{"id":"https://openalex.org/W2955931069","doi":"https://doi.org/10.1088/1755-1315/292/1/012031","title":"Association of CAPN10 SNP-19 (rs3842570) Polymorphism on Fasting Plasma Glucose, Blood Pressure and Body Mass Index of Javanese Type-2 Diabetes Patients","display_name":"Association of CAPN10 SNP-19 (rs3842570) Polymorphism on Fasting Plasma Glucose, Blood Pressure and Body Mass Index of Javanese Type-2 Diabetes Patients","publication_year":2019,"publication_date":"2019-06-01","ids":{"openalex":"https://openalex.org/W2955931069","doi":"https://doi.org/10.1088/1755-1315/292/1/012031","mag":"2955931069"},"language":"en","primary_location":{"id":"doi:10.1088/1755-1315/292/1/012031","doi":"https://doi.org/10.1088/1755-1315/292/1/012031","is_oa":true,"landing_page_url":"https://doi.org/10.1088/1755-1315/292/1/012031","pdf_url":"https://iopscience.iop.org/article/10.1088/1755-1315/292/1/012031/pdf","source":{"id":"https://openalex.org/S4210195883","display_name":"IOP Conference Series Earth and Environmental Science","issn_l":"1755-1315","issn":["1755-1315","1755-1307"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320083","host_organization_name":"IOP Publishing","host_organization_lineage":["https://openalex.org/P4310320083","https://openalex.org/P4310311669"],"host_organization_lineage_names":["IOP Publishing","Institute of Physics"],"type":"conference"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IOP Conference Series: Earth and Environmental Science","raw_type":"journal-article"},"volume":null,"type":"conference-paper","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://iopscience.iop.org/article/10.1088/1755-1315/292/1/012031/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078972565","display_name":"Yanuarita Tursinawati","orcid":"https://orcid.org/0000-0003-4634-9761","observed_orcids":["https://orcid.org/0000-0003-4634-9761"]},"institutions":[{"id":"https://openalex.org/I4210159899","display_name":"Universitas Muhammadiyah Semarang","ror":"https://ror.org/05hra0856","country_code":"ID","type":"education","lineage":["https://openalex.org/I4210159899"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Y Tursinawati","raw_affiliation_strings":["Biomedical Science Departement, Faculty of Medicine, University of Muhammadiyah Semarang, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Science Departement, Faculty of Medicine, University of Muhammadiyah Semarang, Indonesia","institution_ids":["https://openalex.org/I4210159899"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054620127","display_name":"Arum Kartikadewi","orcid":"https://orcid.org/0000-0002-8917-0668","observed_orcids":["https://orcid.org/0000-0002-8917-0668"]},"institutions":[{"id":"https://openalex.org/I4210159899","display_name":"Universitas Muhammadiyah Semarang","ror":"https://ror.org/05hra0856","country_code":"ID","type":"education","lineage":["https://openalex.org/I4210159899"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"A Kartikadewi","raw_affiliation_strings":["Biomedical Science Departement, Faculty of Medicine, University of Muhammadiyah Semarang, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Science Departement, Faculty of Medicine, University of Muhammadiyah Semarang, Indonesia","institution_ids":["https://openalex.org/I4210159899"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021705305","display_name":"Rifqi Fauzan Hakim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210159899","display_name":"Universitas Muhammadiyah Semarang","ror":"https://ror.org/05hra0856","country_code":"ID","type":"education","lineage":["https://openalex.org/I4210159899"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"R F Hakim","raw_affiliation_strings":["Undergraduate student, Faculty of Medicine, University of Muhammadiyah Semarang, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Undergraduate student, Faculty of Medicine, University of Muhammadiyah Semarang, Indonesia","institution_ids":["https://openalex.org/I4210159899"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210159899"],"apc_list":null,"apc_paid":null,"fwci":8.367,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.96050466,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"292","issue":"1","first_page":"012031","last_page":"012031"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.8521000146865845,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.8521000146865845,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13637","display_name":"Calpain Protease Function and Regulation","score":0.10939999669790268,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.00800000037997961,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/capn10","display_name":"CAPN10","score":0.9829999804496765},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.8399999737739563},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9890000224113464},{"id":"https://openalex.org/keywords/fasting-blood-glucose","display_name":"fasting blood glucose","score":0.972000002861023},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"blood pressure","score":0.9990000128746033},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":1.0},{"id":"https://openalex.org/keywords/javanese-population","display_name":"Javanese population","score":0.8330000042915344},{"id":"https://openalex.org/keywords/genetic-association","display_name":"genetic association","score":0.7540000081062317},{"id":"https://openalex.org/keywords/genotype-distribution","display_name":"genotype distribution","score":0.3230000138282776}],"concepts":[{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.6877129077911377},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.686387300491333},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.684400200843811},{"id":"https://openalex.org/C2910068830","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 Diabetes