{"id":"https://openalex.org/W2953908751","doi":"https://doi.org/10.5713/ajas.19.0173","title":"MiR-26a promotes apoptosis of porcine granulosa cells by targeting the 3\u03b2-hydroxysteroid-\u039424-reductase gene","display_name":"MiR-26a promotes apoptosis of porcine granulosa cells by targeting the 3\u03b2-hydroxysteroid-\u039424-reductase gene","publication_year":2019,"publication_date":"2019-07-01","ids":{"openalex":"https://openalex.org/W2953908751","doi":"https://doi.org/10.5713/ajas.19.0173","mag":"2953908751","pmid":"https://pubmed.ncbi.nlm.nih.gov/31480202","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7054607"},"language":"en","primary_location":{"id":"doi:10.5713/ajas.19.0173","doi":"https://doi.org/10.5713/ajas.19.0173","is_oa":true,"landing_page_url":"https://doi.org/10.5713/ajas.19.0173","pdf_url":"https://www.animbiosci.org/upload/pdf/ajas-19-0173.pdf","source":{"id":"https://openalex.org/S118716465","display_name":"Asian-Australasian Journal of Animal Sciences","issn_l":"1011-2367","issn":["1011-2367","1976-5517"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310319462","host_organization_name":"Asian-Australasian Association of Animal Production Societies","host_organization_lineage":["https://openalex.org/P4310319462"],"host_organization_lineage_names":["Asian-Australasian Association of Animal Production Societies"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Asian-Australasian Journal of Animal Sciences","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2953908751"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.animbiosci.org/upload/pdf/ajas-19-0173.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100376244","display_name":"Xiaodong Zhang","orcid":"https://orcid.org/0000-0003-4677-1620","observed_orcids":["https://orcid.org/0000-0003-4677-1620"]},"institutions":[{"id":"https://openalex.org/I140221134","display_name":"Anhui Agricultural University","ror":"https://ror.org/0327f3359","country_code":"CN","type":"education","lineage":["https://openalex.org/I140221134"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaodong Zhang","raw_affiliation_strings":["College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China","Key Laboratory of Local Animal Genetic Resources Conservation and Bio-Breeding of Anhui Province, Hefei, 230036, China"],"raw_orcid":"https://orcid.org/0000-0003-4677-1620","affiliations":[{"raw_affiliation_string":"College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China","institution_ids":["https://openalex.org/I140221134"]},{"raw_affiliation_string":"Key Laboratory of Local Animal Genetic Resources Conservation and Bio-Breeding of Anhui Province, Hefei, 230036, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027679279","display_name":"Qiangqiang Tao","orcid":"https://orcid.org/0000-0002-0177-8944","observed_orcids":["https://orcid.org/0000-0002-0177-8944"]},"institutions":[{"id":"https://openalex.org/I140221134","display_name":"Anhui Agricultural University","ror":"https://ror.org/0327f3359","country_code":"CN","type":"education","lineage":["https://openalex.org/I140221134"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qiangqiang Tao","raw_affiliation_strings":["College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China","Key Laboratory of Local Animal Genetic Resources Conservation and Bio-Breeding of Anhui Province, Hefei, 230036, China"],"raw_orcid":"https://orcid.org/0000-0002-0177-8944","affiliations":[{"raw_affiliation_string":"College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China","institution_ids":["https://openalex.org/I140221134"]},{"raw_affiliation_string":"Key Laboratory of Local Animal Genetic Resources Conservation and Bio-Breeding of Anhui Province, Hefei, 230036, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061585630","display_name":"Jinnan Shang","orcid":"https://orcid.org/0000-0001-5957-5413","observed_orcids":["https://orcid.org/0000-0001-5957-5413"]},"institutions":[{"id":"https://openalex.org/I140221134","display_name":"Anhui Agricultural University","ror":"https://ror.org/0327f3359","country_code":"CN","type":"education","lineage":["https://openalex.org/I140221134"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jinnan Shang","raw_affiliation_strings":["College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China","Key Laboratory of Local Animal Genetic Resources Conservation and Bio-Breeding of Anhui Province, Hefei, 230036, China"],"raw_orcid":"https://orcid.org/0000-0001-5957-5413","affiliations":[{"raw_affiliation_string":"College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China","institution_ids":["https://openalex.org/I140221134"]},{"raw_affiliation_string":"Key