{"id":"https://openalex.org/W2965943602","doi":"https://doi.org/10.1002/cncr.32416","title":"Diagnostic value of biopsy sampling in predicting histology in patients with diffuse malignant pleural mesothelioma","display_name":"Diagnostic value of biopsy sampling in predicting histology in patients with diffuse malignant pleural mesothelioma","publication_year":2019,"publication_date":"2019-08-07","ids":{"openalex":"https://openalex.org/W2965943602","doi":"https://doi.org/10.1002/cncr.32416","mag":"2965943602","pmid":"https://pubmed.ncbi.nlm.nih.gov/31390057","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7341068"},"language":"en","primary_location":{"id":"doi:10.1002/cncr.32416","doi":"https://doi.org/10.1002/cncr.32416","is_oa":false,"landing_page_url":"https://doi.org/10.1002/cncr.32416","pdf_url":null,"source":{"id":"https://openalex.org/S126033908","display_name":"Cancer","issn_l":"0008-543X","issn":["0008-543X","1045-7410","1097-0142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7341068","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089159833","display_name":"Lucian R. Chirieac","orcid":"https://orcid.org/0000-0002-4383-6938","observed_orcids":["https://orcid.org/0000-0002-4383-6938"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Lucian R. Chirieac","raw_affiliation_strings":["Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts"],"raw_orcid":"https://orcid.org/0000-0002-4383-6938","affiliations":[{"raw_affiliation_string":"Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039324896","display_name":"Yin Pun Hung","orcid":"https://orcid.org/0000-0002-8568-1591","observed_orcids":["https://orcid.org/0000-0002-8568-1591"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yin P. Hung","raw_affiliation_strings":["Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts"],"raw_orcid":"https://orcid.org/0000-0002-8568-1591","affiliations":[{"raw_affiliation_string":"Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010261217","display_name":"Wai Chin Foo","orcid":"https://orcid.org/0000-0002-0471-4911","observed_orcids":["https://orcid.org/0000-0002-0471-4911"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wai Chin Foo","raw_affiliation_strings":["Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101887913","display_name":"Matthias D. Hofer","orcid":"https://orcid.org/0000-0001-8393-2468","observed_orcids":["https://orcid.org/0000-0001-8393-2468"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]},{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthias D. Hofer","raw_affiliation_strings":["Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055688102","display_name":"Paul A. VanderLaan","orcid":"https://orcid.org/0000-0002-7234-5652","observed_orcids":["https://orcid.org/0000-0002-7234-5652"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul A. VanderLaan","raw_affiliation_strings":["Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","Division of Anatomic Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts"],"raw_orcid":"https://orcid.org/0000-0002-7234-5652","affiliations":[{"raw_affiliation_string":"Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Anatomic Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I1316535847","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036450155","display_name":"William G. Richards","orcid":"https://orcid.org/0000-0003-0990-8317","observed_orcids":["https://orcid.org/0000-0003-0990-8317"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William G. Richards","raw_affiliation_strings":["Department of Thoracic Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Thoracic Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109939587","display_name":"David J. Sugarbaker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David J. Sugarbaker","raw_affiliation_strings":["Department of Thoracic Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Thoracic Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102946061","display_name":"Raphael Bueno","orcid":"https://orcid.org/0000-0002-1258-8468","observed_orcids":["https://orcid.org/0000-0002-1258-8468"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Raphael Bueno","raw_affiliation_strings":["Department of Thoracic Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Thoracic Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5089159833"],"corresponding_institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"],"apc_list":{"value":4200,"currency":"USD","value_usd":4200},"apc_paid":null,"fwci":4.648,"has_fulltext":false,"cited_by_count":50,"citation_normalized_percentile":{"value":0.95641658,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"125","issue":"23","first_page":"4164","last_page":"4171"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11026","display_name":"Occupational