{"id":"https://openalex.org/W2965788993","doi":"https://doi.org/10.1007/s11908-019-0686-5","title":"Contribution of Epithelial Cells to Defense Mechanisms in the Human Vagina","display_name":"Contribution of Epithelial Cells to Defense Mechanisms in the Human Vagina","publication_year":2019,"publication_date":"2019-08-01","ids":{"openalex":"https://openalex.org/W2965788993","doi":"https://doi.org/10.1007/s11908-019-0686-5","mag":"2965788993","pmid":"https://pubmed.ncbi.nlm.nih.gov/31367983"},"language":"en","primary_location":{"id":"doi:10.1007/s11908-019-0686-5","doi":"https://doi.org/10.1007/s11908-019-0686-5","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11908-019-0686-5","pdf_url":null,"source":{"id":"https://openalex.org/S110864905","display_name":"Current Infectious Disease Reports","issn_l":"1523-3847","issn":["1523-3847","1534-3146"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Infectious Disease Reports","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022292794","display_name":"Iara Moreno Linhares","orcid":"https://orcid.org/0000-0002-7846-6885","observed_orcids":["https://orcid.org/0000-0002-7846-6885"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Iara M. Linhares","raw_affiliation_strings":["Department of Gynecology and Obstetrics, University of Sao Paulo Medical School, Sao Paulo, Brazil. iara.linhares@yahoo.com.br","Department of Gynecology and Obstetrics, University of Sao Paulo Medical School, Sao Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology and Obstetrics, University of Sao Paulo Medical School, Sao Paulo, Brazil. iara.linhares@yahoo.com.br","institution_ids":["https://openalex.org/I17974374"]},{"raw_affiliation_string":"Department of Gynecology and Obstetrics, University of Sao Paulo Medical School, Sao Paulo, Brazil","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052652461","display_name":"Giovanni Sisti","orcid":"https://orcid.org/0000-0003-4152-0603","observed_orcids":["https://orcid.org/0000-0003-4152-0603"]},"institutions":[{"id":"https://openalex.org/I1281027232","display_name":"Lincoln Medical Center","ror":"https://ror.org/035a72598","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1281027232","https://openalex.org/I1283621791"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Giovanni Sisti","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Lincoln Medical and Mental Health Center, Bronx, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Lincoln Medical and Mental Health Center, Bronx, NY, USA","institution_ids":["https://openalex.org/I1281027232"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037795945","display_name":"Evelyn Eleni Minis","orcid":"https://orcid.org/0000-0003-1061-7699","observed_orcids":["https://orcid.org/0000-0003-1061-7699"]},"institutions":[{"id":"https://openalex.org/I1281027232","display_name":"Lincoln Medical Center","ror":"https://ror.org/035a72598","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1281027232","https://openalex.org/I1283621791"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Evelyn Minis","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Lincoln Medical and Mental Health Center, Bronx, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Lincoln Medical and Mental Health Center, Bronx, NY, USA","institution_ids":["https://openalex.org/I1281027232"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002123835","display_name":"Gabriela Bouf\u00e9lli de Freitas","orcid":"https://orcid.org/0000-0001-8585-4504","observed_orcids":["https://orcid.org/0000-0001-8585-4504"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Gabriela B. de Freitas","raw_affiliation_strings":["Department of Gynecology and Obstetrics, University of Sao Paulo Medical School, Sao Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology and Obstetrics, University of Sao Paulo Medical School, Sao Paulo, Brazil","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012520400","display_name":"Ant\u00f4nio Fernandes Moron","orcid":"https://orcid.org/0000-0002-7963-1758","observed_orcids":["https://orcid.org/0000-0002-7963-1758"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I88273585","display_name":"Universidade Federal de S\u00e3o Paulo","ror":"https://ror.org/02k5swt12","country_code":"BR","type":"education","lineage":["https://openalex.org/I88273585"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Antonio F. Moron","raw_affiliation_strings":["Department of Obstetrics, Federal University of Sao Paulo, Sao Paulo, Brazil","Institute of Tropical Medicine, University of Sao Paulo Medical School, Sao Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Federal University of Sao Paulo, Sao Paulo, Brazil","institution_ids":["https://openalex.org/I88273585"]},{"raw_affiliation_string":"Institute of Tropical Medicine, University of Sao Paulo Medical School, Sao Paulo, Brazil","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055608441","display_name":"Steven Sol Witkin","orcid":"https://orcid.org/0000-0002-3502-3929","observed_orcids":["https://orcid.org/0000-0002-3502-3929"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["BR","US"],"is_corresponding":false,"raw_author_name":"Steven S. Witkin","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York, NY, USA","Institute of Tropical Medicine, University of Sao Paulo Medical School, Sao Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Institute of Tropical Medicine, University of Sao Paulo Medical School, Sao Paulo, Brazil","institution_ids":["https://openalex.org/I17974374"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5022292794"],"corresponding_institution_ids":["https://openalex.org/I17974374"],"apc_list":{"value":3140,"currency":"USD","value_usd":3140},"apc_paid":null,"fwci":0.5856,"has_fulltext":false,"cited_by_count":36,"citation_normalized_percentile":{"value":0.4556962,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"21","issue":"9","first_page":"30","last_page":"30"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vaginal-epithelial-cells","display_name":"vaginal