{"id":"https://openalex.org/W2963035076","doi":"https://doi.org/10.1097/mpg.0000000000002450","title":"Biliary Atresia as a Disease Starting In Utero","display_name":"Biliary Atresia as a Disease Starting In Utero","publication_year":2019,"publication_date":"2019-07-21","ids":{"openalex":"https://openalex.org/W2963035076","doi":"https://doi.org/10.1097/mpg.0000000000002450","mag":"2963035076","pmid":"https://pubmed.ncbi.nlm.nih.gov/31335837","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6942669"},"language":"en","primary_location":{"id":"doi:10.1097/mpg.0000000000002450","doi":"https://doi.org/10.1097/mpg.0000000000002450","is_oa":false,"landing_page_url":"https://doi.org/10.1097/mpg.0000000000002450","pdf_url":null,"source":{"id":"https://openalex.org/S197964821","display_name":"Journal of Pediatric Gastroenterology and Nutrition","issn_l":"0277-2116","issn":["0277-2116","1536-4801"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pediatric Gastroenterology and Nutrition","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007382188","display_name":"Krupa R. Mysore","orcid":"https://orcid.org/0000-0001-9890-5518","observed_orcids":["https://orcid.org/0000-0001-9890-5518"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I4210147586","display_name":"Texas Children's Hospital","ror":"https://ror.org/05cz92x43","country_code":"US","type":"funder","lineage":["https://openalex.org/I4210147586"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Krupa R. Mysore","raw_affiliation_strings":["Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Baylor College of Medicine and Texas Children's Hospital, Houston, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Baylor College of Medicine and Texas Children's Hospital, Houston, TX","institution_ids":["https://openalex.org/I181547552","https://openalex.org/I4210147586"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020707089","display_name":"Benjamin L. Shneider","orcid":"https://orcid.org/0000-0002-7208-0949","observed_orcids":["https://orcid.org/0000-0002-7208-0949"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I4210147586","display_name":"Texas Children's Hospital","ror":"https://ror.org/05cz92x43","country_code":"US","type":"funder","lineage":["https://openalex.org/I4210147586"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Benjamin L. Shneider","raw_affiliation_strings":["Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Baylor College of Medicine and Texas Children's Hospital, Houston, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Baylor College of Medicine and Texas Children's Hospital, Houston, TX","institution_ids":["https://openalex.org/I181547552","https://openalex.org/I4210147586"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072849093","display_name":"Sanjiv Harpavat","orcid":"https://orcid.org/0000-0002-9964-2294","observed_orcids":["https://orcid.org/0000-0002-9964-2294"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I4210147586","display_name":"Texas Children's Hospital","ror":"https://ror.org/05cz92x43","country_code":"US","type":"funder","lineage":["https://openalex.org/I4210147586"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sanjiv Harpavat","raw_affiliation_strings":["Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Baylor College of Medicine and Texas Children's Hospital, Houston, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Baylor College of Medicine and Texas Children's Hospital, Houston, TX","institution_ids":["https://openalex.org/I181547552","https://openalex.org/I4210147586"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5072849093"],"corresponding_institution_ids":["https://openalex.org/I181547552","https://openalex.org/I4210147586"],"apc_list":{"value":3780,"currency":"USD","value_usd":3780},"apc_paid":null,"fwci":1.5993,"has_fulltext":false,"cited_by_count":68,"citation_normalized_percentile":{"value":0.83712066,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"69","issue":"4","first_page":"396","last_page":"403"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12460","display_name":"Pediatric Hepatobiliary Diseases and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12460","display_name":"Pediatric Hepatobiliary Diseases and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10999","display_name":"Organ Transplantation Techniques and Outcomes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11834","display_name":"Liver Diseases and Immunity","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biliary-atresia","display_name":"biliary atresia","score":1.0},{"id":"https://openalex.org/keywords/prenatal-onset","display_name":"prenatal onset","score":0.6620000004768372},{"id":"https://openalex.org/keywords/kasai-procedure","display_name":"Kasai portoenterostomy","score":0.9810000061988831},{"id":"https://openalex.org/keywords/pediatric-liver-transplantation","display_name":"pediatric liver transplantation","score":0.972000002861023},{"id":"https://openalex.org/keywords/etiology","display_name":"etiology","score":0.6549999713897705},{"id":"https://openalex.org/keywords/neonatal-biliary-obstruction","display_name":"neonatal biliary obstruction","score":0.4909999966621399},{"id":"https://openalex.org/keywords/prenatal-imaging","display_name":"fetal imaging","score":0.3619999885559082}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9484002590179443},{"id":"https://openalex.org/C201614185","wikidata":"https://www.wikidata.org/wiki/Q396833","display_name":"In utero","level":4,"score":0.8923065662384033},{"id":"https://openalex.org/C2779243279","wikidata":"https://www.wikidata.org/wiki/Q659033","display_name":"Biliary atresia","level":4,"score":0.7881832122802734},{"id":"https://openalex.org/C2910372796","wikidata":"https://www.wikidata.org/wiki/Q851111","display_name":"Bile Duct