{"id":"https://openalex.org/W2964249043","doi":"https://doi.org/10.1038/s41598-019-46901-6","title":"Targeted detection of Dehalococcoides mccartyi microbial protein biomarkers as indicators of reductive dechlorination activity in contaminated groundwater","display_name":"Targeted detection of Dehalococcoides mccartyi microbial protein biomarkers as indicators of reductive dechlorination activity in contaminated groundwater","publication_year":2019,"publication_date":"2019-07-22","ids":{"openalex":"https://openalex.org/W2964249043","doi":"https://doi.org/10.1038/s41598-019-46901-6","mag":"2964249043","pmid":"https://pubmed.ncbi.nlm.nih.gov/31332202","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6646388"},"language":"en","primary_location":{"id":"doi:10.1038/s41598-019-46901-6","doi":"https://doi.org/10.1038/s41598-019-46901-6","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-019-46901-6","pdf_url":"https://www.nature.com/articles/s41598-019-46901-6.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41598-019-46901-6.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000646154","display_name":"Manuel I. Villalobos Solis","orcid":"https://orcid.org/0000-0002-9053-932X","observed_orcids":["https://orcid.org/0000-0002-9053-932X"]},"institutions":[{"id":"https://openalex.org/I1289243028","display_name":"Oak Ridge National Laboratory","ror":"https://ror.org/01qz5mb56","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289243028","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I4210159294"]},{"id":"https://openalex.org/I75027704","display_name":"University of Tennessee at Knoxville","ror":"https://ror.org/020f3ap87","country_code":"US","type":"education","lineage":["https://openalex.org/I75027704"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Manuel I. Villalobos Solis","raw_affiliation_strings":["Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, 37831, United States","Department of Genome Science and Technology, University of Tennessee, Knoxville, Tennessee, 37996, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, 37831, United States","institution_ids":["https://openalex.org/I1289243028"]},{"raw_affiliation_string":"Department of Genome Science and Technology, University of Tennessee, Knoxville, Tennessee, 37996, United States","institution_ids":["https://openalex.org/I75027704"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087741198","display_name":"Paul E. Abraham","orcid":"https://orcid.org/0000-0003-2685-9123","observed_orcids":["https://orcid.org/0000-0003-2685-9123"]},"institutions":[{"id":"https://openalex.org/I1289243028","display_name":"Oak Ridge National Laboratory","ror":"https://ror.org/01qz5mb56","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289243028","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I4210159294"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul E. Abraham","raw_affiliation_strings":["Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, 37831, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, 37831, United States","institution_ids":["https://openalex.org/I1289243028"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070899864","display_name":"Karuna Chourey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1289243028","display_name":"Oak Ridge National Laboratory","ror":"https://ror.org/01qz5mb56","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289243028","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I4210159294"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karuna Chourey","raw_affiliation_strings":["Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, 37831, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, 37831, United States","institution_ids":["https://openalex.org/I1289243028"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020409383","display_name":"Cynthia M. Swift","orcid":"https://orcid.org/0000-0002-8878-2419","observed_orcids":["https://orcid.org/0000-0002-8878-2419"]},"institutions":[{"id":"https://openalex.org/I75027704","display_name":"University of Tennessee at Knoxville","ror":"https://ror.org/020f3ap87","country_code":"US","type":"education","lineage":["https://openalex.org/I75027704"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cynthia M. Swift","raw_affiliation_strings":["Department of Microbiology, Department of Civil and Environmental Engineering, Department of Biosystems Engineering and Soil Science, University of Tennessee, Knoxville, Tennessee, 37996, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Department of Civil and Environmental Engineering, Department of Biosystems Engineering and Soil Science, University of Tennessee, Knoxville, Tennessee, 37996, United States","institution_ids":["https://openalex.org/I75027704"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110649430","display_name":"Frank E. L\u00f6ffler","orcid":"https://orcid.org/0000-0002-9797-4279","observed_orcids":["https://orcid.org/0000-0002-9797-4279"]},"institutions":[{"id":"https://openalex.org/I1289243028","display_name":"Oak Ridge National