{"id":"https://openalex.org/W2952036327","doi":"https://doi.org/10.1002/etc.4516","title":"Coupled Application of Antioxidant Defense Response and Embryo Development in Amphipod Crustaceans in the Assessment of Sediment Toxicity","display_name":"Coupled Application of Antioxidant Defense Response and Embryo Development in Amphipod Crustaceans in the Assessment of Sediment Toxicity","publication_year":2019,"publication_date":"2019-06-12","ids":{"openalex":"https://openalex.org/W2952036327","doi":"https://doi.org/10.1002/etc.4516","mag":"2952036327","pmid":"https://pubmed.ncbi.nlm.nih.gov/31189019"},"language":"en","primary_location":{"id":"doi:10.1002/etc.4516","doi":"https://doi.org/10.1002/etc.4516","is_oa":false,"landing_page_url":"https://doi.org/10.1002/etc.4516","pdf_url":null,"source":{"id":"https://openalex.org/S136710263","display_name":"Environmental Toxicology and Chemistry","issn_l":"0730-7268","issn":["0730-7268","1552-8618"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-3","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental Toxicology and Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037248038","display_name":"\u041d. \u0410. \u0411\u0435\u0440\u0435\u0437\u0438\u043d\u0430","orcid":"https://orcid.org/0000-0003-3057-5596","observed_orcids":["https://orcid.org/0000-0003-3057-5596"]},"institutions":[{"id":"https://openalex.org/I2801680271","display_name":"Zoological Institute","ror":"https://ror.org/05snbjh64","country_code":"RU","type":"archive","lineage":["https://openalex.org/I1313323035","https://openalex.org/I2801680271","https://openalex.org/I4210129690"]}],"countries":["RU"],"is_corresponding":true,"raw_author_name":"Nadezhda A. Berezina","raw_affiliation_strings":["Zoological Institute Russian Academy of Sciences St. Petersburg Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zoological Institute Russian Academy of Sciences St. Petersburg Russia","institution_ids":["https://openalex.org/I2801680271"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064412175","display_name":"Kari K. Lehtonen","orcid":"https://orcid.org/0000-0002-7757-2336","observed_orcids":["https://orcid.org/0000-0002-7757-2336"]},"institutions":[{"id":"https://openalex.org/I2800424308","display_name":"Finnish Environment Institute","ror":"https://ror.org/013nat269","country_code":"FI","type":"government","lineage":["https://openalex.org/I2800424308","https://openalex.org/I4210136438"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Kari K. Lehtonen","raw_affiliation_strings":["Marine Research Center Finnish Environment Institute Helsinki Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marine Research Center Finnish Environment Institute Helsinki Finland","institution_ids":["https://openalex.org/I2800424308"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026982688","display_name":"Aino Ahvo","orcid":"https://orcid.org/0000-0002-8275-4863","observed_orcids":["https://orcid.org/0000-0002-8275-4863"]},"institutions":[{"id":"https://openalex.org/I2800424308","display_name":"Finnish Environment Institute","ror":"https://ror.org/013nat269","country_code":"FI","type":"government","lineage":["https://openalex.org/I2800424308","https://openalex.org/I4210136438"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Aino Ahvo","raw_affiliation_strings":["Marine Research Center Finnish Environment Institute Helsinki Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marine Research Center Finnish Environment Institute Helsinki Finland","institution_ids":["https://openalex.org/I2800424308"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5037248038"],"corresponding_institution_ids":["https://openalex.org/I2801680271"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.4124,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.51911686,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"38","issue":"9","first_page":"2020","last_page":"2031"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10447","display_name":"Environmental Toxicology and Ecotoxicology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10447","display_name":"Environmental Toxicology and