{"id":"https://openalex.org/W2964063310","doi":"https://doi.org/10.1111/ejn.14518","title":"Altered monoamine levels in the dorsal striatum of the rat are associated with alterations in behavioural selection and motivation following peripheral nerve injury and acute stress","display_name":"Altered monoamine levels in the dorsal striatum of the rat are associated with alterations in behavioural selection and motivation following peripheral nerve injury and acute stress","publication_year":2019,"publication_date":"2019-07-20","ids":{"openalex":"https://openalex.org/W2964063310","doi":"https://doi.org/10.1111/ejn.14518","mag":"2964063310","pmid":"https://pubmed.ncbi.nlm.nih.gov/31325375"},"language":"en","primary_location":{"id":"doi:10.1111/ejn.14518","doi":"https://doi.org/10.1111/ejn.14518","is_oa":false,"landing_page_url":"https://doi.org/10.1111/ejn.14518","pdf_url":null,"source":{"id":"https://openalex.org/S171130801","display_name":"European Journal of Neuroscience","issn_l":"0953-816X","issn":["0953-816X","1460-9568"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012621720","display_name":"Gizem Gemikonakli","orcid":"https://orcid.org/0000-0003-2594-7316","observed_orcids":["https://orcid.org/0000-0003-2594-7316"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Gizem Gemikonakli","raw_affiliation_strings":["Discipline of Anatomy & Histology School of Medical Sciences The University of Sydney Sydney New South Wales Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Discipline of Anatomy & Histology School of Medical Sciences The University of Sydney Sydney New South Wales Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022655473","display_name":"Kevin A. Keay","orcid":"https://orcid.org/0000-0003-3934-4380","observed_orcids":["https://orcid.org/0000-0003-3934-4380"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Kevin A. Keay","raw_affiliation_strings":["Discipline of Anatomy & Histology School of Medical Sciences The University of Sydney Sydney New South Wales Australia"],"raw_orcid":"https://orcid.org/0000-0003-3934-4380","affiliations":[{"raw_affiliation_string":"Discipline of Anatomy & Histology School of Medical Sciences The University of Sydney Sydney New South Wales Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003886260","display_name":"Michael D. Kendig","orcid":"https://orcid.org/0000-0003-3337-6402","observed_orcids":["https://orcid.org/0000-0003-3337-6402"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Michael D. Kendig","raw_affiliation_strings":["School of Psychology The University of Sydney Sydney New South Wales Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Psychology The University of Sydney Sydney New South Wales Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078088052","display_name":"James W.M. Kang","orcid":"https://orcid.org/0000-0002-8517-5656","observed_orcids":["https://orcid.org/0000-0002-8517-5656"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"James W. M. Kang","raw_affiliation_strings":["Discipline of Anatomy & Histology School of Medical Sciences The University of Sydney Sydney New South Wales Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Discipline of Anatomy & Histology School of Medical Sciences The University of Sydney Sydney New South Wales Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054573692","display_name":"Laura H. Corbit","orcid":"https://orcid.org/0000-0002-8356-0999","observed_orcids":["https://orcid.org/0000-0002-8356-0999"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["AU","CA"],"is_corresponding":false,"raw_author_name":"Laura H. Corbit","raw_affiliation_strings":["Department of Psychology The University of Toronto Toronto Ontario Canada","School of Psychology The University of Sydney Sydney New South Wales Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology The University of Toronto Toronto Ontario Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"School of Psychology The University of Sydney Sydney New South Wales Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103129478","display_name":"David Mor","orcid":"https://orcid.org/0000-0002-2201-3086","observed_orcids":["https://orcid.org/0000-0002-2201-3086"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"David Mor","raw_affiliation_strings":["Discipline of Anatomy & Histology School of Medical Sciences The University of Sydney Sydney New South Wales Australia"],"raw_orcid":"https://orcid.org/0000-0002-2201-3086","affiliations":[{"raw_affiliation_string":"Discipline of Anatomy & Histology School of Medical Sciences The University of Sydney Sydney New South Wales Australia","institution_ids":["https://openalex.org/I129604602"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5103129478"],"corresponding_institution_ids":["https://openalex.org/I129604602"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.6085,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.60115892,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"50","issue":"5","first_page":"2786","last_page":"2800"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.8809000253677368,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.8809000253677368,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10042","display_name":"Neural and