{"id":"https://openalex.org/W2953445487","doi":"https://doi.org/10.1016/j.freeradbiomed.2019.07.006","title":"Plin5 deficiency exacerbates pressure overload-induced cardiac hypertrophy and heart failure by enhancing myocardial fatty acid oxidation and oxidative stress","display_name":"Plin5 deficiency exacerbates pressure overload-induced cardiac hypertrophy and heart failure by enhancing myocardial fatty acid oxidation and oxidative stress","publication_year":2019,"publication_date":"2019-07-07","ids":{"openalex":"https://openalex.org/W2953445487","doi":"https://doi.org/10.1016/j.freeradbiomed.2019.07.006","mag":"2953445487","pmid":"https://pubmed.ncbi.nlm.nih.gov/31291602"},"language":"en","primary_location":{"id":"doi:10.1016/j.freeradbiomed.2019.07.006","doi":"https://doi.org/10.1016/j.freeradbiomed.2019.07.006","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.freeradbiomed.2019.07.006","pdf_url":null,"source":{"id":"https://openalex.org/S128018148","display_name":"Free Radical Biology and Medicine","issn_l":"0891-5849","issn":["0891-5849","1873-4596"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Free Radical Biology and Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100407178","display_name":"Chao Wang","orcid":"https://orcid.org/0009-0009-5719-3628","observed_orcids":["https://orcid.org/0009-0009-5719-3628"]},"institutions":[{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I4391767982","display_name":"State Key Laboratory of Cancer Biology","ror":"https://ror.org/01b280561","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391767982","https://openalex.org/I9916479"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Chao Wang","raw_affiliation_strings":["Department of Pathology, The General Hospital of Western Theater Command, Chengdu, 610083, China; State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China. Electronic address: wang_chao1987@126.com","Department of Pathology, The General Hospital of Western Theater Command, Chengdu, 610083, China","State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The General Hospital of Western Theater Command, Chengdu, 610083, China; State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China. Electronic address: wang_chao1987@126.com","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I4391767982","https://openalex.org/I9916479"]},{"raw_affiliation_string":"Department of Pathology, The General Hospital of Western Theater Command, Chengdu, 610083, China","institution_ids":[]},{"raw_affiliation_string":"State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I4391767982","https://openalex.org/I9916479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100334738","display_name":"Yuan Yuan","orcid":"https://orcid.org/0000-0002-0133-6898","observed_orcids":["https://orcid.org/0000-0002-0133-6898"]},"institutions":[{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I4391767982","display_name":"State Key Laboratory of Cancer Biology","ror":"https://ror.org/01b280561","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391767982","https://openalex.org/I9916479"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuan Yuan","raw_affiliation_strings":["State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I4391767982","https://openalex.org/I9916479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112535306","display_name":"Jie Wu","orcid":"https://orcid.org/0000-0002-9877-1764","observed_orcids":["https://orcid.org/0000-0002-9877-1764"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jie Wu","raw_affiliation_strings":["Department of Pathology, No.944 Hospital of PLA, Jiuquan, 735099, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, No.944 Hospital of PLA, Jiuquan, 735099, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103629309","display_name":"Yuanlin Zhao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I4391767982","display_name":"State Key Laboratory of Cancer Biology","ror":"https://ror.org/01b280561","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391767982","https://openalex.org/I9916479"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuanlin Zhao","raw_affiliation_strings":["State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I4391767982","https://openalex.org/I9916479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004341742","display_name":"Xing Gao","orcid":"https://orcid.org/0000-0002-7410-4051","observed_orcids":["https://orcid.org/0000-0002-7410-4051"]},"institutions":[{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I4391767982","display_name":"State Key Laboratory of Cancer Biology","ror":"https://ror.org/01b280561","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391767982","https://openalex.org/I9916479"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xing Gao","raw_affiliation_strings":["State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I4391767982","https://openalex.org/I9916479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047949320","display_name":"Yihua Chen","orcid":"https://orcid.org/0000-0003-1733-7980","observed_orcids":["https://orcid.org/0000-0003-1733-7980"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yihua Chen","raw_affiliation_strings":["Department