{"id":"https://openalex.org/W2967740920","doi":"https://doi.org/10.1055/s-0039-1695549","title":"Lernkurve der tubul\u00e4ren \u00d6sophagus-ESD (T-ESD) zur Behandlung von Fr\u00fchkarzinomen mit waterjet-assistierten ESD-Messern in einem 2 Stufen Model. Eine randomisierte, kontrollierte Studie","display_name":"Lernkurve der tubul\u00e4ren \u00d6sophagus-ESD (T-ESD) zur Behandlung von Fr\u00fchkarzinomen mit waterjet-assistierten ESD-Messern in einem 2 Stufen Model. Eine randomisierte, kontrollierte Studie","publication_year":2019,"publication_date":"2019-08-13","ids":{"openalex":"https://openalex.org/W2967740920","doi":"https://doi.org/10.1055/s-0039-1695549","mag":"2967740920"},"language":"de","primary_location":{"id":"doi:10.1055/s-0039-1695549","doi":"https://doi.org/10.1055/s-0039-1695549","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-0039-1695549","pdf_url":null,"source":{"id":"https://openalex.org/S189922908","display_name":"Zeitschrift f\u00fcr Gastroenterologie","issn_l":"0044-2771","issn":["0044-2771","1439-7803"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift f\u00fcr Gastroenterologie","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://resolver.sub.uni-goettingen.de/purl?gro-2/157422","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015513295","display_name":"Edris Wedi","orcid":"https://orcid.org/0000-0002-6593-8636","observed_orcids":["https://orcid.org/0000-0002-6593-8636"]},"institutions":[{"id":"https://openalex.org/I4210116730","display_name":"Universit\u00e4tsmedizin G\u00f6ttingen","ror":"https://ror.org/021ft0n22","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210116730"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"E Wedi","raw_affiliation_strings":["Klinik f\u00fcr Gastroenterologie und gastrointestinale Onkologie der Universit\u00e4tsmedizin G\u00f6ttingen, G\u00f6ttingen, Deutschland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Klinik f\u00fcr Gastroenterologie und gastrointestinale Onkologie der Universit\u00e4tsmedizin G\u00f6ttingen, G\u00f6ttingen, Deutschland","institution_ids":["https://openalex.org/I4210116730"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037932490","display_name":"Carlo Felix Maria Jung","orcid":"https://orcid.org/0000-0002-8108-7173","observed_orcids":["https://orcid.org/0000-0002-8108-7173"]},"institutions":[{"id":"https://openalex.org/I4210116730","display_name":"Universit\u00e4tsmedizin G\u00f6ttingen","ror":"https://ror.org/021ft0n22","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210116730"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"CFM Jung","raw_affiliation_strings":["Klinik f\u00fcr Gastroenterologie und gastrointestinale Onkologie der Universit\u00e4tsmedizin G\u00f6ttingen, G\u00f6ttingen, Deutschland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Klinik f\u00fcr Gastroenterologie und gastrointestinale Onkologie der Universit\u00e4tsmedizin G\u00f6ttingen, G\u00f6ttingen, Deutschland","institution_ids":["https://openalex.org/I4210116730"]}]},{"author_position":"middle","author":{"id":null,"display_name":"C Fischer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210116730","display_name":"Universit\u00e4tsmedizin G\u00f6ttingen","ror":"https://ror.org/021ft0n22","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210116730"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"C Fischer","raw_affiliation_strings":["Klinik f\u00fcr Augenheilkunde der Universit\u00e4tsmedizin G\u00f6ttingen, G\u00f6ttingen, Deutschland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Klinik f\u00fcr Augenheilkunde der Universit\u00e4tsmedizin G\u00f6ttingen, G\u00f6ttingen, Deutschland","institution_ids":["https://openalex.org/I4210116730"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043618914","display_name":"K Ritter","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K Ritter","raw_affiliation_strings":["G-MEA General Medical Workshop