{"id":"https://openalex.org/W2952723345","doi":"https://doi.org/10.1038/s41598-017-14922-8","title":"A Method for Quantifying Molecular Interactions Using Stochastic Modelling and Super-Resolution Microscopy","display_name":"A Method for Quantifying Molecular Interactions Using Stochastic Modelling and Super-Resolution Microscopy","publication_year":2017,"publication_date":"2017-10-26","ids":{"openalex":"https://openalex.org/W2952723345","doi":"https://doi.org/10.1038/s41598-017-14922-8","mag":"2952723345","pmid":"https://pubmed.ncbi.nlm.nih.gov/29093506","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5665986"},"language":"en","primary_location":{"id":"doi:10.1038/s41598-017-14922-8","doi":"https://doi.org/10.1038/s41598-017-14922-8","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-017-14922-8","pdf_url":"https://www.nature.com/articles/s41598-017-14922-8.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41598-017-14922-8.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086213678","display_name":"Keria Bermudez\u2010Hernandez","orcid":"https://orcid.org/0000-0002-7737-5797","observed_orcids":["https://orcid.org/0000-0002-7737-5797"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Keria Bermudez-Hernandez","raw_affiliation_strings":["Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA","Institute for Systems Genetics, New York University School of Medicine, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"Institute for Systems Genetics, New York University School of Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025650361","display_name":"Sarah Keegan","orcid":"https://orcid.org/0000-0001-8500-4876","observed_orcids":["https://orcid.org/0000-0001-8500-4876","https://orcid.org/0000-0003-3756-7767"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarah Keegan","raw_affiliation_strings":["Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA","Institute for Systems Genetics, New York University School of Medicine, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"Institute for Systems Genetics, New York University School of Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023457100","display_name":"Donna R. Whelan","orcid":"https://orcid.org/0000-0002-7078-5443","observed_orcids":["https://orcid.org/0000-0002-7078-5443"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Donna R. Whelan","raw_affiliation_strings":["Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026920899","display_name":"Dylan A. Reid","orcid":"https://orcid.org/0000-0001-6134-1165","observed_orcids":["https://orcid.org/0000-0001-6134-1165"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dylan A. Reid","raw_affiliation_strings":["Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110448755","display_name":"Jennifer Zagelbaum","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer Zagelbaum","raw_affiliation_strings":["Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086360774","display_name":"Yandong Yin","orcid":"https://orcid.org/0000-0003-2499-871X","observed_orcids":["https://orcid.org/0000-0003-2499-871X"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yandong Yin","raw_affiliation_strings":["Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059973732","display_name":"Sisi Ma","orcid":"https://orcid.org/0000-0003-2956-6844","observed_orcids":["https://orcid.org/0000-0003-2956-6844"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sisi Ma","raw_affiliation_strings":["Institute for Systems Genetics, New York University School of Medicine, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Systems Genetics, New York University School of Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081602466","display_name":"Eli Rothenberg","orcid":"https://orcid.org/0000-0002-1382-1380","observed_orcids":["https://orcid.org/0000-0002-1382-1380"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Eli Rothenberg","raw_affiliation_strings":["Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA. eli.rothenberg@nyumc.org","Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA. eli.rothenberg@nyumc.org","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065792746","display_name":"David Feny\u00f6","orcid":"https://orcid.org/0000-0001-5049-3825","observed_orcids":["https://orcid.org/0000-0001-5049-3825"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"David Feny\u00f6","raw_affiliation_strings":["Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA. david@fenyolab.org","Institute for Systems Genetics, New York University School of Medicine, New York, NY, USA. david@fenyolab.org","Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0001-5049-3825","affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA. david@fenyolab.org","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"Institute for Systems Genetics, New York University School of Medicine, New