Laboratory of Local Animal Genetic Resources Conservation and Bio-Breeding of Anhui Province, Hefei, 230036, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yiliang Xu","orcid":"https://orcid.org/0000-0002-7714-0760","observed_orcids":["https://orcid.org/0000-0002-7714-0760"]},"institutions":[{"id":"https://openalex.org/I140221134","display_name":"Anhui Agricultural University","ror":"https://ror.org/0327f3359","country_code":"CN","type":"education","lineage":["https://openalex.org/I140221134"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yiliang Xu","raw_affiliation_strings":["College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China","Key Laboratory of Local Animal Genetic Resources Conservation and Bio-Breeding of Anhui Province, Hefei, 230036, China"],"raw_orcid":"https://orcid.org/0000-0002-7714-0760","affiliations":[{"raw_affiliation_string":"College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China","institution_ids":["https://openalex.org/I140221134"]},{"raw_affiliation_string":"Key Laboratory of Local Animal Genetic Resources Conservation and Bio-Breeding of Anhui Province, Hefei, 230036, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Liang Zhang","orcid":"https://orcid.org/0000-0003-1167-7191","observed_orcids":["https://orcid.org/0000-0003-1167-7191"]},"institutions":[{"id":"https://openalex.org/I140221134","display_name":"Anhui Agricultural University","ror":"https://ror.org/0327f3359","country_code":"CN","type":"education","lineage":["https://openalex.org/I140221134"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liang Zhang","raw_affiliation_strings":["College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China","Key Laboratory of Local Animal Genetic Resources Conservation and Bio-Breeding of Anhui Province, Hefei, 230036, China"],"raw_orcid":"https://orcid.org/0000-0003-1167-7191","affiliations":[{"raw_affiliation_string":"College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China","institution_ids":["https://openalex.org/I140221134"]},{"raw_affiliation_string":"Key Laboratory of Local Animal Genetic Resources Conservation and Bio-Breeding of Anhui Province, Hefei, 230036, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039877857","display_name":"Yingchun Ma","orcid":"https://orcid.org/0000-0002-1290-4790","observed_orcids":["https://orcid.org/0000-0002-1290-4790"]},"institutions":[{"id":"https://openalex.org/I140221134","display_name":"Anhui Agricultural University","ror":"https://ror.org/0327f3359","country_code":"CN","type":"education","lineage":["https://openalex.org/I140221134"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yingchun Ma","raw_affiliation_strings":["College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China","Key Laboratory of Local Animal Genetic Resources Conservation and Bio-Breeding of Anhui Province, Hefei, 230036, China"],"raw_orcid":"https://orcid.org/0000-0002-1290-4790","affiliations":[{"raw_affiliation_string":"College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China","institution_ids":["https://openalex.org/I140221134"]},{"raw_affiliation_string":"Key Laboratory of Local Animal Genetic Resources Conservation and Bio-Breeding of Anhui Province, Hefei, 230036, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101695993","display_name":"Weihua Zhu","orcid":"https://orcid.org/0000-0001-8740-3651","observed_orcids":["https://orcid.org/0000-0001-8740-3651"]},"institutions":[{"id":"https://openalex.org/I140221134","display_name":"Anhui Agricultural University","ror":"https://ror.org/0327f3359","country_code":"CN","type":"education","lineage":["https://openalex.org/I140221134"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weihua Zhu","raw_affiliation_strings":["College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China","Key Laboratory of Local Animal Genetic Resources Conservation and Bio-Breeding of Anhui Province, Hefei, 230036, China"],"raw_orcid":"https://orcid.org/0000-0001-8740-3651","affiliations":[{"raw_affiliation_string":"College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China","institution_ids":["https://openalex.org/I140221134"]},{"raw_affiliation_string":"Key Laboratory of Local Animal Genetic Resources Conservation and Bio-Breeding of Anhui Province, Hefei, 230036, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040143438","display_name":"Min Yang","orcid":"https://orcid.org/0000-0003-3350-0530","observed_orcids":["https://orcid.org/0000-0003-3350-0530"]},"institutions":[{"id":"https://openalex.org/I140221134","display_name":"Anhui