Ecotoxicology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11004","display_name":"Crustacean biology and ecology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12071","display_name":"Marine Biology and Environmental Chemistry","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2212","display_name":"Ocean Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sediment-toxicity","display_name":"sediment toxicity","score":0.8199999928474426},{"id":"https://openalex.org/keywords/gmelinoides-fasciatus","display_name":"Gmelinoides fasciatus","score":0.9860000014305115},{"id":"https://openalex.org/keywords/amphipods","display_name":"Amphipoda","score":0.9139999747276306},{"id":"https://openalex.org/keywords/embryonic-malformations","display_name":"embryonic malformations","score":0.8330000042915344},{"id":"https://openalex.org/keywords/antioxidant-defense","display_name":"antioxidant defense","score":0.8569999933242798},{"id":"https://openalex.org/keywords/glutathione-s-transferase","display_name":"glutathione S-transferase","score":0.9800000190734863},{"id":"https://openalex.org/keywords/catalase","display_name":"catalase","score":0.9980000257492065},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.7049999833106995},{"id":"https://openalex.org/keywords/organotin-compounds","display_name":"organotin compounds","score":0.7829999923706055},{"id":"https://openalex.org/keywords/polycyclic-aromatic-hydrocarbons","display_name":"polycyclic aromatic hydrocarbons","score":1.0},{"id":"https://openalex.org/keywords/trace-metals","display_name":"trace metals","score":0.9430000185966492},{"id":"https://openalex.org/keywords/sublethal-effects","display_name":"sublethal effects","score":0.8119999766349792},{"id":"https://openalex.org/keywords/baltic-sea-sediments","display_name":"Baltic Sea sediments","score":0.6620000004768372},{"id":"https://openalex.org/keywords/benthic-invertebrates","display_name":"benthic invertebrates","score":0.6779999732971191}],"concepts":[{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.6840265989303589},{"id":"https://openalex.org/C2778324211","wikidata":"https://www.wikidata.org/wiki/Q193418","display_name":"Amphipoda","level":3,"score":0.6757227778434753},{"id":"https://openalex.org/C2816523","wikidata":"https://www.wikidata.org/wiki/Q180184","display_name":"Sediment","level":2,"score":0.6159265041351318},{"id":"https://openalex.org/C115346097","wikidata":"https://www.wikidata.org/wiki/Q1412144","display_name":"Ecotoxicology","level":2,"score":0.5990722179412842},{"id":"https://openalex.org/C107872376","wikidata":"https://www.wikidata.org/wiki/Q321355","display_name":"Environmental chemistry","level":1,"score":0.5828915238380432},{"id":"https://openalex.org/C84766238","wikidata":"https://www.wikidata.org/wiki/Q25364","display_name":"Crustacean","level":2,"score":0.5689482092857361},{"id":"https://openalex.org/C184112429","wikidata":"https://www.wikidata.org/wiki/Q476174","display_name":"Serial dilution","level":3,"score":0.5388635396957397},{"id":"https://openalex.org/C2779078112","wikidata":"https://www.wikidata.org/wiki/Q13462192","display_name":"Tributyltin","level":2,"score":0.5269485116004944},{"id":"https://openalex.org/C2778979269","wikidata":"https://www.wikidata.org/wiki/Q106951292","display_name":"Catalase","level":3,"score":0.5090619921684265},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4866355359554291},{"id":"https://openalex.org/C161176658","wikidata":"https://www.wikidata.org/wiki/Q131656","display_name":"Pesticide","level":2,"score":0.47599685192108154},{"id":"https://openalex.org/C33070731","wikidata":"https://www.wikidata.org/wiki/Q7218","display_name":"Toxicology","level":1,"score":0.4390966296195984},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.4105321764945984},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3066931366920471},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.2305993139743805},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.06865003705024719},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008670","descriptor_name":"Metals","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D008670","descriptor_name":"Metals","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D009947","descriptor_name":"Organotin