of Pathology, The General Hospital of Western Theater Command, Chengdu, 610083, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The General Hospital of Western Theater Command, Chengdu, 610083, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100677208","display_name":"Chao Sun","orcid":"https://orcid.org/0000-0002-9046-3142","observed_orcids":["https://orcid.org/0000-0002-9046-3142","https://orcid.org/0009-0004-4796-5974","https://orcid.org/0009-0007-8719-9970"]},"institutions":[{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I4391767982","display_name":"State Key Laboratory of Cancer Biology","ror":"https://ror.org/01b280561","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391767982","https://openalex.org/I9916479"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chao Sun","raw_affiliation_strings":["State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I4391767982","https://openalex.org/I9916479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102766133","display_name":"Liming Xiao","orcid":"https://orcid.org/0000-0002-8397-8682","observed_orcids":["https://orcid.org/0000-0002-8397-8682"]},"institutions":[{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I4391767982","display_name":"State Key Laboratory of Cancer Biology","ror":"https://ror.org/01b280561","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391767982","https://openalex.org/I9916479"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liming Xiao","raw_affiliation_strings":["State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I4391767982","https://openalex.org/I9916479"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Pengfei Zheng","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pengfei Zheng","raw_affiliation_strings":["Department of Cardiology, The Sixteenth Hospital of PLA, Aletai, 836500, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, The Sixteenth Hospital of PLA, Aletai, 836500, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108492567","display_name":"Peizhen Hu","orcid":"https://orcid.org/0000-0002-8024-8465","observed_orcids":["https://orcid.org/0000-0002-8024-8465"]},"institutions":[{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I4391767982","display_name":"State Key Laboratory of Cancer Biology","ror":"https://ror.org/01b280561","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391767982","https://openalex.org/I9916479"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peizhen Hu","raw_affiliation_strings":["State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I4391767982","https://openalex.org/I9916479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101701156","display_name":"Zengshan Li","orcid":"https://orcid.org/0000-0002-3368-1434","observed_orcids":["https://orcid.org/0000-0002-3368-1434"]},"institutions":[{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I4391767982","display_name":"State Key Laboratory of Cancer Biology","ror":"https://ror.org/01b280561","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391767982","https://openalex.org/I9916479"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zengshan Li","raw_affiliation_strings":["State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I4391767982","https://openalex.org/I9916479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100407668","display_name":"Zhe Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I4391767982","display_name":"State Key Laboratory of Cancer Biology","ror":"https://ror.org/01b280561","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391767982","https://openalex.org/I9916479"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhe Wang","raw_affiliation_strings":["State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I4391767982","https://openalex.org/I9916479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100394422","display_name":"Jing Ye","orcid":"https://orcid.org/0000-0003-4471-5481","observed_orcids":["https://orcid.org/0000-0003-4471-5481"]},"institutions":[{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I4391767982","display_name":"State Key Laboratory of Cancer Biology","ror":"https://ror.org/01b280561","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391767982","https://openalex.org/I9916479"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jing Ye","raw_affiliation_strings":["State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China. Electronic address: yejing@fmmu.edu.cn","State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China. Electronic address: yejing@fmmu.edu.cn","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I4391767982","https://openalex.org/I9916479"]},{"raw_affiliation_string":"State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I4391767982","https://openalex.org/I9916479"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5115603699","display_name":"Lijun Zhang","orcid":"https://orcid.org/0000-0003-4974-2745","observed_orcids":["https://orcid.org/0000-0003-4974-2745"]},"institutions":[{"id":"https://openalex.org/I4210154136","display_name":"Tang Du Hospital","ror":"https://ror.org/04yvdan45","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210154136"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Lijun