York, NY, USA. david@fenyolab.org","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I57206974"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5065792746","https://openalex.org/A5081602466"],"corresponding_institution_ids":["https://openalex.org/I57206974"],"apc_list":{"value":2690,"currency":"USD","value_usd":2690},"apc_paid":{"value":2690,"currency":"USD","value_usd":2690},"fwci":2.4467,"has_fulltext":true,"cited_by_count":30,"citation_normalized_percentile":{"value":0.89669007,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"7","issue":"1","first_page":"14882","last_page":"14882"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.8384000062942505,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.8384000062942505,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.15800000727176666,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interaction-factors","display_name":"interaction factors","score":0.9240000247955322},{"id":"https://openalex.org/keywords/super-resolution-microscopy","display_name":"super-resolution microscopy","score":0.7720000147819519},{"id":"https://openalex.org/keywords/stochastic-modeling","display_name":"stochastic modeling","score":0.9290000200271606},{"id":"https://openalex.org/keywords/cluster-overlap","display_name":"cluster overlap","score":0.7829999923706055},{"id":"https://openalex.org/keywords/imagej-plugin","display_name":"ImageJ plugin","score":0.7789999842643738},{"id":"https://openalex.org/keywords/image-analysis","display_name":"image analysis","score":0.3109999895095825}],"concepts":[{"id":"https://openalex.org/C2780009758","wikidata":"https://www.wikidata.org/wiki/Q6804172","display_name":"Measure (data warehouse)","level":2,"score":0.6811373829841614},{"id":"https://openalex.org/C164866538","wikidata":"https://www.wikidata.org/wiki/Q367351","display_name":"Cluster (spacecraft)","level":2,"score":0.6028584837913513},{"id":"https://openalex.org/C138268822","wikidata":"https://www.wikidata.org/wiki/Q1051925","display_name":"Resolution (logic)","level":2,"score":0.5717054009437561},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.5400524735450745},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5043424367904663},{"id":"https://openalex.org/C147080431","wikidata":"https://www.wikidata.org/wiki/Q1074953","display_name":"Microscopy","level":2,"score":0.4447234869003296},{"id":"https://openalex.org/C121864883","wikidata":"https://www.wikidata.org/wiki/Q677916","display_name":"Statistical physics","level":1,"score":0.44150251150131226},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.27007097005844116},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2688126266002655},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2534738779067993},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.19528499245643616},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1091776192188263},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D008722","descriptor_name":"Methods","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008853","descriptor_name":"Microscopy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D013269","descriptor_name":"Stochastic Processes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055592","descriptor_name":"Biophysical Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057054","descriptor_name":"Molecular Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1038/s41598-017-14922-8","doi":"https://doi.org/10.1038/s41598-017-14922-8","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-017-14922-8","pdf_url":"https://www.nature.com/articles/s41598-017-14922-8.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},{"id":"doi:10.1101/177063","doi":"https://doi.org/10.1101/177063","is_oa":true,"landing_page_url":"https://doi.org/10.1101/177063","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2017/08/17/177063.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:5665986","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5665986","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sci Rep","raw_type":"Text"},{"id":"pmid:29093506","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29093506","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific reports","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1038/s41598-017-14922-8","doi":"https://doi.org/10.1038/s41598-017-14922-8","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-017-14922-8","pdf_url":"https://www.nature.com/articles/s41598-017-14922-8.