{"id":"https://openalex.org/W2963476189","doi":"https://doi.org/10.2172/1543199","title":"Development of a Sustainable Green Chemistry Platform for Production of Acetone and Downstream Drop-in Fuel and Commodity Products Directly From Biomass Syngas Via a Novel Energy Conserving Route in Engineered Acetogenic Bacteria","display_name":"Development of a Sustainable Green Chemistry Platform for Production of Acetone and Downstream Drop-in Fuel and Commodity Products Directly From Biomass Syngas Via a Novel Energy Conserving Route in Engineered Acetogenic Bacteria","publication_year":2019,"publication_date":"2019-06-05","ids":{"openalex":"https://openalex.org/W2963476189","doi":"https://doi.org/10.2172/1543199","mag":"2963476189"},"language":"en","primary_location":{"id":"doi:10.2172/1543199","doi":"https://doi.org/10.2172/1543199","is_oa":false,"landing_page_url":"https://doi.org/10.2172/1543199","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oak Ridge National Laboratory (ORNL)","raw_type":"report"},"volume":null,"type":"report","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.osti.gov/servlets/purl/1543199","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089517241","display_name":"Timothy James Tschaplinski","orcid":"https://orcid.org/0000-0002-9540-6622","observed_orcids":["https://orcid.org/0000-0002-9540-6622"]},"institutions":[{"id":"https://openalex.org/I1289243028","display_name":"Oak Ridge National Laboratory","ror":"https://ror.org/01qz5mb56","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289243028","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I4210159294"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy Tschaplinski","raw_affiliation_strings":["Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)"],"raw_orcid":"https://orcid.org/0000-0002-9540-6622","affiliations":[{"raw_affiliation_string":"Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)","institution_ids":["https://openalex.org/I1289243028"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033023534","display_name":"Payal Charania","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I75027704","display_name":"University of Tennessee at Knoxville","ror":"https://ror.org/020f3ap87","country_code":"US","type":"education","lineage":["https://openalex.org/I75027704"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Payal Charania","raw_affiliation_strings":["Univ. of Tennessee, Knoxville, TN (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of Tennessee, Knoxville, TN (United States)","institution_ids":["https://openalex.org/I75027704"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036135416","display_name":"Nancy L. Engle","orcid":"https://orcid.org/0000-0003-0290-7987","observed_orcids":["https://orcid.org/0000-0003-0290-7987"]},"institutions":[{"id":"https://openalex.org/I1289243028","display_name":"Oak Ridge National Laboratory","ror":"https://ror.org/01qz5mb56","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289243028","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I4210159294"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nancy Engle","raw_affiliation_strings":["Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)"],"raw_orcid":"https://orcid.org/0000-0003-0290-7987","affiliations":[{"raw_affiliation_string":"Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)","institution_ids":["https://openalex.org/I1289243028"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022944441","display_name":"Richard J. Giannone","orcid":"https://orcid.org/0000-0001-8551-0138","observed_orcids":["https://orcid.org/0000-0001-8551-0138"]},"institutions":[{"id":"https://openalex.org/I1289243028","display_name":"Oak Ridge National Laboratory","ror":"https://ror.org/01qz5mb56","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289243028","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I4210159294"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard Giannone","raw_affiliation_strings":["Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)"],"raw_orcid":"https://orcid.org/0000-0001-8551-0138","affiliations":[{"raw_affiliation_string":"Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)","institution_ids":["https://openalex.org/I1289243028"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002596998","display_name":"Robert L. Hettich","orcid":"https://orcid.org/0000-0001-7708-786X","observed_orcids":["https://orcid.org/0000-0001-7708-786X"]},"institutions":[{"id":"https://openalex.org/I1289243028","display_name":"Oak Ridge National