{"id":"https://openalex.org/W2956669871","doi":"https://doi.org/10.5021/ad.2019.31.4.403","title":"Polydeoxyribonucleotides Improve Diabetic Wound Healing in Mouse Animal Model for Experimental Validation","display_name":"Polydeoxyribonucleotides Improve Diabetic Wound Healing in Mouse Animal Model for Experimental Validation","publication_year":2019,"publication_date":"2019-01-01","ids":{"openalex":"https://openalex.org/W2956669871","doi":"https://doi.org/10.5021/ad.2019.31.4.403","mag":"2956669871","pmid":"https://pubmed.ncbi.nlm.nih.gov/33911618","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7992745"},"language":"en","primary_location":{"id":"doi:10.5021/ad.2019.31.4.403","doi":"https://doi.org/10.5021/ad.2019.31.4.403","is_oa":true,"landing_page_url":"https://doi.org/10.5021/ad.2019.31.4.403","pdf_url":"http://anndermatol.org/Synapse/Data/PDFData/0140AD/ad-31-403.pdf","source":{"id":"https://openalex.org/S182931825","display_name":"Annals of Dermatology","issn_l":"1013-9087","issn":["1013-9087","2005-3894"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","kci-registered","ki-jl-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4324001547","host_organization_name":"Korean Dermatological Association","host_organization_lineage":["https://openalex.org/P4324001547"],"host_organization_lineage_names":["Korean Dermatological Association"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Dermatology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://anndermatol.org/Synapse/Data/PDFData/0140AD/ad-31-403.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052328962","display_name":"Tae\u2010Rin Kwon","orcid":"https://orcid.org/0000-0002-9892-7714","observed_orcids":["https://orcid.org/0000-0002-9892-7714"]},"institutions":[{"id":"https://openalex.org/I4210153376","display_name":"Chung-Ang University Hospital","ror":"https://ror.org/04gr4mh63","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210153376","https://openalex.org/I4405261496","https://openalex.org/I67900169"]},{"id":"https://openalex.org/I67900169","display_name":"Chung-Ang University","ror":"https://ror.org/01r024a98","country_code":"KR","type":"education","lineage":["https://openalex.org/I67900169"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Tae-Rin Kwon","raw_affiliation_strings":["Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea"],"raw_orcid":"https://orcid.org/0000-0002-9892-7714","affiliations":[{"raw_affiliation_string":"Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I4210153376","https://openalex.org/I67900169"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024995454","display_name":"Sung Won Han","orcid":"https://orcid.org/0000-0002-0040-3542","observed_orcids":["https://orcid.org/0000-0002-0040-3542"]},"institutions":[{"id":"https://openalex.org/I4210153376","display_name":"Chung-Ang University Hospital","ror":"https://ror.org/04gr4mh63","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210153376","https://openalex.org/I4405261496","https://openalex.org/I67900169"]},{"id":"https://openalex.org/I67900169","display_name":"Chung-Ang University","ror":"https://ror.org/01r024a98","country_code":"KR","type":"education","lineage":["https://openalex.org/I67900169"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sung Won Han","raw_affiliation_strings":["Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea","Department of Medicine, Graduate School, Chung-Ang University, Seoul, Korea"],"raw_orcid":"https://orcid.org/0000-0002-0040-3542","affiliations":[{"raw_affiliation_string":"Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I4210153376","https://openalex.org/I67900169"]},{"raw_affiliation_string":"Department of Medicine, Graduate School, Chung-Ang University, Seoul, Korea","institution_ids":["https://openalex.org/I67900169"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011126782","display_name":"Jong Hwan Kim","orcid":"https://orcid.org/0000-0001-6201-9602","observed_orcids":["https://orcid.org/0000-0001-6201-9602"]},"institutions":[{"id":"https://openalex.org/I4210153376","display_name":"Chung-Ang University Hospital","ror":"https://ror.org/04gr4mh63","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210153376","https://openalex.org/I4405261496","https://openalex.org/I67900169"]},{"id":"https://openalex.org/I67900169","display_name":"Chung-Ang University","ror":"https://ror.org/01r024a98","country_code":"KR","type":"education","lineage":["https://openalex.org/I67900169"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jong Hwan Kim","raw_affiliation_strings":["Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea","Department of Medicine, Graduate School, Chung-Ang