Mellitus","level":3,"score":0.670459508895874},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.5816242694854736},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5500730276107788},{"id":"https://openalex.org/C139275648","wikidata":"https://www.wikidata.org/wiki/Q17134011","display_name":"SNP","level":5,"score":0.5462198257446289},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.519124448299408},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4809912443161011},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.46553507447242737},{"id":"https://openalex.org/C149737253","wikidata":"https://www.wikidata.org/wiki/Q3240252","display_name":"Polymorphism (computer science)","level":4,"score":0.4577341377735138},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.412314772605896},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.36924201250076294},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.2584190368652344},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.25302523374557495},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.21698084473609924},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07586726546287537}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1088/1755-1315/292/1/012031","doi":"https://doi.org/10.1088/1755-1315/292/1/012031","is_oa":true,"landing_page_url":"https://doi.org/10.1088/1755-1315/292/1/012031","pdf_url":"https://iopscience.iop.org/article/10.1088/1755-1315/292/1/012031/pdf","source":{"id":"https://openalex.org/S4210195883","display_name":"IOP Conference Series Earth and Environmental Science","issn_l":"1755-1315","issn":["1755-1315","1755-1307"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320083","host_organization_name":"IOP Publishing","host_organization_lineage":["https://openalex.org/P4310320083","https://openalex.org/P4310311669"],"host_organization_lineage_names":["IOP Publishing","Institute of Physics"],"type":"conference"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IOP Conference Series: Earth and Environmental Science","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1088/1755-1315/292/1/012031","doi":"https://doi.org/10.1088/1755-1315/292/1/012031","is_oa":true,"landing_page_url":"https://doi.org/10.1088/1755-1315/292/1/012031","pdf_url":"https://iopscience.iop.org/article/10.1088/1755-1315/292/1/012031/pdf","source":{"id":"https://openalex.org/S4210195883","display_name":"IOP Conference Series Earth and Environmental Science","issn_l":"1755-1315","issn":["1755-1315","1755-1307"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320083","host_organization_name":"IOP Publishing","host_organization_lineage":["https://openalex.org/P4310320083","https://openalex.org/P4310311669"],"host_organization_lineage_names":["IOP Publishing","Institute of Physics"],"type":"conference"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IOP Conference Series: Earth and Environmental Science","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2955931069.pdf","grobid_xml":"https://content.openalex.org/works/W2955931069.grobid-xml"},"referenced_works_count":15,"referenced_works":["https://openalex.org/W1903695539","https://openalex.org/W1978493049","https://openalex.org/W1982539838","https://openalex.org/W1986822919","https://openalex.org/W2011523744","https://openalex.org/W2038429516","https://openalex.org/W2047645921","https://openalex.org/W2062922086","https://openalex.org/W2091717229","https://openalex.org/W2102758116","https://openalex.org/W2134118573","https://openalex.org/W2301602947","https://openalex.org/W2334275904","https://openalex.org/W2595743149","https://openalex.org/W6639647357"],"related_works":["https://openalex.org/W3038861232","https://openalex.org/W4387103305","https://openalex.org/W3082071461","https://openalex.org/W4280540273","https://openalex.org/W2363691264","https://openalex.org/W2340707207","https://openalex.org/W1965706951","https://openalex.org/W3031403240","https://openalex.org/W2085807537","https://openalex.org/W2768396411"],"abstract_inverted_index":{"Polymorphism":[0],"of":[1,11,26,34,60,77,94,136,145,198],"CAPN10":[2,44,95,185],"has":[3],"been":[4],"reported":[5],"to":[6,38,192],"be":[7],"responsible":[8],"for":[9],"risk":[10],"Type":[12],"2":[13],"Diabetes":[14],"Mellitus":[15],"(T2DM),":[16],"and":[17,30,55,103,113,154,174,196],"CAPN":[18],"10":[19],"SNP-19":[20,45,186],"(rs3842570)":[21,46,187],"is":[22],"associated":[23],"with":[24,151,168,176],"elevation":[25],"blood":[27,52,146],"glucose,":[28],"obesity,":[29],"metabolic":[31],"syndrome.":[32],"Aims":[33],"this":[35],"study":[36,65],"are":[37],"analyze":[39],"the":[40,126,129,133,142],"association":[41,109,162],"between":[42,110,163],"polymorphism":[43,93,164,188],"on":[47],"fasting":[48],"plasma":[49],"glucose":[50],"(FPG),":[51],"pressure":[53,147],"(BP)":[54],"body":[56],"mass":[57],"index":[58],"(BMI)":[59],"Javanese":[61,78,199],"T2DM":[62,69,80,127,166,200],"patients.":[63,201],"The":[64,92,108],"sample":[66],"comprised":[67],"107":[68,74],"subjects":[70,76,81],"as":[71,73],"well":[72],"healthy":[75],"origin.":[79],"were":[82,106],"obtained":[83],"from":[84],"several":[85],"Primary":[86],"Public":[87],"Health":[88],"Centers":[89],"in":[90,115,165],"Semarang.":[91],"SNP19":[96],"was":[97,119,148,159],"examined":[98],"using":[99,121],"PCR.":[100],"FPG,":[101,111,169,194],"BP,":[102,112,171,195],"BMI":[104,114,139,175,197],"also":[105],"examined.":[107],"each":[116],"genotype":[117,131,150],"class":[118],"analyzed":[120],"Kruskal":[122],"Wallis":[123],"test.":[124],"In":[125,183],"group,":[128],"2R/3R":[130],"had":[132],"highest":[134,143],"mean":[135,144],"FPG":[137],"(138,42\u00b16,77mg/dl),":[138],"(26,49\u00b10,41).":[140],"However,":[141],"2R/2R":[149],"systolic":[152,170],"142,00\u00b17,27mmHg":[153],"diastolic":[155,172],"83,11\u00b1":[156],"3,":[157],"17mmHg.There":[158],"no":[160],"significant":[161],"group":[167],"BP":[173],"p-value":[177],"0,563;":[178],"0,734;":[179],"0,939;":[180],"0,087,":[181],"respectively.":[182],"conclusion,":[184],"does":[189],"not":[190],"contribute":[191],"elevating":[193]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2}],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2019-07-12T00:00:00"}