{"id":"https://openalex.org/W2965685443","doi":"https://doi.org/10.1016/j.ejmp.2019.07.021","title":"Breast deformation during the course of radiotherapy: The need for an additional outer margin","display_name":"Breast deformation during the course of radiotherapy: The need for an additional outer margin","publication_year":2019,"publication_date":"2019-08-05","ids":{"openalex":"https://openalex.org/W2965685443","doi":"https://doi.org/10.1016/j.ejmp.2019.07.021","mag":"2965685443","pmid":"https://pubmed.ncbi.nlm.nih.gov/31430580"},"language":"en","primary_location":{"id":"doi:10.1016/j.ejmp.2019.07.021","doi":"https://doi.org/10.1016/j.ejmp.2019.07.021","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ejmp.2019.07.021","pdf_url":null,"source":{"id":"https://openalex.org/S138998826","display_name":"Physica Medica","issn_l":"1120-1797","issn":["1120-1797","1724-191X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physica Medica","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082635201","display_name":"Jan Sepp\u00e4l\u00e4","orcid":"https://orcid.org/0000-0002-0922-329X","observed_orcids":["https://orcid.org/0000-0002-0922-329X"]},"institutions":[{"id":"https://openalex.org/I4210092991","display_name":"Kuopio University Hospital","ror":"https://ror.org/00fqdfs68","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I4210092991","https://openalex.org/I4405278559"]}],"countries":["FI"],"is_corresponding":true,"raw_author_name":"J. Sepp\u00e4l\u00e4","raw_affiliation_strings":["Center of Oncology, Kuopio University Hospital, Kuopio, Finland. Electronic address: jan.seppala@kuh.fi","Center of Oncology, Kuopio University Hospital, Kuopio, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Oncology, Kuopio University Hospital, Kuopio, Finland. Electronic address: jan.seppala@kuh.fi","institution_ids":["https://openalex.org/I4210092991"]},{"raw_affiliation_string":"Center of Oncology, Kuopio University Hospital, Kuopio, Finland","institution_ids":["https://openalex.org/I4210092991"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027096421","display_name":"Kristiina Vuolukka","orcid":"https://orcid.org/0000-0001-9067-0566","observed_orcids":["https://orcid.org/0000-0001-9067-0566"]},"institutions":[{"id":"https://openalex.org/I4210092991","display_name":"Kuopio University Hospital","ror":"https://ror.org/00fqdfs68","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I4210092991","https://openalex.org/I4405278559"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"K. Vuolukka","raw_affiliation_strings":["Center of Oncology, Kuopio University Hospital, Kuopio, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Oncology, Kuopio University Hospital, Kuopio, Finland","institution_ids":["https://openalex.org/I4210092991"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085239761","display_name":"Tuomas Vir\u00e9n","orcid":"https://orcid.org/0000-0002-7685-7911","observed_orcids":["https://orcid.org/0000-0002-7685-7911"]},"institutions":[{"id":"https://openalex.org/I4210092991","display_name":"Kuopio University Hospital","ror":"https://ror.org/00fqdfs68","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I4210092991","https://openalex.org/I4405278559"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"T. Vir\u00e9n","raw_affiliation_strings":["Center of Oncology, Kuopio University Hospital, Kuopio, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Oncology, Kuopio University Hospital, Kuopio, Finland","institution_ids":["https://openalex.org/I4210092991"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037404963","display_name":"Janne Heikkil\u00e4","orcid":"https://orcid.org/0000-0003-1767-5779","observed_orcids":["https://orcid.org/0000-0003-1767-5779"]},"institutions":[{"id":"https://openalex.org/I4210092991","display_name":"Kuopio University Hospital","ror":"https://ror.org/00fqdfs68","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I4210092991","https://openalex.org/I4405278559"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"J. Heikkil\u00e4","raw_affiliation_strings":["Center of Oncology, Kuopio University Hospital, Kuopio, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Oncology, Kuopio University Hospital, Kuopio, Finland","institution_ids":["https://openalex.org/I4210092991"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073825329","display_name":"Juuso T. J. Honkanen","orcid":"https://orcid.org/0000-0002-9150-9253","observed_orcids":["https://orcid.org/0000-0002-9150-9253"]},"institutions":[{"id":"https://openalex.org/I4210092991","display_name":"Kuopio University Hospital","ror":"https://ror.org/00fqdfs68","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I4210092991","https://openalex.org/I4405278559"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"J.T.J. Honkanen","raw_affiliation_strings":["Center of Oncology, Kuopio University Hospital, Kuopio, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Oncology, Kuopio University Hospital, Kuopio, Finland","institution_ids":["https://openalex.org/I4210092991"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102971703","display_name":"Awadhesh Kumar Pandey","orcid":"https://orcid.org/0000-0003-1197-564X","observed_orcids":["https://orcid.org/0000-0003-1197-564X"]},"institutions":[{"id":"https://openalex.org/I175532246","display_name":"University of Eastern Finland","ror":"https://ror.org/00cyydd11","country_code":"FI","type":"education","lineage":["https://openalex.org/I175532246"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"A. Pandey","raw_affiliation_strings":["Department of Applied Physics, University of Eastern Finland, Kuopio, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Applied Physics, University of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027108708","display_name":"A. Al-Gburi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I175532246","display_name":"University of Eastern Finland","ror":"https://ror.org/00cyydd11","country_code":"FI","type":"education","lineage":["https://openalex.org/I175532246"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"A. Al-Gburi","raw_affiliation_strings":["Department of Applied Physics, University of Eastern Finland, Kuopio, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Applied Physics, University of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]}]},{"author_position":"middle","author":{"id":null,"display_name":"M. Shah","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I175532246","display_name":"University of Eastern Finland","ror":"https://ror.org/00cyydd11","country_code":"FI","type":"education","lineage":["https://openalex.org/I175532246"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"M. Shah","raw_affiliation_strings":["Department of Applied Physics, University of Eastern Finland, Kuopio, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Applied Physics, University