University, Seoul, Korea"],"raw_orcid":"https://orcid.org/0000-0001-6201-9602","affiliations":[{"raw_affiliation_string":"Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I4210153376","https://openalex.org/I67900169"]},{"raw_affiliation_string":"Department of Medicine, Graduate School, Chung-Ang University, Seoul, Korea","institution_ids":["https://openalex.org/I67900169"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101448833","display_name":"Byung Chul Lee","orcid":"https://orcid.org/0000-0002-6858-4853","observed_orcids":["https://orcid.org/0000-0002-6858-4853"]},"institutions":[{"id":"https://openalex.org/I4210153376","display_name":"Chung-Ang University Hospital","ror":"https://ror.org/04gr4mh63","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210153376","https://openalex.org/I4405261496","https://openalex.org/I67900169"]},{"id":"https://openalex.org/I67900169","display_name":"Chung-Ang University","ror":"https://ror.org/01r024a98","country_code":"KR","type":"education","lineage":["https://openalex.org/I67900169"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Byung Chul Lee","raw_affiliation_strings":["Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea","Department of Medicine, Graduate School, Chung-Ang University, Seoul, Korea"],"raw_orcid":"https://orcid.org/0000-0002-6858-4853","affiliations":[{"raw_affiliation_string":"Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I4210153376","https://openalex.org/I67900169"]},{"raw_affiliation_string":"Department of Medicine, Graduate School, Chung-Ang University, Seoul, Korea","institution_ids":["https://openalex.org/I67900169"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100610521","display_name":"Jae Min Kim","orcid":"https://orcid.org/0000-0001-7333-3883","observed_orcids":["https://orcid.org/0000-0001-7333-3883"]},"institutions":[{"id":"https://openalex.org/I4210153376","display_name":"Chung-Ang University Hospital","ror":"https://ror.org/04gr4mh63","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210153376","https://openalex.org/I4405261496","https://openalex.org/I67900169"]},{"id":"https://openalex.org/I67900169","display_name":"Chung-Ang University","ror":"https://ror.org/01r024a98","country_code":"KR","type":"education","lineage":["https://openalex.org/I67900169"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jae Min Kim","raw_affiliation_strings":["Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea","Department of Medicine, Graduate School, Chung-Ang University, Seoul, Korea"],"raw_orcid":"https://orcid.org/0000-0001-7333-3883","affiliations":[{"raw_affiliation_string":"Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I4210153376","https://openalex.org/I67900169"]},{"raw_affiliation_string":"Department of Medicine, Graduate School, Chung-Ang University, Seoul, Korea","institution_ids":["https://openalex.org/I67900169"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057549183","display_name":"Ji Yeon Hong","orcid":"https://orcid.org/0000-0002-5632-8449","observed_orcids":["https://orcid.org/0000-0002-5632-8449","https://orcid.org/0000-0003-0163-864X"]},"institutions":[{"id":"https://openalex.org/I4210153376","display_name":"Chung-Ang University Hospital","ror":"https://ror.org/04gr4mh63","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210153376","https://openalex.org/I4405261496","https://openalex.org/I67900169"]},{"id":"https://openalex.org/I67900169","display_name":"Chung-Ang University","ror":"https://ror.org/01r024a98","country_code":"KR","type":"education","lineage":["https://openalex.org/I67900169"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Ji Yeon Hong","raw_affiliation_strings":["Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea"],"raw_orcid":"https://orcid.org/0000-0002-5632-8449","affiliations":[{"raw_affiliation_string":"Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I4210153376","https://openalex.org/I67900169"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100661074","display_name":"Beom Joon Kim","orcid":"https://orcid.org/0000-0003-2320-7621","observed_orcids":["https://orcid.org/0000-0003-2320-7621","https://orcid.org/0000-0002-2719-3012"]},"institutions":[{"id":"https://openalex.org/I4210153376","display_name":"Chung-Ang University Hospital","ror":"https://ror.org/04gr4mh63","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210153376","https://openalex.org/I4405261496","https://openalex.org/I67900169"]},{"id":"https://openalex.org/I67900169","display_name":"Chung-Ang University","ror":"https://ror.org/01r024a98","country_code":"KR","type":"education","lineage":["https://openalex.org/I67900169"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Beom Joon Kim","raw_affiliation_strings":["Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea","Department