{"id":"https://openalex.org/W2963777281","doi":"https://doi.org/10.1371/journal.pone.0219769","title":"A model of functional thyroid disease status over the lifetime","display_name":"A model of functional thyroid disease status over the lifetime","publication_year":2019,"publication_date":"2019-07-18","ids":{"openalex":"https://openalex.org/W2963777281","doi":"https://doi.org/10.1371/journal.pone.0219769","mag":"2963777281","pmid":"https://pubmed.ncbi.nlm.nih.gov/31318913","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6638952"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0219769","doi":"https://doi.org/10.1371/journal.pone.0219769","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0219769","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0219769&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0219769&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021936943","display_name":"Michael W. Dzierlenga","orcid":"https://orcid.org/0000-0001-7010-6191","observed_orcids":["https://orcid.org/0000-0001-7010-6191"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Michael W. Dzierlenga","raw_affiliation_strings":["ScitoVation, Research Triangle Park, North Carolina, United States of America"],"raw_orcid":"https://orcid.org/0000-0001-7010-6191","affiliations":[{"raw_affiliation_string":"ScitoVation, Research Triangle Park, North Carolina, United States of America","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052101010","display_name":"Bruce C. Allen","orcid":"https://orcid.org/0000-0003-1450-3955","observed_orcids":["https://orcid.org/0000-0003-1450-3955"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bruce C. Allen","raw_affiliation_strings":["Independent Consultant, Chapel Hill, North Carolina, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Independent Consultant, Chapel Hill, North Carolina, United States of America","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113835540","display_name":"Peyton L. Ward","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peyton L. Ward","raw_affiliation_strings":["Ramboll, Research Triangle Park, North Carolina, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ramboll, Research Triangle Park, North Carolina, United States of America","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002591537","display_name":"Harvey J. Clewell III M.A.","orcid":"https://orcid.org/0000-0002-2253-9045","observed_orcids":["https://orcid.org/0000-0002-2253-9045"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Harvey J. Clewell","raw_affiliation_strings":["Ramboll, Research Triangle Park, North Carolina, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ramboll, Research Triangle Park, North Carolina, United States of America","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090383900","display_name":"Matthew P. Longnecker","orcid":"https://orcid.org/0000-0001-6073-5322","observed_orcids":["https://orcid.org/0000-0001-6073-5322"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Matthew P. Longnecker","raw_affiliation_strings":["Ramboll, Research Triangle Park, North Carolina, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ramboll, Research Triangle Park, North Carolina, United States of America","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5021936943"],"corresponding_institution_ids":[],"apc_list":{"value":1595,"currency":"USD","value_usd":1595},"apc_paid":{"value":1595,"currency":"USD","value_usd":1595},"fwci":1.2172,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.80588716,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"14","issue":"7","first_page":"e0219769","last_page":"e0219769"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11728","display_name":"Thyroid and Parathyroid Surgery","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10329","display_name":"Thyroid Cancer Diagnosis and Treatment","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/natural-history-of-disease","display_name":"natural history of disease","score":0.8479999899864197},{"id":"https://openalex.org/keywords/markov-chain-model","display_name":"Markov chain model","score":0.9750000238418579},{"id":"https://openalex.org/keywords/subclinical-hypothyroidism","display_name":"subclinical hypothyroidism","score":0.8679999709129333},{"id":"https://openalex.org/keywords/overt-hypothyroidism","display_name":"overt hypothyroidism","score":0.9869999885559082},{"id":"https://openalex.org/keywords/subclinical-hyperthyroidism","display_name":"subclinical hyperthyroidism","score":0.9580000042915344},{"id":"https://openalex.org/keywords/overt-hyperthyroidism","display_name":"overt hyperthyroidism","score":0.9900000095367432},{"id":"https://openalex.org/keywords/thyroid-disease-prevalence","display_name":"thyroid disease