{"id":"https://openalex.org/W2963348613","doi":"https://doi.org/10.3389/fgene.2019.00781","title":"The Challenges of Chromosome Y Analysis and the Implications for Chronic Kidney Disease","display_name":"The Challenges of Chromosome Y Analysis and the Implications for Chronic Kidney Disease","publication_year":2019,"publication_date":"2019-09-04","ids":{"openalex":"https://openalex.org/W2963348613","doi":"https://doi.org/10.3389/fgene.2019.00781","mag":"2963348613","pmid":"https://pubmed.ncbi.nlm.nih.gov/31552093","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6737325"},"language":"en","primary_location":{"id":"doi:10.3389/fgene.2019.00781","doi":"https://doi.org/10.3389/fgene.2019.00781","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fgene.2019.00781","pdf_url":"https://www.frontiersin.org/articles/10.3389/fgene.2019.00781/pdf","source":{"id":"https://openalex.org/S2597340651","display_name":"Frontiers in Genetics","issn_l":"1664-8021","issn":["1664-8021"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Genetics","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fgene.2019.00781/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056830416","display_name":"Kerry Anderson","orcid":"https://orcid.org/0000-0002-3360-3129","observed_orcids":["https://orcid.org/0000-0002-3360-3129"]},"institutions":[{"id":"https://openalex.org/I126231945","display_name":"Queen's University Belfast","ror":"https://ror.org/00hswnk62","country_code":"GB","type":"education","lineage":["https://openalex.org/I126231945"]},{"id":"https://openalex.org/I2802808109","display_name":"Belfast City Hospital","ror":"https://ror.org/02405mj67","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1289110261","https://openalex.org/I2802808109"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Kerry Anderson","raw_affiliation_strings":["Epidemiology and Public Health Research Group, Centre for Public Health, Queen's University of Belfast, c/o Regional Genetics Centre, Belfast City Hospital, Belfast, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epidemiology and Public Health Research Group, Centre for Public Health, Queen's University of Belfast, c/o Regional Genetics Centre, Belfast City Hospital, Belfast, United Kingdom","institution_ids":["https://openalex.org/I126231945","https://openalex.org/I2802808109"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086684710","display_name":"Marisa Ca\u00f1adas\u2010Garre","orcid":"https://orcid.org/0000-0003-1103-5658","observed_orcids":["https://orcid.org/0000-0003-1103-5658"]},"institutions":[{"id":"https://openalex.org/I126231945","display_name":"Queen's University Belfast","ror":"https://ror.org/00hswnk62","country_code":"GB","type":"education","lineage":["https://openalex.org/I126231945"]},{"id":"https://openalex.org/I2802808109","display_name":"Belfast City Hospital","ror":"https://ror.org/02405mj67","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1289110261","https://openalex.org/I2802808109"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Marisa Ca\u00f1adas-Garre","raw_affiliation_strings":["Epidemiology and Public Health Research Group, Centre for Public Health, Queen's University of Belfast, c/o Regional Genetics Centre, Belfast City Hospital, Belfast, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epidemiology and Public Health Research Group, Centre for Public Health, Queen's University of Belfast, c/o Regional Genetics Centre, Belfast City Hospital, Belfast, United Kingdom","institution_ids":["https://openalex.org/I126231945","https://openalex.org/I2802808109"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018665387","display_name":"Robyn Chambers","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126231945","display_name":"Queen's University Belfast","ror":"https://ror.org/00hswnk62","country_code":"GB","type":"education","lineage":["https://openalex.org/I126231945"]},{"id":"https://openalex.org/I2802808109","display_name":"Belfast City Hospital","ror":"https://ror.org/02405mj67","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1289110261","https://openalex.org/I2802808109"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Robyn Chambers","raw_affiliation_strings":["Epidemiology and Public Health Research Group, Centre for Public Health, Queen's University of Belfast, c/o Regional Genetics Centre, Belfast City Hospital, Belfast, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epidemiology and Public Health Research Group, Centre for Public Health, Queen's University of Belfast, c/o Regional Genetics Centre, Belfast City Hospital, Belfast, United Kingdom","institution_ids":["https://openalex.org/I126231945","https://openalex.org/I2802808109"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090093329","display_name":"Alexander Peter Maxwell","orcid":"https://orcid.org/0000-0002-6110-7253","observed_orcids":["https://orcid.org/0000-0002-6110-7253"]},"institutions":[{"id":"https://openalex.org/I126231945","display_name":"Queen's University Belfast","ror":"https://ror.org/00hswnk62","country_code":"GB","type":"education","lineage":["https://openalex.org/I126231945"]},{"id":"https://openalex.org/I2802808109","display_name":"Belfast City