{"id":"https://openalex.org/W2954712969","doi":"https://doi.org/10.1249/01.mss.0000563409.81834.ae","title":"Differences in T1\u03c1 Relaxation Time in the Vastus Lateralis after an Anterior Cruciate Ligament Tear","display_name":"Differences in T1\u03c1 Relaxation Time in the Vastus Lateralis after an Anterior Cruciate Ligament Tear","publication_year":2019,"publication_date":"2019-06-01","ids":{"openalex":"https://openalex.org/W2954712969","doi":"https://doi.org/10.1249/01.mss.0000563409.81834.ae","mag":"2954712969"},"language":"en","primary_location":{"id":"doi:10.1249/01.mss.0000563409.81834.ae","doi":"https://doi.org/10.1249/01.mss.0000563409.81834.ae","is_oa":false,"landing_page_url":"https://doi.org/10.1249/01.mss.0000563409.81834.ae","pdf_url":null,"source":{"id":"https://openalex.org/S14544163","display_name":"Medicine & Science in Sports & Exercise","issn_l":"0195-9131","issn":["0195-9131","1530-0315"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medicine &amp; Science in Sports &amp; Exercise","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009171777","display_name":"Madalyn G. Romines","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Madalyn G. Romines","raw_affiliation_strings":["University of Kentucky, Lexington, KY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Kentucky, Lexington, KY","institution_ids":["https://openalex.org/I143302722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037513860","display_name":"Lauren N. Erickson","orcid":"https://orcid.org/0000-0001-8727-6023","observed_orcids":["https://orcid.org/0000-0001-8727-6023"]},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lauren N. Erickson","raw_affiliation_strings":["University of Kentucky, Lexington, KY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Kentucky, Lexington, KY","institution_ids":["https://openalex.org/I143302722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081289484","display_name":"Kylie A. Davis","orcid":"https://orcid.org/0000-0002-5118-5979","observed_orcids":["https://orcid.org/0000-0002-5118-5979"]},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kylie A. Davis","raw_affiliation_strings":["University of Kentucky, Lexington, KY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Kentucky, Lexington, KY","institution_ids":["https://openalex.org/I143302722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030368115","display_name":"Peter Hardy","orcid":"https://orcid.org/0000-0003-0956-0138","observed_orcids":["https://orcid.org/0000-0003-0956-0138"]},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter A. Hardy","raw_affiliation_strings":["University of Kentucky, Lexington, KY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Kentucky, Lexington, KY","institution_ids":["https://openalex.org/I143302722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102797724","display_name":"Anders H. Andersen","orcid":"https://orcid.org/0000-0002-0979-8405","observed_orcids":["https://orcid.org/0000-0002-0979-8405"]},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anders H. Andersen","raw_affiliation_strings":["University of Kentucky, Lexington, KY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Kentucky, Lexington, KY","institution_ids":["https://openalex.org/I143302722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005754471","display_name":"Cale Andrew Jacobs","orcid":"https://orcid.org/0000-0002-9300-5550","observed_orcids":["https://orcid.org/0000-0002-9300-5550"]},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cale J. Jacobs","raw_affiliation_strings":["University of Kentucky, Lexington, KY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Kentucky, Lexington, KY","institution_ids":["https://openalex.org/I143302722"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048867793","display_name":"Brian W. Noehren","orcid":"https://orcid.org/0000-0001-9250-7439","observed_orcids":["https://orcid.org/0000-0001-9250-7439"]},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brian Noehren","raw_affiliation_strings":["University of Kentucky, Lexington, KY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Kentucky, Lexington, KY","institution_ids":["https://openalex.org/I143302722"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I143302722"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"51","issue":"6S","first_page":"970","last_page":"970"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10442","display_name":"Knee