{"id":"https://openalex.org/W2955435545","doi":"https://doi.org/10.1080/07315724.2019.1627955","title":"Hepatoprotective Effect of Probiotic Lactobacillus rhamnosus GG Through the Modulation of Gut Permeability and Inflammasomes in a Model of Alcoholic Liver Disease in Zebrafish","display_name":"Hepatoprotective Effect of Probiotic Lactobacillus rhamnosus GG Through the Modulation of Gut Permeability and Inflammasomes in a Model of Alcoholic Liver Disease in Zebrafish","publication_year":2019,"publication_date":"2019-06-26","ids":{"openalex":"https://openalex.org/W2955435545","doi":"https://doi.org/10.1080/07315724.2019.1627955","mag":"2955435545","pmid":"https://pubmed.ncbi.nlm.nih.gov/31241423"},"language":"en","primary_location":{"id":"doi:10.1080/07315724.2019.1627955","doi":"https://doi.org/10.1080/07315724.2019.1627955","is_oa":false,"landing_page_url":"https://doi.org/10.1080/07315724.2019.1627955","pdf_url":null,"source":{"id":"https://openalex.org/S102275522","display_name":"Journal of the American College of Nutrition","issn_l":"0731-5724","issn":["0731-5724","1541-1087"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Nutrition","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2955435545"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037603233","display_name":"Juliana Paula Bruch Bertani","orcid":"https://orcid.org/0000-0002-2427-2858","observed_orcids":["https://orcid.org/0000-0002-2427-2858"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]},{"id":"https://openalex.org/I4210097146","display_name":"Hospital de Cl\u00ednicas de Porto Alegre","ror":"https://ror.org/010we4y38","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210097146"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Juliana Paula Bruch-Bertani","raw_affiliation_strings":["Experimental Laboratory of Hepatology and Gastroenterology, Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;","Post Graduate Program in Gastroenterology and Hepatology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Laboratory of Hepatology and Gastroenterology, Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;","institution_ids":["https://openalex.org/I4210097146"]},{"raw_affiliation_string":"Post Graduate Program in Gastroenterology and Hepatology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103080012","display_name":"Carolina Uribe Cruz","orcid":"https://orcid.org/0000-0002-0526-3067","observed_orcids":["https://orcid.org/0000-0002-0526-3067"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]},{"id":"https://openalex.org/I4210097146","display_name":"Hospital de Cl\u00ednicas de Porto Alegre","ror":"https://ror.org/010we4y38","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210097146"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Carolina Uribe-Cruz","raw_affiliation_strings":["Experimental Laboratory of Hepatology and Gastroenterology, Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;","Post Graduate Program in Gastroenterology and Hepatology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Laboratory of Hepatology and Gastroenterology, Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;","institution_ids":["https://openalex.org/I4210097146"]},{"raw_affiliation_string":"Post Graduate Program in Gastroenterology and Hepatology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029489947","display_name":"Amanda Pasqualotto","orcid":"https://orcid.org/0000-0002-8273-3499","observed_orcids":["https://orcid.org/0000-0002-8273-3499"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]},{"id":"https://openalex.org/I4210097146","display_name":"Hospital de Cl\u00ednicas de Porto Alegre","ror":"https://ror.org/010we4y38","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210097146"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Amanda Pasqualotto","raw_affiliation_strings":["Experimental Laboratory of Hepatology and Gastroenterology, Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;","Post Graduate Program in Gastroenterology and Hepatology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Laboratory of Hepatology and Gastroenterology, Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;","institution_ids":["https://openalex.org/I4210097146"]},{"raw_affiliation_string":"Post Graduate Program in Gastroenterology and Hepatology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011509066","display_name":"Larisse Longo","orcid":"https://orcid.org/0000-0002-4453-7227","observed_orcids":["https://orcid.org/0000-0002-4453-7227"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]},{"id":"https://openalex.org/I4210097146","display_name":"Hospital de Cl\u00ednicas de Porto Alegre","ror":"https://ror.org/010we4y38","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210097146"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Larisse