{"id":"https://openalex.org/W2967561541","doi":"https://doi.org/10.1093/gerona/glz180","title":"Associations of Brain Pathology Cognitive and Physical Markers With Age in Cognitively Normal Individuals Aged 60\u2013102 Years","display_name":"Associations of Brain Pathology Cognitive and Physical Markers With Age in Cognitively Normal Individuals Aged 60\u2013102 Years","publication_year":2019,"publication_date":"2019-08-14","ids":{"openalex":"https://openalex.org/W2967561541","doi":"https://doi.org/10.1093/gerona/glz180","mag":"2967561541","pmid":"https://pubmed.ncbi.nlm.nih.gov/31411322"},"language":"en","primary_location":{"id":"doi:10.1093/gerona/glz180","doi":"https://doi.org/10.1093/gerona/glz180","is_oa":true,"landing_page_url":"https://doi.org/10.1093/gerona/glz180","pdf_url":"https://academic.oup.com/biomedgerontology/article-pdf/75/9/1609/33753846/glz180.pdf","source":{"id":"https://openalex.org/S969433497","display_name":"The Journals of Gerontology Series A","issn_l":"1079-5006","issn":["1079-5006","1758-535X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journals of Gerontology: Series A","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/biomedgerontology/article-pdf/75/9/1609/33753846/glz180.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062695485","display_name":"Nienke Legdeur","orcid":"https://orcid.org/0000-0002-0646-934X","observed_orcids":["https://orcid.org/0000-0002-0646-934X"]},"institutions":[{"id":"https://openalex.org/I4210108594","display_name":"Amsterdam Neuroscience","ror":"https://ror.org/01x2d9f70","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210108594"]},{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]},{"id":"https://openalex.org/I911458345","display_name":"Amsterdam UMC Location Vrije Universiteit Amsterdam","ror":"https://ror.org/00q6h8f30","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833","https://openalex.org/I911458345"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Nienke Legdeur","raw_affiliation_strings":["Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210108594","https://openalex.org/I4210151833","https://openalex.org/I865915315","https://openalex.org/I911458345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030923361","display_name":"Betty Marije Tijms","orcid":"https://orcid.org/0000-0002-2612-1797","observed_orcids":["https://orcid.org/0000-0002-2612-1797"]},"institutions":[{"id":"https://openalex.org/I4210108594","display_name":"Amsterdam Neuroscience","ror":"https://ror.org/01x2d9f70","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210108594"]},{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]},{"id":"https://openalex.org/I911458345","display_name":"Amsterdam UMC Location Vrije Universiteit Amsterdam","ror":"https://ror.org/00q6h8f30","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833","https://openalex.org/I911458345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Betty M Tijms","raw_affiliation_strings":["Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210108594","https://openalex.org/I4210151833","https://openalex.org/I865915315","https://openalex.org/I911458345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052345056","display_name":"Elles Konijnenberg","orcid":"https://orcid.org/0000-0002-2962-2941","observed_orcids":["https://orcid.org/0000-0002-2962-2941"]},"institutions":[{"id":"https://openalex.org/I4210108594","display_name":"Amsterdam Neuroscience","ror":"https://ror.org/01x2d9f70","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210108594"]},{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]},{"id":"https://openalex.org/I911458345","display_name":"Amsterdam UMC Location Vrije Universiteit Amsterdam","ror":"https://ror.org/00q6h8f30","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833","https://openalex.org/I911458345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Elles Konijnenberg","raw_affiliation_strings":["Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210108594","https://openalex.org/I4210151833","https://openalex.org/I865915315","https://openalex.org/I911458345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050164405","display_name":"Anouk den Braber","orcid":"https://orcid.org/0000-0002-3377-2627","observed_orcids":["https://orcid.org/0000-0002-3377-2627"]},"institutions":[{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Anouk den Braber","raw_affiliation_strings":["Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I865915315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079993632","display_name":"Mara ten Kate","orcid":"https://orcid.org/0000-0002-8290-8543","observed_orcids":["https://orcid.org/0000-0002-8290-8543","https://orcid.org/0009-0000-0175-7847"]},"institutions":[{"id":"https://openalex.org/I4210108594","display_name":"Amsterdam Neuroscience","ror":"https://ror.org/01x2d9f70","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210108594"]},{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]},{"id":"https://openalex.org/I911458345","display_name":"Amsterdam