{"id":"https://openalex.org/W2954700534","doi":"https://doi.org/10.6026/97320630015172","title":"Effect of salvia Officinalis L. and Rosmarinus Officinalis L. leaves extracts on anxiety and neural activity","display_name":"Effect of salvia Officinalis L. and Rosmarinus Officinalis L. leaves extracts on anxiety and neural activity","publication_year":2019,"publication_date":"2019-03-15","ids":{"openalex":"https://openalex.org/W2954700534","doi":"https://doi.org/10.6026/97320630015172","mag":"2954700534","pmid":"https://pubmed.ncbi.nlm.nih.gov/31354192","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6637401"},"language":"en","primary_location":{"id":"doi:10.6026/97320630015172","doi":"https://doi.org/10.6026/97320630015172","is_oa":true,"landing_page_url":"https://doi.org/10.6026/97320630015172","pdf_url":"http://www.bioinformation.net/015/97320630015172.pdf","source":{"id":"https://openalex.org/S2755911950","display_name":"Bioinformation","issn_l":"0973-2063","issn":["0973-2063","0973-8894"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","ki-jl-1","norway-1","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4328143488","host_organization_name":"Biomedical Informatics","host_organization_lineage":["https://openalex.org/P4328143488"],"host_organization_lineage_names":["Biomedical Informatics"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://www.bioinformation.net/015/97320630015172.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055719108","display_name":"Zineb Choukairi","orcid":"https://orcid.org/0000-0002-2490-5029","observed_orcids":["https://orcid.org/0000-0002-2490-5029"]},"institutions":[{"id":"https://openalex.org/I4210164065","display_name":"Universit\u00e9 Hassan II Mohammedia","ror":"https://ror.org/058gnfy87","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210164065"]},{"id":"https://openalex.org/I99297268","display_name":"University of Hassan II Casablanca","ror":"https://ror.org/001q4kn48","country_code":"MA","type":"education","lineage":["https://openalex.org/I99297268"]}],"countries":["MA"],"is_corresponding":true,"raw_author_name":"Zineb Choukairi","raw_affiliation_strings":["Laboratory of Biosciences, Functional, integrated and molecular exploration, School Of Sciences and Technology - Mohammedia, Hassan II University of Casablanca"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biosciences, Functional, integrated and molecular exploration, School Of Sciences and Technology - Mohammedia, Hassan II University of Casablanca","institution_ids":["https://openalex.org/I4210164065","https://openalex.org/I99297268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081744631","display_name":"Tahar Hazzaz Abouamal","orcid":"https://orcid.org/0009-0001-3108-2710","observed_orcids":["https://orcid.org/0009-0001-3108-2710"]},"institutions":[{"id":"https://openalex.org/I4210164065","display_name":"Universit\u00e9 Hassan II Mohammedia","ror":"https://ror.org/058gnfy87","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210164065"]},{"id":"https://openalex.org/I99297268","display_name":"University of Hassan II Casablanca","ror":"https://ror.org/001q4kn48","country_code":"MA","type":"education","lineage":["https://openalex.org/I99297268"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Tahar Hazzaz","raw_affiliation_strings":["Laboratory of Biosciences, Functional, integrated and molecular exploration, School Of Sciences and Technology - Mohammedia, Hassan II University of Casablanca"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biosciences, Functional, integrated and molecular exploration, School Of Sciences and Technology - Mohammedia, Hassan II University of Casablanca","institution_ids":["https://openalex.org/I4210164065","https://openalex.org/I99297268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024607354","display_name":"Mustapha Lkhider","orcid":"https://orcid.org/0000-0002-4886-601X","observed_orcids":["https://orcid.org/0000-0002-4886-601X"]},"institutions":[{"id":"https://openalex.org/I4210164065","display_name":"Universit\u00e9 Hassan II Mohammedia","ror":"https://ror.org/058gnfy87","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210164065"]},{"id":"https://openalex.org/I99297268","display_name":"University of Hassan II Casablanca","ror":"https://ror.org/001q4kn48","country_code":"MA","type":"education","lineage":["https://openalex.org/I99297268"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Mustapha Lkhider","raw_affiliation_strings":["Laboratory of Biosciences, Functional, integrated and molecular exploration, School Of Sciences and Technology - Mohammedia, Hassan II University of Casablanca"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biosciences, Functional, integrated and molecular exploration, School Of Sciences and Technology - Mohammedia, Hassan II University of Casablanca","institution_ids":["https://openalex.org/I4210164065","https://openalex.org/I99297268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009983639","display_name":"Jos\u00e9 Manuel Ferr\u00e1ndez