and environmental lung diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11026","display_name":"Occupational and environmental lung diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12064","display_name":"Intraperitoneal and Appendiceal Malignancies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11356","display_name":"Pleural and Pulmonary Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diffuse-malignant-pleural-mesothelioma","display_name":"diffuse malignant pleural mesothelioma","score":0.9200000166893005},{"id":"https://openalex.org/keywords/biopsy-sampling","display_name":"biopsy sampling","score":0.7799999713897705},{"id":"https://openalex.org/keywords/histological-classification","display_name":"histological classification","score":0.890999972820282},{"id":"https://openalex.org/keywords/epithelioid-histology","display_name":"epithelioid histology","score":0.8759999871253967},{"id":"https://openalex.org/keywords/sarcomatoid-histology","display_name":"sarcomatoid histology","score":0.9990000128746033},{"id":"https://openalex.org/keywords/intratumor-heterogeneity","display_name":"intratumoral heterogeneity","score":0.9070000052452087},{"id":"https://openalex.org/keywords/core-needle-biopsy","display_name":"core needle biopsy","score":0.8100000023841858},{"id":"https://openalex.org/keywords/thoracoscopic-biopsy","display_name":"thoracoscopic biopsy","score":0.9959999918937683},{"id":"https://openalex.org/keywords/pleurectomy-decortication","display_name":"pleurectomy/decortication","score":0.9039999842643738},{"id":"https://openalex.org/keywords/extrapleural-pneumonectomy","display_name":"extrapleural pneumonectomy","score":0.9990000128746033},{"id":"https://openalex.org/keywords/histologic-concordance","display_name":"histologic concordance","score":0.7609999775886536},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.8389999866485596},{"id":"https://openalex.org/keywords/diagnostic-accuracy","display_name":"diagnostic accuracy","score":0.5189999938011169}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9268438816070557},{"id":"https://openalex.org/C57742111","wikidata":"https://www.wikidata.org/wiki/Q7168","display_name":"Histology","level":2,"score":0.661740779876709},{"id":"https://openalex.org/C2777407522","wikidata":"https://www.wikidata.org/wiki/Q1077603","display_name":"Mesothelioma","level":2,"score":0.6521620154380798},{"id":"https://openalex.org/C140779682","wikidata":"https://www.wikidata.org/wiki/Q210868","display_name":"Sampling (signal processing)","level":3,"score":0.6397298574447632},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.5872384309768677},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.47569191455841064},{"id":"https://openalex.org/C2776517811","wikidata":"https://www.wikidata.org/wiki/Q7204732","display_name":"Pleural disease","level":4,"score":0.4136800169944763},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4087311923503876},{"id":"https://openalex.org/C2776178081","wikidata":"https://www.wikidata.org/wiki/Q3286546","display_name":"Respiratory disease","level":3,"score":0.20081299543380737},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1479959487915039},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.09741231799125671},{"id":"https://openalex.org/C106131492","wikidata":"https://www.wikidata.org/wiki/Q3072260","display_name":"Filter (signal processing)","level":2,"score":0.0},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000086002","descriptor_name":"Mesothelioma, Malignant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008654","descriptor_name":"Mesothelioma","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D008654","descriptor_name":"Mesothelioma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008654","descriptor_name":"Mesothelioma","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1002/cncr.32416","doi":"https://doi.org/10.1002/cncr.32416","is_oa":false,"landing_page_url":"https://doi.org/10.1002/cncr.32416","pdf_url":null,"source":{"id":"https://openalex.org/S126033908","display_name":"Cancer","issn_l":"0008-543X","issn":["0008-543X","1045-7410","1097-0142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer","raw_type":"journal-article"},{"id":"pmid:31390057","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31390057","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7341068","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7341068","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Cancer","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7341068","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7341068","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Cancer","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G904921259","display_name":"Prospective