Hospital","ror":"https://ror.org/02405mj67","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1289110261","https://openalex.org/I2802808109"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alexander Peter Maxwell","raw_affiliation_strings":["Epidemiology and Public Health Research Group, Centre for Public Health, Queen's University of Belfast, c/o Regional Genetics Centre, Belfast City Hospital, Belfast, United Kingdom","Regional Nephrology Unit, Belfast City Hospital, Belfast, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epidemiology and Public Health Research Group, Centre for Public Health, Queen's University of Belfast, c/o Regional Genetics Centre, Belfast City Hospital, Belfast, United Kingdom","institution_ids":["https://openalex.org/I126231945","https://openalex.org/I2802808109"]},{"raw_affiliation_string":"Regional Nephrology Unit, Belfast City Hospital, Belfast, United Kingdom","institution_ids":["https://openalex.org/I2802808109"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067092840","display_name":"Amy Jayne McKnight","orcid":"https://orcid.org/0000-0002-7482-709X","observed_orcids":["https://orcid.org/0000-0002-7482-709X"]},"institutions":[{"id":"https://openalex.org/I126231945","display_name":"Queen's University Belfast","ror":"https://ror.org/00hswnk62","country_code":"GB","type":"education","lineage":["https://openalex.org/I126231945"]},{"id":"https://openalex.org/I2802808109","display_name":"Belfast City Hospital","ror":"https://ror.org/02405mj67","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1289110261","https://openalex.org/I2802808109"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Amy Jayne McKnight","raw_affiliation_strings":["Epidemiology and Public Health Research Group, Centre for Public Health, Queen's University of Belfast, c/o Regional Genetics Centre, Belfast City Hospital, Belfast, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epidemiology and Public Health Research Group, Centre for Public Health, Queen's University of Belfast, c/o Regional Genetics Centre, Belfast City Hospital, Belfast, United Kingdom","institution_ids":["https://openalex.org/I126231945","https://openalex.org/I2802808109"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5056830416"],"corresponding_institution_ids":["https://openalex.org/I126231945","https://openalex.org/I2802808109"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":0.2452,"has_fulltext":true,"cited_by_count":19,"citation_normalized_percentile":{"value":0.2282839,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"10","issue":null,"first_page":"781","last_page":"781"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11077","display_name":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","score":0.5859000086784363,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11077","display_name":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","score":0.5859000086784363,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.3215000033378601,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.027799999341368675,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/y-chromosome","display_name":"Y chromosome","score":0.953000009059906},{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":0.9909999966621399},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.6240000128746033},{"id":"https://openalex.org/keywords/copy-number-variation","display_name":"copy number variation","score":0.9850000143051147},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9860000014305115},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.6610000133514404},{"id":"https://openalex.org/keywords/genotype-imputation","display_name":"genotype imputation","score":0.593999981880188},{"id":"https://openalex.org/keywords/genotyping-arrays","display_name":"genotyping arrays","score":0.6399999856948853}],"concepts":[{"id":"https://openalex.org/C134925867","wikidata":"https://www.wikidata.org/wiki/Q186380","display_name":"Autosome","level":4,"score":0.7297141551971436},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.668335497379303},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6670979261398315},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.5600003004074097},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.44464224576950073},{"id":"https://openalex.org/C47924181","wikidata":"https://www.wikidata.org/wiki/Q668633","display_name":"Chromosome 3","level":4,"score":0.44259369373321533},{"id":"https://openalex.org/C2780246931","wikidata":"https://www.wikidata.org/wiki/Q202771","display_name":"Y chromosome","level":3,"score":0.44134777784347534},{"id":"https://openalex.org/C54815482","wikidata":"https://www.wikidata.org/wiki/Q753805","display_name":"Chromosome 22","level":4,"score":0.41754376888275146},{"id":"https://openalex.org/C31467283","wikidata":"https://www.wikidata.org/wiki/Q912147","display_name":"Genotyping","level":4,"score":0.4149791896343231},{"id":"https://openalex.org/C68873052","wikidata":"https://www.wikidata.org/wiki/Q349856","display_name":"Genetic