{"id":"https://openalex.org/W2960799015","doi":"https://doi.org/10.3233/cbm-190168","title":"Bivalent property of intra-platelet VWF in liver regeneration and HCC recurrence: A prospective multicenter study","display_name":"Bivalent property of intra-platelet VWF in liver regeneration and HCC recurrence: A prospective multicenter study","publication_year":2019,"publication_date":"2019-07-16","ids":{"openalex":"https://openalex.org/W2960799015","doi":"https://doi.org/10.3233/cbm-190168","mag":"2960799015","pmid":"https://pubmed.ncbi.nlm.nih.gov/31322547","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12826445"},"language":"en","primary_location":{"id":"doi:10.3233/cbm-190168","doi":"https://doi.org/10.3233/cbm-190168","is_oa":false,"landing_page_url":"https://doi.org/10.3233/cbm-190168","pdf_url":null,"source":{"id":"https://openalex.org/S61994691","display_name":"Cancer Biomarkers","issn_l":"1574-0153","issn":["1574-0153","1875-8592"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Biomarkers","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12826445/pdf/cbm-26-cbm190168.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020154361","display_name":"Bibek Aryal","orcid":"https://orcid.org/0000-0003-0257-7439","observed_orcids":["https://orcid.org/0000-0003-0257-7439"]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Bibek Aryal","raw_affiliation_strings":["Cardiovascular and Gastroenterological Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8520, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular and Gastroenterological Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8520, Japan","institution_ids":["https://openalex.org/I107139324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014777914","display_name":"Munekazu Yamakuchi","orcid":"https://orcid.org/0000-0003-2181-7194","observed_orcids":["https://orcid.org/0000-0003-2181-7194"]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Munekazu Yamakuchi","raw_affiliation_strings":["Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8520, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8520, Japan","institution_ids":["https://openalex.org/I107139324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001206797","display_name":"Toshiaki Shimizu","orcid":"https://orcid.org/0000-0003-0364-0022","observed_orcids":["https://orcid.org/0000-0003-0364-0022"]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshiaki Shimizu","raw_affiliation_strings":["Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8520, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8520, Japan","institution_ids":["https://openalex.org/I107139324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087340508","display_name":"Jun Kadono","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jun Kadono","raw_affiliation_strings":["Department of Surgery, Kirishima Medical Center, Kirishima 899-5112, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Kirishima Medical Center, Kirishima 899-5112, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113770846","display_name":"Akira Furoi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Akira Furoi","raw_affiliation_strings":["Department of Surgery, Kirishima Medical Center, Kirishima 899-5112, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Kirishima Medical Center, Kirishima 899-5112, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010592352","display_name":"Kentaro Gejima","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kentaro Gejima","raw_affiliation_strings":["Cardiovascular and Gastroenterological Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8520, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular and Gastroenterological Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8520, Japan","institution_ids":["https://openalex.org/I107139324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022657172","display_name":"Kazunori Takenouchi","orcid":"https://orcid.org/0000-0003-1946-457X","observed_orcids":["https://orcid.org/0000-0003-1946-457X"]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazunori Takenouchi","raw_affiliation_strings":["Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8520, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8520, Japan","institution_ids":["https://openalex.org/I107139324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089989704","display_name":"Teruo Komokata","orcid":"https://orcid.org/0000-0002-1026-0194","observed_orcids":["https://orcid.org/0000-0002-1026-0194"]},"institutions":[{"id":"https://openalex.org/I4210137409","display_name":"National Hospital Organization","ror":"https://ror.org/03ntccx93","country_code":"JP","type":"government","lineage":["https://openalex.org/I4210137409"]},{"id":"https://openalex.org/I4210142225","display_name":"Kagoshima Medical Center","ror":"https://ror.org/03nd0nz77","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210137409","https://openalex.org/I4210142225"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Teruo Komokata","raw_affiliation_strings":["Department of Surgery, Kagoshima Medical Center, National Hospital Organization, Kagoshima 892-0853, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Kagoshima Medical Center, National Hospital Organization, Kagoshima 892-0853, Japan","institution_ids":["https://openalex.org/I4210137409","https://openalex.org/I4210142225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045140590","display_name":"Teruto Hashiguchi","orcid":"https://orcid.org/0000-0003-4820-8268","observed_orcids":["https://orcid.org/0000-0003-4820-8268"]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Teruto