Zhang","raw_affiliation_strings":["Department of Clinical Diagnosis, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China. Electronic address: zhanglijun_fmmu@163.com","Department of Clinical Diagnosis, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Diagnosis, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China. Electronic address: zhanglijun_fmmu@163.com","institution_ids":["https://openalex.org/I4210154136","https://openalex.org/I9916479"]},{"raw_affiliation_string":"Department of Clinical Diagnosis, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China","institution_ids":["https://openalex.org/I4210154136","https://openalex.org/I9916479"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5100394422","https://openalex.org/A5100407178","https://openalex.org/A5115603699"],"corresponding_institution_ids":["https://openalex.org/I4210154136","https://openalex.org/I4210158926","https://openalex.org/I4391767982","https://openalex.org/I9916479"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":null,"fwci":3.5983,"has_fulltext":false,"cited_by_count":57,"citation_normalized_percentile":{"value":0.94257096,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"141","issue":null,"first_page":"372","last_page":"382"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.4408999979496002,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.4408999979496002,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.21250000596046448,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.179299995303154,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/perilipin-5","display_name":"perilipin 5","score":0.9559999704360962},{"id":"https://openalex.org/keywords/cardiac-hypertrophy","display_name":"cardiac hypertrophy","score":0.8690000176429749},{"id":"https://openalex.org/keywords/heart-failure","display_name":"heart failure","score":0.9990000128746033},{"id":"https://openalex.org/keywords/pressure-overload","display_name":"pressure overload","score":0.9210000038146973},{"id":"https://openalex.org/keywords/transverse-aortic-constriction","display_name":"transverse aortic constriction","score":0.8980000019073486},{"id":"https://openalex.org/keywords/fatty-acid-beta-oxidation","display_name":"fatty acid beta-oxidation","score":0.843999981880188},{"id":"https://openalex.org/keywords/lipid-droplets","display_name":"lipid droplets","score":0.8730000257492065},{"id":"https://openalex.org/keywords/triglyceride-storage","display_name":"triglyceride storage","score":0.8339999914169312},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.8999999761581421},{"id":"https://openalex.org/keywords/pparalpha","display_name":"PPAR\u03b1","score":0.9430000185966492},{"id":"https://openalex.org/keywords/pgc-1alpha","display_name":"PGC-1\u03b1","score":1.0},{"id":"https://openalex.org/keywords/mitochondrial-proliferation","display_name":"mitochondrial proliferation","score":0.9570000171661377},{"id":"https://openalex.org/keywords/lipotoxicity","display_name":"lipotoxicity","score":0.9279999732971191},{"id":"https://openalex.org/keywords/cardiomyocytes","display_name":"cardiomyocytes","score":0.7200000286102295},{"id":"https://openalex.org/keywords/energy-metabolism","display_name":"energy metabolism","score":0.6169999837875366}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8022317886352539},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7621292471885681},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.6961973905563354},{"id":"https://openalex.org/C140985366","wikidata":"https://www.wikidata.org/wiki/Q898489","display_name":"Lipolysis","level":3,"score":0.6910129189491272},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.6312121152877808},{"id":"https://openalex.org/C82714985","wikidata":"https://www.wikidata.org/wiki/Q306213","display_name":"Beta oxidation","level":3,"score":0.5632256865501404},{"id":"https://openalex.org/C44353895","wikidata":"https://www.wikidata.org/wiki/Q6556772","display_name":"Lipotoxicity","level":4,"score":0.554031491279602},{"id":"https://openalex.org/C25095133","wikidata":"https://www.wikidata.org/wiki/Q573950","display_name":"Lipid droplet","level":2,"score":0.5007526874542236},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.48990505933761597},{"id":"https://openalex.org/C167414201","wikidata":"https://www.wikidata.org/wiki/Q1955391","display_name":"Muscle hypertrophy","level":2,"score":0.4790019690990448},{"id":"https://openalex.org/C2778271984","wikidata":"https://www.wikidata.org/wiki/Q17126794","display_name":"Pressure overload","level":4,"score":0.47662270069122314},{"id":"https://openalex.org/C207200792","wikidata":"https://www.wikidata.org/wiki/Q428914","display_name":"Myocyte","level":2,"score":0.4311123788356781},{"id":"https://openalex.org/C57600042","wikidata":"https://www.wikidata.org/wiki/Q227564","display_name":"Oxidative phosphorylation","level":2,"score":0.42766398191452026},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.34804636240005493},{"id":"https://openalex.org/C3018791406","wikidata":"https://www.wikidata.org/wiki/Q945225","display_name":"Cardiac