Vicente","orcid":"https://orcid.org/0000-0002-4613-6101","observed_orcids":["https://orcid.org/0000-0002-4613-6101"]},"institutions":[{"id":"https://openalex.org/I3123212020","display_name":"Universidad Polit\u00e9cnica de Cartagena","ror":"https://ror.org/02k5kx966","country_code":"ES","type":"education","lineage":["https://openalex.org/I3123212020"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Manuel Ferrandez","raw_affiliation_strings":["Laboratory Of \"Inteligencia Ambiental\", Polytechnic University of Cartagena, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory Of \"Inteligencia Ambiental\", Polytechnic University of Cartagena, Spain","institution_ids":["https://openalex.org/I3123212020"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112378818","display_name":"Taoufiq Fechtali","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210164065","display_name":"Universit\u00e9 Hassan II Mohammedia","ror":"https://ror.org/058gnfy87","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210164065"]},{"id":"https://openalex.org/I99297268","display_name":"University of Hassan II Casablanca","ror":"https://ror.org/001q4kn48","country_code":"MA","type":"education","lineage":["https://openalex.org/I99297268"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Taoufiq Fechtali","raw_affiliation_strings":["Laboratory of Biosciences, Functional, integrated and molecular exploration, School Of Sciences and Technology - Mohammedia, Hassan II University of Casablanca"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biosciences, Functional, integrated and molecular exploration, School Of Sciences and Technology - Mohammedia, Hassan II University of Casablanca","institution_ids":["https://openalex.org/I4210164065","https://openalex.org/I99297268"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5055719108"],"corresponding_institution_ids":["https://openalex.org/I4210164065","https://openalex.org/I99297268"],"apc_list":null,"apc_paid":null,"fwci":2.3256,"has_fulltext":true,"cited_by_count":16,"citation_normalized_percentile":{"value":0.8593609,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"15","issue":"3","first_page":"172","last_page":"178"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13090","display_name":"Medicinal Plant Extracts Effects","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13090","display_name":"Medicinal Plant Extracts Effects","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13651","display_name":"Medicinal Plants and Bioactive Compounds","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12891","display_name":"Medicinal Plants and Neuroprotection","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/salvia-officinalis","display_name":"Salvia officinalis","score":0.9710000157356262},{"id":"https://openalex.org/keywords/rosemary","display_name":"Rosmarinus officinalis","score":0.9900000095367432},{"id":"https://openalex.org/keywords/leaf-extract","display_name":"leaf extract","score":0.6359999775886536},{"id":"https://openalex.org/keywords/anxiety","display_name":"anxiety","score":0.9729999899864197},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.5479999780654907},{"id":"https://openalex.org/keywords/neuronal-activity","display_name":"neuronal activity","score":0.8080000281333923},{"id":"https://openalex.org/keywords/microelectrode-arrays","display_name":"microelectrode arrays","score":0.8349999785423279},{"id":"https://openalex.org/keywords/open-field-test","display_name":"open field test","score":0.7310000061988831},{"id":"https://openalex.org/keywords/marble-burying-test","display_name":"marble burying test","score":0.9789999723434448},{"id":"https://openalex.org/keywords/immobility-time","display_name":"immobility time","score":0.8349999785423279}],"concepts":[{"id":"https://openalex.org/C2777152263","wikidata":"https://www.wikidata.org/wiki/Q1865680","display_name":"Rosmarinus","level":3,"score":0.9366494417190552},{"id":"https://openalex.org/C2780886089","wikidata":"https://www.wikidata.org/wiki/Q7079617","display_name":"Officinalis","level":2,"score":0.9117969870567322},{"id":"https://openalex.org/C2779085643","wikidata":"https://www.wikidata.org/wiki/Q7096029","display_name":"Open field","level":2,"score":0.6293798089027405},{"id":"https://openalex.org/C2911011617","wikidata":"https://www.wikidata.org/wiki/Q1111359","display_name":"Salvia officinalis","level":3,"score":0.6016225814819336},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.5843193531036377},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.5248717665672302},{"id":"https://openalex.org/C173586616","wikidata":"https://www.wikidata.org/wiki/Q5359685","display_name":"Elevated plus maze","level":3,"score":0.5211803317070007},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5186354517936707},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.22306913137435913}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.6026/97320630015172","doi":"https://doi.org/10.6026/97320630015172","is_oa":true,"landing_page_url":"https://doi.org/10.6026/97320630015172","pdf_url":"http://www.bioinformation.net/015/97320630015172.pdf","source":{"id":"https://openalex.org/S2755911950","display_name":"Bioinformation","issn_l":"0973-2063","issn":["0973-2063","0973-8894"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","ki-jl-1","norway-1","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4328143488","host_organization_name":"Biomedical