Compounds","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D009947","descriptor_name":"Organotin Compounds","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D011084","descriptor_name":"Polycyclic Aromatic Hydrocarbons","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D011084","descriptor_name":"Polycyclic Aromatic Hydrocarbons","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D014874","descriptor_name":"Water Pollutants, Chemical","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D014874","descriptor_name":"Water Pollutants, Chemical","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D017753","descriptor_name":"Ecosystem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018675","descriptor_name":"Toxicity Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019015","descriptor_name":"Geologic Sediments","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D033304","descriptor_name":"Amphipoda","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D033304","descriptor_name":"Amphipoda","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D047108","descriptor_name":"Embryonic Development","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1002/etc.4516","doi":"https://doi.org/10.1002/etc.4516","is_oa":false,"landing_page_url":"https://doi.org/10.1002/etc.4516","pdf_url":null,"source":{"id":"https://openalex.org/S136710263","display_name":"Environmental Toxicology and Chemistry","issn_l":"0730-7268","issn":["0730-7268","1552-8618"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-3","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental Toxicology and Chemistry","raw_type":"journal-article"},{"id":"pmid:31189019","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31189019","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental toxicology and chemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/14","display_name":"Life below water","score":0.7778000235557556}],"study_designs":[],"awards":[{"id":"https://openalex.org/G176855851","display_name":null,"funder_award_id":"AAAA-A19-119020690091-0","funder_id":"https://openalex.org/F4320327494","funder_display_name":"Ministry of Science and Higher Education of the Russian Federation"}],"funders":[{"id":"https://openalex.org/F4320327494","display_name":"Ministry of Science and Higher Education of the Russian Federation","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":76,"referenced_works":["https://openalex.org/W83069026","https://openalex.org/W163857464","https://openalex.org/W562090581","https://openalex.org/W1581414347","https://openalex.org/W1601020072","https://openalex.org/W1963567443","https://openalex.org/W1963581538","https://openalex.org/W1977644023","https://openalex.org/W1978402074","https://openalex.org/W1980635267","https://openalex.org/W1982074402","https://openalex.org/W1983310681","https://openalex.org/W1985241714","https://openalex.org/W1985437310","https://openalex.org/W1989935180","https://openalex.org/W1990700067","https://openalex.org/W1998066541","https://openalex.org/W2002863294","https://openalex.org/W2003712365","https://openalex.org/W2009768522","https://openalex.org/W2014339733","https://openalex.org/W2020402367","https://openalex.org/W2020469902","https://openalex.org/W2028416986","https://openalex.org/W2030649941","https://openalex.org/W2033608514","https://openalex.org/W2041482318","https://openalex.org/W2042405053","https://openalex.org/W2043603584","https://openalex.org/W2048244792","https://openalex.org/W2052106398","https://openalex.org/W2053253422","https://openalex.org/W2053471764","https://openalex.org/W2057725366","https://openalex.org/W2061926351","https://openalex.org/W2062305998","https://openalex.org/W2065936538","https://openalex.org/W2068562416","https://openalex.org/W2070368751","https://openalex.org/W2077878418","https://openalex.org/W2078139350","https://openalex.org/W2078852634","https://openalex.org/W2080628914","https://openalex.org/W2082000634","https://openalex.org/W2086286755","https://openalex.org/W2086335026","https://openalex.org/W2087355873","https://openalex.org/W2088805