Agricultural University","ror":"https://ror.org/0327f3359","country_code":"CN","type":"education","lineage":["https://openalex.org/I140221134"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Min Yang","raw_affiliation_strings":["College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China","Key Laboratory of Local Animal Genetic Resources Conservation and Bio-Breeding of Anhui Province, Hefei, 230036, China"],"raw_orcid":"https://orcid.org/0000-0003-3350-0530","affiliations":[{"raw_affiliation_string":"College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China","institution_ids":["https://openalex.org/I140221134"]},{"raw_affiliation_string":"Key Laboratory of Local Animal Genetic Resources Conservation and Bio-Breeding of Anhui Province, Hefei, 230036, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061945551","display_name":"Yueyun Ding","orcid":"https://orcid.org/0000-0001-7559-0736","observed_orcids":["https://orcid.org/0000-0001-7559-0736"]},"institutions":[{"id":"https://openalex.org/I140221134","display_name":"Anhui Agricultural University","ror":"https://ror.org/0327f3359","country_code":"CN","type":"education","lineage":["https://openalex.org/I140221134"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yueyun Ding","raw_affiliation_strings":["College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China","Key Laboratory of Local Animal Genetic Resources Conservation and Bio-Breeding of Anhui Province, Hefei, 230036, China"],"raw_orcid":"https://orcid.org/0000-0001-7559-0736","affiliations":[{"raw_affiliation_string":"College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China","institution_ids":["https://openalex.org/I140221134"]},{"raw_affiliation_string":"Key Laboratory of Local Animal Genetic Resources Conservation and Bio-Breeding of Anhui Province, Hefei, 230036, China","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100710227","display_name":"Zongjun Yin","orcid":"https://orcid.org/0000-0001-9893-743X","observed_orcids":["https://orcid.org/0000-0001-9893-743X","https://orcid.org/0000-0001-9912-2769"]},"institutions":[{"id":"https://openalex.org/I140221134","display_name":"Anhui Agricultural University","ror":"https://ror.org/0327f3359","country_code":"CN","type":"education","lineage":["https://openalex.org/I140221134"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zongjun Yin","raw_affiliation_strings":["College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China","Key Laboratory of Local Animal Genetic Resources Conservation and Bio-Breeding of Anhui Province, Hefei, 230036, China"],"raw_orcid":"https://orcid.org/0000-0001-9893-743X","affiliations":[{"raw_affiliation_string":"College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China","institution_ids":["https://openalex.org/I140221134"]},{"raw_affiliation_string":"Key Laboratory of Local Animal Genetic Resources Conservation and Bio-Breeding of Anhui Province, Hefei, 230036, China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5100710227"],"corresponding_institution_ids":["https://openalex.org/I140221134"],"apc_list":{"value":370,"currency":"USD","value_usd":370},"apc_paid":{"value":370,"currency":"USD","value_usd":370},"fwci":1.1623,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.74996163,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"33","issue":"4","first_page":"547","last_page":"555"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10584","display_name":"Reproductive Physiology in Livestock","score":0.9121000170707703,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10584","display_name":"Reproductive Physiology in Livestock","score":0.9121000170707703,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.050599999725818634,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.029500000178813934,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mir-26a","display_name":"miR-26a","score":0.9980000257492065},{"id":"https://openalex.org/keywords/dhcr24","display_name":"DHCR24","score":0.9480000138282776},{"id":"https://openalex.org/keywords/porcine-granulosa-cells","display_name":"porcine granulosa cells","score":0.9190000295639038},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9399999976158142},{"id":"https://openalex.org/keywords/estradiol-secretion","display_name":"estradiol secretion","score":0.8029999732971191},{"id":"https://openalex.org/keywords/progesterone-synthesis","display_name":"progesterone