hypertrophy","level":3,"score":0.25557366013526917},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.20919975638389587},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.19720986485481262},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.1780892014503479},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1114773154258728},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.0802696943283081}],"mesh":[{"descriptor_ui":"D000070797","descriptor_name":"Perilipin-5","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D000070797","descriptor_name":"Perilipin-5","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005227","descriptor_name":"Fatty Acids","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005227","descriptor_name":"Fatty Acids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006332","descriptor_name":"Cardiomegaly","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006332","descriptor_name":"Cardiomegaly","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006332","descriptor_name":"Cardiomegaly","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009200","descriptor_name":"Myocardial Contraction","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011312","descriptor_name":"Pressure","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D014280","descriptor_name":"Triglycerides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015227","descriptor_name":"Lipid Peroxidation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D032383","descriptor_name":"Myocytes, Cardiac","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D032383","descriptor_name":"Myocytes, Cardiac","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D050356","descriptor_name":"Lipid Metabolism","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066292","descriptor_name":"Lipid Droplets","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.freeradbiomed.2019.07.006","doi":"https://doi.org/10.1016/j.freeradbiomed.2019.07.006","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.freeradbiomed.2019.07.006","pdf_url":null,"source":{"id":"https://openalex.org/S128018148","display_name":"Free Radical Biology and Medicine","issn_l":"0891-5849","issn":["0891-5849","1873-4596"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Free Radical Biology and Medicine","raw_type":"journal-article"},{"id":"pmid:31291602","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31291602","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Free radical biology & medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1310412337","display_name":"Perilipin 5\u5728\u9aa8\u9abc\u808c\u635f\u4f24\u540e\u518d\u751f\u548c\u4fee\u590d\u4e2d\u7684\u4f5c\u7528\u673a\u5236\u7814\u7a76","funder_award_id":"31671416","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4480516489","display_name":null,"funder_award_id":"81670792","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4854124272","display_name":null,"funder_award_id":"81700766","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7489626030","display_name":null,"funder_award_id":"81670792, 31671416","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W1967600689","https://openalex.org/W1973359170","https://openalex.org/W1974077951","https://openalex.org/W1979363352","https://openalex.org/W1989863035","https://openalex.org/W1990351735","https://openalex.org/W1992890029","https://openalex.org/W2017477539","https://openalex.org/W2025366893","https://openalex.org/W2032518511","https://openalex.org/W2033613500","https://openalex.org/W2037233461","https://openalex.org/W2060905615","https://openalex.org/W2071518542","https://openalex.org/W2082937995","https://openalex.org/W2084516396","https://openalex.org/W2084885690","https://openalex.org/W2094657005","https://openalex.org/W2102797065","https://openalex.org/W2105265053","https://openalex.org/W2108091822","https://openalex.org/W2121233961","https://openalex.org/W2121966499","https://openalex.org/W2125219081","https://openalex.org/W2126326715","https://openalex.org/W2128606426","https://openalex.org/W2130016382","https://openalex.org/W2133818377","https://openalex.org/W2150197543","https://openalex.org/W2154382589","https://openalex.org/W2155428717","https://openalex.org/W2159758687","https://openalex.org/W2165274786","https://openalex.org/W2205671666","https://openalex.org/W2215635770","https://openalex.org/W2238800297","https://openalex.org/W2310900891","https://openalex.org/W2334499091","https://openalex.org/W2409263517","https://openalex.org/W2508316944","https://openalex.org/W2590921889","https://openalex.org/W2762032744","https://openalex.org/W2790360897","https://openalex.org/W2910979721","https://openalex.org/W6671160217"],"related_works":["https://openalex.org/W4386423757","https://openalex.org/W3117071159","https://openalex.org/W2944307659","https://openalex.org/W4372231536","https://openalex.org/W2110734560","https://openalex.org/W2142178488","https://openalex.org/W4408535582","https://openalex.org/W2032518511","https://openalex.org/W2215635770","https://openalex.org/W2980907907"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":13},{"year":2025,"cited_by_count":11},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":5}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2019-07-12T00:00:00"}