Association, Jbeil, Byblos, Old Souk, Jbeil, Libanon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"G-MEA General Medical Workshop Association, Jbeil, Byblos, Old Souk, Jbeil, Libanon","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060589624","display_name":"Richard Friedemann Knoop","orcid":"https://orcid.org/0000-0002-2702-354X","observed_orcids":["https://orcid.org/0000-0002-2702-354X"]},"institutions":[{"id":"https://openalex.org/I4210116730","display_name":"Universit\u00e4tsmedizin G\u00f6ttingen","ror":"https://ror.org/021ft0n22","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210116730"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"R Knoop","raw_affiliation_strings":["Klinik f\u00fcr Gastroenterologie und gastrointestinale Onkologie der Universit\u00e4tsmedizin G\u00f6ttingen, G\u00f6ttingen, Deutschland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Klinik f\u00fcr Gastroenterologie und gastrointestinale Onkologie der Universit\u00e4tsmedizin G\u00f6ttingen, G\u00f6ttingen, Deutschland","institution_ids":["https://openalex.org/I4210116730"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046422102","display_name":"Volker Ellenrieder","orcid":"https://orcid.org/0000-0001-9981-8571","observed_orcids":["https://orcid.org/0000-0001-9981-8571"]},"institutions":[{"id":"https://openalex.org/I4210116730","display_name":"Universit\u00e4tsmedizin G\u00f6ttingen","ror":"https://ror.org/021ft0n22","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210116730"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"V Ellenrieder","raw_affiliation_strings":["Klinik f\u00fcr Gastroenterologie und gastrointestinale Onkologie der Universit\u00e4tsmedizin G\u00f6ttingen, G\u00f6ttingen, Deutschland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Klinik f\u00fcr Gastroenterologie und gastrointestinale Onkologie der Universit\u00e4tsmedizin G\u00f6ttingen, G\u00f6ttingen, Deutschland","institution_ids":["https://openalex.org/I4210116730"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047915793","display_name":"Juergen H. Hochberger","orcid":"https://orcid.org/0000-0001-5522-1271","observed_orcids":["https://orcid.org/0000-0001-5522-1271"]},"institutions":[{"id":"https://openalex.org/I4210152015","display_name":"Klinikum im Friedrichshain","ror":"https://ror.org/03zzvtn22","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210152015"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"J Hochberger","raw_affiliation_strings":["Vivantes Klinikum im Friedrichshain, Abteilung f\u00fcr Gastroenterologie, gastrointestinale Onkologie und Interventionelle Endoskopie, Berlin, Deutschland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vivantes Klinikum im Friedrichshain, Abteilung f\u00fcr Gastroenterologie, gastrointestinale Onkologie und Interventionelle Endoskopie, Berlin, Deutschland","institution_ids":["https://openalex.org/I4210152015"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111204584","display_name":"P K\u00f6hler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1310048521","display_name":"Friedrich-Loeffler-Institut","ror":"https://ror.org/025fw7a54","country_code":"DE","type":"government","lineage":["https://openalex.org/I1310048521","https://openalex.org/I2801963157"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"P K\u00f6hler","raw_affiliation_strings":["Friedrich-Loeffler-Institut (FLI) Bundesforschungsinstitut f\u00fcr Tiergesundheit, Mariensee, Deutschland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Friedrich-Loeffler-Institut (FLI) Bundesforschungsinstitut f\u00fcr Tiergesundheit, Mariensee, Deutschland","institution_ids":["https://openalex.org/I1310048521"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":0.9603999853134155,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":0.9603999853134155,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":0.029600000008940697,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11658","display_name":"Esophageal