{"id":"https://openalex.org/W2962716786","doi":"https://doi.org/10.1101/713206","title":"Identification of porcine RUNX1 as an LPS-dependent gene expression regulator in PBMCs by Super deepSAGE sequencing of multiple tissues","display_name":"Identification of porcine RUNX1 as an LPS-dependent gene expression regulator in PBMCs by Super deepSAGE sequencing of multiple tissues","publication_year":2019,"publication_date":"2019-07-24","ids":{"openalex":"https://openalex.org/W2962716786","doi":"https://doi.org/10.1101/713206","mag":"2962716786"},"language":"en","primary_location":{"id":"doi:10.1101/713206","doi":"https://doi.org/10.1101/713206","is_oa":true,"landing_page_url":"https://doi.org/10.1101/713206","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2019/07/24/713206.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nd","license_id":"https://openalex.org/licenses/cc-by-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.biorxiv.org/content/biorxiv/early/2019/07/24/713206.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017309162","display_name":"Tinghua Huang","orcid":"https://orcid.org/0000-0003-0387-9834","observed_orcids":["https://orcid.org/0000-0003-0387-9834"]},"institutions":[{"id":"https://openalex.org/I177739611","display_name":"Yangtze University","ror":"https://ror.org/05bhmhz54","country_code":"CN","type":"education","lineage":["https://openalex.org/I177739611"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tinghua Huang","raw_affiliation_strings":["College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China","institution_ids":["https://openalex.org/I177739611"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101478395","display_name":"Min Yang","orcid":"https://orcid.org/0000-0003-2980-294X","observed_orcids":["https://orcid.org/0000-0003-2980-294X","https://orcid.org/0000-0002-6811-2709"]},"institutions":[{"id":"https://openalex.org/I177739611","display_name":"Yangtze University","ror":"https://ror.org/05bhmhz54","country_code":"CN","type":"education","lineage":["https://openalex.org/I177739611"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Min Yang","raw_affiliation_strings":["College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China","institution_ids":["https://openalex.org/I177739611"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020548959","display_name":"Kaihui Dong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177739611","display_name":"Yangtze University","ror":"https://ror.org/05bhmhz54","country_code":"CN","type":"education","lineage":["https://openalex.org/I177739611"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kaihui Dong","raw_affiliation_strings":["College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China","institution_ids":["https://openalex.org/I177739611"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Mingjiang Xu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177739611","display_name":"Yangtze University","ror":"https://ror.org/05bhmhz54","country_code":"CN","type":"education","lineage":["https://openalex.org/I177739611"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mingjiang Xu","raw_affiliation_strings":["College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China","institution_ids":["https://openalex.org/I177739611"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100766359","display_name":"Jinhui Liu","orcid":"https://orcid.org/0000-0001-8032-5099","observed_orcids":["https://orcid.org/0000-0001-8032-5099","https://orcid.org/0009-0000-7324-1479","https://orcid.org/0009-0003-1810-4633"]},"institutions":[{"id":"https://openalex.org/I177739611","display_name":"Yangtze University","ror":"https://ror.org/05bhmhz54","country_code":"CN","type":"education","lineage":["https://openalex.org/I177739611"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jinhui Liu","raw_affiliation_strings":["College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China","institution_ids":["https://openalex.org/I177739611"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100456807","display_name":"Zhi Chen","orcid":"https://orcid.org/0000-0002-1466-3767","observed_orcids":["https://orcid.org/0000-0002-1466-3767"]},"institutions":[{"id":"https://openalex.org/I177739611","display_name":"Yangtze University","ror":"https://ror.org/05bhmhz54","country_code":"CN","type":"education","lineage":["https://openalex.org/I177739611"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhi Chen","raw_affiliation_strings":["College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China","institution_ids":["https://openalex.org/I177739611"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038868843","display_name":"Shijia