{"id":"https://openalex.org/W2964560984","doi":"https://doi.org/10.2196/14675","title":"Cost-Effectiveness of Therapist-Guided Internet-Based Cognitive Behavioral Therapy for Stress-Related Disorders: Secondary Analysis of a Randomized Controlled Trial","display_name":"Cost-Effectiveness of Therapist-Guided Internet-Based Cognitive Behavioral Therapy for Stress-Related Disorders: Secondary Analysis of a Randomized Controlled Trial","publication_year":2019,"publication_date":"2019-07-27","ids":{"openalex":"https://openalex.org/W2964560984","doi":"https://doi.org/10.2196/14675","mag":"2964560984","pmid":"https://pubmed.ncbi.nlm.nih.gov/31586370","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6788336"},"language":"en","primary_location":{"id":"doi:10.2196/14675","doi":"https://doi.org/10.2196/14675","is_oa":true,"landing_page_url":"https://doi.org/10.2196/14675","pdf_url":"https://www.jmir.org/2019/9/e14675/PDF","source":{"id":"https://openalex.org/S17147534","display_name":"Journal of Medical Internet Research","issn_l":"1438-8871","issn":["1438-8871","1439-4456"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","fnege-4","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320608","host_organization_name":"JMIR Publications","host_organization_lineage":["https://openalex.org/P4310320608"],"host_organization_lineage_names":["JMIR Publications"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Internet Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.jmir.org/2019/9/e14675/PDF","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037114255","display_name":"Elin Linds\u00e4ter","orcid":"https://orcid.org/0000-0003-2547-9196","observed_orcids":["https://orcid.org/0000-0003-2547-9196","https://orcid.org/0000-0001-6308-8407"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Elin Linds\u00e4ter","raw_affiliation_strings":["Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":"https://orcid.org/0000-0003-2547-9196","affiliations":[{"raw_affiliation_string":"Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047646541","display_name":"Erland Axelsson","orcid":"https://orcid.org/0000-0003-2562-2925","observed_orcids":["https://orcid.org/0000-0003-2562-2925"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Erland Axelsson","raw_affiliation_strings":["Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":"https://orcid.org/0000-0003-2562-2925","affiliations":[{"raw_affiliation_string":"Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064015640","display_name":"Sigrid Salomonsson","orcid":"https://orcid.org/0000-0002-6713-5933","observed_orcids":["https://orcid.org/0000-0002-6713-5933"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Sigrid Salomonsson","raw_affiliation_strings":["Center for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden","Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":"https://orcid.org/0000-0002-6713-5933","affiliations":[{"raw_affiliation_string":"Center for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048866503","display_name":"Fredrik Santoft","orcid":"https://orcid.org/0000-0003-0673-6521","observed_orcids":["https://orcid.org/0000-0003-0673-6521"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Fredrik Santoft","raw_affiliation_strings":["Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":"https://orcid.org/0000-0003-0673-6521","affiliations":[{"raw_affiliation_string":"Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079099541","display_name":"Brj\u00e1nn Lj\u00f3tsson","orcid":"https://orcid.org/0000-0001-8086-1668","observed_orcids":["https://orcid.org/0000-0001-8086-1668"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Brj\u00e1nn Lj\u00f3tsson","raw_affiliation_strings":["Center for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden","Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":"https://orcid.org/0000-0001-8086-1668","affiliations":[{"raw_affiliation_string":"Center for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091600688","display_name":"Torbj\u00f6rn \u00c5kerstedt","orcid":"https://orcid.org/0000-0001-8049-8504","observed_orcids":["https://orcid.org/0000-0001-8049-8504"]},"institutions":[{"id":"https://openalex.org/I161593684","display_name":"Stockholm University","ror":"https://ror.org/05f0yaq80","country_code":"SE","type":"education","lineage":["https://openalex.org/I161593684"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Torbj\u00f6rn \u00c5kerstedt","raw_affiliation_strings":["Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden","Stress Research Institute, Stockholm University, Stockholm, Sweden"],"raw_orcid":"https://orcid.org/0000-0001-8049-8504","affiliations":[{"raw_affiliation_string":"Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Stress Research Institute, Stockholm University, Stockholm, Sweden","institution_ids":["https://openalex.org/I161593684"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073745780","display_name":"Mats