UMC Location Vrije Universiteit Amsterdam","ror":"https://ror.org/00q6h8f30","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833","https://openalex.org/I911458345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Mara ten Kate","raw_affiliation_strings":["Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands","Department of Radiology and Nuclear Medicine, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210108594","https://openalex.org/I4210151833","https://openalex.org/I865915315","https://openalex.org/I911458345"]},{"raw_affiliation_string":"Department of Radiology and Nuclear Medicine, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210108594","https://openalex.org/I4210151833","https://openalex.org/I865915315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044422433","display_name":"Carole H. Sudre","orcid":"https://orcid.org/0000-0001-5753-428X","observed_orcids":["https://orcid.org/0000-0001-5753-428X"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I4405260083","display_name":"UCL Queen Square Institute of Neurology","ror":"https://ror.org/0370htr03","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Carole H Sudre","raw_affiliation_strings":["Dementia Research Centre, Institute of Neurology, University College London, London, UK","Department of Medical Physics and Biomedical Engineering, University College London, London, UK","School of Biomedical Engineering and Imaging Sciences, King\u2019s College London, London, UK","School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dementia Research Centre, Institute of Neurology, University College London, London, UK","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"raw_affiliation_string":"Department of Medical Physics and Biomedical Engineering, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"School of Biomedical Engineering and Imaging Sciences, King\u2019s College London, London, UK","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091497341","display_name":"Jori Tomassen","orcid":"https://orcid.org/0000-0003-2098-3633","observed_orcids":["https://orcid.org/0000-0003-2098-3633"]},"institutions":[{"id":"https://openalex.org/I4210108594","display_name":"Amsterdam Neuroscience","ror":"https://ror.org/01x2d9f70","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210108594"]},{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]},{"id":"https://openalex.org/I911458345","display_name":"Amsterdam UMC Location Vrije Universiteit Amsterdam","ror":"https://ror.org/00q6h8f30","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833","https://openalex.org/I911458345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Jori Tomassen","raw_affiliation_strings":["Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210108594","https://openalex.org/I4210151833","https://openalex.org/I865915315","https://openalex.org/I911458345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017073917","display_name":"Maryam Badissi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108594","display_name":"Amsterdam Neuroscience","ror":"https://ror.org/01x2d9f70","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210108594"]},{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]},{"id":"https://openalex.org/I911458345","display_name":"Amsterdam UMC Location Vrije Universiteit Amsterdam","ror":"https://ror.org/00q6h8f30","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833","https://openalex.org/I911458345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Maryam Badissi","raw_affiliation_strings":["Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210108594","https://openalex.org/I4210151833","https://openalex.org/I865915315","https://openalex.org/I911458345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023581145","display_name":"Maqsood M. Yaqub","orcid":"https://orcid.org/0000-0003-2122-740X","observed_orcids":["https://orcid.org/0000-0003-2122-740X","https://orcid.org/0000-0001-6738-2742"]},"institutions":[{"id":"https://openalex.org/I4210108594","display_name":"Amsterdam Neuroscience","ror":"https://ror.org/01x2d9f70","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210108594"]},{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Maqsood Yaqub","raw_affiliation_strings":["Department of Radiology and Nuclear Medicine, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology and Nuclear Medicine, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210108594","https://openalex.org/I4210151833","https://openalex.org/I865915315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064378373","display_name":"Frederik Barkhof","orcid":"https://orcid.org/0000-0003-3543-3706","observed_orcids":["https://orcid.org/0000-0003-3543-3706"]},"institutions":[{"id":"https://openalex.org/I4210108594","display_name":"Amsterdam Neuroscience","ror":"https://ror.org/01x2d9f70","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210108594"]},{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]}],"countries":["GB","NL"],"is_corresponding":false,"raw_author_name":"Frederik