Laboratory","ror":"https://ror.org/01qz5mb56","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289243028","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I4210159294"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert (Bob) Hettich","raw_affiliation_strings":["Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)"],"raw_orcid":"https://orcid.org/0000-0001-7708-786X","affiliations":[{"raw_affiliation_string":"Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)","institution_ids":["https://openalex.org/I1289243028"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002003335","display_name":"Dawn M. Klingeman","orcid":"https://orcid.org/0000-0002-4307-2560","observed_orcids":["https://orcid.org/0000-0002-4307-2560"]},"institutions":[{"id":"https://openalex.org/I1289243028","display_name":"Oak Ridge National Laboratory","ror":"https://ror.org/01qz5mb56","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289243028","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I4210159294"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dawn Klingeman","raw_affiliation_strings":["Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)"],"raw_orcid":"https://orcid.org/0000-0002-4307-2560","affiliations":[{"raw_affiliation_string":"Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)","institution_ids":["https://openalex.org/I1289243028"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046377901","display_name":"Suresh Poudel","orcid":"https://orcid.org/0000-0003-2333-3556","observed_orcids":["https://orcid.org/0000-0003-2333-3556"]},"institutions":[{"id":"https://openalex.org/I1289243028","display_name":"Oak Ridge National Laboratory","ror":"https://ror.org/01qz5mb56","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289243028","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I4210159294"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Suresh Poudel","raw_affiliation_strings":["Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)","institution_ids":["https://openalex.org/I1289243028"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108456341","display_name":"Zamin Koo Yang","orcid":"https://orcid.org/0009-0000-1556-9601","observed_orcids":["https://orcid.org/0009-0000-1556-9601"]},"institutions":[{"id":"https://openalex.org/I1289243028","display_name":"Oak Ridge National Laboratory","ror":"https://ror.org/01qz5mb56","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289243028","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I4210159294"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zamin Yang","raw_affiliation_strings":["Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)","institution_ids":["https://openalex.org/I1289243028"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021654825","display_name":"S\u00e9an Dennis Simpson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sean Simpson","raw_affiliation_strings":["LanzaTech, Skokie, IL (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LanzaTech, Skokie, IL (United States)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024328523","display_name":"Tanus Abdalla","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tanus Abdalla","raw_affiliation_strings":["LanzaTech, Skokie, IL (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LanzaTech, Skokie, IL (United States)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019407143","display_name":"Steven D. Brown","orcid":"https://orcid.org/0000-0002-9281-3898","observed_orcids":["https://orcid.org/0000-0002-9281-3898"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Steven Brown","raw_affiliation_strings":["LanzaTech, Skokie, IL (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LanzaTech, Skokie, IL (United States)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047961772","display_name":"Christina E. Canter","orcid":"https://orcid.org/0000-0003-2515-4869","observed_orcids":["https://orcid.org/0000-0003-2515-4869"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christina Canter","raw_affiliation_strings":["LanzaTech, Skokie, IL (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LanzaTech, Skokie, IL (United States)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031398414","display_name":"Robert J. Conrado","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert Conrado","raw_affiliation_strings":["LanzaTech, Skokie, IL (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LanzaTech, Skokie, IL (United States)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009421497","display_name":"James Daniell","orcid":"https://orcid.org/0000-0003-0831-4349","observed_orcids":["https://orcid.org/0000-0003-0831-4349"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"James