epithelial cells","score":0.9850000143051147},{"id":"https://openalex.org/keywords/vaginal-microbiota","display_name":"vaginal microbiota","score":0.8690000176429749},{"id":"https://openalex.org/keywords/vaginal-immunity","display_name":"vaginal immunity","score":0.5249999761581421},{"id":"https://openalex.org/keywords/lactobacillus-crispatus","display_name":"Lactobacillus crispatus","score":0.8679999709129333},{"id":"https://openalex.org/keywords/lactobacillus-iners","display_name":"Lactobacillus iners","score":0.9950000047683716},{"id":"https://openalex.org/keywords/gardnerella-vaginalis","display_name":"Gardnerella vaginalis","score":1.0},{"id":"https://openalex.org/keywords/autophagy","display_name":"autophagy","score":0.9570000171661377},{"id":"https://openalex.org/keywords/norepinephrine","display_name":"norepinephrine","score":0.8629999756813049},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.5849999785423279},{"id":"https://openalex.org/keywords/bacterial-translocation","display_name":"bacterial translocation","score":0.4390000104904175},{"id":"https://openalex.org/keywords/vaginal-acidity","display_name":"vaginal acidity","score":0.36399999260902405},{"id":"https://openalex.org/keywords/host-defense","display_name":"host defense","score":0.3630000054836273}],"concepts":[{"id":"https://openalex.org/C2777744392","wikidata":"https://www.wikidata.org/wiki/Q5880","display_name":"Vagina","level":2,"score":0.7816271781921387},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6727601289749146},{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.6638675332069397},{"id":"https://openalex.org/C2780018483","wikidata":"https://www.wikidata.org/wiki/Q127375","display_name":"Gardnerella vaginalis","level":3,"score":0.6589860916137695},{"id":"https://openalex.org/C2777165150","wikidata":"https://www.wikidata.org/wiki/Q269334","display_name":"Dysbiosis","level":3,"score":0.5396850109100342},{"id":"https://openalex.org/C2780236403","wikidata":"https://www.wikidata.org/wiki/Q2355641","display_name":"Lactobacillus crispatus","level":4,"score":0.5387495756149292},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4738500416278839},{"id":"https://openalex.org/C2780206646","wikidata":"https://www.wikidata.org/wiki/Q1061596","display_name":"Lactobacillus","level":3,"score":0.4451024532318115},{"id":"https://openalex.org/C529295009","wikidata":"https://www.wikidata.org/wiki/Q41301","display_name":"Epithelium","level":2,"score":0.43772000074386597},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.41864538192749023},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3863627314567566},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.3521885275840759},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.3408229947090149},{"id":"https://openalex.org/C2779952448","wikidata":"https://www.wikidata.org/wiki/Q804521","display_name":"Bacterial vaginosis","level":2,"score":0.21310067176818848},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.18580040335655212},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.13713234663009644},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.11501738429069519},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1007/s11908-019-0686-5","doi":"https://doi.org/10.1007/s11908-019-0686-5","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11908-019-0686-5","pdf_url":null,"source":{"id":"https://openalex.org/S110864905","display_name":"Current Infectious Disease Reports","issn_l":"1523-3847","issn":["1523-3847","1534-3146"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Infectious Disease Reports","raw_type":"journal-article"},{"id":"pmid:31367983","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31367983","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current infectious disease reports","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W1482715126","https://openalex.org/W1482747766","https://openalex.org/W1542745644","https://openalex.org/W1548772785","https://openalex.org/W1874817816","https://openalex.org/W1906460723","https://openalex.org/W1972270690","https://openalex.org/W1985403086","https://openalex.org/W1986029856","https://openalex.org/W1992645380","https://openalex.org/W2001213681","https://openalex.org/W2001624986","https://openalex.org/W2001644314","https://openalex.org/W2013371150","https://openalex.org/W2013553461","https://openalex.org/W2020988957","https://openalex.org/W2025661843","https://openalex.org/W2026269930","https://openalex.org/W2028325453","https://openalex.org/W2037895792","https://openalex.org/W2040601363","https://openalex.org/W2043958179","https://openalex.org/W2044206610","https://openalex.org/W2046487574","https://openalex.org/W2049257708","https://openalex.org/W2053000895","https://openalex.org/W2069072974","https://openalex.org/W2071962829","https://openalex.org/W2087429133","https://openalex.org/W2111415362","https://openalex.org/W2125503055","https://openalex.org/W2137417707","https://openalex.org/W2142241097","https://openalex.org/W2147161211","https://openalex.org/W2150869338","https://openalex.org/W2161967568","https://openalex.org/W2165424875","https://openalex.org/W2281005810","https://openalex.org/W2462018274","https://openalex.org/W2549584821","https://openalex.org/W2572899228","https://openalex.org/W2587409612","https://openalex.org/W2597003948","https://openalex.org/W2615259178","https://openalex.org/W2749873900","https://openalex.org/W2753721796","https://openalex.org/W2760675072","https://openalex.org/W2782726647","https://openalex.org/W2892490860","https://openalex.org/W2897605203","https://openalex.org/W2924774534"],"related_works":["https://openalex.org/W2911503359","https://openalex.org/W2597003948","https://openalex.org/W2807270740","https://openalex.org/W2753721796","https://openalex.org/W3199219251","https://openalex.org/W2127934824","https://openalex.org/W2170665356","https://openalex.org/W1545166364","https://openalex.org/W1986029856","https://openalex.org/W2470391433"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-08-13T00:00:00"}