name":"Hematocrit","level":2,"score":0.536749005317688},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.528529167175293},{"id":"https://openalex.org/C119060515","wikidata":"https://www.wikidata.org/wiki/Q1916617","display_name":"Interquartile range","level":2,"score":0.5030073523521423},{"id":"https://openalex.org/C2778917026","wikidata":"https://www.wikidata.org/wiki/Q43041","display_name":"Hemoglobin","level":2,"score":0.4117073714733124},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.38792648911476135},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.36651137471199036},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.05094391107559204},{"id":"https://openalex.org/C2781208988","wikidata":"https://www.wikidata.org/wiki/Q202476","display_name":"Parathyroid hormone","level":3,"score":0.0},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000089703","descriptor_name":"Fibroblast Growth Factor-23","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000089703","descriptor_name":"Fibroblast Growth Factor-23","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000089703","descriptor_name":"Fibroblast Growth Factor-23","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000740","descriptor_name":"Anemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000740","descriptor_name":"Anemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000740","descriptor_name":"Anemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000740","descriptor_name":"Anemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D000740","descriptor_name":"Anemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D000740","descriptor_name":"Anemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D000740","descriptor_name":"Anemia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D000740","descriptor_name":"Anemia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D000740","descriptor_name":"Anemia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D004921","descriptor_name":"Erythropoietin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D004921","descriptor_name":"Erythropoietin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D004921","descriptor_name":"Erythropoietin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005346","descriptor_name":"Fibroblast Growth Factors","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D005346","descriptor_name":"Fibroblast Growth Factors","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D005346","descriptor_name":"Fibroblast Growth Factors","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006397","descriptor_name":"Hematinics","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006397","descriptor_name":"Hematinics","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006397","descriptor_name":"Hematinics","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006454","descriptor_name":"Hemoglobins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006454","descriptor_name":"Hemoglobins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006454","descriptor_name":"Hemoglobins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false}],"locations_count":8,"locations":[{"id":"doi:10.1161/jaha.118.011130","doi":"https://doi.org/10.1161/jaha.118.011130","is_oa":true,"landing_page_url":"https://doi.org/10.1161/jaha.118.011130","pdf_url":null,"source":{"id":"https://openalex.org/S2489920150","display_name":"Journal of the American Heart Association","issn_l":"2047-9980","issn":["2047-9980"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Heart Association","raw_type":"journal-article"},{"id":"pmid:31423921","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31423921","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Heart Association","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6759901","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6759901","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Am Heart Assoc","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:baf6c377b3794abc9b1eaaa51c0774c2","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/baf6c377b3794abc9b1eaaa51c0774c2","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 16 (2019)","raw_type":"article"},{"id":"pmh:oai:dspace.library.uu.nl:1874/387602","doi":null,"is_oa":true,"landing_page_url":"https://dspace.library.uu.nl/handle/1874/387602","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:pure.rug.nl:openaire/6467ad6e-6ecb-488c-aba6-c51bcc626439","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/11370/6467ad6e-6ecb-488c-aba6-c51bcc626439","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Eisenga, M F, Emans, M E, van der Putten, K, Cramer, M J, Diepenbroek, A, Velthuis, B K, Doevendans, P A, Verhaar, M C, Joles, J A, Bakker, S J L, Nolte, I M, Braam, B & Gaillard, C A J M 2019, 'Epoetin Beta and C-Terminal Fibroblast Growth Factor 23 in Patients With Chronic Heart Failure and Chronic Kidney Disease', Journal of the American Heart Association, vol. 8, no. 16, e011130. https://doi.org/10.1161/JAHA.118.011130","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:rug:oai:pure.rug.nl:publications/6467ad6e-6ecb-488c-aba6-c51bcc626439","doi":null,"is_oa":true,"landing_page_url":"https://research.rug.nl/en/publications/6467ad6e-6ecb-488c-aba6-c51bcc626439","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of the American Heart Association, 8(16):e011130. Wiley","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:umcu:oai:dspace.library.uu.nl:1874/387602","doi":null,"is_oa":true,"landing_page_url":"https://dspace.library.uu.nl/handle/1874/387602","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of