Daniell","raw_affiliation_strings":["LanzaTech, Skokie, IL (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LanzaTech, Skokie, IL (United States)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002959825","display_name":"Asela Dassanayake","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Asela Dassanayake","raw_affiliation_strings":["LanzaTech, Skokie, IL (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LanzaTech, Skokie, IL (United States)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011898539","display_name":"Allan Haiming Gao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Allan Gao","raw_affiliation_strings":["LanzaTech, Skokie, IL (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LanzaTech, Skokie, IL (United States)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110166252","display_name":"Rasmus O. Jensen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rasmus Jensen","raw_affiliation_strings":["LanzaTech, Skokie, IL (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LanzaTech, Skokie, IL (United States)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088298377","display_name":"Michael K\u00f6epke","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael K\u00f6epke","raw_affiliation_strings":["LanzaTech, Skokie, IL (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LanzaTech, Skokie, IL (United States)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061626828","display_name":"Ching Leang","orcid":"https://orcid.org/0000-0001-8694-5504","observed_orcids":["https://orcid.org/0000-0001-8694-5504"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ching Leang","raw_affiliation_strings":["LanzaTech, Skokie, IL (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LanzaTech, Skokie, IL (United States)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040676563","display_name":"Fungmin Eric Liew","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"FungMin (Eric) Liew","raw_affiliation_strings":["LanzaTech, Skokie, IL (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LanzaTech, Skokie, IL (United States)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103269798","display_name":"Shilpa Nagaraju","orcid":"https://orcid.org/0000-0003-3114-6056","observed_orcids":["https://orcid.org/0000-0003-3114-6056"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shilpa Nagaraju","raw_affiliation_strings":["LanzaTech, Skokie, IL (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LanzaTech, Skokie, IL (United States)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024075831","display_name":"Robert Nogle","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert Nogle","raw_affiliation_strings":["LanzaTech, Skokie, IL (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LanzaTech, Skokie, IL (United States)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076238370","display_name":"Ryan C. Tappel","orcid":"https://orcid.org/0000-0002-7735-1226","observed_orcids":["https://orcid.org/0000-0002-7735-1226"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ryan Tappel","raw_affiliation_strings":["LanzaTech, Skokie, IL (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LanzaTech, Skokie, IL (United States)","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067287118","display_name":"Loan Tran","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Loan Tran","raw_affiliation_strings":["LanzaTech, Skokie, IL (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LanzaTech, Skokie, IL (United States)","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":12,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10171","display_name":"Biofuel production and bioconversion","score":0.007199999876320362,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10284","display_name":"Anaerobic Digestion and Biogas Production","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2215","display_name":"Building and Construction"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acetone-production","display_name":"acetone production","score":0.9900000095367432},{"id":"https://openalex.org/keywords/biomass-syngas","display_name":"biomass syngas","score":0.972000002861023},{"id":"https://openalex.org/keywords/drop-in-fuels","display_name":"drop-in fuels","score":0.8610000014305115},{"id":"https://openalex.org/keywords/commodity-chemicals","display_name":"commodity chemicals","score":0.8050000071525574},{"id":"https://openalex.org/keywords/beta-hydroxybutyrate","display_name":"beta-hydroxybutyrate","score":0.9980000257492065},{"id":"https://openalex.org/keywords/genome-mining","display_name":"genome