of Medicine, Graduate School, Chung-Ang University, Seoul, Korea"],"raw_orcid":"https://orcid.org/0000-0003-2320-7621","affiliations":[{"raw_affiliation_string":"Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I4210153376","https://openalex.org/I67900169"]},{"raw_affiliation_string":"Department of Medicine, Graduate School, Chung-Ang University, Seoul, Korea","institution_ids":["https://openalex.org/I67900169"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5100661074"],"corresponding_institution_ids":["https://openalex.org/I4210153376","https://openalex.org/I67900169"],"apc_list":null,"apc_paid":null,"fwci":2.122,"has_fulltext":true,"cited_by_count":30,"citation_normalized_percentile":{"value":0.86309491,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"31","issue":"4","first_page":"403","last_page":"403"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11227","display_name":"Diabetic Foot Ulcer Assessment and Management","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11172","display_name":"Dermatologic Treatments and Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polydeoxyribonucleotide","display_name":"polydeoxyribonucleotide","score":0.9850000143051147},{"id":"https://openalex.org/keywords/diabetic-wound-healing","display_name":"diabetic wound healing","score":0.8820000290870667},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.8330000042915344},{"id":"https://openalex.org/keywords/db-db-mice","display_name":"db/db mice","score":0.8989999890327454},{"id":"https://openalex.org/keywords/intradermal-injection","display_name":"intradermal injection","score":0.921999990940094},{"id":"https://openalex.org/keywords/vascular-endothelial-growth-factor","display_name":"vascular endothelial growth factor","score":0.8679999709129333},{"id":"https://openalex.org/keywords/collagen-synthesis","display_name":"collagen synthesis","score":0.8859999775886536},{"id":"https://openalex.org/keywords/epidermal-regeneration","display_name":"epidermal regeneration","score":0.8270000219345093},{"id":"https://openalex.org/keywords/delayed-wound-healing","display_name":"delayed wound healing","score":0.7799999713897705}],"concepts":[{"id":"https://openalex.org/C2780269544","wikidata":"https://www.wikidata.org/wiki/Q1509074","display_name":"Wound healing","level":2,"score":0.8884471654891968},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8317335844039917},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.7713021039962769},{"id":"https://openalex.org/C2777624698","wikidata":"https://www.wikidata.org/wiki/Q505531","display_name":"Dermis","level":2,"score":0.6994370818138123},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.5003602504730225},{"id":"https://openalex.org/C2778271429","wikidata":"https://www.wikidata.org/wiki/Q1281049","display_name":"Neovascularization","level":3,"score":0.4676755368709564},{"id":"https://openalex.org/C2778939058","wikidata":"https://www.wikidata.org/wiki/Q4046167","display_name":"CD31","level":3,"score":0.43577584624290466},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.33038491010665894},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2621692717075348},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.13801315426826477},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.08171945810317993},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.5021/ad.2019.31.4.403","doi":"https://doi.org/10.5021/ad.2019.31.4.403","is_oa":true,"landing_page_url":"https://doi.org/10.5021/ad.2019.31.4.403","pdf_url":"http://anndermatol.org/Synapse/Data/PDFData/0140AD/ad-31-403.pdf","source":{"id":"https://openalex.org/S182931825","display_name":"Annals of Dermatology","issn_l":"1013-9087","issn":["1013-9087","2005-3894"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","kci-registered","ki-jl-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4324001547","host_organization_name":"Korean Dermatological Association","host_organization_lineage":["https://openalex.org/P4324001547"],"host_organization_lineage_names":["Korean Dermatological Association"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Dermatology","raw_type":"journal-article"},{"id":"pmid:33911618","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33911618","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of dermatology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7992745","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7992745/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ann