Barkhof","raw_affiliation_strings":["Department of Radiology and Nuclear Medicine, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands","European Society of Neuroradiology (ESNR), Institutes of Neurology and Healthcare Engineering, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology and Nuclear Medicine, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210108594","https://openalex.org/I4210151833","https://openalex.org/I865915315"]},{"raw_affiliation_string":"European Society of Neuroradiology (ESNR), Institutes of Neurology and Healthcare Engineering, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047564828","display_name":"Bart N.M. van Berckel","orcid":"https://orcid.org/0000-0003-1811-4383","observed_orcids":["https://orcid.org/0000-0003-1811-4383"]},"institutions":[{"id":"https://openalex.org/I4210108594","display_name":"Amsterdam Neuroscience","ror":"https://ror.org/01x2d9f70","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210108594"]},{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Bart N van Berckel","raw_affiliation_strings":["Department of Radiology and Nuclear Medicine, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology and Nuclear Medicine, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210108594","https://openalex.org/I4210151833","https://openalex.org/I865915315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079752137","display_name":"Dorret Irene Boomsma","orcid":"https://orcid.org/0000-0002-7099-7972","observed_orcids":["https://orcid.org/0000-0002-7099-7972"]},"institutions":[{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Dorret I Boomsma","raw_affiliation_strings":["Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I865915315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025870220","display_name":"Philip Scheltens","orcid":"https://orcid.org/0000-0002-1046-6408","observed_orcids":["https://orcid.org/0000-0002-1046-6408"]},"institutions":[{"id":"https://openalex.org/I4210108594","display_name":"Amsterdam Neuroscience","ror":"https://ror.org/01x2d9f70","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210108594"]},{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]},{"id":"https://openalex.org/I911458345","display_name":"Amsterdam UMC Location Vrije Universiteit Amsterdam","ror":"https://ror.org/00q6h8f30","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833","https://openalex.org/I911458345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Philip Scheltens","raw_affiliation_strings":["Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210108594","https://openalex.org/I4210151833","https://openalex.org/I865915315","https://openalex.org/I911458345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048283190","display_name":"Henne H. Holstege","orcid":"https://orcid.org/0000-0002-7688-3087","observed_orcids":["https://orcid.org/0000-0002-7688-3087"]},"institutions":[{"id":"https://openalex.org/I4210108594","display_name":"Amsterdam Neuroscience","ror":"https://ror.org/01x2d9f70","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210108594"]},{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]},{"id":"https://openalex.org/I911458345","display_name":"Amsterdam UMC Location Vrije Universiteit Amsterdam","ror":"https://ror.org/00q6h8f30","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833","https://openalex.org/I911458345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Henne Holstege","raw_affiliation_strings":["Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands","Department of Clinical Genetics, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210108594","https://openalex.org/I4210151833","https://openalex.org/I865915315","https://openalex.org/I911458345"]},{"raw_affiliation_string":"Department of Clinical Genetics, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210108594","https://openalex.org/I4210151833","https://openalex.org/I865915315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015665688","display_name":"Andrea Britta Maier","orcid":"https://orcid.org/0000-0001-7206-1724","observed_orcids":["https://orcid.org/0000-0001-7206-1724","https://orcid.org/0000-0002-5932-2026"]},"institutions":[{"id":"https://openalex.org/I1320473756","display_name":"The Royal Melbourne Hospital","ror":"https://ror.org/005bvs909","country_code":"AU","type":"funder","lineage":["https://openalex.org/I1320473756","https://openalex.org/I4210158168"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4405256582","display_name":"Amsterdam Movement Sciences","ror":"https://ror.org/04atb9h07","country_code":"NL","type":"funder","lineage":["https://openalex.org/I4405256582"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]}],"countries":["AU","NL"],"is_corresponding":false,"raw_author_name":"Andrea B Maier","raw_affiliation_strings":["Department of Human Movement Sciences, @AgeAmsterdam, Vrije Universiteit Amsterdam, Research Institute Amsterdam Movement