Informatics","host_organization_lineage":["https://openalex.org/P4328143488"],"host_organization_lineage_names":["Biomedical Informatics"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformation","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6637401","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6637401","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformation","raw_type":"Text"},{"id":"pmid:31354192","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31354192","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformation","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.6026/97320630015172","doi":"https://doi.org/10.6026/97320630015172","is_oa":true,"landing_page_url":"https://doi.org/10.6026/97320630015172","pdf_url":"http://www.bioinformation.net/015/97320630015172.pdf","source":{"id":"https://openalex.org/S2755911950","display_name":"Bioinformation","issn_l":"0973-2063","issn":["0973-2063","0973-8894"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","ki-jl-1","norway-1","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4328143488","host_organization_name":"Biomedical Informatics","host_organization_lineage":["https://openalex.org/P4328143488"],"host_organization_lineage_names":["Biomedical Informatics"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformation","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320335551","display_name":"Erasmus+","ror":"https://ror.org/01v2m4n16"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2954700534.pdf","grobid_xml":"https://content.openalex.org/works/W2954700534.grobid-xml"},"referenced_works_count":21,"referenced_works":["https://openalex.org/W1809436058","https://openalex.org/W1947883362","https://openalex.org/W1966037459","https://openalex.org/W1984601608","https://openalex.org/W1988846707","https://openalex.org/W1989978179","https://openalex.org/W2009646296","https://openalex.org/W2028756415","https://openalex.org/W2030264101","https://openalex.org/W2040435198","https://openalex.org/W2047163176","https://openalex.org/W2063395206","https://openalex.org/W2082617646","https://openalex.org/W2090681969","https://openalex.org/W2096972451","https://openalex.org/W2097213447","https://openalex.org/W2140107414","https://openalex.org/W2144626458","https://openalex.org/W2738330305","https://openalex.org/W4246350751","https://openalex.org/W4252846393"],"related_works":["https://openalex.org/W2334542880","https://openalex.org/W2256442006","https://openalex.org/W7167215555","https://openalex.org/W2472850968","https://openalex.org/W3011747366","https://openalex.org/W4286472381","https://openalex.org/W4391600927","https://openalex.org/W2182000369","https://openalex.org/W2905860615","https://openalex.org/W2884137792"],"abstract_inverted_index":{"Anxiety,":[0],"the":[1,9,49,73,79,82,85,93,97,100,105,110,121,125,129,138,146,156,162,167,176,181],"illness":[2],"of":[3,8,29,45,52,81,84,99,114,137,145,148,158,161,178,180],"our":[4],"time,":[5],"is":[6,24,34,44],"one":[7],"most":[10],"prevalent":[11],"and":[12,32,56,68,152],"co-morbid":[13],"psychiatric":[14],"disorder":[15],"that":[16],"represents":[17],"a":[18,27,35,89,135,143],"significant":[19,90],"socioeconomic":[20],"burden.":[21],"Conventional":[22],"treatment":[23],"associated":[25,87],"with":[26,88],"number":[28,113,147],"side":[30],"effects":[31,51],"there":[33,171],"need":[36],"to":[37,47,109,166],"develop":[38],"new":[39],"therapeutic":[40],"strategies.":[41],"Therefore,":[42],"it":[43],"interest":[46],"investigate":[48],"modulating":[50],"Salvia":[53],"Officinalis":[54,58],"L.":[55,59],"Rosmarinus":[57],"leaves":[60],"extracts":[61,165],"on":[62,69],"anxiety":[63],"using":[64,72],"different":[65],"behavioral":[66],"tests,":[67],"neural":[70,139,168],"activity":[71,140],"Multi-electrode":[74],"array":[75],"technique.":[76],"Data":[77],"shows":[78],"decrease":[80,136,144],"time":[83,94],"immobility":[86],"increase":[91],"in":[92,96,104,120,124],"spent":[95],"center":[98],"open":[101],"field":[102],"arena":[103],"treated":[106,122],"animals":[107,123],"compared":[108],"controls.":[111],"The":[112],"buried":[115],"marbles":[116],"has":[117],"also":[118,133],"decreased":[119],"marble-burying":[126],"test.":[127],"On":[128],"other":[130],"hand":[131],"results":[132],"show":[134],"explained":[141],"by":[142],"spikes":[149,174],"after":[150,175],"24,48":[151],"72":[153],"h":[154],"following":[155],"addition":[157],"12,5":[159],"\u00b5g/ml":[160],"plant":[163],"leaf":[164],"culture.":[169],"However,":[170],"were":[172],"no":[173],"administration":[177],"25\u00b5g/ml":[179],"plants":[182],"extracts.":[183]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-07-12T00:00:00"}