injuries and reconstruction techniques","score":0.7343999743461609,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10442","display_name":"Knee injuries and reconstruction techniques","score":0.7343999743461609,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.18970000743865967,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11068","display_name":"Tendon Structure and Treatment","score":0.01360000018030405,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/t1rho-relaxation-time","display_name":"T1rho relaxation time","score":0.8870000243186951},{"id":"https://openalex.org/keywords/vastus-lateralis","display_name":"vastus lateralis","score":0.9399999976158142},{"id":"https://openalex.org/keywords/anterior-cruciate-ligament-tear","display_name":"anterior cruciate ligament rupture","score":0.9449999928474426},{"id":"https://openalex.org/keywords/quadriceps-atrophy","display_name":"quadriceps atrophy","score":0.8450000286102295},{"id":"https://openalex.org/keywords/muscle-fibrosis","display_name":"muscle fibrosis","score":0.8970000147819519},{"id":"https://openalex.org/keywords/extracellular-matrix","display_name":"extracellular matrix","score":0.7739999890327454},{"id":"https://openalex.org/keywords/quadriceps-strength","display_name":"quadriceps strength","score":0.9350000023841858},{"id":"https://openalex.org/keywords/isometric-torque","display_name":"isometric torque","score":0.875},{"id":"https://openalex.org/keywords/knee-mri","display_name":"knee MRI","score":0.4309999942779541},{"id":"https://openalex.org/keywords/anterior-cruciate-ligament-deficiency","display_name":"anterior cruciate ligament deficiency","score":0.4819999933242798},{"id":"https://openalex.org/keywords/knee-laxity","display_name":"knee laxity","score":0.4059999883174896},{"id":"https://openalex.org/keywords/knee-valgus-angle","display_name":"knee valgus angle","score":0.37299999594688416},{"id":"https://openalex.org/keywords/knee-flexion-angle","display_name":"knee flexion angle","score":0.5440000295639038},{"id":"https://openalex.org/keywords/knee-extension-angle","display_name":"knee extension angle","score":0.4129999876022339}],"concepts":[{"id":"https://openalex.org/C2778434673","wikidata":"https://www.wikidata.org/wiki/Q611127","display_name":"Anterior cruciate ligament","level":2,"score":0.7840170860290527},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7140757441520691},{"id":"https://openalex.org/C2781170992","wikidata":"https://www.wikidata.org/wiki/Q18912826","display_name":"ACL injury","level":3,"score":0.5898725390434265},{"id":"https://openalex.org/C103486182","wikidata":"https://www.wikidata.org/wiki/Q1216236","display_name":"Isometric exercise","level":2,"score":0.5230385065078735},{"id":"https://openalex.org/C2780887989","wikidata":"https://www.wikidata.org/wiki/Q4771338","display_name":"Anterior cruciate ligament reconstruction","level":3,"score":0.5169703364372253},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.491896390914917},{"id":"https://openalex.org/C2780993623","wikidata":"https://www.wikidata.org/wiki/Q1590935","display_name":"Vastus medialis","level":3,"score":0.44797107577323914},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.3648202419281006},{"id":"https://openalex.org/C2777515770","wikidata":"https://www.wikidata.org/wiki/Q507369","display_name":"Electromyography","level":2,"score":0.29343318939208984},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.23240169882774353},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.19018614292144775},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.1657121181488037}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1249/01.mss.0000563409.81834.ae","doi":"https://doi.org/10.1249/01.mss.0000563409.81834.ae","is_oa":false,"landing_page_url":"https://doi.org/10.1249/01.mss.0000563409.81834.ae","pdf_url":null,"source":{"id":"https://openalex.org/S14544163","display_name":"Medicine & Science in Sports & Exercise","issn_l":"0195-9131","issn":["0195-9131","1530-0315"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medicine &amp; Science in Sports &amp; Exercise","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4294797270","https://openalex.org/W4406536526","https://openalex.org/W2904018439","https://openalex.org/W3209216123","https://openalex.org/W2346502876","https://openalex.org/W2583068418","https://openalex.org/W1984247190","https://openalex.org/W4413109377","https://openalex.org/W2954482701","https://openalex.org/W3126108406"],"abstract_inverted_index":{"Anterior":[0],"cruciate":[1],"ligament":[2],"(ACL)":[3],"injury":[4,150],"results":[5],"in":[6,12,108,112,246,274,325],"quadriceps":[7,85,98,131,335],"atrophy":[8],"and":[9,37,66,89,120,127,228,349],"fibrotic":[10,55],"changes":[11,324],"the":[13,17,84,87,106,113,118,167,170,175,238,247,252,275,280],"extracellular":[14],"matrix":[15,192],"of":[16,86,169,174,185,352],"muscle":[18,29,326,353],"that":[19,316],"may":[20],"not":[21,71,101,298,338],"resolve.":[22],"To":[23,104],"date,":[24],"assessments":[25],"have":[26],"used":[27,61,235],"a":[28,40,160,205,224,332,343],"biopsy;":[30],"however,":[31,296],"this":[32,317],"is":[33,81,100,319],"an":[34,124,155],"invasive":[35],"procedure":[36],"impractical":[38],"on":[39,223],"wide":[41],"scale.":[42],"Magnetic":[43],"resonance":[44],"imaging":[45],"(MRI)":[46],"techniques,":[47],"such":[48],"as":[49,92,94,278],"T1\u03c1,":[50],"hold":[51],"promise":[52],"to":[53,62,75,97,130,204,236,251,279,321,329,334],"measure":[54,322],"changes.":[56],"This":[57],"technique":[58],"has":[59,70],"been":[60,72],"study":[63],"cartilage":[64],"degeneration":[65],"liver":[67],"fibrosis,":[68],"but":[69],"widely":[73],"applied":[74],"muscle.":[76],"Whether":[77],"T1\u03c1":[78,109,157,241,303,308,341],"relaxation":[79,110],"time":[80,304],"different":[82,344],"between":[83,117],"injured":[88,119],"non-injured":[90,121],"limbs,":[91],"well":[93],"its":[95],"relationship":[96,333],"strength,":[99],"established.":[102],"PURPOSE:":[103],"investigate":[105],"variance":[107],"times":[111,184,242],"vastus":[114],"lateralis":[115],"(VL)":[116],"limb":[122,249,254,277,282],"following":[123],"ACL":[125,135],"tear":[126],"possible":[128],"correspondence":[129],"strength.":[132],"METHODS:":[133],"17":[134],"deficient":[136],"patients":[137],"(8M,":[138],"9F,":[139],"21":[140],"\u00b1":[141,146,152,257,262,285,290],"4.52":[142],"y,":[143],"BMI":[144],"25.95":[145],"3.83,":[147],"days":[148],"since":[149],"26":[151],"17.26)":[153],"underwent":[154],"MRI.":[156],"acquisition":[158],"included":[159],"single":[161],"6":[162],"mm":[163],"thick":[164],"slice":[165],"at":[166],"location":[168],"largest":[171],"cross-sectional":[172],"area":[173],"VL":[176],"with":[177,196,301],"8":[178],"echoes":[179],"collected":[180],"within":[181],"spin":[182],"lock":[183,189],"0-70":[186],"ms":[187],"(spin":[188],"amplitude":[190],"300Hz,":[191],"256x256,":[193],"2":[194],"excitations":[195],"4":[197],"shots":[198],"per":[199],"slice).":[200],"Data":[201],"was":[202,216,271,297,309,337],"fitted":[203],"mono":[206],"exponential":[207],"decay":[208],"curve":[209],"using":[210],"custom":[211],"MATLAB":[212],"code.":[213],"Quadriceps":[214],"strength":[215,336,348],"assessed":[217],"via":[218],"maximal":[219],"voluntary":[220],"isometric":[221,269],"contractions":[222],"dynamometer.":[225],"Paired":[226],"t-tests":[227],"Pearson":[229],"product":[230],"moment":[231],"correlation":[232],"coefficients":[233],"were":[234,243],"analyze":[237],"data.":[239],"RESULTS:":[240],"significantly":[244,272,299,310],"longer":[245,302,311],"involved":[248,276],"compared":[250],"non-involved":[253,281],"(involved:":[255,283],"0.0296":[256],"0.0032":[258],"s;":[259,264],"non-involved:":[260,288],"0.0280":[261],"0.0031":[263],"5.7%":[265],"difference;":[266,294],"p=0.04).":[267],"Peak":[268],"torque":[270],"less":[273],"1.91":[284],"0.71":[286],"Nm/kg;":[287,292],"2.65":[289],"0.52":[291],"27.7%":[293],"p<0.001);":[295],"correlated":[300],"(r=0.07;":[305],"p=0.70).":[306],"CONCLUSION:":[307],"soon":[312],"after":[313],"injury,":[314],"indicating":[315],"tool":[318],"sensitive":[320],"early":[323],"organization.":[327],"Contrary":[328],"our":[330],"hypothesis,":[331],"found.":[339],"Potentially,":[340],"measures":[342],"factor":[345],"than":[346],"peak":[347],"additional":[350],"variables":[351],"function":[354],"should":[355],"be":[356],"evaluated.":[357],"NIH":[358],"R01AR071398":[359]},"counts_by_year":[],"updated_date":"2026-10-17T09:40:24.721904","created_date":"2019-07-12T00:00:00"}