variation","level":3,"score":0.41459953784942627},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.2069733738899231},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09664905071258545},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3389/fgene.2019.00781","doi":"https://doi.org/10.3389/fgene.2019.00781","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fgene.2019.00781","pdf_url":"https://www.frontiersin.org/articles/10.3389/fgene.2019.00781/pdf","source":{"id":"https://openalex.org/S2597340651","display_name":"Frontiers in Genetics","issn_l":"1664-8021","issn":["1664-8021"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Genetics","raw_type":"journal-article"},{"id":"pmid:31552093","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31552093","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in genetics","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6737325","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6737325/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Genet","raw_type":"Text"},{"id":"pmh:oai:pure.qub.ac.uk/portal:openaire/4f2fed2a-ae0f-4387-9fc2-55d6b7b335d1","doi":null,"is_oa":true,"landing_page_url":"https://pure.qub.ac.uk/en/publications/4f2fed2a-ae0f-4387-9fc2-55d6b7b335d1","pdf_url":"https://pureadmin.qub.ac.uk/ws/files/182739514/fgene_10_00781.pdf","source":{"id":"https://openalex.org/S4306402319","display_name":"Research Portal (Queen's University Belfast)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I126231945","host_organization_name":"Queen's University Belfast","host_organization_lineage":["https://openalex.org/I126231945"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Anderson, K, Ca\u00f1adas-Garre, M, Chambers, R, Maxwell, A & McKnight, A 2019, 'The challenges of chromosome Y analysis and the implications for chronic kidney disease', Frontiers in Genetics. https://doi.org/10.3389/fgene.2019.00781","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:627406727d174d37be4d56ee7e54a998","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/627406727d174d37be4d56ee7e54a998","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Genetics, Vol 10 (2019)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fgene.2019.00781","doi":"https://doi.org/10.3389/fgene.2019.00781","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fgene.2019.00781","pdf_url":"https://www.frontiersin.org/articles/10.3389/fgene.2019.00781/pdf","source":{"id":"https://openalex.org/S2597340651","display_name":"Frontiers in Genetics","issn_l":"1664-8021","issn":["1664-8021"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Genetics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1356607191","display_name":"Discovery of an integrated risk profile for chronic kidney disease and development of a clinical biomarker panel for personalising medicine","funder_award_id":"15/IA/3152","funder_id":"https://openalex.org/F4320320847","funder_display_name":"Science Foundation Ireland"},{"id":"https://openalex.org/G2394635241","display_name":null,"funder_award_id":"15/IA/3152","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G5659436566","display_name":"The Northern Ireland Genomic Medicine Centre","funder_award_id":"MC_PC_16018","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G6071898252","display_name":null,"funder_award_id":"STL/4760/13","funder_id":"https://openalex.org/F4320320853","funder_display_name":"Public Health Agency"},{"id":"https://openalex.org/G8173526563","display_name":null,"funder_award_id":"15/IA/","funder_id":"https://openalex.org/F4320320847","funder_display_name":"Science Foundation Ireland"},{"id":"https://openalex.org/G8448758501","display_name":"Integrative genomic, epigenetic and functional studies in diabetic kidney disease","funder_award_id":"MC_PC_15025","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G908549105","display_name":null,"funder_award_id":"15/IA/3152","funder_id":"https://openalex.org/F4320316531","funder_display_name":"Department for the Economy"}],"funders":[{"id":"https://openalex.org/F4320316531","display_name":"Department for the Economy","ror":"https://ror.org/0161w0r98"},{"id":"https://openalex.org/F4320320847","display_name":"Science Foundation Ireland","ror":"https://ror.org/0271asj38"},{"id":"https://openalex.org/F4320320853","display_name":"Public Health Agency","ror":"https://ror.org/03ek62e72"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2963348613.pdf","grobid_xml":"https://content.openalex.org/works/W2963348613.grobid-xml"},"referenced_works_count":88,"referenced_works":["https://openalex.org/W1504423993","https://openalex.org/W1724398224","https://openalex.org/W1777203725","https://openalex.org/W1966786568","https://openalex.org/W1967381124","https://openalex.org/W1972141529","https://openalex.org/W1980066896","https://openalex.org/W1980467753","https://openalex.org/W1987093963","https://openalex.org/W1989153414","https://openalex.org/W2014541905","https://openalex.org/W2015531271","https://openalex.org/W2015969984","https://openalex.org/W2022542862","https://openalex.org/W2027996605","https://openalex.org/W2029566195","https://openalex.org/W2029646104","https://openalex.org/W2037668985","https://openalex.org/W2040290929","https://openalex.org/W2045030066","https://openalex.org/W2061971183","https://openalex.org/W2078075583","https://openalex.org/W2085404943","https