Hashiguchi","raw_affiliation_strings":["Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8520, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8520, Japan","institution_ids":["https://openalex.org/I107139324"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046686629","display_name":"Yutaka Imoto","orcid":"https://orcid.org/0000-0002-6094-456X","observed_orcids":["https://orcid.org/0000-0002-6094-456X"]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yutaka Imoto","raw_affiliation_strings":["Cardiovascular and Gastroenterological Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8520, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular and Gastroenterological Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8520, Japan","institution_ids":["https://openalex.org/I107139324"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5014777914","https://openalex.org/A5020154361","https://openalex.org/A5045140590"],"corresponding_institution_ids":["https://openalex.org/I107139324"],"apc_list":null,"apc_paid":null,"fwci":0.7104,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.69751635,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"26","issue":"1","first_page":"51","last_page":"61"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.7045999765396118,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.7045999765396118,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.25099998712539673,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.012799999676644802,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/von-willebrand-factor","display_name":"von Willebrand factor","score":0.972000002861023},{"id":"https://openalex.org/keywords/liver-regeneration","display_name":"liver regeneration","score":0.7979999780654907},{"id":"https://openalex.org/keywords/hepatocellular-carcinoma","display_name":"hepatocellular carcinoma","score":0.8759999871253967},{"id":"https://openalex.org/keywords/hcc-recurrence","display_name":"HCC recurrence","score":0.9649999737739563},{"id":"https://openalex.org/keywords/partial-hepatectomy","display_name":"partial hepatectomy","score":0.9929999709129333},{"id":"https://openalex.org/keywords/vwf-ag","display_name":"VWF:Ag","score":0.7480000257492065},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.7210000157356262}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8409696817398071},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.7504796981811523},{"id":"https://openalex.org/C2778019345","wikidata":"https://www.wikidata.org/wiki/Q1148337","display_name":"Hepatocellular carcinoma","level":2,"score":0.7465944886207581},{"id":"https://openalex.org/C2776909242","wikidata":"https://www.wikidata.org/wiki/Q1514021","display_name":"Hepatectomy","level":3,"score":0.7145974636077881},{"id":"https://openalex.org/C2779394231","wikidata":"https://www.wikidata.org/wiki/Q412310","display_name":"Von Willebrand factor","level":3,"score":0.6656867265701294},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.6068723201751709},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.6029843091964722},{"id":"https://openalex.org/C2776795407","wikidata":"https://www.wikidata.org/wiki/Q19597761","display_name":"Liver regeneration","level":3,"score":0.5786400437355042},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5561794638633728},{"id":"https://openalex.org/C2992208098","wikidata":"https://www.wikidata.org/wiki/Q1359801","display_name":"Liver function","level":2,"score":0.4563806653022766},{"id":"https://openalex.org/C159110652","wikidata":"https://www.wikidata.org/wiki/Q17078201","display_name":"Resection","level":2,"score":0.4546416997909546},{"id":"https://openalex.org/C2992435398","wikidata":"https://www.wikidata.org/wiki/Q6934595","display_name":"Multicenter study","level":3,"score":0.4491066634654999},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.30182307958602905},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.18236392736434937},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000941","descriptor_name":"Antigens","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000941","descriptor_name":"Antigens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D001792","descriptor_name":"Blood Platelets","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001792","descriptor_name":"Blood Platelets","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006528","descriptor_name":"Carcinoma, Hepatocellular","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D006528","descriptor_name":"Carcinoma, Hepatocellular","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006528","descriptor_name":"Carcinoma, Hepatocellular","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D008115","descriptor_name":"Liver Regeneration","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014841","descriptor_name":"von Willebrand Factor","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D014841","descriptor_name":"von Willebrand Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3233/cbm-190168","doi":"https://doi.org/10.3233/cbm-190168","is_oa":false,"landing_page_url":"https://doi.org/10.3233/cbm-190168","pdf_url":null,"source":{"id":"https://openalex.org/S61994691","display_name":"Cancer Biomarkers","issn_l":"1574-0153","issn":["1574-0153","1875-8592"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Biomarkers","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12826445","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12826445/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12826445/pdf/cbm-26-cbm190168.