Laboratory","ror":"https://ror.org/01qz5mb56","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289243028","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I4210159294"]},{"id":"https://openalex.org/I75027704","display_name":"University of Tennessee at Knoxville","ror":"https://ror.org/020f3ap87","country_code":"US","type":"education","lineage":["https://openalex.org/I75027704"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Frank E. L\u00f6ffler","raw_affiliation_strings":["Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, 37831, United States. frank.loeffler@utk.edu","Department of Microbiology, Department of Civil and Environmental Engineering, Department of Biosystems Engineering and Soil Science, University of Tennessee, Knoxville, Tennessee, 37996, United States. frank.loeffler@utk.edu","Department of Microbiology, Department of Civil and Environmental Engineering, Department of Biosystems Engineering and Soil Science, University of Tennessee, Knoxville, Tennessee, 37996, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, 37831, United States. frank.loeffler@utk.edu","institution_ids":["https://openalex.org/I1289243028"]},{"raw_affiliation_string":"Department of Microbiology, Department of Civil and Environmental Engineering, Department of Biosystems Engineering and Soil Science, University of Tennessee, Knoxville, Tennessee, 37996, United States. frank.loeffler@utk.edu","institution_ids":["https://openalex.org/I75027704"]},{"raw_affiliation_string":"Department of Microbiology, Department of Civil and Environmental Engineering, Department of Biosystems Engineering and Soil Science, University of Tennessee, Knoxville, Tennessee, 37996, United States","institution_ids":["https://openalex.org/I75027704"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002596998","display_name":"Robert L. Hettich","orcid":"https://orcid.org/0000-0001-7708-786X","observed_orcids":["https://orcid.org/0000-0001-7708-786X"]},"institutions":[{"id":"https://openalex.org/I1289243028","display_name":"Oak Ridge National Laboratory","ror":"https://ror.org/01qz5mb56","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289243028","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I4210159294"]},{"id":"https://openalex.org/I75027704","display_name":"University of Tennessee at Knoxville","ror":"https://ror.org/020f3ap87","country_code":"US","type":"education","lineage":["https://openalex.org/I75027704"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Robert L. Hettich","raw_affiliation_strings":["Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, 37831, United States. hettichrl@ornl.gov","Department of Genome Science and Technology, University of Tennessee, Knoxville, Tennessee, 37996, United States. hettichrl@ornl.gov","Department of Genome Science and Technology, University of Tennessee, Knoxville, Tennessee, 37996, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, 37831, United States. hettichrl@ornl.gov","institution_ids":["https://openalex.org/I1289243028"]},{"raw_affiliation_string":"Department of Genome Science and Technology, University of Tennessee, Knoxville, Tennessee, 37996, United States. hettichrl@ornl.gov","institution_ids":["https://openalex.org/I75027704"]},{"raw_affiliation_string":"Department of Genome Science and Technology, University of Tennessee, Knoxville, Tennessee, 37996, United States","institution_ids":["https://openalex.org/I75027704"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5002596998","https://openalex.org/A5110649430"],"corresponding_institution_ids":["https://openalex.org/I1289243028","https://openalex.org/I75027704"],"apc_list":{"value":1790,"currency":"USD","value_usd":1790},"apc_paid":{"value":1790,"currency":"USD","value_usd":1790},"fwci":0.599,"has_fulltext":true,"cited_by_count":16,"citation_normalized_percentile":{"value":0.63333173,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"9","issue":"1","first_page":"10604","last_page":"10604"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10324","display_name":"Microbial bioremediation and biosurfactants","score":0.9398999810218811,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10324","display_name":"Microbial bioremediation and biosurfactants","score":0.9398999810218811,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12078","display_name":"Environmental remediation with nanomaterials","score":0.02590000070631504,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.010499999858438969,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dehalococcoides-mccartyi","display_name":"Dehalococcoides mccartyi","score":0.9950000047683716},{"id":"https://openalex.org/keywords/reductive-dechlorination","display_name":"reductive dechlorination","score":0.9459999799728394},{"id":"https://openalex.org/keywords/reductive-dehalogenase","display_name":"reductive dehalogenase","score":0.9570000171661377},{"id":"https://openalex.org/keywords/chlorinated-ethenes","display_name":"chlorinated ethenes","score":0.8519999980926514},{"id":"https://openalex.org/keywords/groundwater-contamination","display_name":"groundwater