Behavioral Psychology Studies","score":0.03269999846816063,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.021299999207258224,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dorsal-striatum","display_name":"dorsal striatum","score":0.8889999985694885},{"id":"https://openalex.org/keywords/dorsomedial-striatum","display_name":"dorsomedial striatum","score":0.7950000166893005},{"id":"https://openalex.org/keywords/dorsolateral-striatum","display_name":"dorsolateral striatum","score":1.0},{"id":"https://openalex.org/keywords/monoamines","display_name":"monoamines","score":0.7720000147819519},{"id":"https://openalex.org/keywords/chronic-constriction-injury","display_name":"chronic constriction injury","score":0.703000009059906},{"id":"https://openalex.org/keywords/sciatic-nerve-injury","display_name":"sciatic nerve injury","score":0.7429999709129333},{"id":"https://openalex.org/keywords/neuropathic-pain","display_name":"neuropathic pain","score":0.9610000252723694},{"id":"https://openalex.org/keywords/acute-stress","display_name":"acute stress","score":0.7639999985694885},{"id":"https://openalex.org/keywords/restraint-stress","display_name":"restraint stress","score":0.9129999876022339},{"id":"https://openalex.org/keywords/behavioral-flexibility","display_name":"behavioral flexibility","score":0.9610000252723694},{"id":"https://openalex.org/keywords/outcome-devaluation","display_name":"outcome devaluation","score":0.9160000085830688},{"id":"https://openalex.org/keywords/goal-directed-behavior","display_name":"goal-directed behavior","score":0.7509999871253967},{"id":"https://openalex.org/keywords/norepinephrine","display_name":"norepinephrine","score":0.7459999918937683},{"id":"https://openalex.org/keywords/serotonin","display_name":"serotonin","score":0.9739999771118164},{"id":"https://openalex.org/keywords/dopamine","display_name":"dopamine","score":0.9929999709129333},{"id":"https://openalex.org/keywords/hemispheric-asymmetry","display_name":"hemispheric lateralization","score":0.8059999942779541},{"id":"https://openalex.org/keywords/individual-differences","display_name":"individual differences","score":0.6510000228881836}],"concepts":[{"id":"https://openalex.org/C137183658","wikidata":"https://www.wikidata.org/wiki/Q461076","display_name":"Dopaminergic","level":3,"score":0.7556002140045166},{"id":"https://openalex.org/C187714386","wikidata":"https://www.wikidata.org/wiki/Q420225","display_name":"Monoamine neurotransmitter","level":4,"score":0.6014038324356079},{"id":"https://openalex.org/C42251903","wikidata":"https://www.wikidata.org/wiki/Q18391002","display_name":"Monoaminergic","level":4,"score":0.5774095058441162},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5707231760025024},{"id":"https://openalex.org/C2777107010","wikidata":"https://www.wikidata.org/wiki/Q2798704","display_name":"Neuropathic pain","level":2,"score":0.5626991987228394},{"id":"https://openalex.org/C37000724","wikidata":"https://www.wikidata.org/wiki/Q50430226","display_name":"Serotonergic","level":4,"score":0.5287284851074219},{"id":"https://openalex.org/C2780062018","wikidata":"https://www.wikidata.org/wiki/Q1319792","display_name":"Striatum","level":3,"score":0.5144941806793213},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.4876898527145386},{"id":"https://openalex.org/C79840881","wikidata":"https://www.wikidata.org/wiki/Q1080497","display_name":"Lateralization of brain function","level":2,"score":0.45183998346328735},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.44620248675346375},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36966946721076965},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3320254683494568},{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.2695140838623047},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.09301796555519104}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001522","descriptor_name":"Behavior, Animal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003342","descriptor_name":"Corpus Striatum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004298","descriptor_name":"Dopamine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009042","descriptor_name":"Motivation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009638","descriptor_name":"Norepinephrine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012701","descriptor_name":"Serotonin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013315","descriptor_name":"Stress, Psychological","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059348","descriptor_name":"Peripheral Nerve Injuries","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1111/ejn.14518","doi":"https://doi.org/10.1111/ejn.14518","is_oa":false,"landing_page_url":"https://doi.org/10.1111/ejn.14518","pdf_url":null,"source":{"id":"https://openalex.org/S171130801","display_name":"European Journal of Neuroscience","issn_l":"0953-816X","issn":["0953-816X","1460-9568"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Neuroscience","raw_type":"journal-article"},{"id":"pmid:31325375","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31325375","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The European journal of