secretion","score":1.0},{"id":"https://openalex.org/keywords/caspase-3","display_name":"caspase-3","score":0.8220000267028809},{"id":"https://openalex.org/keywords/bcl-2","display_name":"Bcl-2","score":0.9980000257492065},{"id":"https://openalex.org/keywords/3-utr-binding","display_name":"3' UTR binding","score":0.7570000290870667},{"id":"https://openalex.org/keywords/microrna-target-regulation","display_name":"microRNA target regulation","score":0.6359999775886536},{"id":"https://openalex.org/keywords/follicular-development","display_name":"folliculogenesis","score":0.7590000033378601}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7715568542480469},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.6163873076438904},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.574070930480957},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5665099620819092},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.5371096730232239},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.4897136986255646},{"id":"https://openalex.org/C54009773","wikidata":"https://www.wikidata.org/wiki/Q1429031","display_name":"Transfection","level":3,"score":0.4758305847644806},{"id":"https://openalex.org/C89604277","wikidata":"https://www.wikidata.org/wiki/Q424345","display_name":"Untranslated region","level":4,"score":0.4538031220436096},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.44933080673217773},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.41271230578422546},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3485877513885498},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3406105041503906},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.25295811891555786},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10467246174812317}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.5713/ajas.19.0173","doi":"https://doi.org/10.5713/ajas.19.0173","is_oa":true,"landing_page_url":"https://doi.org/10.5713/ajas.19.0173","pdf_url":"https://www.animbiosci.org/upload/pdf/ajas-19-0173.pdf","source":{"id":"https://openalex.org/S118716465","display_name":"Asian-Australasian Journal of Animal Sciences","issn_l":"1011-2367","issn":["1011-2367","1976-5517"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310319462","host_organization_name":"Asian-Australasian Association of Animal Production Societies","host_organization_lineage":["https://openalex.org/P4310319462"],"host_organization_lineage_names":["Asian-Australasian Association of Animal Production Societies"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Asian-Australasian Journal of Animal Sciences","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:6061294","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7054607","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:31480202","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31480202","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Asian-Australasian journal of animal sciences","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7054607","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7054607/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Asian-Australas J Anim Sci","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:286c1498a18449628fda6799d3091c27","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/286c1498a18449628fda6799d3091c27","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Asian-Australasian Journal of Animal Sciences, Vol 33, Iss 4, Pp 547-555 (2020)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.5713/ajas.19.0173","doi":"https://doi.org/10.5713/ajas.19.0173","is_oa":true,"landing_page_url":"https://doi.org/10.5713/ajas.19.0173","pdf_url":"https://www.animbiosci.org/upload/pdf/ajas-19-0173.pdf","source":{"id":"https://openalex.org/S118716465","display_name":"Asian-Australasian Journal of Animal Sciences","issn_l":"1011-2367","issn":["1011-2367","1976-5517"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310319462","host_organization_name":"Asian-Australasian Association of Animal Production Societies","host_organization_lineage":["https://openalex.org/P4310319462"],"host_organization_lineage_names":["Asian-Australasian Association of Animal Production Societies"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Asian-Australasian Journal of Animal Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8199999928474426,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3834721266","display_name":null,"funder_award_id":"2017YFD0600805","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G6693829498","display_name":null,"funder_award_id":"31402037","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8511575564","display_name":null,"funder_award_id":"31972531","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320323887","display_name":"Anhui