{"id":"https://openalex.org/W29568342","doi":null,"title":"Renal function curves and control of body fluids and arterial pressure.","display_name":"Renal function curves and control of body fluids and arterial pressure.","publication_year":1990,"publication_date":"1990-01-01","ids":{"openalex":"https://openalex.org/W29568342","mag":"29568342","pmid":"https://pubmed.ncbi.nlm.nih.gov/2220403"},"language":"en","primary_location":{"id":"pmid:2220403","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2220403","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta physiologica Scandinavica. Supplementum","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080295190","display_name":"A C Guyton","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"A C Guyton","raw_affiliation_strings":["University of Mississippi Medical Center, Jackson"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Mississippi Medical Center, Jackson","institution_ids":["https://openalex.org/I29606459"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5080295190"],"corresponding_institution_ids":["https://openalex.org/I29606459"],"apc_list":null,"apc_paid":null,"fwci":0.3783,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.59192825,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"591","issue":null,"first_page":"107","last_page":"13"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.8730000257492065,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.8730000257492065,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.08990000188350677,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12075","display_name":"Sodium Intake and Health","score":0.01140000019222498,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/blood-pressure-regulation","display_name":"blood pressure regulation","score":0.8080000281333923},{"id":"https://openalex.org/keywords/body-fluid-regulation","display_name":"body fluid regulation","score":0.5740000009536743},{"id":"https://openalex.org/keywords/salt-intake","display_name":"salt intake","score":0.6700000166893005},{"id":"https://openalex.org/keywords/water-intake","display_name":"water intake","score":0.8429999947547913}],"concepts":[{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.6776425838470459},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.5895358920097351},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.4938364624977112},{"id":"https://openalex.org/C2776452961","wikidata":"https://www.wikidata.org/wiki/Q1940733","display_name":"Mean arterial pressure","level":4,"score":0.4456143379211426},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.44365787506103516},{"id":"https://openalex.org/C2781153586","wikidata":"https://www.wikidata.org/wiki/Q7241717","display_name":"Pressure control","level":2,"score":0.4128165543079376},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.39903727173805237},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.39552515745162964},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.3540995121002197},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3534390926361084},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2653467655181885},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.1332988440990448},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1083710789680481},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.0},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D001826","descriptor_name":"Body Fluids","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D007677","descriptor_name":"Kidney Function Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:2220403","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2220403","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta physiologica Scandinavica. Supplementum","raw_type":"Journal Article"},{"id":"mag:29568342","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2220403","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.4043000042438507,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W2164132449","https://openalex.org/W4245191120","https://openalex.org/W2046440947","https://openalex.org/W2400075415","https://openalex.org/W2613902198","https://openalex.org/W2619239534","https://openalex.org/W1980205834","https://openalex.org/W2129849056","https://openalex.org/W2138423109","https://openalex.org/W2528622423","https://openalex.org/W2426764224","https://openalex.org/W1655797917","https://openalex.org/W2066020760","https://openalex.org/W2156390359","https://openalex.org/W2604497814","https://openalex.org/W2142155021","https://openalex.org/W2616199912","https://openalex.org/W2502317923","https://openalex.org/W2150167537","https://openalex.org/W2020417824","https://openalex.org/W1503667350","https://openalex.org/W2045075067","https://openalex.org/W2487512931","https://openalex.org/W2102085814","https://openalex.org/W1559368759","https://openalex.org/W2146499587","https://openalex.org/W2766203900","https://openalex.org/W2141490966","https://openalex.org/W2144062218","https://openalex.org/W2066987620","https://openalex.org/W2597208355","https://openalex.org/W1965554885","https://openalex.org/W2146941357","https://openalex.org/W2149434929","https://openalex.org/W2625598332"],"related_works":["https://openalex.org/W1894092760","https://openalex.org/W80391022","https://openalex.org/W2126758468","https://openalex.org/W93836214","https://openalex.org/W2025255205","https://openalex.org/W12604848","https://openalex.org/W2321102243","https://openalex.org/W1856509968","https://openalex.org/W2418023770","https://openalex.org/W1987575276"],"abstract_inverted_index":{"The":[0,25],"purpose":[1],"of":[2,12,22,40,57,100,136,161],"this":[3,28,65,119],"paper":[4],"has":[5],"been":[6],"to":[7,122,129,146],"emphasize":[8],"the":[9,13,19,32,38,46,53,90,96,124,131,141,151,166],"extreme":[10],"importance":[11,29],"renal":[14,77,86,125,167],"function":[15,78,126,168],"curve":[16,79,127,169],"in":[17,157],"determining":[18],"long-term":[20,152,162],"level":[21,73],"arterial":[23,47,97,108,153,163],"pressure.":[24],"reason":[26],"for":[27,74,88,106],"is":[30],"that":[31,111],"renal-body":[33],"fluid-pressure":[34],"control":[35,114],"system":[36],"exhibits":[37],"phenomenon":[39],"\"infinite":[41],"feedback":[42,103],"gain\".":[43],"This":[44,85],"is,":[45],"pressure":[48,72,113,143,154,164],"will":[49],"stabilize":[50],"only":[51,68],"when":[52],"intake":[54,83,135],"and":[55,59,64,80,93,138],"output":[56],"water":[58,139],"salt":[60,82,137],"becomes":[61],"exactly":[62],"equal,":[63],"occurs":[66],"at":[67],"one":[69],"very":[70],"exact":[71],"any":[75,148,159],"given":[76,81],"level.":[84,155],"mechanism":[87,120],"controlling":[89,95,107],"body":[91],"fluids":[92],"simultaneously":[94],"pressure,":[98,109],"because":[99],"its":[101,134,171],"infinite":[102],"gain":[104],"capability":[105],"requires":[110],"other":[112,142],"mechanisms":[115,144],"must":[116],"interact":[117],"with":[118],"either":[121],"alter":[123],"or":[128,170],"make":[130],"animal":[132],"change":[133],"if":[140],"are":[145],"have":[147],"effect":[149],"on":[150],"Therefore,":[156],"virtually":[158],"analysis":[160],"regulation,":[165],"mathematical":[172],"equivalent":[173],"plays":[174],"a":[175],"central":[176],"role.":[177]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}