Lekander","orcid":"https://orcid.org/0000-0003-3998-1494","observed_orcids":["https://orcid.org/0000-0003-3998-1494"]},"institutions":[{"id":"https://openalex.org/I161593684","display_name":"Stockholm University","ror":"https://ror.org/05f0yaq80","country_code":"SE","type":"education","lineage":["https://openalex.org/I161593684"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Mats Lekander","raw_affiliation_strings":["Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden","Osher Center for Integrative Medicine, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden","Stress Research Institute, Stockholm University, Stockholm, Sweden"],"raw_orcid":"https://orcid.org/0000-0003-3998-1494","affiliations":[{"raw_affiliation_string":"Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Osher Center for Integrative Medicine, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Stress Research Institute, Stockholm University, Stockholm, Sweden","institution_ids":["https://openalex.org/I161593684"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042507418","display_name":"Erik Hedman\u2010Lagerl\u00f6f","orcid":"https://orcid.org/0000-0002-7939-9848","observed_orcids":["https://orcid.org/0000-0002-7939-9848"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Erik Hedman-Lagerl\u00f6f","raw_affiliation_strings":["Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden","Osher Center for Integrative Medicine, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":"https://orcid.org/0000-0002-7939-9848","affiliations":[{"raw_affiliation_string":"Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Osher Center for Integrative Medicine, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5037114255"],"corresponding_institution_ids":["https://openalex.org/I28166907"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":4.5159,"has_fulltext":true,"cited_by_count":27,"citation_normalized_percentile":{"value":0.94285714,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"21","issue":"9","first_page":"e14675","last_page":"e14675"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11519","display_name":"Digital Mental Health Interventions","score":0.9272000193595886,"subfield":{"id":"https://openalex.org/subfields/3202","display_name":"Applied Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T11519","display_name":"Digital Mental Health Interventions","score":0.9272000193595886,"subfield":{"id":"https://openalex.org/subfields/3202","display_name":"Applied Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10804","display_name":"Health Systems, Economic Evaluations, Quality of Life","score":0.0674000009894371,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10912","display_name":"Telemedicine and Telehealth Implementation","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/internet-based-cognitive-behavioral-therapy","display_name":"internet-based cognitive behavioral therapy","score":0.9139999747276306},{"id":"https://openalex.org/keywords/stress-related-disorders","display_name":"stress-related disorders","score":0.8479999899864197},{"id":"https://openalex.org/keywords/adjustment-disorder","display_name":"adjustment disorder","score":0.996999979019165},{"id":"https://openalex.org/keywords/exhaustion-disorder","display_name":"exhaustion disorder","score":0.9649999737739563},{"id":"https://openalex.org/keywords/cost-effectiveness","display_name":"cost-effectiveness","score":0.968999981880188},{"id":"https://openalex.org/keywords/cost-utility-analysis","display_name":"cost-utility analysis","score":0.9240000247955322},{"id":"https://openalex.org/keywords/remission-rate","display_name":"remission rate","score":0.7319999933242798},{"id":"https://openalex.org/keywords/health-related-quality-of-life","display_name":"health-related quality of life","score":0.9950000047683716},{"id":"https://openalex.org/keywords/wait-list-control","display_name":"waitlist control","score":0.6589999794960022}],"concepts":[{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.7069728374481201},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.6345888376235962},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5466263294219971},{"id":"https://openalex.org/C2776125615","wikidata":"https://www.wikidata.org/wiki/Q18391886","display_name":"Economic evaluation","level":2,"score":0.5106661915779114},{"id":"https://openalex.org/C2781265626","wikidata":"https://www.wikidata.org/wiki/Q1147152","display_name":"Cognitive behavioral therapy","level":3,"score":0.5087264180183411},{"id":"https://openalex.org/C3019080777","wikidata":"https://www.wikidata.org/wiki/Q1754768","display_name":"Cost effectiveness","level":2,"score":0.48211121559143066},{"id":"https://openalex.org/C2777364431","wikidata":"https://www.wikidata.org/wiki/Q140813","display_name":"Willingness to pay","level":2,"score":0.4696212112903595},{"id":"https://openalex.org/C64332521","wikidata":"https://www.wikidata.org/wiki/Q614165","display_name":"Quality-adjusted