Longo","raw_affiliation_strings":["Experimental Laboratory of Hepatology and Gastroenterology, Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;","Post Graduate Program in Gastroenterology and Hepatology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Laboratory of Hepatology and Gastroenterology, Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;","institution_ids":["https://openalex.org/I4210097146"]},{"raw_affiliation_string":"Post Graduate Program in Gastroenterology and Hepatology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061557705","display_name":"Raquel Ayres","orcid":"https://orcid.org/0000-0002-7154-0501","observed_orcids":["https://orcid.org/0000-0002-7154-0501"]},"institutions":[{"id":"https://openalex.org/I4210097146","display_name":"Hospital de Cl\u00ednicas de Porto Alegre","ror":"https://ror.org/010we4y38","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210097146"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Raquel Ayres","raw_affiliation_strings":["Experimental Laboratory of Hepatology and Gastroenterology, Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Laboratory of Hepatology and Gastroenterology, Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;","institution_ids":["https://openalex.org/I4210097146"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016664576","display_name":"Carolina Bortolin Beskow","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]},{"id":"https://openalex.org/I4210097146","display_name":"Hospital de Cl\u00ednicas de Porto Alegre","ror":"https://ror.org/010we4y38","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210097146"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Carolina Bortolin Beskow","raw_affiliation_strings":["Experimental Laboratory of Hepatology and Gastroenterology, Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;","Post Graduate Program in Gastroenterology and Hepatology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Laboratory of Hepatology and Gastroenterology, Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;","institution_ids":["https://openalex.org/I4210097146"]},{"raw_affiliation_string":"Post Graduate Program in Gastroenterology and Hepatology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049852963","display_name":"Afonso Lu\u00eds Barth","orcid":"https://orcid.org/0000-0002-7969-3908","observed_orcids":["https://orcid.org/0000-0002-7969-3908"]},"institutions":[{"id":"https://openalex.org/I4210097146","display_name":"Hospital de Cl\u00ednicas de Porto Alegre","ror":"https://ror.org/010we4y38","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210097146"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Afonso Luis Barth","raw_affiliation_strings":["Research Laboratory on Bacterial Resistance (LABRESIS), Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Laboratory on Bacterial Resistance (LABRESIS), Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;","institution_ids":["https://openalex.org/I4210097146"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078369995","display_name":"Daiana de Lima-Morales","orcid":"https://orcid.org/0000-0002-7465-3974","observed_orcids":["https://orcid.org/0000-0002-7465-3974"]},"institutions":[{"id":"https://openalex.org/I4210097146","display_name":"Hospital de Cl\u00ednicas de Porto Alegre","ror":"https://ror.org/010we4y38","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210097146"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Daiana Lima-Morales","raw_affiliation_strings":["Research Laboratory on Bacterial Resistance (LABRESIS), Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Laboratory on Bacterial Resistance (LABRESIS), Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;","institution_ids":["https://openalex.org/I4210097146"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024842900","display_name":"F\u00e1bio Meurer","orcid":"https://orcid.org/0000-0002-8389-9888","observed_orcids":["https://orcid.org/0000-0002-8389-9888"]},"institutions":[{"id":"https://openalex.org/I52418104","display_name":"Universidade Federal do Paran\u00e1","ror":"https://ror.org/05syd6y78","country_code":"BR","type":"education","lineage":["https://openalex.org/I52418104"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"F\u00e1bio Meurer","raw_affiliation_strings":["Post Graduate Program in Sustainable Development of Aquaculture, Universidade Federal do Paran\u00e1, Campus de Palotina, Paran\u00e1, Brazil;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Post Graduate Program in Sustainable Development of Aquaculture, Universidade Federal do Paran\u00e1, Campus de Palotina, Paran\u00e1, Brazil;","institution_ids":["https://openalex.org/I52418104"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085020360","display_name":"Gabriel Tayguara Silveira