://openalex.org/W2087036932","https://openalex.org/W2096524158","https://openalex.org/W2100239334","https://openalex.org/W2103492563","https://openalex.org/W2104549677","https://openalex.org/W2110508633","https://openalex.org/W2117651282","https://openalex.org/W2121186261","https://openalex.org/W2128016314","https://openalex.org/W2128298945","https://openalex.org/W2135959382","https://openalex.org/W2137094295","https://openalex.org/W2141995338","https://openalex.org/W2148161327","https://openalex.org/W2149791927","https://openalex.org/W2149892026","https://openalex.org/W2151165394","https://openalex.org/W2155058663","https://openalex.org/W2156851441","https://openalex.org/W2162600042","https://openalex.org/W2163255949","https://openalex.org/W2165070736","https://openalex.org/W2169580995","https://openalex.org/W2172799796","https://openalex.org/W2211493026","https://openalex.org/W2222141405","https://openalex.org/W2262485132","https://openalex.org/W2279744393","https://openalex.org/W2289678372","https://openalex.org/W2295638588","https://openalex.org/W2324325959","https://openalex.org/W2325975545","https://openalex.org/W2331272359","https://openalex.org/W2405684830","https://openalex.org/W2411709723","https://openalex.org/W2461811699","https://openalex.org/W2465528287","https://openalex.org/W2470481127","https://openalex.org/W2487180529","https://openalex.org/W2511420195","https://openalex.org/W2511515754","https://openalex.org/W2521487197","https://openalex.org/W2559028527","https://openalex.org/W2566323743","https://openalex.org/W2582179907","https://openalex.org/W2605722421","https://openalex.org/W2609071159","https://openalex.org/W2613686629","https://openalex.org/W2724364141","https://openalex.org/W2783075063","https://openalex.org/W2796531147","https://openalex.org/W2883622734","https://openalex.org/W2883690959","https://openalex.org/W2889469195","https://openalex.org/W2891631301","https://openalex.org/W2894889219","https://openalex.org/W2895486342","https://openalex.org/W2898273140","https://openalex.org/W2901347025","https://openalex.org/W2901438556","https://openalex.org/W2906428833","https://openalex.org/W2947001480","https://openalex.org/W2951470692","https://openalex.org/W2962240230","https://openalex.org/W4250359879"],"related_works":["https://openalex.org/W2950211661","https://openalex.org/W2937109682","https://openalex.org/W2887140007","https://openalex.org/W6967597938","https://openalex.org/W2618309686","https://openalex.org/W4398232266","https://openalex.org/W2947001480","https://openalex.org/W2015969984","https://openalex.org/W2026904057","https://openalex.org/W3049359784"],"abstract_inverted_index":{"The":[0,23,113],"role":[1],"of":[2,27,102,128,168,194,205,208,215,219],"chromosome":[3,13,33,61,106,116,146,158,187,209,224,228],"Y":[4,14,34,62,77,107,117,159,188,210,229],"in":[5,21,73,105,111,136,180,191,197],"chronic":[6],"kidney":[7],"disease":[8],"(CKD)":[9],"remains":[10],"unknown,":[11],"as":[12],"is":[15,39,152,189,232],"typically":[16],"excluded":[17,157],"from":[18],"genetic":[19,35,63,103,220,230],"analysis":[20,214],"CKD.":[22,112,195,235],"complex,":[24],"sex-specific":[25],"presentation":[26],"CKD":[28,74,90,120,137],"could":[29,200],"be":[30,54,201],"influenced":[31],"by":[32],"variation,":[36,132],"but":[37],"there":[38],"limited":[40,141],"published":[41],"research":[42],"available":[43],"to":[44,53,65,89,142,225],"confirm":[45],"or":[46,145,160,177],"reject":[47],"this":[48],"hypothesis.":[49],"Although":[50],"traditionally":[51],"thought":[52],"associated":[55,81,233],"with":[56,82,93,182,234],"male-specific":[57],"disease,":[58,84],"evidence":[59],"linking":[60],"variation":[64,78,104,221,231],"common":[66],"complex":[67],"disorders":[68],"highlights":[69],"a":[70,85,94],"potential":[71],"gap":[72],"research.":[75],"Chromosome":[76],"has":[79,121],"been":[80,109,123,139],"cardiovascular":[83],"condition":[86],"closely":[87],"linked":[88],"and":[91,119,133,173],"one":[92],"very":[95],"similar":[96],"sexual":[97],"dimorphism.":[98],"Relatively":[99],"few":[100],"sources":[101],"have":[108,138],"examined":[110],"association":[114],"between":[115],"aneuploidy":[118],"never":[122],"explored":[124],"comprehensively,":[125],"while":[126],"analyses":[127,156,179],"microdeletions,":[129],"copy":[130],"number":[131],"single-nucleotide":[134],"polymorphisms":[135],"largely":[140],"the":[143,155,192,223],"autosomes":[144],"X.":[147],"In":[148],"many":[149,216],"studies,":[150],"it":[151],"unclear":[153],"whether":[154],"simply":[161],"did":[162],"not":[163],"report":[164],"negative":[165],"results.":[166],"Lack":[167],"imputation,":[169],"poor":[170],"cross-study":[171],"comparability,":[172],"requirement":[174],"for":[175],"separate":[176],"additional":[178],"comparison":[181],"autosomal":[183],"chromosomes":[184],"means":[185],"that":[186,211],"under-investigated":[190],"context":[193],"Limitations":[196],"genotyping":[198],"arrays":[199],"overcome":[202],"through":[203],"use":[204],"whole-chromosome":[206],"sequencing":[207],"may":[212],"allow":[213],"different":[217],"types":[218],"across":[222],"determine":[226],"if":[227]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2019-07-30T00:00:00"}