Zhu","orcid":"https://orcid.org/0000-0002-2368-2361","observed_orcids":["https://orcid.org/0000-0002-2368-2361"]},"institutions":[{"id":"https://openalex.org/I177739611","display_name":"Yangtze University","ror":"https://ror.org/05bhmhz54","country_code":"CN","type":"education","lineage":["https://openalex.org/I177739611"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shijia Zhu","raw_affiliation_strings":["College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China","institution_ids":["https://openalex.org/I177739611"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103529797","display_name":"Wang Chen","orcid":"https://orcid.org/0009-0007-8281-9456","observed_orcids":["https://orcid.org/0009-0007-8281-9456"]},"institutions":[{"id":"https://openalex.org/I177739611","display_name":"Yangtze University","ror":"https://ror.org/05bhmhz54","country_code":"CN","type":"education","lineage":["https://openalex.org/I177739611"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wang Chen","raw_affiliation_strings":["College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China","institution_ids":["https://openalex.org/I177739611"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108324877","display_name":"Jun Yin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177739611","display_name":"Yangtze University","ror":"https://ror.org/05bhmhz54","country_code":"CN","type":"education","lineage":["https://openalex.org/I177739611"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Yin","raw_affiliation_strings":["College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China","institution_ids":["https://openalex.org/I177739611"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Kai Jin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177739611","display_name":"Yangtze University","ror":"https://ror.org/05bhmhz54","country_code":"CN","type":"education","lineage":["https://openalex.org/I177739611"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kai Jin","raw_affiliation_strings":["College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China","institution_ids":["https://openalex.org/I177739611"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101522187","display_name":"Yu Deng","orcid":"https://orcid.org/0000-0001-6065-512X","observed_orcids":["https://orcid.org/0000-0001-6065-512X"]},"institutions":[{"id":"https://openalex.org/I177739611","display_name":"Yangtze University","ror":"https://ror.org/05bhmhz54","country_code":"CN","type":"education","lineage":["https://openalex.org/I177739611"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yu Deng","raw_affiliation_strings":["College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China","institution_ids":["https://openalex.org/I177739611"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088169503","display_name":"Zhou Guan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177739611","display_name":"Yangtze University","ror":"https://ror.org/05bhmhz54","country_code":"CN","type":"education","lineage":["https://openalex.org/I177739611"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhou Guan","raw_affiliation_strings":["College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China","institution_ids":["https://openalex.org/I177739611"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039663083","display_name":"Xiali Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177739611","display_name":"Yangtze University","ror":"https://ror.org/05bhmhz54","country_code":"CN","type":"education","lineage":["https://openalex.org/I177739611"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiali Huang","raw_affiliation_strings":["College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China","institution_ids":["https://openalex.org/I177739611"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074885042","display_name":"Jun Yang","orcid":"https://orcid.org/0000-0002-1008-0388","observed_orcids":["https://orcid.org/0000-0002-1008-0388"]},"institutions":[{"id":"https://openalex.org/I177739611","display_name":"Yangtze University","ror":"https://ror.org/05bhmhz54","country_code":"CN","type":"education","lineage":["https://openalex.org/I177739611"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Yang","raw_affiliation_strings":["College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China","institution_ids":["https://openalex.org/I177739611"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112672797","display_name":"Rongxun Han","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177739611","display_name":"Yangtze University","ror":"https://ror.org/05bhmhz54","country_code":"CN","type":"education","lineage":["https://openalex.org/I177739611"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rongxun