Guerreiro","orcid":"https://orcid.org/0000-0002-0550-4561","observed_orcids":["https://orcid.org/0000-0002-0550-4561"]},"institutions":[{"id":"https://openalex.org/I4210097146","display_name":"Hospital de Cl\u00ednicas de Porto Alegre","ror":"https://ror.org/010we4y38","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210097146"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Gabriel Tayguara Silveira Guerreiro","raw_affiliation_strings":["Experimental Laboratory of Hepatology and Gastroenterology, Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Laboratory of Hepatology and Gastroenterology, Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;","institution_ids":["https://openalex.org/I4210097146"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059405802","display_name":"Themis Reverbel da Silveira","orcid":"https://orcid.org/0000-0001-9867-8650","observed_orcids":["https://orcid.org/0000-0001-9867-8650"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]},{"id":"https://openalex.org/I4210097146","display_name":"Hospital de Cl\u00ednicas de Porto Alegre","ror":"https://ror.org/010we4y38","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210097146"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Themis Reverbel da Silveira","raw_affiliation_strings":["Experimental Laboratory of Hepatology and Gastroenterology, Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;","Post Graduate Program in Gastroenterology and Hepatology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Laboratory of Hepatology and Gastroenterology, Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;","institution_ids":["https://openalex.org/I4210097146"]},{"raw_affiliation_string":"Post Graduate Program in Gastroenterology and Hepatology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037830101","display_name":"M\u00e1rio Reis \u00c1lvares\u2010da\u2010Silva","orcid":"https://orcid.org/0000-0002-5001-246X","observed_orcids":["https://orcid.org/0000-0002-5001-246X"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]},{"id":"https://openalex.org/I4210097146","display_name":"Hospital de Cl\u00ednicas de Porto Alegre","ror":"https://ror.org/010we4y38","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210097146"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"M\u00e1rio Reis \u00c1lvares-da-Silva","raw_affiliation_strings":["Department of Internal Medicine, Gastroenterology and Hepatology Unit. School of Medicine, UFRGS. Gastroenterology and Hepatology Division, HCPA, Porto Alegre, Brazil","Experimental Laboratory of Hepatology and Gastroenterology, Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;","Post Graduate Program in Gastroenterology and Hepatology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Gastroenterology and Hepatology Unit. School of Medicine, UFRGS. Gastroenterology and Hepatology Division, HCPA, Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723","https://openalex.org/I4210097146"]},{"raw_affiliation_string":"Experimental Laboratory of Hepatology and Gastroenterology, Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;","institution_ids":["https://openalex.org/I4210097146"]},{"raw_affiliation_string":"Post Graduate Program in Gastroenterology and Hepatology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil;","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049975320","display_name":"Valesca Dall\u2019Alba","orcid":"https://orcid.org/0000-0002-8896-3199","observed_orcids":["https://orcid.org/0000-0002-8896-3199"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]},{"id":"https://openalex.org/I4210097146","display_name":"Hospital de Cl\u00ednicas de Porto Alegre","ror":"https://ror.org/010we4y38","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210097146"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Valesca Dall\u2019Alba","raw_affiliation_strings":["Department of Nutrition. School of Medicine, UFRGS. Nutrition Division. Hospital de Cl\u00ednicas de Porto Alegre, UFRGS. Porto Alegre, Brazil","Experimental Laboratory of Hepatology and Gastroenterology, Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;","Post Graduate Program in Gastroenterology and Hepatology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition. School of Medicine, UFRGS. Nutrition Division. Hospital de Cl\u00ednicas de Porto Alegre, UFRGS. Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723","https://openalex.org/I4210097146"]},{"raw_affiliation_string":"Experimental Laboratory of Hepatology and Gastroenterology, Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Porto Alegre, Brazil;","institution_ids":["https://openalex.org/I4210097146"]},{"raw_affiliation_string":"Post Graduate Program in Gastroenterology and Hepatology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5037603233"],"corresponding_institution_ids":["https://openalex.org/I130442723","https://openalex.org/I4210097146"],"apc_list":null,"apc_paid":null,"fwci":2.2222,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.85677117,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"39","issue":"2","first_page":"163","last_page":"170"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.004999999888241291,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lactobacillus-rhamnosus-gg","display_name":"Lactobacillus rhamnosus GG","score":0.9549999833106995},{"id":"https://openalex.org/keywords/probiotics","display_name":"probiotics","score":0.8040000200271606},{"id":"https://openalex.org/keywords/alcoholic-liver-disease","display_name":"alcoholic liver disease","score":0.9929999709129333},{"id":"https://openalex.org/keywords/intestinal-permeability","display_name":"intestinal permeability","score":0.7250000238418579},{"id":"https://openalex.org/keywords/inflammasome","display_name":"inflammasome","score":0.7979999780654907},{"id":"https://openalex.org/keywords/hepatic-steatosis","display_name":"hepatic steatosis","score":0.8960000276565552},{"id":"https://openalex.org/keywords/gastrointestinal-colonization","display_name":"intestinal colonization","score":0.7910000085830688},{"id":"https://openalex.org/keywords/zebrafish","display_name":"zebrafish","score":0.6840000152587891},{"id":"https://openalex.org/keywords/ethanol-induced-liver-injury","display_name":"ethanol-induced liver injury","score":0.7639999985694885},{"id":"https://openalex.org/keywords/interleukin-1beta","display_name":"IL-1\u03b2","score":0.8479999899864197},{"id":"https://openalex.org/keywords/intestinal-barrier","display_name":"intestinal barrier","score":0.6039999723434448},{"id":"https://openalex.org/keywords/intestinal-inflammation","display_name":"intestinal inflammation","score":0.6209999918937683}],"concepts":[{"id":"https://openalex.org/C2776651480","wikidata":"https://www.wikidata.org/wiki/Q1607640","display_name":"Lactobacillus rhamnosus","level":4,"score":0.8689610958099365},{"id":"https://openalex.org/C2776175330","wikidata":"https://www.wikidata.org/wiki/Q1365091","display_name":"Steatosis","level":2,"score":0.7123932242393494},{"id":"https://openalex.org/C2777575235","wikidata":"https://www.wikidata.org/wiki/Q558404","display_name":"Alcoholic liver disease","level":3,"score":0.6666642427444458},{"id":"https://openalex.org/C2781071285","wikidata":"https://www.wikidata.org/wiki/Q17141320","display_name":"Intestinal permeability","level":2,"score":0.6586799621582031},{"id":"https://openalex.org/C2780255968","wikidata":"https://www.wikidata.org/wiki/Q1816730","display_name":"Probiotic","level":3,"score":0.6388465166091919},{"id":"https://openalex.org/C539455810","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut flora","level":2,"score":0.5178887844085693},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.4686906337738037},{"id":"https://openalex.org/C2780206646","wikidata":"https://www.wikidata.org/wiki/Q1061596","display_name":"Lactobacillus","level":3,"score":0.4395253360271454},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4341581165790558},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4227566719055176},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.29894328117370605},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.24775168299674988},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2463628351688385},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.17557421326637268},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.09144017100334167},{"id":"https://openalex.org/C2777214474","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Cirrhosis","level":2,"score":0.08940136432647705},{"id":"https://openalex.org/C100544194","wikidata":"https://www.wikidata.org/wiki/Q41760","display_name":"Fermentation","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069196","descriptor_name":"Gastrointestinal Microbiome","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000431","descriptor_name":"Ethanol","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005234","descriptor_name":"Fatty Liver","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008108","descriptor_name":"Liver Diseases, Alcoholic","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D010539","descriptor_name":"Permeability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D019936","descriptor_name":"Probiotics","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D050356","descriptor_name":"Lipid Metabolism","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D052201","descriptor_name":"Lacticaseibacillus rhamnosus","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D052201","descriptor_name":"Lacticaseibacillus