prevalence","score":0.7250000238418579},{"id":"https://openalex.org/keywords/thyroid-disease-incidence","display_name":"thyroid disease incidence","score":0.8379999995231628},{"id":"https://openalex.org/keywords/iodine-intake","display_name":"iodine intake","score":0.9110000133514404},{"id":"https://openalex.org/keywords/bayesian-parameter-estimation","display_name":"Bayesian parameter estimation","score":0.49900001287460327},{"id":"https://openalex.org/keywords/population-simulation","display_name":"population simulation","score":0.5130000114440918},{"id":"https://openalex.org/keywords/quantitative-bias-analysis","display_name":"quantitative bias analysis","score":0.6880000233650208},{"id":"https://openalex.org/keywords/environmental-contaminants","display_name":"environmental pollutants","score":0.7559999823570251}],"concepts":[{"id":"https://openalex.org/C2780176905","wikidata":"https://www.wikidata.org/wiki/Q6673122","display_name":"Thyroid disease","level":3,"score":0.7761656045913696},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6703945994377136},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6428008675575256},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.6378976106643677},{"id":"https://openalex.org/C113280763","wikidata":"https://www.wikidata.org/wiki/Q2326546","display_name":"Subclinical infection","level":2,"score":0.6361619234085083},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.538877546787262},{"id":"https://openalex.org/C2993291352","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid function","level":3,"score":0.4747731387615204},{"id":"https://openalex.org/C2779874844","wikidata":"https://www.wikidata.org/wiki/Q1967281","display_name":"National Health and Nutrition Examination Survey","level":3,"score":0.4635791778564453},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.408665269613266},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.34286758303642273},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.33743613958358765},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.20546647906303406},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.1709183156490326},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1499047875404358},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008390","descriptor_name":"Markov Chains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011336","descriptor_name":"Probability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013959","descriptor_name":"Thyroid Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D013959","descriptor_name":"Thyroid Diseases","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D013959","descriptor_name":"Thyroid Diseases","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D016013","descriptor_name":"Likelihood Functions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035501","descriptor_name":"Uncertainty","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1371/journal.pone.0219769","doi":"https://doi.org/10.1371/journal.pone.0219769","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0219769","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0219769&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6638952","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6638952","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmid:31318913","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31318913","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:RePEc:plo:pone00:0219769","doi":null,"is_oa":false,"landing_page_url":"https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0219769","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:7982d25cf9b14690a3baffac9d5a42ac","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/7982d25cf9b14690a3baffac9d5a42ac","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 14, Iss 7, p e0219769 (2019)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/8955182","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/A_model_of_functional_thyroid_disease_status_over_the_lifetime/8955182","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0219769","doi":"https://doi.org/10.1371/journal.pone.0219769","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0219769","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0219769&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320307785","display_name":"3M","ror":"https://ror.org/00mgss748"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2963777281.pdf","grobid_xml":"https://content.openalex.org/works/W2963777281.grobid-xml"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W174924810","https://openalex.org/W1562308323","https://openalex.org/W1979738094","https://openalex.org/W1983622907","https://openalex.org/W1984273763","https://openalex.org/W1990558017","https://openalex.org/W1994306309","https