contamination","score":0.9350000023841858},{"id":"https://openalex.org/keywords/targeted-proteomics","display_name":"targeted proteomics","score":0.8379999995231628},{"id":"https://openalex.org/keywords/protein-biomarkers","display_name":"protein biomarkers","score":0.7289999723434448},{"id":"https://openalex.org/keywords/tcea","display_name":"tceA","score":0.9739999771118164},{"id":"https://openalex.org/keywords/bioremediation-monitoring","display_name":"bioremediation monitoring","score":0.6539999842643738}],"concepts":[{"id":"https://openalex.org/C2777485300","wikidata":"https://www.wikidata.org/wiki/Q5252213","display_name":"Dehalogenase","level":3,"score":0.8161237239837646},{"id":"https://openalex.org/C2777568163","wikidata":"https://www.wikidata.org/wiki/Q1182938","display_name":"Dehalococcoides","level":5,"score":0.812972903251648},{"id":"https://openalex.org/C2777166327","wikidata":"https://www.wikidata.org/wiki/Q7306385","display_name":"Reductive dechlorination","level":3,"score":0.7595410346984863},{"id":"https://openalex.org/C46111723","wikidata":"https://www.wikidata.org/wiki/Q471857","display_name":"Proteomics","level":3,"score":0.48143336176872253},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.46240144968032837},{"id":"https://openalex.org/C2124996","wikidata":"https://www.wikidata.org/wiki/Q816441","display_name":"Bioremediation","level":3,"score":0.413720965385437},{"id":"https://openalex.org/C107872376","wikidata":"https://www.wikidata.org/wiki/Q321355","display_name":"Environmental chemistry","level":1,"score":0.35673877596855164},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3465201258659363},{"id":"https://openalex.org/C112570922","wikidata":"https://www.wikidata.org/wiki/Q60528603","display_name":"Contamination","level":2,"score":0.31107890605926514},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.244631826877594},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.22453299164772034},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.17721086740493774},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.09812834858894348},{"id":"https://openalex.org/C2781460079","wikidata":"https://www.wikidata.org/wiki/Q338869","display_name":"Vinyl chloride","level":4,"score":0.09545302391052246},{"id":"https://openalex.org/C15920480","wikidata":"https://www.wikidata.org/wiki/Q421281","display_name":"Copolymer","level":3,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000082942","descriptor_name":"Dehalococcoides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D001673","descriptor_name":"Biodegradation, Environmental","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006843","descriptor_name":"Hydrocarbons, Chlorinated","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014874","descriptor_name":"Water Pollutants, Chemical","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D041862","descriptor_name":"Chloroflexi","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D041862","descriptor_name":"Chloroflexi","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D041862","descriptor_name":"Chloroflexi","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D060587","descriptor_name":"Groundwater","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D060587","descriptor_name":"Groundwater","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1038/s41598-019-46901-6","doi":"https://doi.org/10.1038/s41598-019-46901-6","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-019-46901-6","pdf_url":"https://www.nature.com/articles/s41598-019-46901-6.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6646388","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6646388","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sci Rep","raw_type":"Text"},{"id":"pmid:31332202","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31332202","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific reports","raw_type":"Journal Article"},{"id":"pmh:oai:osti.gov:1545237","doi":null,"is_oa":true,"landing_page_url":"https://www.osti.gov/biblio/1545237","pdf_url":"https://www.osti.gov/servlets/purl/1545237","source":{"id":"https://openalex.org/S4306402487","display_name":"OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I139351228","host_organization_name":"Office of Scientific and Technical Information","host_organization_lineage":["https://openalex.org/I139351228"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"pmh:oai:doaj.org/article:13f88fac1e1142d39572b23259bd6bdc","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/13f88fac1e1142d39572b23259bd6bdc","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41598-019-46901-6","doi":"https://doi.org/10.1038/s41598-019-46901-6","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-019-46901-6","pdf_url":"https://www.nature.com/articles/s41598-019-46901-6.