rhamnosus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D058847","descriptor_name":"Inflammasomes","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D058847","descriptor_name":"Inflammasomes","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1080/07315724.2019.1627955","doi":"https://doi.org/10.1080/07315724.2019.1627955","is_oa":false,"landing_page_url":"https://doi.org/10.1080/07315724.2019.1627955","pdf_url":null,"source":{"id":"https://openalex.org/S102275522","display_name":"Journal of the American College of Nutrition","issn_l":"0731-5724","issn":["0731-5724","1541-1087"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Nutrition","raw_type":"journal-article"},{"id":"pmid:31241423","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31241423","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Nutrition","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W155910420","https://openalex.org/W1556198965","https://openalex.org/W1626664198","https://openalex.org/W1795353207","https://openalex.org/W1841454127","https://openalex.org/W1968465136","https://openalex.org/W1969579498","https://openalex.org/W1975752601","https://openalex.org/W1977854277","https://openalex.org/W1982573446","https://openalex.org/W2000422049","https://openalex.org/W2009514456","https://openalex.org/W2045333877","https://openalex.org/W2050116830","https://openalex.org/W2053422932","https://openalex.org/W2053661184","https://openalex.org/W2057641970","https://openalex.org/W2073168642","https://openalex.org/W2084109348","https://openalex.org/W2097823370","https://openalex.org/W2098706584","https://openalex.org/W2110235509","https://openalex.org/W2121303369","https://openalex.org/W2128190429","https://openalex.org/W2136354950","https://openalex.org/W2144171535","https://openalex.org/W2151623669","https://openalex.org/W2160652650","https://openalex.org/W2311307412","https://openalex.org/W2580767461","https://openalex.org/W2596779324","https://openalex.org/W2599741659","https://openalex.org/W2602405366","https://openalex.org/W2772186552","https://openalex.org/W2793947535","https://openalex.org/W2952275027","https://openalex.org/W3006093092","https://openalex.org/W4211110117"],"related_works":["https://openalex.org/W2938800012","https://openalex.org/W2138986581","https://openalex.org/W211451616","https://openalex.org/W2021897148","https://openalex.org/W2121303369","https://openalex.org/W2009514456","https://openalex.org/W4212774034","https://openalex.org/W4400344282","https://openalex.org/W1795353207"],"abstract_inverted_index":{"Objective:":[0],"Alcoholic":[1],"liver":[2,13],"disease":[3],"(ALD)":[4],"is":[5],"among":[6],"the":[7,16,36,67,111,130,187,190,199],"leading":[8],"causes":[9],"of":[10,30,38,48,57,72,113,129,138,144,189,195],"death":[11],"from":[12],"disease.":[14],"Among":[15],"factors":[17],"involved":[18],"in":[19,54,180],"its":[20],"pathogenesis":[21],"are":[22],"inflammation":[23],"and":[24,50,93,99,119,127,163,193],"increased":[25],"intestinal":[26,74,151],"permeability.":[27],"The":[28,142],"aim":[29],"this":[31,114],"study":[32],"was":[33,63,175],"to":[34,65,103,169],"assess":[35,66],"effect":[37],"Lactobacillus":[39],"rhamnosus":[40],"GG":[41],"(LGG)":[42],"on":[43],"hepatic":[44,157,178],"lipid":[45,158],"accumulation,":[46,159],"activation":[47],"inflammasomes,":[49],"gut":[51,139,196,200],"permeability":[52,140],"markers":[53,194],"experimental":[55],"model":[56],"ALD":[58,181],"with":[59,173],"zebrafish.Methods:":[60],"An":[61],"experiment":[62],"conducted":[64],"effective":[68],"LGG":[69,174,185],"dose":[70,143],"capable":[71],"promoting":[73],"colonization.":[75,152],"Animals":[76],"were":[77,101,117,121,134],"divided":[78],"into":[79],"three":[80],"groups":[81],"(n":[82],"=":[83],"64/group):":[84],"ethanol":[85,88,105],"group":[86,91,95,170],"(E),":[87],"+":[89],"probiotic":[90],"(EP),":[92],"control":[94],"(C).":[96],"Groups":[97],"E":[98],"EP":[100,154],"exposed":[102],"0.5%":[104],"concentration":[106],"for":[107,123,136,177],"28":[108],"days.":[109],"At":[110],"end":[112],"period,":[115],"animals":[116],"euthanized,":[118],"livers":[120],"collected":[122,135],"Oil":[124],"Red":[125],"staining":[126],"assessment":[128],"inflammasome":[131],"system.":[132],"Intestines":[133],"evaluation":[137],"markers.Results:":[141],"1.55":[145],"\u00d7":[146],"106":[147],"UFC":[148],"LGG/fish/d":[149],"promoted":[150],"Group":[153],"presented":[155],"lower":[156,160],"il-1\u03b2":[161],"expression,":[162],"higher":[164],"cldn15a":[165],"expression":[166],"when":[167],"compared":[168],"E.Conclusions:":[171],"Supplementation":[172],"protective":[176],"steatosis":[179],"model.":[182],"In":[183],"addition,":[184],"influenced":[186],"modulation":[188],"inflammatory":[191],"response":[192],"permeability,":[197],"improving":[198],"barrier":[201],"structure.":[202]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2019-07-12T00:00:00"}