mining","score":0.5580000281333923},{"id":"https://openalex.org/keywords/enzyme-engineering","display_name":"enzyme engineering","score":0.6430000066757202},{"id":"https://openalex.org/keywords/continuous-fermentation","display_name":"continuous fermentation","score":0.3959999978542328},{"id":"https://openalex.org/keywords/process-scale-up","display_name":"process scale-up","score":0.675000011920929},{"id":"https://openalex.org/keywords/non-food-biomass","display_name":"non-food biomass","score":0.6200000047683716},{"id":"https://openalex.org/keywords/green-chemistry","display_name":"green chemistry","score":0.5730000138282776},{"id":"https://openalex.org/keywords/greenhouse-gas-emissions-reduction","display_name":"greenhouse gas emissions reduction","score":0.5659999847412109},{"id":"https://openalex.org/keywords/techno-economic-analysis","display_name":"techno-economic analysis","score":0.5450000166893005}],"concepts":[{"id":"https://openalex.org/C2781213060","wikidata":"https://www.wikidata.org/wiki/Q49546","display_name":"Acetone","level":2,"score":0.6300762891769409},{"id":"https://openalex.org/C2779227428","wikidata":"https://www.wikidata.org/wiki/Q4915219","display_name":"Bioproduction","level":2,"score":0.6117511987686157},{"id":"https://openalex.org/C179720865","wikidata":"https://www.wikidata.org/wiki/Q1550480","display_name":"Commodity chemicals","level":3,"score":0.5868100523948669},{"id":"https://openalex.org/C67568554","wikidata":"https://www.wikidata.org/wiki/Q385442","display_name":"Downstream processing","level":2,"score":0.5366595983505249},{"id":"https://openalex.org/C115540264","wikidata":"https://www.wikidata.org/wiki/Q2945560","display_name":"Biomass (ecology)","level":2,"score":0.5301728248596191},{"id":"https://openalex.org/C2780301381","wikidata":"https://www.wikidata.org/wiki/Q864683","display_name":"Biorefinery","level":3,"score":0.47513845562934875},{"id":"https://openalex.org/C53991642","wikidata":"https://www.wikidata.org/wiki/Q128991","display_name":"Biofuel","level":2,"score":0.47172990441322327},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.47084495425224304},{"id":"https://openalex.org/C194439259","wikidata":"https://www.wikidata.org/wiki/Q3273339","display_name":"Syngas","level":3,"score":0.4528525471687317},{"id":"https://openalex.org/C548081761","wikidata":"https://www.wikidata.org/wiki/Q180388","display_name":"Waste management","level":1,"score":0.3897145986557007},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.18322396278381348},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.10135588049888611},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.0},{"id":"https://openalex.org/C512968161","wikidata":"https://www.wikidata.org/wiki/Q556","display_name":"Hydrogen","level":2,"score":0.0},{"id":"https://openalex.org/C111368507","wikidata":"https://www.wikidata.org/wiki/Q43518","display_name":"Oceanography","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.2172/1543199","doi":"https://doi.org/10.2172/1543199","is_oa":false,"landing_page_url":"https://doi.org/10.2172/1543199","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oak Ridge National Laboratory (ORNL)","raw_type":"report"},{"id":"pmh:oai:osti.gov:1543199","doi":null,"is_oa":true,"landing_page_url":"https://www.osti.gov/biblio/1543199","pdf_url":"https://www.osti.gov/servlets/purl/1543199","source":{"id":"https://openalex.org/S4306402487","display_name":"OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I139351228","host_organization_name":"Office of Scientific and Technical Information","host_organization_lineage":["https://openalex.org/I139351228"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:osti.gov:1543199","doi":null,"is_oa":true,"landing_page_url":"https://www.osti.gov/biblio/1543199","pdf_url":"https://www.osti.gov/servlets/purl/1543199","source":{"id":"https://openalex.org/S4306402487","display_name":"OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I139351228","host_organization_name":"Office of Scientific and Technical Information","host_organization_lineage":["https://openalex.org/I139351228"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/12","score":1.0,"display_name":"Responsible consumption and production"},{"id":"https://metadata.un.org/sdg/7","score":0.9090999960899353,"display_name":"Affordable and clean energy"},{"id":"https://metadata.un.org/sdg/13","score":0.685699999332428,"display_name":"Climate action"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306084","display_name":"U.S. Department of Energy","ror":"https://ror.org/01bj3aw27"},{"id":"https://openalex.org/F4320338287","display_name":"Oak