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/6","score":0.8999999761581421,"display_name":"Clean water and sanitation"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3678289167","display_name":null,"funder_award_id":"ER-2312","funder_id":"https://openalex.org/F4320333449","funder_display_name":"Strategic Environmental Research and Development Program"},{"id":"https://openalex.org/G7092688285","display_name":null,"funder_award_id":"ER-2312","funder_id":"https://openalex.org/F4320306078","funder_display_name":"U.S. Department of Defense"}],"funders":[{"id":"https://openalex.org/F4320306078","display_name":"U.S. Department of Defense","ror":"https://ror.org/0447fe631"},{"id":"https://openalex.org/F4320333449","display_name":"Strategic Environmental Research and Development Program","ror":"https://ror.org/00ew61678"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2964249043.pdf","grobid_xml":"https://content.openalex.org/works/W2964249043.grobid-xml"},"referenced_works_count":45,"referenced_works":["https://openalex.org/W1462298530","https://openalex.org/W1968115433","https://openalex.org/W1983601761","https://openalex.org/W1997938718","https://openalex.org/W2020248203","https://openalex.org/W2025531238","https://openalex.org/W2036089348","https://openalex.org/W2047069968","https://openalex.org/W2052822918","https://openalex.org/W2060578543","https://openalex.org/W2063186565","https://openalex.org/W2069184191","https://openalex.org/W2070303673","https://openalex.org/W2079471172","https://openalex.org/W2098680770","https://openalex.org/W2107710616","https://openalex.org/W2113610581","https://openalex.org/W2118190100","https://openalex.org/W2121310478","https://openalex.org/W2127647526","https://openalex.org/W2131990090","https://openalex.org/W2141606648","https://openalex.org/W2142176767","https://openalex.org/W2150102160","https://openalex.org/W2153549525","https://openalex.org/W2154360847","https://openalex.org/W2156705208","https://openalex.org/W2162602217","https://openalex.org/W2168999034","https://openalex.org/W2174111128","https://openalex.org/W2214850930","https://openalex.org/W2233551961","https://openalex.org/W2236569254","https://openalex.org/W2285483031","https://openalex.org/W2342696719","https://openalex.org/W2411886805","https://openalex.org/W2620926901","https://openalex.org/W2730255373","https://openalex.org/W2734214675","https://openalex.org/W2749079494","https://openalex.org/W2761314016","https://openalex.org/W2790137776","https://openalex.org/W2792546428","https://openalex.org/W2803405459","https://openalex.org/W4239998326"],"related_works":["https://openalex.org/W3009903350","https://openalex.org/W3212830265","https://openalex.org/W2127647526","https://openalex.org/W1994705876","https://openalex.org/W2069184191","https://openalex.org/W2036089348","https://openalex.org/W2090901484","https://openalex.org/W2075155653","https://openalex.org/W898032028","https://openalex.org/W4243351093"],"abstract_inverted_index":{"Dehalococcoides":[0],"mccartyi":[1],"(Dhc)":[2],"bacterial":[3,138],"strains":[4,93],"expressing":[5],"active":[6,153],"reductive":[7,122,167],"dehalogenase":[8],"(RDase)":[9],"enzymes":[10],"play":[11],"key":[12],"roles":[13],"in":[14,77,88,120,145],"the":[15,34,113,121,146,160],"transformation":[16],"and":[17,54,96,105,112,128,140,159,184],"detoxification":[18],"of":[19,36,91,132,148,162],"chlorinated":[20,23,81],"pollutants,":[21],"including":[22],"ethenes.":[24,82],"Site":[25],"monitoring":[26],"regimes":[27],"traditionally":[28],"rely":[29],"on":[30],"qPCR":[31],"to":[32,65,135,181],"assess":[33],"presence":[35],"Dhc":[37,74,92,156,190],"biomarker":[38],"genes;":[39],"however,":[40],"this":[41],"technique":[42],"alone":[43],"cannot":[44],"directly":[45],"inform":[46],"about":[47,189],"dechlorination":[48,61,76,123,154,168,191],"activity.":[49,192],"To":[50],"supplement":[51],"gene-centric":[52],"approaches":[53],"provide":[55,185],"a":[56,67,136],"more":[57],"reliable":[58],"proxy":[59],"for":[60],"activity,":[62],"we":[63],"sought":[64],"demonstrate":[66],"targeted":[68,133,176],"proteomics":[69,134,177],"approach":[70],"that":[71,175],"can":[72,178],"characterize":[73],"mediated":[75],"groundwater":[78,142,182],"contaminated":[79,141],"with":[80,155],"Targeted":[83],"peptide":[84],"selection":[85],"was":[86],"conducted":[87],"axenic":[89],"cultures":[90],"195,":[94],"FL2,":[95],"BAV1.":[97],"These":[98],"experiments":[99],"yielded":[100],"37":[101],"peptides":[102,164],"from":[103],"housekeeping":[104],"structural":[106],"proteins":[107,118],"(i.e.,":[108,125],"GroEL,":[109],"EF-TU,":[110],"rpL7/L2":[111],"S-layer),":[114],"as":[115,117],"well":[116],"involved":[119],"activity":[124],"FdhA,":[126],"TceA,":[127],"BvcA).":[129],"The":[130,170],"application":[131],"defined":[137],"consortium":[139],"samples":[143,183],"resulted":[144],"detection":[147,161],"FdhA":[149],"peptides,":[150],"which":[151],"revealed":[152],"strain-level":[157],"resolution,":[158],"RDases":[163],"indicating":[165],"specific":[166],"steps.":[169],"results":[171],"presented":[172],"here":[173],"show":[174],"be":[179],"applied":[180],"protein":[186],"level":[187],"information":[188]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-07-30T00:00:00"}