of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029633383","display_name":"S. Sefa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I175532246","display_name":"University of Eastern Finland","ror":"https://ror.org/00cyydd11","country_code":"FI","type":"education","lineage":["https://openalex.org/I175532246"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"S. Sefa","raw_affiliation_strings":["Department of Applied Physics, University of Eastern Finland, Kuopio, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Applied Physics, University of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]}]},{"author_position":"last","author":{"id":null,"display_name":"T. Koivum\u00e4ki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210140036","display_name":"Central Finland Health Care District","ror":"https://ror.org/054h11b04","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I4210140036"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"T. Koivum\u00e4ki","raw_affiliation_strings":["Department of Medical Physics, Central Finland Central Hospital, Jyv\u00e4skyl\u00e4, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Physics, Central Finland Central Hospital, Jyv\u00e4skyl\u00e4, Finland","institution_ids":["https://openalex.org/I4210140036"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5082635201"],"corresponding_institution_ids":["https://openalex.org/I4210092991"],"apc_list":{"value":1800,"currency":"USD","value_usd":1800},"apc_paid":null,"fwci":3.3761,"has_fulltext":false,"cited_by_count":36,"citation_normalized_percentile":{"value":0.93184634,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"65","issue":null,"first_page":"1","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-deformation","display_name":"breast deformation","score":0.9779999852180481},{"id":"https://openalex.org/keywords/breast-cancer-radiotherapy","display_name":"breast cancer radiotherapy","score":0.9779999852180481},{"id":"https://openalex.org/keywords/breast-conserving-surgery","display_name":"breast-conserving surgery","score":0.7319999933242798},{"id":"https://openalex.org/keywords/3d-registration","display_name":"3D registration","score":0.8460000157356262},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.8349999785423279},{"id":"https://openalex.org/keywords/chest-wall","display_name":"chest wall","score":0.44600000977516174},{"id":"https://openalex.org/keywords/axillary-lymph-nodes","display_name":"axillary lymph nodes","score":0.7870000004768372},{"id":"https://openalex.org/keywords/inverse-planning","display_name":"inverse treatment planning","score":0.6079999804496765},{"id":"https://openalex.org/keywords/dose-coverage","display_name":"dose coverage","score":0.30399999022483826}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7456610798835754},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.7325088381767273},{"id":"https://openalex.org/C2781467025","wikidata":"https://www.wikidata.org/wiki/Q4959754","display_name":"Breast-conserving surgery","level":5,"score":0.7149927616119385},{"id":"https://openalex.org/C774472","wikidata":"https://www.wikidata.org/wiki/Q6760393","display_name":"Margin (machine learning)","level":2,"score":0.591218113899231},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.5629708766937256},{"id":"https://openalex.org/C179671157","wikidata":"https://www.wikidata.org/wiki/Q2422612","display_name":"Sentinel node","level":4,"score":0.4909246265888214},{"id":"https://openalex.org/C2780849966","wikidata":"https://www.wikidata.org/wiki/Q170758","display_name":"Lymph node","level":2,"score":0.4526894986629486},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.4268917441368103},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.417753666639328},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.3806843161582947},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.25159668922424316},{"id":"https://openalex.org/C2777757722","wikidata":"https://www.wikidata.org/wiki/Q848318","display_name":"Mastectomy","level":4,"score":0.19471225142478943},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1297895312309265},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.058966249227523804},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001940","descriptor_name":"Breast","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001940","descriptor_name":"Breast","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001940","descriptor_name":"Breast","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011879","descriptor_name":"Radiotherapy Dosage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011880","descriptor_name":"Radiotherapy Planning, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050397","descriptor_name":"Radiotherapy, Intensity-Modulated","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054893","descriptor_name":"Cone-Beam Computed Tomography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.ejmp.2019.07.021","doi":"https://doi.org/10.1016/j.ejmp.2019.07.021","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ejmp.2019.07.021","pdf_url":null,"source":{"id":"https://openalex.org/S138998826","display_name":"Physica Medica","issn_l":"1120-1797","issn":["1120-1797","1724-191X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physica Medica","raw_type":"journal-article"},{"id":"pmid:31430580","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31430580","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W1962860756","https://openalex.org/W1964812369","https://openalex.org/W1975556891","https://openalex.org/W1996932415","https://openalex.org/W2009743716","https://openalex.org/W2012048178","https://openalex.org/W2012554619","https://openalex.org/W2030273299","https://openalex.org/W2033251856","https://openalex.org/W2047927113","https://openalex.org/W2054048807","https://openalex.org/W2072013234","https://openalex.org/W2072759723","https://openalex.org/W2075111937","https://openalex.org/W2075931376","https://openalex.org/W2096499183","https://openalex.org/W2100025800","https://openalex.org/W2108409127","https://openalex.org/W2109091750","https://openalex.org/W2140849863","https://openalex.org/W2150553852","https://openalex.org/W2208983503","https://openalex.org/W2519342356","https://openalex.org/W2614127902","https://openalex.org/W2753102348","https://openalex.org/W2776232258","https://openalex.org/W2779433803","https://openalex.org/W2809654699","https://openalex.org/W2848242093","https://openalex.org/W2883844881"],"related_works":["https://openalex.org/W3211299117","https://openalex.org/W4415062375","https://openalex.org/W4322758151","https://openalex.org/W7166657166","https://openalex.org/W4414534157","https://openalex.org/W1964797791","https://openalex.org/W7165392809","https://openalex.org/W4205703663","https://openalex.org/W4411398232","https://openalex.org/W2807622537"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-08-13T00:00:00"}