Ridge National Laboratory","ror":"https://ror.org/01qz5mb56"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2963476189.pdf","grobid_xml":"https://content.openalex.org/works/W2963476189.grobid-xml"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W1563050032","https://openalex.org/W1939556909","https://openalex.org/W1990061397","https://openalex.org/W1995815598","https://openalex.org/W2032327135","https://openalex.org/W2065708815","https://openalex.org/W2091415739","https://openalex.org/W2099047627","https://openalex.org/W2120580364","https://openalex.org/W2124457441","https://openalex.org/W2148044817","https://openalex.org/W2166820820","https://openalex.org/W2179438025","https://openalex.org/W2222718238","https://openalex.org/W2294276789","https://openalex.org/W2412234405","https://openalex.org/W2560534975"],"related_works":["https://openalex.org/W3190778012","https://openalex.org/W3014074251","https://openalex.org/W4404869394","https://openalex.org/W2124826764","https://openalex.org/W4400569000","https://openalex.org/W2093309733","https://openalex.org/W2011704289","https://openalex.org/W4213138979","https://openalex.org/W2339933945","https://openalex.org/W6889698426"],"abstract_inverted_index":{"LanzaTech":[0,181],"and":[1,8,18,22,44,57,75,116,120,144,150,154,158,187,248,275,280],"Oak":[2],"Ridge":[3],"National":[4],"Laboratory":[5],"have":[6,262,281],"developed":[7,66],"scaled":[9],"up":[10],"a":[11,30,42,69,240],"process":[12,40,67,209,229],"for":[13,49,267],"sustainable":[14],"production":[15,47,51,132,204,238,266],"of":[16,102,125,156,161,175,220],"acetone":[17,50,131,142,157,203,222,237,246,265],"downstream":[19],"drop-in":[20],"fuel":[21],"commodity":[23],"products":[24],"directly":[25],"from":[26,205],"biomass":[27,104],"syngas":[28],"via":[29],"novel":[31],"energy":[32],"conserving":[33],"route":[34,72],"in":[35,128,180,198,202,239,258,277],"engineered":[36],"acetogenic":[37],"bacteria.":[38],"This":[39],"offers":[41,68],"safer":[43],"more":[45],"environmentally-friendly":[46],"method":[48],"than":[52],"the":[53,58,221,225,255,283],"current":[54],"phenol-dependent":[55],"method,":[56],"product":[59],"has":[60],"significantly":[61],"lower":[62],"GHG":[63],"emissions.":[64],"The":[65],"cost":[70],"competitive":[71],"to":[73,94,147,230,251],"Acetone":[74],"enables":[76],"biofuels":[77],"at":[78,271],"or":[79],"below":[80],"DOE\u2019s":[81],"$3":[82],"gge":[83],"target.":[84],"In":[85],"addition,":[86],"it":[87],"also":[88],"provides":[89],"an":[90,140],"attractive":[91],"biological":[92],"alternative":[93],"traditional":[95],"sugar-based":[96],"ABE":[97],"fermentation,":[98],"by":[99,123,138,172,218,234],"enabling":[100],"utilization":[101],"non-food":[103],"resources":[105],"as":[106],"fermentation":[107],"feedstocks.":[108],"Challenges":[109],"overcome:":[110],"\u2022":[111,134,167,207,227],"By-products":[112],"formation:":[113],"Byproduct":[114],"2,3-butandiol":[115],"3-hydroxybutyrate":[117],"reduce":[118],"yield":[119,149],"stability.":[121,151],"Addressed":[122,137,171,233],"elimination":[124],"both":[126],"pathways":[127],"our":[129],"chassis":[130],"strain.":[133],"Cost":[135],"competitiveness:":[136],"developing":[139],"integrated":[141],"strain":[143],"eliminating":[145],"by-products":[146],"increase":[148],"Optimized":[152],"co-selectivity":[153],"coproductivity":[155],"ethanol":[159],"instead":[160],"titer,":[162],"based":[163],"on":[164,224],"technoeconomic":[165],"analysis.":[166],"Limited":[168],"enzyme":[169,185,191],"variety:":[170],"genome":[173],"mining":[174],"over":[176,199,268],"300":[177],"industrial":[178],"strains":[179],"collection,":[182],"identifying":[183],"unique":[184,190],"sequences,":[186],"refactoring":[188],"these":[189],"variants":[192],"through":[193,213],"LanzaTech\u2019s":[194],"engineering":[195],"platform.":[196],"Resulted":[197],"10x":[200],"improvement":[201],"gas.":[206],"Continuous":[208],"(stability):":[210],"Identified":[211],"bottleneck":[212],"detailed":[214],"omics":[215],"studies,":[216],"addressed":[217],"integration":[219],"pathway":[223],"chromosome.":[226],"Novel":[228],"scale":[231],"up:":[232],"demonstrating":[235],"stable":[236,264],"80-":[241],"L":[242],"pilot":[243],"reactor,":[244],"with":[245],"productivity":[247],"selectivity":[249,276],"comparable":[250],"those":[252],"observed":[253],"under":[254],"same":[256],"conditions":[257],"2-L":[259,278],"reactors.":[260],"We":[261],"demonstrated":[263],"7":[269],"days":[270],"commercial":[272],"target":[273],"rate":[274],"reactors":[279],"piloted":[282],"process.":[284]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2019-07-30T00:00:00"}