{"id":"https://openalex.org/W2952770035","doi":"https://doi.org/10.1016/s0040-4039(00)00662-6","title":"Syntheses and binding studies of oligonucleotides containing N-hydroxycarbamate linkages: potential DNA cleaving antisense oligomers","display_name":"Syntheses and binding studies of oligonucleotides containing N-hydroxycarbamate linkages: potential DNA cleaving antisense oligomers","publication_year":2000,"publication_date":"2000-06-01","ids":{"openalex":"https://openalex.org/W2952770035","doi":"https://doi.org/10.1016/s0040-4039(00)00662-6","mag":"2952770035"},"language":"en","primary_location":{"id":"doi:10.1016/s0040-4039(00)00662-6","doi":"https://doi.org/10.1016/s0040-4039(00)00662-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0040-4039(00)00662-6","pdf_url":null,"source":{"id":"https://openalex.org/S133942674","display_name":"Tetrahedron Letters","issn_l":"0040-4039","issn":["0040-4039","1873-3581"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tetrahedron Letters","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100423945","display_name":"Hui Li","orcid":"https://orcid.org/0000-0003-0551-9912","observed_orcids":["https://orcid.org/0000-0003-0551-9912"]},"institutions":[{"id":"https://openalex.org/I107639228","display_name":"University of Notre Dame","ror":"https://ror.org/00mkhxb43","country_code":"US","type":"education","lineage":["https://openalex.org/I107639228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hui Li","raw_affiliation_strings":["Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA","institution_ids":["https://openalex.org/I107639228"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091265699","display_name":"Marvin J. Miller","orcid":"https://orcid.org/0000-0002-3704-8214","observed_orcids":["https://orcid.org/0000-0002-3704-8214"]},"institutions":[{"id":"https://openalex.org/I107639228","display_name":"University of Notre Dame","ror":"https://ror.org/00mkhxb43","country_code":"US","type":"education","lineage":["https://openalex.org/I107639228"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Marvin J Miller","raw_affiliation_strings":["Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA","institution_ids":["https://openalex.org/I107639228"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5091265699"],"corresponding_institution_ids":["https://openalex.org/I107639228"],"apc_list":{"value":3610,"currency":"USD","value_usd":3610},"apc_paid":null,"fwci":0.4823,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.62556738,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"41","issue":"22","first_page":"4323","last_page":"4327"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13105","display_name":"Synthesis and pharmacology of benzodiazepine derivatives","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oligonucleotide-synthesis","display_name":"oligonucleotide synthesis","score":0.8579999804496765},{"id":"https://openalex.org/keywords/thymidine-dimers","display_name":"thymidine dimers","score":0.8619999885559082},{"id":"https://openalex.org/keywords/antisense-oligomers","display_name":"antisense oligomers","score":0.7200000286102295},{"id":"https://openalex.org/keywords/dna-cleavage","display_name":"DNA cleavage","score":0.8679999709129333},{"id":"https://openalex.org/keywords/dna-duplex-binding","display_name":"DNA duplex binding","score":0.5450000166893005},{"id":"https://openalex.org/keywords/iron-binding","display_name":"iron binding","score":0.5770000219345093},{"id":"https://openalex.org/keywords/nuclease-resistance","display_name":"nuclease resistance","score":0.8169999718666077},{"id":"https://openalex.org/keywords/s1-nuclease","display_name":"S1 nuclease","score":0.8489999771118164},{"id":"https://openalex.org/keywords/chemically-modified-oligonucleotides","display_name":"modified oligonucleotides","score":0.7429999709129333}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9145755767822266},{"id":"https://openalex.org/C129312508","wikidata":"https://www.wikidata.org/wiki/Q133686","display_name":"Oligonucleotide","level":3,"score":0.8984779715538025},{"id":"https://openalex.org/C2777271071","wikidata":"https://www.wikidata.org/wiki/Q422529","display_name":"Nuclease","level":3,"score":0.8938208222389221},{"id":"https://openalex.org/C2780642029","wikidata":"https://www.wikidata.org/wiki/Q726004","display_name":"Oligomer","level":2,"score":0.771589994430542},{"id":"https://openalex.org/C2777108182","wikidata":"https://www.wikidata.org/wiki/Q422464","display_name":"Thymidine","level":3,"score":0.7563241720199585},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.6535420417785645},{"id":"https://openalex.org/C2779546866","wikidata":"https://www.wikidata.org/wiki/Q531306","display_name":"Dimer","level":2,"score":0.6468654870986938},{"id":"https://openalex.org/C2777028655","wikidata":"https://www.wikidata.org/wiki/Q415601","display_name":"Endonuclease","level":3,"score":0.5834237933158875},{"id":"https://openalex.org/C111921641","wikidata":"https://www.wikidata.org/wiki/Q80756","display_name":"Polynucleotide","level":2,"score":0.4573506712913513},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.40951502323150635},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.38892239332199097},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3556837737560272},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.10271179676055908},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.09071022272109985}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0040-4039(00)00662-6","doi":"https://doi.org/10.1016/s0040-4039(00)00662-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0040-4039(00)00662-6","pdf_url":null,"source":{"id":"https://openalex.org/S133942674","display_name":"Tetrahedron Letters","issn_l":"0040-4039","issn":["0040-4039","1873-3581"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tetrahedron Letters","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W345007868","https://openalex.org/W566149800","https://openalex.org/W573732864","https://openalex.org/W641636675","https://openalex.org/W1989367342","https://openalex.org/W2025502585","https://openalex.org/W2092975717","https://openalex.org/W2096023285","https://openalex.org/W2111100255","https://openalex.org/W2480582856","https://openalex.org/W2950723745","https://openalex.org/W2978308998"],"related_works":["https://openalex.org/W2119739704","https://openalex.org/W2044750617","https://openalex.org/W2015452625","https://openalex.org/W1983870882","https://openalex.org/W2052718369","https://openalex.org/W2115357551","https://openalex.org/W2045742500","https://openalex.org/W2950444854","https://openalex.org/W2068837802","https://openalex.org/W1973463137"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2019-06-27T00:00:00"}