{"id":"https://openalex.org/W2966487167","doi":null,"title":"The Anti-Inflammatory Benefit of Statins for Chronic Obstructive Pulmonary Disease (COPD): Review Article","display_name":"The Anti-Inflammatory Benefit of Statins for Chronic Obstructive Pulmonary Disease (COPD): Review Article","publication_year":2019,"publication_date":"2019-07-30","ids":{"openalex":"https://openalex.org/W2966487167","mag":"2966487167"},"language":"en","primary_location":{"id":"mag:2966487167","doi":null,"is_oa":true,"landing_page_url":"https://pji.ub.ac.id/index.php/pji/article/download/123/82","pdf_url":null,"source":{"id":"https://openalex.org/S4210217764","display_name":"Pharmaceutical Journal of Indonesia","issn_l":"2461-114X","issn":["2461-114X"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310314997","host_organization_name":"Brawijaya University","host_organization_lineage":["https://openalex.org/P4310314997"],"host_organization_lineage_names":["Brawijaya University"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Pharmaceutical Journal of Indonesia","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://pji.ub.ac.id/index.php/pji/article/download/123/82","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043801542","display_name":"Yunita Kristiana Dewi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205133468","display_name":"Universitas Airlangga","ror":"https://ror.org/04ctejd88","country_code":"ID","type":"education","lineage":["https://openalex.org/I205133468"]}],"countries":["ID"],"is_corresponding":true,"raw_author_name":"Yunita Kristiana Dewi","raw_affiliation_strings":["Master of Clinical Pharmacy Programme, Faculty of Pharmacy, University of Airlangga, Surabaya, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Master of Clinical Pharmacy Programme, Faculty of Pharmacy, University of Airlangga, Surabaya, Indonesia","institution_ids":["https://openalex.org/I205133468"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5043801542"],"corresponding_institution_ids":["https://openalex.org/I205133468"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"4","issue":"2","first_page":"99","last_page":"105"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10678","display_name":"Inflammatory mediators and NSAID effects","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/statins","display_name":"statins","score":0.8640000224113464},{"id":"https://openalex.org/keywords/chronic-obstructive-pulmonary-disease","display_name":"chronic obstructive pulmonary disease","score":1.0},{"id":"https://openalex.org/keywords/anti-inflammatory-activity","display_name":"anti-inflammatory activity","score":0.8799999952316284},{"id":"https://openalex.org/keywords/systemic-inflammation","display_name":"systemic inflammation","score":0.9909999966621399},{"id":"https://openalex.org/keywords/airflow-obstruction","display_name":"airflow obstruction","score":0.6230000257492065},{"id":"https://openalex.org/keywords/immunomodulation","display_name":"immunomodulation","score":0.7509999871253967},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.9049999713897705},{"id":"https://openalex.org/keywords/pharmacological-mechanisms","display_name":"pharmacological mechanisms","score":0.5950000286102295},{"id":"https://openalex.org/keywords/copd-treatment","display_name":"COPD treatment","score":0.6779999732971191}],"concepts":[{"id":"https://openalex.org/C2776780178","wikidata":"https://www.wikidata.org/wiki/Q199804","display_name":"COPD","level":2,"score":0.9100578427314758},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8860406875610352},{"id":"https://openalex.org/C2992779976","wikidata":"https://www.wikidata.org/wiki/Q3286546","display_name":"Pulmonary disease","level":2,"score":0.7241513133049011},{"id":"https://openalex.org/C2776839432","wikidata":"https://www.wikidata.org/wiki/Q954845","display_name":"Statin","level":2,"score":0.6130214333534241},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.5570552349090576},{"id":"https://openalex.org/C2776252253","wikidata":"https://www.wikidata.org/wiki/Q7663815","display_name":"Systemic