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1914842552","display_name":"Single-molecule studies of BRCA1-BACH1 mechanism in genomic integrity","funder_award_id":"5r21ca187612-02","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2182900872","display_name":"Proteogenomic Data Analysis for Cancer Systems Biology and Clinical Translation","funder_award_id":"U24CA210972","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G4571849628","display_name":null,"funder_award_id":"DMC-16-241-01","funder_id":"https://openalex.org/F4320306095","funder_display_name":"American Cancer Society"},{"id":"https://openalex.org/G5113856918","display_name":null,"funder_award_id":"R21-CA187612","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G5250076473","display_name":null,"funder_award_id":"R01-GM108119","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G5739276085","display_name":"Single-Molecule Studies of Non-Homologous DNA End Joining","funder_award_id":"5r01gm108119-05","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6145175089","display_name":null,"funder_award_id":"RSG DMC-16-241-01-DMC","funder_id":"https://openalex.org/F4320306095","funder_display_name":"American Cancer Society"},{"id":"https://openalex.org/G7731223918","display_name":"Molecular, Oncology and Immunology Training Grant","funder_award_id":"T32CA009161","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000135018","display_name":null,"funder_award_id":"CA009161","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000215172","display_name":null,"funder_award_id":"CA187612","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000275336","display_name":null,"funder_award_id":"GM108119","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306095","display_name":"American Cancer Society","ror":"https://ror.org/02e463172"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2952723345.pdf","grobid_xml":"https://content.openalex.org/works/W2952723345.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W1528731272","https://openalex.org/W1772403982","https://openalex.org/W1841331176","https://openalex.org/W1992858116","https://openalex.org/W1995311028","https://openalex.org/W2008392372","https://openalex.org/W2015404233","https://openalex.org/W2022050193","https://openalex.org/W2030667313","https://openalex.org/W2032101051","https://openalex.org/W2040483003","https://openalex.org/W2043891370","https://openalex.org/W2049763161","https://openalex.org/W2053106661","https://openalex.org/W2054455698","https://openalex.org/W2060187044","https://openalex.org/W2065154098","https://openalex.org/W2071798635","https://openalex.org/W2073576660","https://openalex.org/W2079372780","https://openalex.org/W2086397199","https://openalex.org/W2086470518","https://openalex.org/W2087850846","https://openalex.org/W2093861156","https://openalex.org/W2100726540","https://openalex.org/W2101336703","https://openalex.org/W2108767279","https://openalex.org/W2124733101","https://openalex.org/W2125782175","https://openalex.org/W2141083815","https://openalex.org/W2142349419","https://openalex.org/W2150737519","https://openalex.org/W2156853807","https://openalex.org/W2161921787","https://openalex.org/W2168493348","https://openalex.org/W2168816122","https://openalex.org/W2171142273","https://openalex.org/W2301058553","https://openalex.org/W2507974128"],"related_works":["https://openalex.org/W2799859111","https://openalex.org/W2215505233","https://openalex.org/W2137986749","https://openalex.org/W2073576660","https://openalex.org/W2559797133","https://openalex.org/W4408988654","https://openalex.org/W2122812646","https://openalex.org/W3006078944","https://openalex.org/W2055211642","https://openalex.org/W6911746191"],"abstract_inverted_index":{"We":[0,167],"introduce":[1],"the":[2,10,24,38,41,51,71,76,83,86,89,92,104,109,113,124,127,162,169,186],"Interaction":[3],"Factor":[4],"(IF),":[5],"a":[6,56,59],"measure":[7,158],"for":[8,55,126,184],"quantifying":[9],"interaction":[11,43,95,141],"of":[12,30,40,47,61,73,85,94,103,133,159,164,188],"molecular":[13,48],"clusters":[14,49,74,90],"in":[15,23,50,75,91,142],"super-resolution":[16],"microscopy":[17,143],"images.":[18],"The":[19,53,131],"IF":[20,54,107,125,134,170,187],"is":[21,28,63,120,145,148,155],"robust":[22],"sense":[25],"that":[26,146],"it":[27,34,147],"independent":[29],"cluster":[31,152],"density,":[32],"and":[33,108,154,176,179],"only":[35,118],"depends":[36],"on":[37],"extent":[39],"pair-wise":[42],"between":[44,88,106],"different":[45],"types":[46],"image.":[52,190],"single":[57],"or":[58],"collection":[60],"images":[62,77,144],"estimated":[64],"by":[65,172],"first":[66],"using":[67,173],"stochastic":[68],"modelling":[69],"where":[70],"locations":[72],"are":[78],"repeatedly":[79],"randomized":[80],"to":[81,122,136,139,150],"estimate":[82,123],"distribution":[84],"overlaps":[87],"absence":[93],"(IF":[96],"=":[97],"0).":[98],"Second,":[99],"an":[100,156,181,189],"analytical":[101],"form":[102],"relationship":[105],"overlap":[110,115],"(which":[111],"has":[112],"random":[114],"as":[116],"its":[117],"parameter)":[119],"used":[121],"experimentally":[128],"observed":[129],"overlap.":[130],"advantage":[132],"compared":[135],"conventional":[137],"methods":[138],"quantify":[140],"insensitive":[149],"changing":[151],"density":[153],"absolute":[157],"interaction,":[160],"making":[161],"interpretation":[163],"experiments":[165],"easier.":[166],"validate":[168],"method":[171],"both":[174],"simulated":[175],"experimental":[177],"data":[178],"provide":[180],"ImageJ":[182],"plugin":[183],"determining":[185]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-06-27T00:00:00"}