Agricultural University","ror":"https://ror.org/0327f3359"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2953908751.pdf","grobid_xml":"https://content.openalex.org/works/W2953908751.grobid-xml"},"referenced_works_count":38,"referenced_works":["https://openalex.org/W962052387","https://openalex.org/W1974210533","https://openalex.org/W1981626694","https://openalex.org/W1986326597","https://openalex.org/W1988449005","https://openalex.org/W1993672765","https://openalex.org/W2010507392","https://openalex.org/W2014630029","https://openalex.org/W2027860637","https://openalex.org/W2029831965","https://openalex.org/W2059117644","https://openalex.org/W2066211817","https://openalex.org/W2078442918","https://openalex.org/W2094248542","https://openalex.org/W2095750495","https://openalex.org/W2106637741","https://openalex.org/W2111269403","https://openalex.org/W2117082199","https://openalex.org/W2125093810","https://openalex.org/W2125717115","https://openalex.org/W2144285107","https://openalex.org/W2158811981","https://openalex.org/W2173456767","https://openalex.org/W2178316435","https://openalex.org/W2267171780","https://openalex.org/W2279085311","https://openalex.org/W2289310757","https://openalex.org/W2478977923","https://openalex.org/W2587852327","https://openalex.org/W2767548441","https://openalex.org/W2789174596","https://openalex.org/W2792640933","https://openalex.org/W2795291803","https://openalex.org/W2804333522","https://openalex.org/W2883165899","https://openalex.org/W2897399577","https://openalex.org/W2959144666","https://openalex.org/W2980665364"],"related_works":["https://openalex.org/W3165043171","https://openalex.org/W4365517453","https://openalex.org/W2936691068","https://openalex.org/W2754779639","https://openalex.org/W2120509278","https://openalex.org/W2279085311","https://openalex.org/W4389338862","https://openalex.org/W3035938571","https://openalex.org/W2970764472","https://openalex.org/W4416411795"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Apoptosis":[1],"of":[2,44,51,71,82,147,161,188,195,225],"ovarian":[3],"granulosa":[4],"cells":[5,34],"(GCs)":[6],"affects":[7],"mammalian":[8],"follicular":[9,32],"development":[10,43],"and":[11,24,36,63,85,109,118,128,139,151,154,175,178,200,215,218],"fecundity.":[12],"This":[13,206],"study":[14,207],"aimed":[15],"to":[16,37,46,102,123],"explore":[17],"the":[18,25,42,48,76,104,125,165,169,185,223],"regulatory":[19],"relationship":[20],"between":[21,107],"microRNA-26a":[22],"(miR-26a)":[23],"3\u03b2-hydroxysteroid-\u039424-reductase":[26],"gene":[27,29],"(DHCR24)":[28],"in":[30,65,88,131,157,181,203,227],"porcine":[31],"granular":[33],"(pGCs),":[35],"provide":[38],"empirical":[39],"data":[40],"for":[41],"methods":[45],"improve":[47],"reproductive":[49],"capacity":[50],"pigs.":[52],"METHODS:":[53],"The":[54,67,79],"pGCs":[55,72,89,173],"were":[56,90,121,184],"transfected":[57],"with":[58,136],"miR-26a":[59,61,108,137,140,148,189,196,210],"mimic,":[60],"inhibitor":[62],"DHCR24-siRNA":[64],"vitro.":[66],"cell":[68,213],"apoptosis":[69,214],"rate":[70],"was":[73,100],"detected":[74,91],"by":[75,92,221],"flow":[77],"cytometry.":[78],"secretion":[80,156,180,220],"levels":[81],"estradiol":[83],"(E2)":[84],"progesterone":[86],"(P)":[87],"enzymelinked":[93],"immunosorbent":[94],"assay.":[95],"Double":[96],"luciferase":[97],"validation":[98],"system":[99],"used":[101,122],"detect":[103],"binding":[105,186],"sites":[106,187],"DHCR24":[110,126,162,192,198,226],"3'-UTR":[111],"region.":[112],"Qualitative":[113],"real-time":[114],"polymerase":[115],"chain":[116],"reaction":[117],"Western":[119],"blotting":[120],"verify":[124],"mRNA":[127,199],"protein":[129,201],"expression":[130,202,224],"pGCs,":[132],"respectively,":[133],"after":[134],"transfecting":[135],"mimic":[138],"inhibitor.":[141],"RESULTS:":[142],"Results":[143],"showed":[144],"that":[145,209],"enhancement":[146],"promoted":[149,172],"apoptosis,":[150,174],"inhibited":[152,176,197],"E2":[153,177,217],"P":[155,179,219],"pGCs.":[158,182,204,228],"Meanwhile,":[159],"inhibition":[160],"also":[163],"upregulated":[164],"Caspase-3":[166],"expression,":[167,171],"reduced":[168],"BCL-2":[170],"There":[183],"located":[190],"within":[191],"3'-UTR.":[193],"Up-regulation":[194],"CONCLUSION:":[205],"demonstrates":[208],"can":[211],"promote":[212],"inhibit":[216],"inhibiting":[222]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2019-07-12T00:00:00"}