Sciences, Amsterdam, The Netherlands","Department of Medicine and Aged Care, @AgeMelbourne, Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Human Movement Sciences, @AgeAmsterdam, Vrije Universiteit Amsterdam, Research Institute Amsterdam Movement Sciences, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4405256582","https://openalex.org/I865915315"]},{"raw_affiliation_string":"Department of Medicine and Aged Care, @AgeMelbourne, Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia","institution_ids":["https://openalex.org/I1320473756","https://openalex.org/I165779595"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029875703","display_name":"Pieter Jelle Visser","orcid":"https://orcid.org/0000-0001-8008-9727","observed_orcids":["https://orcid.org/0000-0001-8008-9727"]},"institutions":[{"id":"https://openalex.org/I34352273","display_name":"Maastricht University","ror":"https://ror.org/02jz4aj89","country_code":"NL","type":"education","lineage":["https://openalex.org/I34352273"]},{"id":"https://openalex.org/I4210108594","display_name":"Amsterdam Neuroscience","ror":"https://ror.org/01x2d9f70","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210108594"]},{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]},{"id":"https://openalex.org/I911458345","display_name":"Amsterdam UMC Location Vrije Universiteit Amsterdam","ror":"https://ror.org/00q6h8f30","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833","https://openalex.org/I911458345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Pieter Jelle Visser","raw_affiliation_strings":["Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands","Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210108594","https://openalex.org/I4210151833","https://openalex.org/I865915315","https://openalex.org/I911458345"]},{"raw_affiliation_string":"Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands","institution_ids":["https://openalex.org/I34352273"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5062695485"],"corresponding_institution_ids":["https://openalex.org/I4210108594","https://openalex.org/I4210151833","https://openalex.org/I865915315","https://openalex.org/I911458345"],"apc_list":{"value":4408,"currency":"USD","value_usd":4408},"apc_paid":{"value":4408,"currency":"USD","value_usd":4408},"fwci":0.7009,"has_fulltext":true,"cited_by_count":16,"citation_normalized_percentile":{"value":0.70781965,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"75","issue":"9","first_page":"1609","last_page":"1617"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11265","display_name":"Aging and Gerontology Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/3206","display_name":"Neuropsychology and Physiological Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11011","display_name":"Frailty in Older Adults","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuropathology","display_name":"neuropathology","score":0.9319999814033508},{"id":"https://openalex.org/keywords/cognitive-aging","display_name":"cognitive aging","score":0.7450000047683716},{"id":"https://openalex.org/keywords/physical-aging","display_name":"physical aging","score":0.7950000166893005},{"id":"https://openalex.org/keywords/cognitive-markers","display_name":"cognitive markers","score":0.5680000185966492},{"id":"https://openalex.org/keywords/handgrip-strength","display_name":"grip strength","score":0.7649999856948853},{"id":"https://openalex.org/keywords/digit-symbol-substitution-test","display_name":"Digit Symbol Substitution Test","score":0.9070000052452087},{"id":"https://openalex.org/keywords/hippocampal-volume","display_name":"hippocampal volume","score":0.9810000061988831},{"id":"https://openalex.org/keywords/amyloid-fibril-formation","display_name":"amyloid fibril formation","score":0.9620000123977661},{"id":"https://openalex.org/keywords/muscle-mass","display_name":"muscle mass","score":0.7929999828338623},{"id":"https://openalex.org/keywords/mini-mental-state-examination","display_name":"Mini-Mental State Examination","score":0.5690000057220459},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.6940000057220459},{"id":"https://openalex.org/keywords/educational-attainment","display_name":"educational attainment","score":0.800000011920929},{"id":"https://openalex.org/keywords/cognitively-normal-older-adults","display_name":"cognitively normal older adults","score":0.7879999876022339}],"concepts":[{"id":"https://openalex.org/C53084192","wikidata":"https://www.wikidata.org/wiki/Q1485121","display_name":"Gee","level":3,"score":0.7315523624420166},{"id":"https://openalex.org/C2777965283","wikidata":"https://www.wikidata.org/wiki/Q5275755","display_name":"Digit symbol substitution test","level":4,"score":0.720606803894043},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.633771538734436},{"id":"https://openalex.org/C27403532","wikidata":"https://www.wikidata.org/wiki/Q5532474","display_name":"Generalized estimating