life year","level":3,"score":0.44905638694763184},{"id":"https://openalex.org/C2779477915","wikidata":"https://www.wikidata.org/wiki/Q13693745","display_name":"Cognitive therapy","level":3,"score":0.4440971612930298},{"id":"https://openalex.org/C127454912","wikidata":"https://www.wikidata.org/wiki/Q942582","display_name":"Cost\u2013benefit analysis","level":2,"score":0.4269052743911743},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.38311827182769775},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.3257310390472412},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1165628433227539},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.09354585409164429},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.06889525055885315},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0},{"id":"https://openalex.org/C175444787","wikidata":"https://www.wikidata.org/wiki/Q39072","display_name":"Microeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003362","descriptor_name":"Cost-Benefit Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D015928","descriptor_name":"Cognitive Behavioral Therapy","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D015928","descriptor_name":"Cognitive Behavioral Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040701","descriptor_name":"Stress Disorders, Traumatic, Acute","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D040701","descriptor_name":"Stress Disorders, Traumatic, Acute","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.2196/14675","doi":"https://doi.org/10.2196/14675","is_oa":true,"landing_page_url":"https://doi.org/10.2196/14675","pdf_url":"https://www.jmir.org/2019/9/e14675/PDF","source":{"id":"https://openalex.org/S17147534","display_name":"Journal of Medical Internet Research","issn_l":"1438-8871","issn":["1438-8871","1439-4456"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","fnege-4","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320608","host_organization_name":"JMIR Publications","host_organization_lineage":["https://openalex.org/P4310320608"],"host_organization_lineage_names":["JMIR Publications"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Internet Research","raw_type":"journal-article"},{"id":"doi:10.2196/preprints.14675","doi":"https://doi.org/10.2196/preprints.14675","is_oa":true,"landing_page_url":"https://doi.org/10.2196/preprints.14675","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},{"id":"pmh:oai:europepmc.org:5789674","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6788336","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6788336","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6788336","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Med Internet Res","raw_type":"Text"},{"id":"pmid:31586370","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31586370","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of medical Internet research","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.2196/14675","doi":"https://doi.org/10.2196/14675","is_oa":true,"landing_page_url":"https://doi.org/10.2196/14675","pdf_url":"https://www.jmir.org/2019/9/e14675/PDF","source":{"id":"https://openalex.org/S17147534","display_name":"Journal of Medical Internet Research","issn_l":"1438-8871","issn":["1438-8871","1439-4456"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","fnege-4","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320608","host_organization_name":"JMIR Publications","host_organization_lineage":["https://openalex.org/P4310320608"],"host_organization_lineage_names":["JMIR Publications"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Internet Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9907000064849854,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322315","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691"},{"id":"https://openalex.org/F4320322570","display_name":"Stockholms L\u00e4ns Landsting","ror":"https://ror.org/02zrae794"},{"id":"https://openalex.org/F4320327874","display_name":"Stockholm Stress Center","ror":"https://ror.org/009jqbg55"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2964560984.pdf","grobid_xml":"https://content.openalex.org/works/W2964560984.grobid-xml"},"referenced_works_count":59,"referenced_works":["https://openalex.org/W1516183819","https://openalex.org/W1572252684","https://openalex.org/W1586312579","https://openalex.org/W1595046345","https://openalex.org/W1761187091","https://openalex.org/W1945015642","https://openalex.org/W1976695006","https://openalex.org/W1983555748","https://openalex.org/W1988321620","https://openalex.org/W1993122355","https://openalex.org/W1996299251","https://openalex.org/W2009348399","https://openalex.org/W2017517475","https://openalex.org/W2022448393","https://openalex.org/W2028532700","https://openalex.org/W2029468434","https://openalex.org/W2031608759","https://openalex.org/W2033540418","https://openalex.org/W2036392798","https://openalex.org/W2036735145","