Han","raw_affiliation_strings":["College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China","institution_ids":["https://openalex.org/I177739611"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019943934","display_name":"Min Yao","orcid":"https://orcid.org/0000-0002-9867-7372","observed_orcids":["https://orcid.org/0000-0002-9867-7372"]},"institutions":[{"id":"https://openalex.org/I177739611","display_name":"Yangtze University","ror":"https://ror.org/05bhmhz54","country_code":"CN","type":"education","lineage":["https://openalex.org/I177739611"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Min Yao","raw_affiliation_strings":["College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Animal Science, Yangtze University, Jingzhou, Hubei 434025, China","institution_ids":["https://openalex.org/I177739611"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5019943934"],"corresponding_institution_ids":["https://openalex.org/I177739611"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.423799991607666,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.423799991607666,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.211899995803833,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.11180000007152557,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/runx1","display_name":"RUNX1","score":0.8740000128746033},{"id":"https://openalex.org/keywords/transcription-factors","display_name":"transcription factors","score":0.6010000109672546},{"id":"https://openalex.org/keywords/peripheral-blood-mononuclear-cells","display_name":"peripheral blood mononuclear cells","score":0.9459999799728394},{"id":"https://openalex.org/keywords/tlr2","display_name":"TLR2","score":0.9120000004768372},{"id":"https://openalex.org/keywords/lck","display_name":"Lck","score":0.7179999947547913},{"id":"https://openalex.org/keywords/vav1","display_name":"Vav1","score":0.9950000047683716},{"id":"https://openalex.org/keywords/bacterial-infection","display_name":"bacterial infection","score":0.7250000238418579},{"id":"https://openalex.org/keywords/immune-disorders","display_name":"immune disorders","score":0.5910000205039978},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"gene expression profiling","score":0.43700000643730164}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7802633047103882},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6908300518989563},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.5757774114608765},{"id":"https://openalex.org/C2778193527","wikidata":"https://www.wikidata.org/wiki/Q15320451","display_name":"RUNX1","level":4,"score":0.5754836201667786},{"id":"https://openalex.org/C18431079","wikidata":"https://www.wikidata.org/wiki/Q1502169","display_name":"Gene expression profiling","level":4,"score":0.5743331909179688},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.5302668809890747},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.4958373010158539},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.46439650654792786},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.44484972953796387}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1101/713206","doi":"https://doi.org/10.1101/713206","is_oa":true,"landing_page_url":"https://doi.org/10.1101/713206","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2019/07/24/713206.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nd","license_id":"https://openalex.org/licenses/cc-by-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"doi:10.21203/rs.2.14057/v1","doi":"https://doi.org/10.21203/rs.2.14057/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.2.14057/v1","pdf_url":"https://www.researchsquare.com/article/rs-4756/v1.pdf?c=1631841473000","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1101/713206","doi":"https://doi.org/10.1101/713206","is_oa":true,"landing_page_url":"https://doi.org/10.1101/713206","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2019/07/24/713206.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nd","license_id":"https://openalex.org/licenses/cc-by-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G8688248800","display_name":null,"funder_award_id":"31402055","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320324773","display_name":"Yangtze