the American Heart Association, 8(16). Wiley-Blackwell","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1161/jaha.118.011130","doi":"https://doi.org/10.1161/jaha.118.011130","is_oa":true,"landing_page_url":"https://doi.org/10.1161/jaha.118.011130","pdf_url":null,"source":{"id":"https://openalex.org/S2489920150","display_name":"Journal of the American Heart Association","issn_l":"2047-9980","issn":["2047-9980"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Heart Association","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.8799999952316284,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W145334081","https://openalex.org/W1549105976","https://openalex.org/W1965859444","https://openalex.org/W1977645780","https://openalex.org/W2003478281","https://openalex.org/W2010494541","https://openalex.org/W2015668150","https://openalex.org/W2025952915","https://openalex.org/W2039049441","https://openalex.org/W2040029744","https://openalex.org/W2048549852","https://openalex.org/W2067304757","https://openalex.org/W2077450041","https://openalex.org/W2107420262","https://openalex.org/W2131211719","https://openalex.org/W2133586571","https://openalex.org/W2133712226","https://openalex.org/W2134487085","https://openalex.org/W2136542175","https://openalex.org/W2137591192","https://openalex.org/W2142941428","https://openalex.org/W2152182062","https://openalex.org/W2153211549","https://openalex.org/W2155566139","https://openalex.org/W2220231666","https://openalex.org/W2426424112","https://openalex.org/W2511605914","https://openalex.org/W2530806234","https://openalex.org/W2542211819","https://openalex.org/W2744733435","https://openalex.org/W2747440274","https://openalex.org/W2753738233","https://openalex.org/W2764148593","https://openalex.org/W2765775488","https://openalex.org/W2770362275","https://openalex.org/W2787099426","https://openalex.org/W2789330893","https://openalex.org/W2830773612"],"related_works":["https://openalex.org/W2243180194","https://openalex.org/W2140502152","https://openalex.org/W1552381745","https://openalex.org/W2051884508","https://openalex.org/W1922001883","https://openalex.org/W2589670226","https://openalex.org/W2135740653","https://openalex.org/W2060131692","https://openalex.org/W2160789753","https://openalex.org/W2099453712"],"abstract_inverted_index":{"Background":[0],"In":[1,79],"patients":[2,63,91,259],"with":[3,14,23,53,64,101,182,199,235,260],"chronic":[4,8,66,70,103,107,261,265],"heart":[5,67,104,262],"failure":[6,68,105,263],"and":[7,30,69,77,106,126,138,142,160,255,264],"kidney":[9,71,108,266],"disease,":[10],"correction":[11],"of":[12,27,38,48,59,113,155,202,222,227,239],"anemia":[13],"erythropoietin-stimulating":[15,60,156,178],"agents":[16,61,179],"targeting":[17],"normal":[18],"hemoglobin":[19,161],"levels":[20,47,162,195,217,226],"is":[21],"associated":[22,52,198,234],"an":[24,236],"increased":[25,200,237],"risk":[26,201,238],"cardiovascular":[28],"morbidity":[29],"mortality.":[31,240],"Emerging":[32],"data":[33],"suggest":[34],"a":[35,220,245],"direct":[36],"effect":[37],"erythropoietin":[39,213,254],"on":[40,74],"fibroblast":[41],"growth":[42],"factor":[43],"23":[44],"(FGF23),":[45],"elevated":[46,225],"which":[49,114],"have":[50],"been":[51],"adverse":[54],"outcomes.":[55],"We":[56],"investigate":[57],"effects":[58],"in":[62,83,168,244,258],"both":[65,102],"disease":[72,109],"focusing":[73],"FGF23.":[75],"Methods":[76],"Results":[78],"the":[80,127,183,250],"EPOCARES":[81],"(Erythropoietin":[82],"CardioRenal":[84],"Syndrome)":[85],"study,":[86],"we":[87],"randomized":[88,246],"56":[89],"anemic":[90],"(median":[92],"age":[93],"74":[94],"[interquartile":[95],"range":[96],"69-80]":[97],"years,":[98,191],"66%":[99],"male)":[100],"into":[110],"3":[111],"groups,":[112],"2":[115],"received":[116],"epoetin":[117],"beta":[118],"50":[119,124,143,153,223],"IU/kg":[120],"per":[121],"week":[122],"for":[123,188],"weeks,":[125,224],"third":[128],"group":[129],"served":[130],"as":[131,180],"control.":[132],"Measurements":[133],"were":[134,146,196],"performed":[135],"at":[136,230],"baseline":[137,192],"after":[139],"2,":[140],"26,":[141],"weeks.":[144],"Data":[145],"analyzed":[147],"using":[148],"linear":[149],"mixed-model":[150],"analysis.":[151],"After":[152],"weeks":[154],"agent":[157],"treatment,":[158],"hematocrit":[159],"increased.":[163],"Similarly,":[164],"C-terminal":[165,193,215],"FGF23":[166,172,194,216,256],"levels,":[167,173],"contrast":[169],"to":[170,177],"intact":[171],"rose":[174],"significantly":[175,233],"due":[176],"compared":[181],"controls.":[184],"During":[185],"median":[186],"follow-up":[187],"5.7":[189],"(2.0-5.7)":[190],"independently":[197],"mortality":[203],"(hazard":[204],"ratio":[205],"2.20;":[206],"95%":[207],"CI,":[208],"1.35-3.59;":[209],"P=0.002).":[210],"Conclusions":[211],"Exogenous":[212],"increases":[214],"markedly":[218],"over":[219],"period":[221],"which,":[228],"even":[229],"baseline,":[231],"are":[232],"The":[241],"current":[242],"results,":[243],"trial":[247],"setting,":[248],"underline":[249],"strong":[251],"relationship":[252],"between":[253],"physiology":[257],"disease.":[267],"Clinical":[268],"Trial":[269],"Registration":[270],"URL:":[271],"http://www.clinicaltrials.gov.":[272],"Unique":[273],"identifier:":[274],"NCT00356733.":[275]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3}],"updated_date":"2026-10-13T10:08:12.033832","created_date":"2025-10-10T00:00:00"}