equation","level":2,"score":0.6060048937797546},{"id":"https://openalex.org/C122048520","wikidata":"https://www.wikidata.org/wiki/Q2913954","display_name":"Percentile","level":2,"score":0.5279238224029541},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.47980859875679016},{"id":"https://openalex.org/C142052008","wikidata":"https://www.wikidata.org/wiki/Q954027","display_name":"Cross-sectional study","level":2,"score":0.4489153027534485},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.4416767656803131},{"id":"https://openalex.org/C6057870","wikidata":"https://www.wikidata.org/wiki/Q5141248","display_name":"Cognitive test","level":3,"score":0.4126894176006317},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38412874937057495},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.37484121322631836},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3489874005317688},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.33085644245147705},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.3306615948677063},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.12735027074813843},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.0},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000066492","descriptor_name":"Cognitive Aging","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D000066492","descriptor_name":"Cognitive Aging","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D000066492","descriptor_name":"Cognitive Aging","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D000073216","descriptor_name":"Mental Status and Dementia Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000073216","descriptor_name":"Mental Status and Dementia Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000073216","descriptor_name":"Mental Status and Dementia Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004522","descriptor_name":"Educational Status","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004522","descriptor_name":"Educational Status","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004522","descriptor_name":"Educational Status","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016229","descriptor_name":"Amyloid beta-Peptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016229","descriptor_name":"Amyloid beta-Peptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016229","descriptor_name":"Amyloid beta-Peptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018737","descriptor_name":"Hand Strength","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018737","descriptor_name":"Hand Strength","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018737","descriptor_name":"Hand Strength","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":12,"locations":[{"id":"doi:10.1093/gerona/glz180","doi":"https://doi.org/10.1093/gerona/glz180","is_oa":true,"landing_page_url":"https://doi.org/10.1093/gerona/glz180","pdf_url":"https://academic.oup.com/biomedgerontology/article-pdf/75/9/1609/33753846/glz180.pdf","source":{"id":"https://openalex.org/S969433497","display_name":"The Journals of Gerontology Series A","issn_l":"1079-5006","issn":["1079-5006","1758-535X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journals of Gerontology: Series A","raw_type":"journal-article"},{"id":"pmid:31411322","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31411322","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The journals of gerontology. Series A, Biological sciences and medical sciences","raw_type":"Journal Article"},{"id":"pmh:oai:cris.maastrichtuniversity.nl:openaire/750ceb51-b3c5-46a6-9d8e-23df86c1bbdc","doi":null,"is_oa":true,"landing_page_url":"https://cris.maastrichtuniversity.nl/en/publications/750ceb51-b3c5-46a6-9d8e-23df86c1bbdc","pdf_url":null,"source":{"id":"https://openalex.org/S4306402616","display_name":"Research Publications (Maastricht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I34352273","host_organization_name":"Maastricht University","host_organization_lineage":["https://openalex.org/I34352273"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Legdeur, N, Tijms, B M, Konijnenberg, E, den Braber, A, Ten Kate, M, Sudre, C H, Tomassen, J, Badissi, M, Yaqub, M, Barkhof, F, van Berckel, B N, Boomsma, D I, Scheltens, P, Holstege, H, Maier, A B & Visser, P J 2020, 'Associations of brain pathology, cognitive and physical markers with age in cognitively normal individuals aged 60-102 years', Journals of Gerontology Series A-Biological Sciences and Medical Sciences, vol. 75, no. 9, pp. 1609-1617. https://doi.org/10.1093/gerona/glz180","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:jupiter.its.unimelb.edu.au:11343/251430","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/11343/251430","pdf_url":"http://hdl.handle.net/11343/251430","source":{"id":"https://openalex.org/S4377196259","display_name":"Minerva Access (University of Melbourne)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I165779595","host_organization_name":"The University of Melbourne","host_organization_lineage":["https://openalex.org/I165779595"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal Article"},{"id":"pmh:oai:pure.amsterdamumc.nl:openaire/fded0ba3-1459-461a-a8d8-caaef0b83738","doi":null,"is_oa":true,"landing_page_url":"https://pure.amsterdamumc.nl/en/publications/fded0ba3-1459-461a-a8d8-caaef0b83738","pdf_url":"https://pure.amsterdamumc.nl/files/136322575/glz180.pdf","source":{"id":"https://openalex.org/S7407055222","display_name":"Pure Amsterdam UMC","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Legdeur, N, Tijms, B M, Konijnenberg, E, den Braber, A, ten Kate, M, Sudre, C H, Tomassen, J, Badissi, M, Yaqub, M, Barkhof, F, van Berckel, B N, Boomsma, D I, Scheltens, P, Holstege, H, Maier, A B & Visser, P J 2020, 'Associations of Brain Pathology Cognitive and Physical Markers With Age in Cognitively Normal Individuals Aged 60-102 Years', journals of gerontology. Series A, Biological sciences and medical sciences, vol. 75, no. 9, pp. 1609-1617. https://doi.org/10.1093/gerona/glz180","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7494041","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7494041","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Gerontol A Biol Sci Med Sci","raw_type":"Text"},{"id":"pmh:oai:scholarbank.nus.edu.sg:10635/234899","doi":null,"is_oa":false,"landing_page_url":"https://scholarbank.nus.edu.sg/handle/10635/234899","pdf_url":null,"source":{"id":"https://openalex.org/S7407052290","display_name":"National University of Singapore","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Elements","raw_type":"Article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:10082743","doi":null,"is_oa":false,"landing_page_url":"https://discovery.ucl.ac.uk/id/eprint/10082743/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The Journals of Gerontology: Series A , 75 (9) pp. 1609-1617. (2019)","raw_type":"Article"},{"id":"pmh:oai:research.vu.nl:openaire/397c6871-331d-41b4-9025-cbc63d81a889","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/1871.1/397c6871-331d-41b4-9025-cbc63d81a889","pdf_url":null,"source":{"id":"https://openalex.org/S4306401107","display_name":"VU Research Portal","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I865915315","host_organization_name":"Vrije Universiteit Amsterdam","host_organization_lineage":["https://openalex.org/I865915315"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Legdeur, N, Tijms, B M, Konijnenberg, E, den Braber, A, Ten Kate, M, Sudre, C H, Tomassen, J, Badissi, M, Yaqub, M, Barkhof, F, van Berckel, B N, Boomsma, D I, Scheltens, P, Holstege, H, Maier, A B & Visser, P J 2020, 'Associations of brain pathology, cognitive and physical markers with age in cognitively normal individuals aged 60-102 years', The journals of gerontology. Series A : Biological sciences and medical sciences, vol. 75, no. 9, pp. 1609-1617. https://doi.org/10.1093/gerona/glz180","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:um:oai:cris.maastrichtuniversity.nl:publications/750ceb51-b3c5-46a6-9d8e-23df86c1bbdc","doi":null,"is_oa":true,"landing_page_url":"https://cris.maastrichtuniversity.nl/en/publications/750ceb51-b3c5-46a6-9d8e-23df86c1bbdc","pdf_url":null,"source":{"id":"https://openalex.org/S4306402616","display_name":"Research Publications (Maastricht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I34352273","host_organization_name":"Maastricht University","host_organization_lineage":["https://openalex.org/I34352273"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journals of Gerontology Series A-Biological Sciences and Medical Sciences, 75(9), 1609 - 1617. Oxford University Press","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:vu:oai:research.vu.nl:publications/397c6871-331d-41b4-9025-cbc63d81a889","doi":null,"is_oa":true,"landing_page_url":"https://research.vu.nl/en/publications/397c6871-331d-41b4-9025-cbc63d81a889","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The journals of gerontology. Series A : Biological sciences and medical sciences, 75(9), 1609 - 1617. Oxford University Press","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:vumc:oai:pure.atira.dk:publications/83842a88-7530-4992-8fe9-f6608e6865d6","doi":null,"is_oa":true,"landing_page_url":"https://research.vumc.nl/en/publications/83842a88-7530-4992-8fe9-f6608e6865d6","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The journals of gerontology. Series A, Biological sciences and medical sciences, 75(9), 1609 - 1617. Oxford University Press","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1093/gerona/glz180","doi":"https://doi.org/10.1093/gerona/glz180","is_oa":true,"landing_page_url":"https://doi.org/10.1093/gerona/glz180","pdf_url":"https://academic.oup.com/biomedgerontology/article-pdf/75/9/1609/33753846/glz180.pdf","source":{"id":"https://openalex.org/S969433497","display_name":"The Journals of Gerontology Series A","issn_l":"1079-5006","issn":["1079-5006","1758-535X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journals of Gerontology: Series