inflammation","level":3,"score":0.5091411471366882},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.469772070646286},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.33618462085723877},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3246085047721863}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2966487167","doi":null,"is_oa":true,"landing_page_url":"https://pji.ub.ac.id/index.php/pji/article/download/123/82","pdf_url":null,"source":{"id":"https://openalex.org/S4210217764","display_name":"Pharmaceutical Journal of Indonesia","issn_l":"2461-114X","issn":["2461-114X"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310314997","host_organization_name":"Brawijaya University","host_organization_lineage":["https://openalex.org/P4310314997"],"host_organization_lineage_names":["Brawijaya University"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Pharmaceutical Journal of Indonesia","raw_type":null}],"best_oa_location":{"id":"mag:2966487167","doi":null,"is_oa":true,"landing_page_url":"https://pji.ub.ac.id/index.php/pji/article/download/123/82","pdf_url":null,"source":{"id":"https://openalex.org/S4210217764","display_name":"Pharmaceutical Journal of Indonesia","issn_l":"2461-114X","issn":["2461-114X"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310314997","host_organization_name":"Brawijaya University","host_organization_lineage":["https://openalex.org/P4310314997"],"host_organization_lineage_names":["Brawijaya University"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Pharmaceutical Journal of Indonesia","raw_type":null},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W387031605","https://openalex.org/W1525331105","https://openalex.org/W1907316344","https://openalex.org/W1975914758","https://openalex.org/W1980431670","https://openalex.org/W1993489169","https://openalex.org/W2006572302","https://openalex.org/W2031579146","https://openalex.org/W2059232148","https://openalex.org/W2082567765","https://openalex.org/W2087149852","https://openalex.org/W2107555017","https://openalex.org/W2127667687","https://openalex.org/W2127951128","https://openalex.org/W2138220081","https://openalex.org/W2142493198","https://openalex.org/W2146546690","https://openalex.org/W2155853522","https://openalex.org/W2401306489","https://openalex.org/W2406452535","https://openalex.org/W2746473595","https://openalex.org/W2762206464","https://openalex.org/W2793447600"],"related_works":["https://openalex.org/W7042662801","https://openalex.org/W2901626591","https://openalex.org/W7097965044","https://openalex.org/W2128848793","https://openalex.org/W2044204991","https://openalex.org/W2301124723","https://openalex.org/W2162485050","https://openalex.org/W3032654840","https://openalex.org/W2266710315","https://openalex.org/W2360260624"],"abstract_inverted_index":{"Chronic":[0],"Obstructive":[1],"Pulmonary":[2],"Disease":[3],"(COPD)":[6],"is":[7,42,83],"characterized":[8],"by":[9],"progressive,":[10],"minimally":[11],"reversible":[12],"airflow":[13],"limitation":[14],"and":[15,57],"systemic":[16],"inflammation.":[17],"Over":[18],"the":[19,29,64,86],"last":[20],"5":[21],"years,":[22],"there":[23],"have":[24,68],"been\u00a0":[25],"abundant":[26],"studies":[27],"proving":[28],"benefit":[30],"of":[31,51,62,66,80,89],"statin":[32,41,67],"in":[33,45,102],"COPD":[34,76],"as":[35,91,100],"an":[36],"anti-inflammatory":[37,92],"agent.":[38],"So":[39],"far,":[40],"mostly":[43],"utilized":[44],"cardiology":[46],"due":[47],"to":[48,70,75,84],"its":[49],"effects":[50,65],"cholesterol":[52],"reduction,":[53],"immune":[54],"system":[55],"modulation,":[56],"anti":[58],"oxidant.":[59],"In":[60],"point":[61],"fact,":[63],"proven":[69],"be":[71,98],"advantageous":[72],"when":[73],"administered":[74],"patients.":[77],"The":[78],"aim":[79],"this":[81],"review":[82],"examine":[85],"pharmacological":[87],"mechanism":[88],"statins":[90],"drugs":[93],"so":[94],"that":[95],"they":[96],"can":[97],"considered":[99],"therapy":[101],"COPD.":[103]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-08-13T00:00:00"}