://openalex.org/W2018857232","https://openalex.org/W2023374432","https://openalex.org/W2025817299","https://openalex.org/W2026270187","https://openalex.org/W2026393296","https://openalex.org/W2031519196","https://openalex.org/W2037555696","https://openalex.org/W2038962818","https://openalex.org/W2045656233","https://openalex.org/W2059985338","https://openalex.org/W2082697749","https://openalex.org/W2085643661","https://openalex.org/W2086128493","https://openalex.org/W2096234151","https://openalex.org/W2102545047","https://openalex.org/W2105144837","https://openalex.org/W2109476150","https://openalex.org/W2116587748","https://openalex.org/W2117623117","https://openalex.org/W2118758311","https://openalex.org/W2119019874","https://openalex.org/W2133547068","https://openalex.org/W2140936682","https://openalex.org/W2146767477","https://openalex.org/W2147034580","https://openalex.org/W2147374444","https://openalex.org/W2157413484","https://openalex.org/W2159765367","https://openalex.org/W2159788755","https://openalex.org/W2163040576","https://openalex.org/W2168406714","https://openalex.org/W2520387346","https://openalex.org/W2530107877","https://openalex.org/W2560379484","https://openalex.org/W2582743722","https://openalex.org/W2801528100","https://openalex.org/W2806839461","https://openalex.org/W2809950652","https://openalex.org/W2986816748","https://openalex.org/W3022564440","https://openalex.org/W4234098531","https://openalex.org/W4237240896"],"related_works":["https://openalex.org/W7161755246","https://openalex.org/W3162563014","https://openalex.org/W2148501322","https://openalex.org/W2115426825","https://openalex.org/W2147374444","https://openalex.org/W4386950914","https://openalex.org/W2028530739","https://openalex.org/W2769678734","https://openalex.org/W2900708221","https://openalex.org/W7130552349"],"abstract_inverted_index":{"Mathematical":[0],"models":[1],"of":[2,6,19,27,35,47,90,114,153,165,183,224,264,271,277],"the":[3,41,125,141,162,174,180,231,234,250],"natural":[4],"history":[5],"disease":[7,38,50,66,94,147,170,185,227,247,273],"can":[8],"predict":[9],"incidence":[10,181,228],"rates":[11,182,229],"based":[12,102,123,212],"on":[13,103,124,213],"prevalence":[14,121,143,164,242],"data":[15,105,122,144,243,267],"and":[16,72,106,128,151,173,207,221,244],"support":[17],"simulations":[18],"populations":[20],"where":[21],"thyroid":[22,37,49,65,76,169,226,246,272],"function":[23],"affects":[24],"other":[25],"aspects":[26],"physiology.":[28],"We":[29,78],"developed":[30],"a":[31,80,137,198,237],"Markov":[32],"chain":[33],"model":[34,85,135,189,218,235],"functional":[36,225],"status":[39,248],"over":[40,249],"lifetime.":[42],"Subjects":[43],"were":[44,101,117,196,208],"in":[45,56],"one":[46],"seven":[48],"states":[51],"at":[52],"any":[53],"given":[54],"point":[55],"their":[57],"lives":[58],"[normal,":[59],"subclinical":[60,68],"hypothyroidism,":[61,63],"overt":[62,70],"treated":[64,168,184],"(ever),":[67],"hyperthyroidism,":[69,71],"reverted":[73],"to":[74,83,96,119,140,204,240],"normal":[75],"status].":[77],"used":[79],"Bayesian":[81],"approach":[82],"fitting":[84],"parameters.":[86],"A":[87],"priori":[88],"probabilities":[89,113],"changing":[91,115],"from":[92,187],"each":[93,146],"state":[95,116],"another":[97],"per":[98],"unit":[99],"time":[100],"published":[104,191],"summarized":[107],"using":[108],"meta-analysis,":[109],"when":[110],"possible.":[111],"The":[112,133,201,217],"fitted":[118,134],"observed":[120,142,163],"National":[126],"Health":[127],"Nutrition":[129],"Examination":[130],"Survey":[131],"2007-2012.":[132],"provided":[136,219],"satisfactory":[138],"fit":[139,239],"for":[145,157,230,255],"state,":[148],"by":[149],"sex":[150],"decade":[152],"age.":[154],"For":[155],"example,":[156],"males":[158],"50-59":[159],"years":[160],"old,":[161],"ever":[166],"having":[167],"was":[171,177],"4.4%":[172],"predicted":[175,186],"value":[176],"4.6%.":[178],"Comparing":[179],"our":[188],"with":[190,210,274],"values":[192],"revealed":[193],"that":[194],"82%":[195],"within":[197],"4-fold":[199],"difference.":[200],"differences":[202],"seemed":[203],"be":[205],"systematic":[206],"consistent":[209],"expectation":[211],"national":[214,241],"iodine":[215],"intakes.":[216],"new":[220],"comprehensive":[222],"estimates":[223],"U.S.":[232],"Because":[233],"provides":[236],"reasonable":[238],"predicts":[245],"lifetime,":[251],"it":[252],"is":[253],"suitable":[254],"simulating":[256],"populations,":[257],"thereby":[258],"making":[259],"possible":[260],"quantitative":[261],"bias":[262],"analyses":[263],"selected":[265],"epidemiologic":[266],"reporting":[268],"an":[269],"association":[270],"serum":[275],"concentrations":[276],"environmental":[278],"contaminants.":[279]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-07-30T00:00:00"}