A","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"sustainable_development_goals_aurora":[{"display_name":"Quality education","id":"https://metadata.un.org/sdg/4","score":0.8700000047683716}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6382720711","display_name":null,"funder_award_id":"115372","funder_id":"https://openalex.org/F4320314178","funder_display_name":"European Federation of Pharmaceutical Industries and Associations"}],"funders":[{"id":"https://openalex.org/F4320314178","display_name":"European Federation of Pharmaceutical Industries and Associations","ror":"https://ror.org/00g1x4v36"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320325311","display_name":"University College London Hospitals NHS Foundation Trust","ror":"https://ror.org/042fqyp44"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2967561541.pdf","grobid_xml":"https://content.openalex.org/works/W2967561541.grobid-xml"},"referenced_works_count":55,"referenced_works":["https://openalex.org/W1971548649","https://openalex.org/W1988470975","https://openalex.org/W1989199273","https://openalex.org/W1991952617","https://openalex.org/W1992136850","https://openalex.org/W2004293194","https://openalex.org/W2004371621","https://openalex.org/W2031047184","https://openalex.org/W2038018468","https://openalex.org/W2039664444","https://openalex.org/W2042247941","https://openalex.org/W2062340864","https://openalex.org/W2064963539","https://openalex.org/W2067975928","https://openalex.org/W2074212320","https://openalex.org/W2074980270","https://openalex.org/W2077435037","https://openalex.org/W2077849930","https://openalex.org/W2091585384","https://openalex.org/W2091753181","https://openalex.org/W2096098781","https://openalex.org/W2102902846","https://openalex.org/W2103976905","https://openalex.org/W2104287008","https://openalex.org/W2107369063","https://openalex.org/W2110957605","https://openalex.org/W2119481903","https://openalex.org/W2124405724","https://openalex.org/W2124812490","https://openalex.org/W2127835340","https://openalex.org/W2133489234","https://openalex.org/W2134711807","https://openalex.org/W2135140141","https://openalex.org/W2158766477","https://openalex.org/W2161962285","https://openalex.org/W2168357345","https://openalex.org/W2493297632","https://openalex.org/W2529649944","https://openalex.org/W2582743722","https://openalex.org/W2585471097","https://openalex.org/W2768948569","https://openalex.org/W2787882567","https://openalex.org/W2803902280","https://openalex.org/W2810507529","https://openalex.org/W2886692233","https://openalex.org/W2888171838","https://openalex.org/W2897513125","https://openalex.org/W2897636790","https://openalex.org/W2897712355","https://openalex.org/W2902480995","https://openalex.org/W2904433573","https://openalex.org/W2950049542","https://openalex.org/W6748631114","https://openalex.org/W6756459161","https://openalex.org/W7075278555"],"related_works":["https://openalex.org/W2363926121","https://openalex.org/W2070243348","https://openalex.org/W1988971925","https://openalex.org/W1855024394","https://openalex.org/W2810368072","https://openalex.org/W188365466","https://openalex.org/W2169152159","https://openalex.org/W2063585734","https://openalex.org/W2203203921","https://openalex.org/W2084081473"],"abstract_inverted_index":{"The":[0,95,126],"prevalence":[1,96,129],"of":[2,33,84,97,130,139,154],"brain":[3,36,155],"pathologies":[4],"increases":[5],"with":[6,27,42,70,113,163],"age":[7,43,114],"and":[8,10,39,58,106,115,121,141,158],"cognitive":[9,38,157],"physical":[11,40,159],"functions":[12,41],"worsen":[13],"over":[14],"the":[15,31,54,62,74,78,101,110,124],"lifetime.":[16],"It":[17],"is":[18],"unclear":[19],"whether":[20],"these":[21],"processes":[22,160],"show":[23],"a":[24,71,148],"similar":[25],"increase":[26,112,127],"age.":[28,164],"We":[29,144],"studied":[30],"association":[32],"markers":[34,132,153],"for":[35],"pathology":[37,156],"in":[44,77,128,151],"288":[45],"cognitively":[46],"normal":[47],"individuals":[48],"aged":[49],"60-102":[50],"years":[51],"selected":[52],"from":[53],"cross-sectional":[55],"EMIF-AD":[56],"PreclinAD":[57],"90+":[59],"Study":[60],"at":[61],"Amsterdam":[63],"UMC.":[64],"An":[65],"abnormal":[66,85,98,116,131,162],"score":[67,72],"was":[68,87,133],"consistent":[69,149],"below":[73],"5th":[75],"percentile":[76],"60-":[79],"to":[80],"70-year-old":[81],"individuals.":[82],"Prevalence":[83],"scores":[86],"estimated":[88],"using":[89],"Generalized":[90],"Estimating":[91],"Equations":[92],"(GEE)":[93],"models.":[94],"handgrip":[99],"strength,":[100],"Digit":[102],"Symbol":[103],"Substitution":[104],"Test,":[105],"hippocampal":[107],"volume":[108],"showed":[109],"fastest":[111],"MMSE":[117],"score,":[118],"muscle":[119],"mass,":[120],"amyloid":[122,142],"aggregation":[123],"lowest.":[125],"partly":[134],"dependent":[135],"on":[136],"sex,":[137],"level":[138],"education,":[140],"aggregation.":[143],"did":[145],"not":[146],"find":[147],"pattern":[150],"which":[152],"became":[161]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}