Diseases","level":3,"score":0.5511918067932129},{"id":"https://openalex.org/C2781149206","wikidata":"https://www.wikidata.org/wiki/Q757722","display_name":"Atresia","level":2,"score":0.4494136571884155},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.41044241189956665},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.3066527545452118},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2854468524456024},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.19719374179840088},{"id":"https://openalex.org/C2779609443","wikidata":"https://www.wikidata.org/wiki/Q1368191","display_name":"Liver transplantation","level":3,"score":0.08964601159095764},{"id":"https://openalex.org/C2779777945","wikidata":"https://www.wikidata.org/wiki/Q851111","display_name":"Bile duct","level":2,"score":0.06085860729217529},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.05191478133201599},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001656","descriptor_name":"Biliary Atresia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011296","descriptor_name":"Prenatal Diagnosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015997","descriptor_name":"Neonatal Screening","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1097/mpg.0000000000002450","doi":"https://doi.org/10.1097/mpg.0000000000002450","is_oa":false,"landing_page_url":"https://doi.org/10.1097/mpg.0000000000002450","pdf_url":null,"source":{"id":"https://openalex.org/S197964821","display_name":"Journal of Pediatric Gastroenterology and Nutrition","issn_l":"0277-2116","issn":["0277-2116","1536-4801"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pediatric Gastroenterology and Nutrition","raw_type":"journal-article"},{"id":"pmid:31335837","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31335837","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of pediatric gastroenterology and nutrition","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1973259810","display_name":"Assessment of a Novel Newborn Screening Tool for Biliary Atresia","funder_award_id":"K23DK109207","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":63,"referenced_works":["https://openalex.org/W125216147","https://openalex.org/W611123340","https://openalex.org/W1582101032","https://openalex.org/W1635080883","https://openalex.org/W1646376540","https://openalex.org/W1943002894","https://openalex.org/W1975612283","https://openalex.org/W1975779479","https://openalex.org/W1978306498","https://openalex.org/W1993348623","https://openalex.org/W2000669554","https://openalex.org/W2021636056","https://openalex.org/W2023807575","https://openalex.org/W2024239709","https://openalex.org/W2026609029","https://openalex.org/W2027802936","https://openalex.org/W2031300327","https://openalex.org/W2038467243","https://openalex.org/W2038802814","https://openalex.org/W2039442002","https://openalex.org/W2052969752","https://openalex.org/W2056466288","https://openalex.org/W2063374568","https://openalex.org/W2068894050","https://openalex.org/W2069775930","https://openalex.org/W2071618738","https://openalex.org/W2077085751","https://openalex.org/W2077129494","https://openalex.org/W2082300278","https://openalex.org/W2086721472","https://openalex.org/W2096755247","https://openalex.org/W2107051416","https://openalex.org/W2111295992","https://openalex.org/W2148713740","https://openalex.org/W2152585013","https://openalex.org/W2161651267","https://openalex.org/W2255081014","https://openalex.org/W2321022211","https://openalex.org/W2326592643","https://openalex.org/W2335756301","https://openalex.org/W2336195635","https://openalex.org/W2340874693","https://openalex.org/W2480517066","https://openalex.org/W2492650050","https://openalex.org/W2532021397","https://openalex.org/W2614461394","https://openalex.org/W2617725103","https://openalex.org/W2737027390","https://openalex.org/W2766942882","https://openalex.org/W2770414417","https://openalex.org/W2782408025","https://openalex.org/W2789372206","https://openalex.org/W2793826081","https://openalex.org/W2794632001","https://openalex.org/W2805578266","https://openalex.org/W2889286923","https://openalex.org/W2912706849","https://openalex.org/W2912777063","https://openalex.org/W2914571086","https://openalex.org/W2917608643","https://openalex.org/W2921727813","https://openalex.org/W2922247271","https://openalex.org/W4206682781"],"related_works":["https://openalex.org/W2329281687","https://openalex.org/W1998979877","https://openalex.org/W2789239816","https://openalex.org/W1980831586","https://openalex.org/W2102370508","https://openalex.org/W2055678738","https://openalex.org/W2977565759","https://openalex.org/W4313576103","https://openalex.org/W1980410073","https://openalex.org/W2004820711"],"abstract_inverted_index":{"Biliary":[0],"atresia":[1],"(BA)":[2],"is":[3],"the":[4,20],"most":[5,52],"common":[6],"reason":[7],"for":[8],"pediatric":[9],"liver":[10],"transplant.":[11],"BA's":[12,79],"varied":[13],"presentation,":[14],"natural":[15],"history,":[16],"and":[17,46,74],"treatment":[18],"with":[19],"Kasai":[21],"portoenterostomy":[22],"have":[23],"been":[24,36],"well":[25],"described;":[26],"however,":[27],"when":[28],"BA":[29,58],"starts":[30],"relative":[31],"to":[32],"birth":[33],"has":[34,66],"not":[35,54],"clearly":[37],"defined.":[38],"In":[39],"this":[40],"review,":[41],"we":[42],"discuss":[43],"laboratory,":[44],"imaging,":[45],"clinical":[47],"data":[48],"which":[49],"suggest":[50],"that":[51],"if":[53],"all":[55],"forms":[56],"of":[57,70],"may":[59],"start":[60],"before":[61],"birth.":[62],"This":[63],"early":[64],"onset":[65],"implications":[67],"in":[68],"terms":[69],"delivering":[71],"treatments":[72],"earlier":[73],"identifying":[75],"possible":[76],"factors":[77],"underlying":[78],"etiology.":[80]},"counts_by_year":[{"year":2026,"cited_by_count":11},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":13},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-07-30T00:00:00"}