002","https://openalex.org/W2090676022","https://openalex.org/W2101981388","https://openalex.org/W2107253044","https://openalex.org/W2108478452","https://openalex.org/W2110114372","https://openalex.org/W2117131042","https://openalex.org/W2122341467","https://openalex.org/W2128635872","https://openalex.org/W2130788049","https://openalex.org/W2136232719","https://openalex.org/W2157260867","https://openalex.org/W2163276670","https://openalex.org/W2182299533","https://openalex.org/W2290738188","https://openalex.org/W2329592333","https://openalex.org/W2515901410","https://openalex.org/W2523051083","https://openalex.org/W2527899288","https://openalex.org/W2592049992","https://openalex.org/W2599214289","https://openalex.org/W2610637675","https://openalex.org/W2896382581","https://openalex.org/W2993377945","https://openalex.org/W3006055117","https://openalex.org/W3206086938","https://openalex.org/W4300114837","https://openalex.org/W4300198507","https://openalex.org/W6603378380"],"related_works":["https://openalex.org/W2599214289","https://openalex.org/W2080628914","https://openalex.org/W3006546224","https://openalex.org/W2129608818","https://openalex.org/W2064504111","https://openalex.org/W1922758039","https://openalex.org/W321812784","https://openalex.org/W7097851463","https://openalex.org/W2058832509","https://openalex.org/W2065926385"],"abstract_inverted_index":{"Abstract":[0],"Survival":[1],"rate,":[2],"frequency":[3],"of":[4,28,36,66,83,123,152,161,216,227,231,244,250,253],"malformed":[5],"embryos,":[6],"and":[7,31,76,108,134,137,169,190,234,247],"antioxidant":[8,184,235],"defense":[9,185,236],"system":[10,186,237],"responses":[11,207],"in":[12,39,131,157,165,175,182,194,218,239,241,256],"the":[13,19,26,34,49,77,84,132,142,162,166,176,183,198,203,214,219,225,228,242],"benthic":[14],"amphipod":[15,163],"Gmelinoides":[16],"fasciatus":[17,125],"from":[18,48,56,72,141],"Baltic":[20,50],"Sea":[21,51],"were":[22,155,192],"measured":[23],"to":[24,32,60,74,139,159,197],"examine":[25],"effects":[27,252],"toxic":[29],"sediments,":[30],"assess":[33],"usefulness":[35],"these":[37],"endpoints":[38],"sediment":[40,46,55,86,245],"toxicity":[41,127],"biotesting.":[42],"A":[43],"highly":[44],"contaminated":[45,199],"sample":[47],"was":[52,87,129],"diluted":[53],"with":[54,63,70,172,202,206,213],"a":[57,64,147],"clean":[58],"site":[59],"come":[61],"up":[62],"series":[65],"5":[67],"test":[68,85],"sediments":[69,200],"dilutions":[71],"1:32":[73,81],"1:1024,":[75],"reference":[78,133,177,204],"sediment.":[79],"The":[80,120,221],"dilution":[82,144],"analyzed":[88],"for":[89],"organotins":[90],"(2862":[91],"\u00b5g":[92,103],"tin":[93],"[Sn]":[94],"kg":[95,104,116],"dry":[96,105,117],"wt":[97,106,118],"\u20131),":[98,107],"polycyclic":[99],"aromatic":[100],"hydrocarbons":[101],"(6064":[102],"selected":[109],"trace":[110],"metals":[111],"(e.g.,":[112],"copper":[113],"352":[114],"mg":[115],"\u20131).":[119],"survival":[121],"rate":[122],"G.":[124],"(10-d":[126],"test)":[128],"100%":[130],"1:1024":[135],"treatments,":[136],"began":[138],"decline":[140],"1:256":[143,170],"onward.":[145],"In":[146],"28-d":[148],"experiment,":[149],"various":[150],"types":[151],"morphological":[153],"malformations":[154,217,233],"observed":[156,193],"11":[158],"80%":[160],"embryos":[164],"1:64,":[167],"1:128,":[168],"dilutions,":[171],"only":[173],"<5%":[174],"treatment.":[178],"Also,":[179],"elevated":[180],"activities":[181],"enzymes":[187],"glutathione":[188],"S-transferase":[189],"catalase":[191],"amphipods":[195,240],"exposed":[196],"compared":[201,212],"treatment,":[205],"at":[208],"lower":[209],"contamination":[210,255],"levels":[211],"appearance":[215],"embryos.":[220],"results":[222],"obtained":[223],"illustrate":[224],"effectiveness":[226],"combined":[229],"application":[230],"embryonic":[232],"biomarkers":[238],"assessment":[243],"toxicity,":[246],"potentially":[248],"also":[249],"sublethal":[251],"chemical":[254],"aquatic":[257],"ecosystems.":[258],"Environ":[259],"Toxicol":[260],"Chem":[261],"2019;38:2020\u20132031.":[262],"\u00a9":[263],"2019":[264],"SETAC.":[265]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2019-06-27T00:00:00"}