neuroscience","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":65,"referenced_works":["https://openalex.org/W1558670112","https://openalex.org/W1573561879","https://openalex.org/W1862521538","https://openalex.org/W1879409027","https://openalex.org/W1964812893","https://openalex.org/W1966724162","https://openalex.org/W1967677380","https://openalex.org/W1969977458","https://openalex.org/W1975401347","https://openalex.org/W1979885081","https://openalex.org/W1981739486","https://openalex.org/W1985367358","https://openalex.org/W1991028421","https://openalex.org/W1993631201","https://openalex.org/W1993795917","https://openalex.org/W1995411317","https://openalex.org/W1997221050","https://openalex.org/W1997987765","https://openalex.org/W2002047798","https://openalex.org/W2002982428","https://openalex.org/W2005815231","https://openalex.org/W2005962945","https://openalex.org/W2007129325","https://openalex.org/W2010570008","https://openalex.org/W2010776065","https://openalex.org/W2012571406","https://openalex.org/W2013991005","https://openalex.org/W2019535443","https://openalex.org/W2021745579","https://openalex.org/W2021963844","https://openalex.org/W2025797408","https://openalex.org/W2039129771","https://openalex.org/W2043606223","https://openalex.org/W2056061278","https://openalex.org/W2056552590","https://openalex.org/W2066306677","https://openalex.org/W2068721994","https://openalex.org/W2078308586","https://openalex.org/W2079467356","https://openalex.org/W2080935562","https://openalex.org/W2081845928","https://openalex.org/W2085553767","https://openalex.org/W2085735515","https://openalex.org/W2087454739","https://openalex.org/W2090882423","https://openalex.org/W2098615765","https://openalex.org/W2099592975","https://openalex.org/W2102754843","https://openalex.org/W2112337921","https://openalex.org/W2113226190","https://openalex.org/W2113679854","https://openalex.org/W2114520249","https://openalex.org/W2122163450","https://openalex.org/W2133191097","https://openalex.org/W2150825904","https://openalex.org/W2155771253","https://openalex.org/W2162580191","https://openalex.org/W2162773102","https://openalex.org/W2168189344","https://openalex.org/W2172567489","https://openalex.org/W2180704326","https://openalex.org/W2260907218","https://openalex.org/W2335672482","https://openalex.org/W2607248352","https://openalex.org/W2751940187"],"related_works":["https://openalex.org/W4327909798","https://openalex.org/W2607248352","https://openalex.org/W2064537885","https://openalex.org/W2388058562","https://openalex.org/W7084295710","https://openalex.org/W7129574930","https://openalex.org/W1879409027","https://openalex.org/W3109819398","https://openalex.org/W2754600391","https://openalex.org/W2041664592"],"abstract_inverted_index":{"Chronic":[0],"neuropathic":[1],"pain":[2,62,211],"and":[3,20,34,49,54,98,107,119,129,186,242],"psychological":[4,15,55,208],"stress":[5,56,79,209],"interact":[6],"to":[7,139,240,244],"compromise":[8],"goal-directed":[9,33],"control":[10],"over":[11],"behaviour":[12],"following":[13,51,161,207,228],"mild":[14],"stress.":[16],"The":[17,223],"dorsomedial":[18],"(DMS)":[19],"dorsolateral":[21],"(DLS)":[22],"striatum":[23],"in":[24,43,46,75,116,122,149,153,158,168,178],"the":[25,30,47,72,91,105,117,123,127,150,154,169,179,195,198,220,229],"rat":[26],"are":[27],"crucial":[28],"for":[29],"expression":[31],"of":[32,71,125,184,197,225],"habitual":[35],"behaviours,":[36],"respectively.":[37],"This":[38],"study":[39],"investigated":[40],"whether":[41],"changes":[42],"monoamine":[44],"levels":[45],"DMS":[48,128,151,243],"DLS":[50,106,245],"nerve":[52,74],"injury":[53,69],"reflect":[57],"these":[58,176],"behavioural":[59,159,189,205,226],"differences.":[60],"Neuropathic":[61],"was":[63,80,88,192],"induced":[64,81],"by":[65],"a":[66,83,132,140,146,215,236],"chronic":[67],"constriction":[68],"(CCI)":[70],"sciatic":[73],"Sprague-Dawley":[76],"rats.":[77],"Acute":[78],"using":[82,90],"15-min":[84],"restraint.":[85],"Behavioural":[86],"flexibility":[87,160,206,227],"assessed":[89],"outcome":[92],"devaluation":[93],"paradigm.":[94],"Noradrenaline,":[95],"serotonin,":[96],"dopamine":[97],"associated":[99,193,213,234],"metabolites":[100],"were":[101],"measured":[102],"bilaterally":[103],"from":[104,238],"DMS.":[108,181],"In":[109],"uninjured":[110],"rats,":[111],"restraint":[112,187],"increased":[113],"dopaminergic":[114,166],"markers":[115,121,167,177],"left":[118,134,180,216,239],"serotonergic":[120],"right":[124,170],"both":[126],"DLS,":[130,171],"indicating":[131],"possible":[133],"hemisphere-mediated":[135],"dominance.":[136,200,246],"CCI":[137,162,185],"led":[138],"slightly":[141],"different":[142],"lateralised":[143],"effect,":[144],"with":[145,165,175,194,214,235],"larger":[147],"effect":[148],"than":[152],"DLS.":[155],"Individual":[156],"differences":[157],"negatively":[163],"correlated":[164,174],"but":[172],"positively":[173],"A":[182],"combination":[183],"reduced":[188],"flexibility,":[190],"which":[191],"loss":[196,224],"left/DMS":[199],"These":[201],"data":[202],"suggest":[203],"that":[204],"or":[210],"is":[212,232],"hemisphere":[217],"dominance":[218],"within":[219],"dorsal":[221],"striatum.":[222],"combined":[230],"stressors":[231],"then":[233],"transition":[237],"right,":[241]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-07-30T00:00:00"}