University","ror":"https://ror.org/05bhmhz54"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2962716786.pdf","grobid_xml":"https://content.openalex.org/works/W2962716786.grobid-xml"},"referenced_works_count":51,"referenced_works":["https://openalex.org/W1604994656","https://openalex.org/W1611682757","https://openalex.org/W1829757075","https://openalex.org/W1988471126","https://openalex.org/W1989316972","https://openalex.org/W1996673956","https://openalex.org/W2001358928","https://openalex.org/W2002982210","https://openalex.org/W2004773897","https://openalex.org/W2010888033","https://openalex.org/W2018643387","https://openalex.org/W2020541351","https://openalex.org/W2022756254","https://openalex.org/W2025002368","https://openalex.org/W2032065412","https://openalex.org/W2035892324","https://openalex.org/W2036005213","https://openalex.org/W2038460592","https://openalex.org/W2061160523","https://openalex.org/W2073849744","https://openalex.org/W2082112045","https://openalex.org/W2083509286","https://openalex.org/W2084051071","https://openalex.org/W2086802511","https://openalex.org/W2115809399","https://openalex.org/W2122889787","https://openalex.org/W2123490534","https://openalex.org/W2123724865","https://openalex.org/W2123794543","https://openalex.org/W2130439971","https://openalex.org/W2131080367","https://openalex.org/W2143368483","https://openalex.org/W2143811987","https://openalex.org/W2146512944","https://openalex.org/W2154681634","https://openalex.org/W2164683872","https://openalex.org/W2165787335","https://openalex.org/W2172052253","https://openalex.org/W2406250479","https://openalex.org/W2412418425","https://openalex.org/W2470149448","https://openalex.org/W2542719952","https://openalex.org/W2611715557","https://openalex.org/W2770178180","https://openalex.org/W2784199543","https://openalex.org/W2802396666","https://openalex.org/W2904624722","https://openalex.org/W2921042711","https://openalex.org/W2945980687","https://openalex.org/W4213387068","https://openalex.org/W4230397979"],"related_works":["https://openalex.org/W3010720223","https://openalex.org/W2988993448","https://openalex.org/W6901872967","https://openalex.org/W4400999844","https://openalex.org/W4402788391","https://openalex.org/W2618994950","https://openalex.org/W2004540012","https://openalex.org/W4390700155","https://openalex.org/W6977519000","https://openalex.org/W1999447183"],"abstract_inverted_index":{"Abstract":[0],"Background:":[1],"Gene":[2],"expression":[3,29,119,205,215],"regulators":[4,131],"identified":[5,129,218],"in":[6,18,158],"transcriptome":[7],"profiling":[8],"experiment":[9],"may":[10],"be":[11],"selected":[12,165],"as":[13,103,105],"targets":[14,236],"for":[15,35,57,170,210,237],"genetic":[16],"manipulations":[17],"farm":[19],"animals.":[20],"Results:":[21],"In":[22],"this":[23,140],"study,":[24],"we":[25,134],"developed":[26],"a":[27,136,233],"gene":[28,214],"profile":[30],"of":[31,74,99,108,115,139,173,242],"76,000+":[32],"unique":[33],"transcripts":[34],"224":[36],"porcine":[37,213],"samples":[38,63],"from":[39,44,64],"28":[40],"normal":[41],"tissues":[42,67],"collected":[43],"32":[45],"animals":[46],"using":[47],"Super":[48,76,199],"deepSAGE":[49,77,200],"technology.":[50],"Excellent":[51],"sequencing":[52],"depth":[53],"has":[54],"been":[55],"achieved":[56],"each":[58],"multiplexed":[59],"library,":[60],"and":[61,132,144,183,192,202,226,240,245],"replicated":[62],"the":[65,71,75,97,100,106,171,190,198,212,224,238],"same":[66],"cluster":[68],"together,":[69],"demonstrating":[70],"high":[72],"quality":[73],"data.":[78],"Comparison":[79],"with":[80],"previous":[81],"research":[82,146],"indicated":[83],"that":[84],"our":[85],"results":[86],"not":[87],"only":[88],"have":[89,94],"excellent":[90],"reproducibility":[91],"but":[92],"also":[93],"greatly":[95],"extended":[96],"coverage":[98],"sample":[101],"types":[102],"well":[104],"number":[107],"genes.":[109],"Clustering":[110],"analysis":[111,128],"discovered":[112],"ten":[113],"groups":[114],"genes":[116,166,221],"showing":[117],"distinct":[118],"patterns":[120],"among":[121],"those":[122],"samples.":[123],"Binding":[124],"motif":[125],"over":[126],"representative":[127],"41":[130],"finally,":[133],"demonstrate":[135],"potential":[137,234],"application":[138],"dataset":[141],"to":[142,189,223],"infectious":[143],"immune":[145,247],"by":[147],"identifying":[148],"an":[149],"LPS-dependent":[150],"transcription":[151,154,172],"factor,":[152],"runt-related":[153],"factor":[155],"1":[156],"(RUNX1),":[157],"peripheral":[159],"blood":[160],"mononuclear":[161],"cells":[162],"(PBMCs).":[163],"The":[164,217],"are":[167,207],"specifically":[168],"responsible":[169],"toll-like":[174],"receptor":[175],"2":[176],"(TLR2),":[177],"lymphocyte-specific":[178],"protein":[179],"tyrosine":[180],"kinase":[181],"(LCK),":[182],"vav1":[184],"oncogene":[185],"(VAV1),":[186],"which":[187],"belong":[188,222],"T":[191,225],"B":[193,227],"cell":[194,228],"signaling":[195,229],"pathways.":[196],"Conclusions:":[197],"technology":[201],"tissue":[203],"specific":[204],"profiles":[206],"valuable":[208],"resources":[209],"investigating":[211],"regulations.":[216],"RUNX1":[219],"target":[220],"pathways,":[230],"making":[231],"it":[232],"novel":[235],"diagnostic":[239],"therapy":[241],"bacterial":[243],"infections":[244],"other":[246],"disorders.":[248]},"counts_by_year":[],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2019-07-30T00:00:00"}