https://openalex.org/W2047797070","https://openalex.org/W2055109448","https://openalex.org/W2064006234","https://openalex.org/W2064869088","https://openalex.org/W2071233982","https://openalex.org/W2110371849","https://openalex.org/W2112336497","https://openalex.org/W2116499890","https://openalex.org/W2119475196","https://openalex.org/W2130267399","https://openalex.org/W2138758538","https://openalex.org/W2141051648","https://openalex.org/W2142956558","https://openalex.org/W2143280830","https://openalex.org/W2144101679","https://openalex.org/W2153836018","https://openalex.org/W2154971771","https://openalex.org/W2157363310","https://openalex.org/W2167388475","https://openalex.org/W2170816348","https://openalex.org/W2170967664","https://openalex.org/W2245231029","https://openalex.org/W2255927482","https://openalex.org/W2473786944","https://openalex.org/W2542567848","https://openalex.org/W2549663075","https://openalex.org/W2554099036","https://openalex.org/W2569066059","https://openalex.org/W2581338065","https://openalex.org/W2589092816","https://openalex.org/W2599271079","https://openalex.org/W2740553877","https://openalex.org/W2766891788","https://openalex.org/W2770802215","https://openalex.org/W2808129767","https://openalex.org/W2884273194","https://openalex.org/W2885146643","https://openalex.org/W2907689835","https://openalex.org/W3171418018"],"related_works":["https://openalex.org/W2116499890","https://openalex.org/W2884273194","https://openalex.org/W4405820469","https://openalex.org/W2999458041","https://openalex.org/W2066192332","https://openalex.org/W2039973016","https://openalex.org/W2123126598","https://openalex.org/W2119927336","https://openalex.org/W2753086693","https://openalex.org/W2343313084"],"abstract_inverted_index":{"BACKGROUND:":[0],"Stress-related":[1],"disorders":[2,25,56],"are":[3],"associated":[4,186],"with":[5,54,73,98,181,187,271],"significant":[6],"suffering,":[7],"functional":[8],"impairment,":[9],"and":[10,48,124,129,141,184,214],"high":[11],"societal":[12,243,285],"costs.":[13,287],"Internet-based":[14],"cognitive":[15],"behavioral":[16],"therapy":[17],"(ICBT)":[18],"is":[19,259],"a":[20,74,99,104,118,199,206,215,222,260],"promising":[21],"treatment":[22,262],"for":[23,52,263,275],"stress-related":[24,55],"but":[26],"has":[27],"so":[28],"far":[29],"not":[30],"been":[31],"subjected":[32],"to":[33,44,113,156,176,195,208,234],"health":[34],"economic":[35,92],"evaluation.":[36],"OBJECTIVE:":[37],"The":[38,164,227,254],"objective":[39],"of":[40,50,60,103,150,160,202,211,218,224,238,250],"this":[41],"study":[42],"was":[43,154,172,185],"evaluate":[45],"the":[46,58,158,168,182,248],"cost-effectiveness":[47,134],"cost-utility":[49,143],"ICBT":[51,106,115,174,197,231,258,274],"patients":[53,109,264,277],"in":[57,96,107,191,236],"form":[59],"adjustment":[61],"disorder":[62,66],"(AD)":[63],"or":[64,117,268,283],"exhaustion":[65],"(ED).":[67],"We":[68,131],"hypothesized":[69],"that":[70,167,173,230,257],"ICBT,":[71],"compared":[72,180],"waitlist":[75],"control":[76],"(WLC)":[77],"group,":[78],"would":[79],"generate":[80],"improvements":[81,235],"at":[82,205,221,240,281],"low":[83],"net":[84,242,286],"costs,":[85],"thereby":[86],"making":[87],"it":[88],"cost-effective.":[89],"METHODS:":[90],"Health":[91,122],"data":[93],"were":[94,111,126],"obtained":[95],"tandem":[97],"randomized":[100,112],"controlled":[101],"trial":[102],"12-week":[105],"which":[108],"(N=100)":[110],"an":[114],"(n=50)":[116,120],"WLC":[119,183],"group.":[121],"outcomes":[123],"costs":[125,192],"surveyed":[127],"pre-":[128,194],"posttreatment.":[130,196],"calculated":[132],"incremental":[133,142],"ratios":[135,144],"(ICERs)":[136],"based":[137,146],"on":[138,147],"remission":[139,178],"rates":[140,179],"(ICURs)":[145],"health-related":[148],"quality":[149,237],"life.":[151],"Bootstrap":[152],"sampling":[153],"used":[155],"assess":[157],"uncertainty":[159],"our":[161,251],"results.":[162,252],"RESULTS:":[163],"ICER":[165],"indicated":[166,229],"most":[169],"likely":[170],"scenario":[171],"led":[175,233],"higher":[177],"slightly":[188],"larger":[189],"reductions":[190],"from":[193,266],"had":[198],"60%":[200],"probability":[201,217],"being":[203,219],"cost-effective":[204,220,261],"willingness":[207],"pay":[209],"(WTP)":[210],"US":[212,225],"$0":[213],"96%":[216],"WTP":[223],"$1000.":[226],"ICUR":[228],"also":[232],"life":[239],"no":[241,272,282],"cost.":[244],"Sensitivity":[245],"analyses":[246],"supported":[247],"robustness":[249],"CONCLUSIONS:":[253],"results":[255],"suggest":[256],"suffering":[265],"AD":[267],"ED.":[269],"Compared":[270],"treatment,":[273],"these":[276],"yields":[278],"large":[279],"effects":[280],"minimal":[284],"TRIAL":[288],"REGISTRATION:":[289],"ClinicalTrials.gov":[290],"NCT02540317;":[291],"https://clinicaltrials.gov/ct2/show/NCT02540317.":[292]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":4},{"year":2018,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-08-13T00:00:00"}