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Biomark","raw_type":"Text"},{"id":"pmid:31322547","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31322547","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer biomarkers : section A of Disease markers","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:12826445","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12826445/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12826445/pdf/cbm-26-cbm190168.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Biomark","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G2669458714","display_name":"\u8840\u5c0f\u677f\u5185\u5728\u6027VEGF-A\u3092\u5206\u5b50\u6a19\u7684\u3068\u3059\u308b\u65b0\u898f\u5927\u8178\u764c\u6cbb\u7642\u306e\u81e8\u5e8a\u53ca\u3073\u5206\u5b50\u751f\u7269\u5b66\u7684\u7814\u7a76","funder_award_id":"18F16420","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G4293632225","display_name":"Analysis for pro grammed cell death of  anuclear platelets and erythrocytes for application of laboratory medicine","funder_award_id":"16H05229","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G4826302396","display_name":"Construction of A New Paradigm for Diagnosis and Treatment of Atherosclerosis Obliterans","funder_award_id":"18H02734","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G498710662","display_name":"The role of Endothelial miRNA in the regulation of vascular integrity","funder_award_id":"26293130","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G8408032566","display_name":"The role of p53 in atherosclerosis","funder_award_id":"18K19523","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2960799015.pdf","grobid_xml":"https://content.openalex.org/works/W2960799015.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W1489226586","https://openalex.org/W1500082363","https://openalex.org/W1555772259","https://openalex.org/W1933833491","https://openalex.org/W1963554573","https://openalex.org/W1968478912","https://openalex.org/W1968519475","https://openalex.org/W1976036895","https://openalex.org/W1980368013","https://openalex.org/W1999943742","https://openalex.org/W2002446745","https://openalex.org/W2007486557","https://openalex.org/W2014253619","https://openalex.org/W2020408101","https://openalex.org/W2022480783","https://openalex.org/W2045164759","https://openalex.org/W2048418340","https://openalex.org/W2052993149","https://openalex.org/W2062406657","https://openalex.org/W2063991251","https://openalex.org/W2068203605","https://openalex.org/W2071682406","https://openalex.org/W2073947187","https://openalex.org/W2096674194","https://openalex.org/W2104668592","https://openalex.org/W2129238955","https://openalex.org/W2155471756","https://openalex.org/W2285881565","https://openalex.org/W2288647707","https://openalex.org/W2291389434","https://openalex.org/W2394619618","https://openalex.org/W2586847824","https://openalex.org/W2747554157","https://openalex.org/W2766756278","https://openalex.org/W2769784848","https://openalex.org/W2809908124","https://openalex.org/W6629559040"],"related_works":["https://openalex.org/W4247701999","https://openalex.org/W2769784848","https://openalex.org/W2895307537","https://openalex.org/W2792939686","https://openalex.org/W2900449978","https://openalex.org/W4399805991","https://openalex.org/W3201222566","https://openalex.org/W3044171226","https://openalex.org/W3133506627","https://openalex.org/W4414542101"],"abstract_inverted_index":{"BACKGROUND":[0],"AND":[1],"AIMS:":[2],"A":[3,65],"striking":[4],"difference":[5],"has":[6,26],"been":[7],"observed":[8,101],"in":[9,34,55,84,105,110,172],"structure":[10],"and":[11,16,38,52,86,96,112,123,136,174],"functional":[12],"properties":[13,48],"between":[14],"plasma":[15,32],"platelet":[17,87],"von":[18],"Willebrand":[19],"factor":[20],"(VWF).":[21],"While":[22],"the":[23,47,106],"existing":[24],"evidence":[25],"revealed":[27],"a":[28,102,128,166,183],"clinical":[29],"relevance":[30],"of":[31,49,67,108,169],"VWF-Ag":[33,54,79,109,125,138,149,195],"liver":[35,94,117,188],"regeneration":[36],"(LR)":[37],"different":[39],"cancers,":[40],"this":[41],"study":[42,164],"was":[43,150],"designed":[44],"to":[45,142,152,181,199],"explore":[46],"intra-platelet":[50],"(IP)":[51],"serum":[53,85,111,122,135],"patients":[56,69,131,191],"with":[57,115,132,192],"hepatocellular":[58],"carcinoma":[59],"(HCC)":[60],"undergoing":[61,70],"partial":[62,71],"hepatectomy.":[63],"METHODS:":[64],"total":[66],"40":[68],"hepatectomy":[72],"were":[73,81,90,140,197],"prospectively":[74],"recruited":[75],"from":[76],"3":[77],"institutions.":[78],"concentrations":[80,139,196],"evaluated":[82],"mainly":[83],"extracts.":[88],"Patients":[89,114],"followed-up":[91],"for":[92],"postoperative":[93,116],"dysfunction":[95,118],"HCC":[97,145,157,202],"recurrence.":[98,146,158,203],"RESULTS:":[99],"We":[100],"post-resection":[103,134,155,187,194],"increase":[104],"concentration":[107],"platelet.":[113],"had":[119],"substantially":[120],"reduced":[121],"IP":[124,137,148,170],"concentrations.":[126],"After":[127],"2-year":[129],"follow-up,":[130],"higher":[133,193],"found":[141,198],"develop":[143],"early":[144,156,201],"Likewise,":[147],"able":[151],"independently":[153],"predict":[154],"CONCLUSION:":[159],"This":[160],"multicenter,":[161],"prospective,":[162],"pilot":[163],"demonstrates":[165],"bivalent":[167],"property":[168],"VWF":[171,179],"LR":[173],"oncological":[175],"outcome;":[176],"low":[177],"preoperative":[178],"appeared":[180],"have":[182,200],"negative":[184],"association":[185],"on":[186],"dysfunction,":[189],"whereas,":[190]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-07-23T00:00:00"}