and GI Pathology","score":0.004900000058114529,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/learning-curve","display_name":"learning curve","score":0.9430000185966492},{"id":"https://openalex.org/keywords/en-bloc-resection","display_name":"en bloc resection","score":0.8709999918937683},{"id":"https://openalex.org/keywords/microperforation","display_name":"microperforation","score":0.7369999885559082},{"id":"https://openalex.org/keywords/resection-speed","display_name":"resection speed","score":0.527999997138977},{"id":"https://openalex.org/keywords/ex-vivo-model","display_name":"ex vivo model","score":0.5789999961853027},{"id":"https://openalex.org/keywords/animal-models","display_name":"animal models","score":0.7540000081062317},{"id":"https://openalex.org/keywords/en-bloc-resection-rate","display_name":"en bloc resection rate","score":0.46399998664855957},{"id":"https://openalex.org/keywords/esophageal-cancer-treatment","display_name":"esophageal cancer treatment","score":0.3869999945163727},{"id":"https://openalex.org/keywords/endoscopic-resection-safety","display_name":"endoscopic resection safety","score":0.3630000054836273}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5367444753646851},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.501288652420044}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1055/s-0039-1695549","doi":"https://doi.org/10.1055/s-0039-1695549","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-0039-1695549","pdf_url":null,"source":{"id":"https://openalex.org/S189922908","display_name":"Zeitschrift f\u00fcr Gastroenterologie","issn_l":"0044-2771","issn":["0044-2771","1439-7803"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift f\u00fcr Gastroenterologie","raw_type":"proceedings-article"},{"id":"pmh:oai:publications.goettingen-research-online.de:2/158907","doi":null,"is_oa":true,"landing_page_url":"https://resolver.sub.uni-goettingen.de/purl?gro-2/157422","pdf_url":null,"source":{"id":"https://openalex.org/S4306401634","display_name":"GoeScholar  The Publication Server of the Georg-August-Universit\u00e4t G\u00f6ttingen (Georg-August-Universit\u00e4t G\u00f6ttingen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210122495","host_organization_name":"Asklepios Klinik St. Georg","host_organization_lineage":["https://openalex.org/I4210122495"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/conferenceObject"},{"id":"pmh:oai:www.openagrar.de:openagrar_mods_00050722","doi":null,"is_oa":false,"landing_page_url":"https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0039-1695549","pdf_url":null,"source":{"id":"https://openalex.org/S7407055137","display_name":"OpenAgrar","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"abstract"}],"best_oa_location":{"id":"pmh:oai:publications.goettingen-research-online.de:2/158907","doi":null,"is_oa":true,"landing_page_url":"https://resolver.sub.uni-goettingen.de/purl?gro-2/157422","pdf_url":null,"source":{"id":"https://openalex.org/S4306401634","display_name":"GoeScholar  The Publication Server of the Georg-August-Universit\u00e4t G\u00f6ttingen (Georg-August-Universit\u00e4t G\u00f6ttingen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210122495","host_organization_name":"Asklepios Klinik St. Georg","host_organization_lineage":["https://openalex.org/I4210122495"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/conferenceObject"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4416643210","https://openalex.org/W4414049330","https://openalex.org/W1998504084","https://openalex.org/W2358039913","https://openalex.org/W2564005955","https://openalex.org/W7163907546","https://openalex.org/W2327670783","https://openalex.org/W2322953189","https://openalex.org/W2506735516","https://openalex.org/W2320802252"],"abstract_inverted_index":{"Einleitung:":[0],"Die":[1,107,200,246,266],"Endoskopische":[2],"Submukosa":[3],"Dissektion":[4],"(ESD)":[5],"wurde":[6],"Ende":[7],"der":[8,25,45,59,61,152,158,177,194,230,284,306],"1990er":[9],"Jahre":[10],"in":[11,89,112,183,193],"Japan":[12],"zur":[13,72,304],"\u201een-bloc\u201c":[14],"Resektion":[15,151],"von":[16,103],"fl\u00e4chigen":[17],"Magenkarzinomen":[18],"entwickelt.":[19],"Bisheriges":[20],"Hinderniss":[21],"f\u00fcr":[22],"die":[23,30,43,54,242,339],"Verbreitung":[24],"ESD":[26,47,307],"im":[27,49,164,308,320,327],"\u00d6sophagus":[28,50],"ist":[29],"sehr":[31],"anspruchsvolle":[32],"Technik":[33,340],"mit":[34,74,100,235],"einer":[35,101],"langen":[36],"Lernkurve.":[37],"Ziel":[38],"dieser":[39],"Studie":[40,71],"war":[41],"es,":[42],"Einsatzm\u00f6glichkeiten":[44],"tubul\u00e4ren":[46],"(T-ESD)":[48],"zu":[51,63,147],"untersuchen":[52],"und":[53,56,81,92,134,206,256,276,287,294,326],"Sicherheit":[55],"Effektivit\u00e4t":[57],"hinsichtlich":[58],"Lernkurve":[60,226],"Resektionstechnik":[62],"evaluieren.":[64],"Methodik:":[65],"Wir":[66],"f\u00fchrten":[67],"eine":[68,149,189,225],"prospektive,":[69],"randomisierte":[70],"T-ESD":[73],"einem":[75,82,90,318],"Flush":[76,119],"Knife":[77,84,120,125],"(Fujinon,":[78],"Fujifilm,":[79],"Japan)":[80],"Hybrid":[83,124],"(I-type,":[85],"Erbe":[86],"T\u00fcbingen,":[87],"Germany)":[88],"ex-vivo":[91,133,165,324],"in-vivo":[93,331],"Modell":[94],"durch.":[95],"Insgesamt":[96],"wurden":[97,111,130,161,289],"20":[98,144],"T-ESDs":[99,132,137,145],"L\u00e4nge":[102],"5":[104],"cm":[105],"durchgef\u00fchrt.":[106,140,167],"standardisierten,":[108],"vormarkierten":[109],"L\u00e4sionen":[110,154],"2":[113,313],"Messer-Gruppen":[114],"randomisiert":[115],"(":[116],"Gruppe":[117,122],"1:":[118],"(FK),":[121],"2:":[123],"(HK)).":[126],"F\u00fcr":[127],"jedes":[128],"ESD-Messer":[129],"7":[131,261],"jeweils":[135],"3":[136],"am":[138,180,323,330,341],"Gro\u00dftiermodel":[139],"Ergebnis:":[141],"Bei":[142,221,283],"allen":[143],"konnte":[146,224,233],"100%":[148],"en-bloc":[150],"artifiziellen":[153],"erreicht":[155],"werden.":[156,228,245],"In":[157,176],"1.":[159],"Phase":[160],"14/20":[162],"ESDs":[163],"Model":[166,325,332],"Hier":[168],"traten":[169,182],"2/20":[170],"(10%)":[171],"Mikroperforationen":[172],"auf":[173],"(1xHK,":[174],"1xFK).":[175],"2.":[178],"Versuchsphase":[179],"Tiermodel":[181],"beiden":[184,222],"Gruppen":[185],"keine":[186,290],"Perforationen":[187],"auf,":[188],"arterielle":[190],"Blutung":[191],"jedoch":[192],"HK":[195,207,237,251,271,293],"Gruppe,":[196],"welche":[197],"koaguliert":[198],"wurde.":[199],"mittlere":[201],"Resektionsgeschwindigkeit":[202],"(MRG)":[203],"beim":[204],"FK":[205,241,258,278,295],"betrug":[208,249,269],"40,0":[209],"\u00b1":[210,214,253,260,273,280],"11,10":[211],"vs.":[212],"55,3":[213],"24,11":[215],"min":[216,255,262,275],"(p":[217,263],"=":[218,264],"0,085;":[219],"t-Test).":[220],"Messern":[223],"dokumentiert":[227],"Nach":[229],"3.":[231],"T-ESD,":[232],"sowohl":[234],"dem":[236,240],"als":[238],"auch":[239],"ESD-Zeit":[243],"verbessert":[244],"MRG":[247,267],"(ex-vivo)":[248],"bei":[250,257,270,277],"33,5":[252],"2,5":[254],"37":[259],"0,3734).":[265],"(in-vivo)":[268],"61,0":[272],"28,0":[274],"33,0":[279],"7,87":[281],"min.":[282],"Markierungs-,":[285],"Injektions-":[286],"Inzisionszeit":[288],"Unterschiede":[291],"zwischen":[292],"dokumentiert.":[296],"Schlussfolgerung:":[297],"Bislang":[298],"gibt":[299],"es":[300],"keinen":[301],"strukturierten":[302],"Ausbildungsplan":[303],"Erlernung":[305],"\u00d6sophagus.":[309],"Das":[310],"hier":[311],"untersuchte":[312],"Stufen":[314],"Model,":[315],"bestehend":[316],"aus":[317],"Training":[319],"ersten":[321],"Schritt":[322,329],"zweiten":[328],"k\u00f6nnte":[333],"ein":[334],"sinnvolles":[335],"Lernkonzept":[336],"sein,":[337],"bevor":[338],"Patienten":[342],"angewandt":[343],"wird.":[344]},"counts_by_year":[],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2019-08-22T00:00:00"}