Dermatol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.5021/ad.2019.31.4.403","doi":"https://doi.org/10.5021/ad.2019.31.4.403","is_oa":true,"landing_page_url":"https://doi.org/10.5021/ad.2019.31.4.403","pdf_url":"http://anndermatol.org/Synapse/Data/PDFData/0140AD/ad-31-403.pdf","source":{"id":"https://openalex.org/S182931825","display_name":"Annals of Dermatology","issn_l":"1013-9087","issn":["1013-9087","2005-3894"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","kci-registered","ki-jl-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4324001547","host_organization_name":"Korean Dermatological Association","host_organization_lineage":["https://openalex.org/P4324001547"],"host_organization_lineage_names":["Korean Dermatological Association"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Dermatology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2956669871.pdf","grobid_xml":"https://content.openalex.org/works/W2956669871.grobid-xml"},"referenced_works_count":26,"referenced_works":["https://openalex.org/W1214867471","https://openalex.org/W1520623323","https://openalex.org/W1949832432","https://openalex.org/W1969806743","https://openalex.org/W1975304771","https://openalex.org/W1986185314","https://openalex.org/W1986397614","https://openalex.org/W1986459596","https://openalex.org/W2015613680","https://openalex.org/W2035107225","https://openalex.org/W2062269302","https://openalex.org/W2073665284","https://openalex.org/W2086541144","https://openalex.org/W2101004085","https://openalex.org/W2105922835","https://openalex.org/W2109062406","https://openalex.org/W2110051960","https://openalex.org/W2115951554","https://openalex.org/W2137124126","https://openalex.org/W2152711442","https://openalex.org/W2263378377","https://openalex.org/W2574904481","https://openalex.org/W2592719802","https://openalex.org/W2602864067","https://openalex.org/W2610140566","https://openalex.org/W2743752524"],"related_works":["https://openalex.org/W2073665284","https://openalex.org/W4317423568","https://openalex.org/W3208112815","https://openalex.org/W3092170760","https://openalex.org/W4213117213","https://openalex.org/W4408857209","https://openalex.org/W2806513996","https://openalex.org/W2766508762","https://openalex.org/W3005071615","https://openalex.org/W2012189513"],"abstract_inverted_index":{"BACKGROUND:":[0],"Wound":[1],"healing":[2,12,40,71,81,192,206],"mechanisms":[3],"is":[4],"believed":[5],"to":[6,10,37,112],"have":[7],"effects":[8],"similar":[9],"wound":[11,39,64,70,80,114,133,143,191,205],"disorders":[13],"in":[14,53,172,186,208],"diabetic":[15],"patients,":[16],"including":[17],"abnormal":[18],"inflammatory":[19],"cells,":[20],"angiogenesis":[21,33],"disorders,":[22],"and":[23,31,135,137,145,152,169,214],"reduced":[24],"collagen":[25,170],"synthesis.":[26],"Therefore,":[27,43],"reestablishment":[28],"of":[29,73,89,92,163,189],"structural":[30],"promoted":[32],"could":[34,55],"be":[35,56],"beneficial":[36],"promote":[38],"process.":[41],"OBJECTIVE:":[42],"we":[44,67,83],"investigated":[45],"whether":[46],"the":[47,109,113,173,178,187],"polydeoxyribonucleotide":[48],"(PDRN)":[49],"that":[50,85,126,182,200],"was":[51,104,184],"self-production":[52],"Korea,":[54],"useful":[57],"as":[58],"an":[59,161],"intradermal":[60],"injection":[61],"for":[62,69,115],"promoting":[63],"healing.":[65],"Also,":[66],"validate":[68],"effect":[72,207],"PDRN":[74,86,96,130,174,183,202],"using":[75],"healing-impaired":[76],"(db/db)":[77],"mice.":[78],"METHODS:":[79],"assay,":[82],"observed":[84],"stimulated":[87],"closure":[88,134],"wounded":[90],"monolayers":[91],"human":[93],"fibroblast":[94],"cells.":[95],"(8.25":[97],"mg/ml)":[98],"or":[99],"phosphate-buffered":[100],"saline":[101],"(0.9%":[102],"NaCl)":[103],"injected":[105],"once":[106],"daily":[107],"into":[108],"dermis":[110],"adjacent":[111],"12":[116,153],"days":[117,154],"after":[118,155],"skin":[119,156],"injury.":[120,157],"RESULTS:":[121],"Time":[122],"course":[123],"observations":[124],"revealed":[125],"mice":[127],"treated":[128],"with":[129,177,212],"showed":[131,160],"accelerated":[132],"epidermal":[136],"dermal":[138],"regeneration,":[139],"enhanced":[140],"angiogenesis.":[141,217],"The":[142],"area":[144],"depth":[146],"decreased":[147],"at":[148],"3,":[149],"6,":[150],"9,":[151],"Histological":[158],"evaluation":[159],"increase":[162],"vascular":[164],"endothelial":[165],"growth":[166],"factor,":[167],"CD31,":[168],"fibers":[171],"group":[175],"compared":[176],"control":[179],"group,":[180],"indicating":[181],"effective":[185],"treatment":[188],"delayed":[190],"caused":[193],"by":[194],"diabetes.":[195],"CONCLUSION:":[196],"This":[197],"study":[198],"suggests":[199],"our":[201],"has":[203],"a":[204],"transgenic":[209],"animal":[210],"models":[211],"cells":[213],"diabetes":[215],"through":[216]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2019-07-23T00:00:00"}