Validation of Prognostic and Predictive Molecular tests in Mesothelioma","funder_award_id":"R01CA120528","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W67716143","https://openalex.org/W1766286185","https://openalex.org/W1836606828","https://openalex.org/W1930738953","https://openalex.org/W1968154700","https://openalex.org/W1976854607","https://openalex.org/W1977376622","https://openalex.org/W1997241984","https://openalex.org/W2009545853","https://openalex.org/W2013824371","https://openalex.org/W2026006116","https://openalex.org/W2027008029","https://openalex.org/W2027320543","https://openalex.org/W2028666445","https://openalex.org/W2043084228","https://openalex.org/W2051530367","https://openalex.org/W2058808716","https://openalex.org/W2062258674","https://openalex.org/W2076603991","https://openalex.org/W2081597702","https://openalex.org/W2095392215","https://openalex.org/W2114866480","https://openalex.org/W2131561057","https://openalex.org/W2137231880","https://openalex.org/W2158408253","https://openalex.org/W2168556230","https://openalex.org/W2395641640","https://openalex.org/W2481968169","https://openalex.org/W2502134830","https://openalex.org/W2743612849","https://openalex.org/W2801825617","https://openalex.org/W2889469922","https://openalex.org/W2917840530","https://openalex.org/W4239180165","https://openalex.org/W4239860756"],"related_works":["https://openalex.org/W3138938091","https://openalex.org/W2331713953","https://openalex.org/W2600367680","https://openalex.org/W2043084228","https://openalex.org/W2028666445","https://openalex.org/W2076603991","https://openalex.org/W2058808716","https://openalex.org/W2110934295","https://openalex.org/W4413117728","https://openalex.org/W6926847871"],"abstract_inverted_index":{"Background":[0],"The":[1,18,38,98,148],"classification":[2,257],"of":[3,26,34,42,80,102,178,255,262,270],"diffuse":[4,50,68],"malignant":[5,51,69,116],"mesothelioma":[6,52,70,117],"into":[7],"epithelioid,":[8,160],"biphasic,":[9,161],"and":[10,24,40,53,85,94,100,108,111,132,138,155,162,170],"sarcomatoid":[11,83,125,139,163,243],"types":[12],"is":[13,20,247],"based":[14],"on":[15,22],"histologic":[16,256],"patterns.":[17],"diagnosis":[19],"made":[21],"biopsies,":[23],"because":[25],"intratumoral":[27,251],"heterogeneity,":[28,252],"they":[29],"may":[30],"not":[31,230],"be":[32],"representative":[33],"the":[35,78,88,223,232,253,260,267],"entire":[36],"tumor.":[37],"number":[39,99,177,261],"volume":[41,101,202],"biopsies":[43,90,103,131,158,169,179,246],"needed":[44],"to":[45,240],"reach":[46],"diagnostic":[47,268],"accuracy":[48,254],"in":[49,130,141,222,231,245],"their":[54],"prognostic":[55],"value":[56,269],"remain":[57],"unclear.":[58],"Methods":[59],"This":[60],"study":[61],"examined":[62],"759":[63],"consecutive":[64],"patients":[65],"with":[66,106,159,174,199,259],"pleural":[67],"treated":[71],"by":[72,220,273],"pleurectomy/decortication":[73],"or":[74,92,127],"extrapleural":[75],"pneumonectomy":[76],"for":[77,157,183],"presence":[79],"epithelioid":[81,121,134,241],"and/or":[82],"histology":[84,221,244],"classified":[86,119],"both":[87],"presurgery":[89,274],"(core\u2010needle":[91],"thoracoscopic)":[93],"surgical":[95,142],"resection":[96,143,224],"specimens.":[97],"were":[104,152,172,196],"correlated":[105],"pre\u2010":[107],"postsurgery":[109],"histologies":[110,167,185],"overall":[112,215],"survival.":[113],"Results":[114],"Diffuse":[115],"was":[118,217],"as":[120,133],"(76%),":[122],"biphasic":[123,136],"(18%),":[124],"(5%),":[126],"indeterminate":[128],"(1%)":[129],"(64%),":[135],"(32%),":[137],"(4%)":[140],"specimens":[144],"(overall":[145],"concordance,":[146],"80.6%).":[147],"positive":[149],"likelihood":[150],"ratios":[151],"2.4,":[153],"13.6,":[154],"90.1":[156],"histologies,":[164,188],"respectively.":[165],"Concordant":[166],"between":[168],"resections":[171],"associated":[173,198],"a":[175,200,212],"higher":[176,201],"(median":[180],"tissue":[181,263],"blocks":[182,264],"concordant":[184],"vs":[186,190,205],"discordant":[187],"3":[189],"2;":[191],"P":[192,208],"<":[193,227],".002)":[194],"but":[195,229],"less":[197],"(median,":[203],"1.2":[204],"1.1":[206],"cm3;":[207],"=":[209,235],".06).":[210],"In":[211,238],"multivariate":[213],"analysis,":[214],"survival":[216],"independently":[218],"predicted":[219],"specimen":[225],"(P":[226,234],".0001)":[228],"biopsy":[233],".09).":[236],"Conclusions":[237],"contrast":[239],"histology,":[242],"highly":[248],"accurate.":[249],"Despite":[250],"increases":[258],"examined,":[265],"emphasizing":[266],"extensive":[271],"sampling":[272],"biopsies.":[275]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-08-13T00:00:00"}