{"id":"https://openalex.org/W2952010976","doi":"https://doi.org/10.1093/jnen/nlz045","title":"Mild Chronic Traumatic Encephalopathy Neuropathology in People With No Known Participation in Contact Sports or History of Repetitive Neurotrauma","display_name":"Mild Chronic Traumatic Encephalopathy Neuropathology in People With No Known Participation in Contact Sports or History of Repetitive Neurotrauma","publication_year":2019,"publication_date":"2019-06-06","ids":{"openalex":"https://openalex.org/W2952010976","doi":"https://doi.org/10.1093/jnen/nlz045","mag":"2952010976","pmid":"https://pubmed.ncbi.nlm.nih.gov/31169877","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6581557"},"language":"en","primary_location":{"id":"doi:10.1093/jnen/nlz045","doi":"https://doi.org/10.1093/jnen/nlz045","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jnen/nlz045","pdf_url":"https://academic.oup.com/jnen/article-pdf/78/7/615/28838299/nlz045.pdf","source":{"id":"https://openalex.org/S38023437","display_name":"Journal of Neuropathology & Experimental Neurology","issn_l":"0022-3069","issn":["0022-3069","1554-6578"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuropathology &amp; Experimental Neurology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/jnen/article-pdf/78/7/615/28838299/nlz045.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021760618","display_name":"Grant L. Iverson","orcid":"https://orcid.org/0000-0001-7348-9570","observed_orcids":["https://orcid.org/0000-0001-7348-9570"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2799748957","display_name":"Spaulding Rehabilitation Hospital","ror":"https://ror.org/011dvr318","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799748957","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4405272316","display_name":"Schoen Adams Research Institute at Spaulding Rehabilitation","ror":"https://ror.org/03z41bq39","country_code":"US","type":"facility","lineage":["https://openalex.org/I4405272316"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Grant L Iverson","raw_affiliation_strings":["Department of Physical Medicine and Rehabilitation, Harvard Medical School","Home Base, A Red Sox Foundation and Massachusetts General Hospital Program, Boston, Massachusetts","MassGeneral Hospital for Children\u2122 Sports Concussion Program","Spaulding Rehabilitation Hospital, Spaulding Research Institute"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physical Medicine and Rehabilitation, Harvard Medical School","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Home Base, A Red Sox Foundation and Massachusetts General Hospital Program, Boston, Massachusetts","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"MassGeneral Hospital for Children\u2122 Sports Concussion Program","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Spaulding Rehabilitation Hospital, Spaulding Research Institute","institution_ids":["https://openalex.org/I2799748957","https://openalex.org/I4405272316"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004917036","display_name":"Teemu M. Luoto","orcid":"https://orcid.org/0000-0002-7329-3284","observed_orcids":["https://orcid.org/0000-0002-7329-3284"]},"institutions":[{"id":"https://openalex.org/I4210126318","display_name":"Tampere University Hospital","ror":"https://ror.org/02hvt5f17","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I4210126318"]},{"id":"https://openalex.org/I4387153886","display_name":"University of Tampere","ror":"https://ror.org/05p6qqk79","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Teemu M Luoto","raw_affiliation_strings":["Department of Neurosurgery, Tampere University Hospital and University of Tampere, Tampere, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Tampere University Hospital and University of Tampere, Tampere, Finland","institution_ids":["https://openalex.org/I4210126318","https://openalex.org/I4387153886"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065030179","display_name":"Pekka J. Karhunen","orcid":"https://orcid.org/0000-0002-0320-571X","observed_orcids":["https://orcid.org/0000-0002-0320-571X"]},"institutions":[{"id":"https://openalex.org/I166825849","display_name":"Tampere University","ror":"https://ror.org/033003e23","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849"]},{"id":"https://openalex.org/I4210133601","display_name":"Fimlab (Finland)","ror":"https://ror.org/031y6w871","country_code":"FI","type":"company","lineage":["https://openalex.org/I4210133601"]},{"id":"https://openalex.org/I4387153886","display_name":"University of Tampere","ror":"https://ror.org/05p6qqk79","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Pekka J Karhunen","raw_affiliation_strings":["Department of Forensic Medicine, Faculty of Medicine and Life Sciences, University of Tampere","Fimlab Laboratories and Finnish Cardiovascular Research Center Tampere, Tampere, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Forensic Medicine, Faculty of Medicine and Life Sciences, University of Tampere","institution_ids":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]},{"raw_affiliation_string":"Fimlab Laboratories and Finnish Cardiovascular Research Center Tampere, Tampere, Finland","institution_ids":["https://openalex.org/I4210133601"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007315276","display_name":"Rudolph J. Castellani","orcid":"https://orcid.org/0000-0002-5414-3184","observed_orcids":["https://orcid.org/0000-0002-5414-3184"]},"institutions":[{"id":"https://openalex.org/I12097938","display_name":"West Virginia University","ror":"https://ror.org/011vxgd24","country_code":"US","type":"education","lineage":["https://openalex.org/I12097938"]},{"id":"https://openalex.org/I4210089362","display_name":"Blanchette Rockefeller Neurosciences Institute","ror":"https://ror.org/005535379","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I12097938","https://openalex.org/I2802882910","https://openalex.org/I4210089362"]},{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rudolph J Castellani","raw_affiliation_strings":["Department of Neuroscience, Rockefeller Neuroscience Institute","Department of Pathology, Anatomy and Laboratory Medicine","West Virginia University School of Medicine, Morgantown, West Virginia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Rockefeller Neuroscience Institute","institution_ids":["https://openalex.org/I4210089362","https://openalex.org/I83399316"]},{"raw_affiliation_string":"Department of Pathology, Anatomy and Laboratory Medicine","institution_ids":[]},{"raw_affiliation_string":"West Virginia University School of Medicine, Morgantown, West Virginia","institution_ids":["https://openalex.org/I12097938"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5021760618"],"corresponding_institution_ids":["https://openalex.org/I136199984","https://openalex.org/I2799748957","https://openalex.org/I4210087915","https://openalex.org/I4405272316"],"apc_list":{"value":5036,"currency":"USD","value_usd":5036},"apc_paid":null,"fwci":6.1665,"has_fulltext":true,"cited_by_count":65,"citation_normalized_percentile":{"value":0.97421003,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":100},"biblio":{"volume":"78","issue":"7","first_page":"615","last_page":"625"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10416","display_name":"Traumatic Brain Injury Research","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10416","display_name":"Traumatic Brain Injury Research","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-traumatic-encephalopathy","display_name":"chronic traumatic encephalopathy","score":1.0},{"id":"https://openalex.org/keywords/hyperphosphorylated-tau","display_name":"hyperphosphorylated tau","score":0.9139999747276306},{"id":"https://openalex.org/keywords/traumatic-brain-injury","display_name":"traumatic brain injury","score":0.75},{"id":"https://openalex.org/keywords/non-contact-sports","display_name":"non-contact sports","score":0.4189999997615814},{"id":"https://openalex.org/keywords/braak-stages","display_name":"Braak stages","score":0.6629999876022339},{"id":"https://openalex.org/keywords/postmortem-neuropathology","display_name":"postmortem neuropathology","score":0.6800000071525574},{"id":"https://openalex.org/keywords/men","display_name":"men","score":0.32499998807907104}],"concepts":[{"id":"https://openalex.org/C2911139526","wikidata":"https://www.wikidata.org/wiki/Q5114004","display_name":"Chronic traumatic encephalopathy","level":5,"score":0.9801173210144043},{"id":"https://openalex.org/C2780130745","wikidata":"https://www.wikidata.org/wiki/Q1650750","display_name":"Neuropathology","level":3,"score":0.7868674397468567},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6259528994560242},{"id":"https://openalex.org/C2781017439","wikidata":"https://www.wikidata.org/wiki/Q1995526","display_name":"Traumatic brain injury","level":2,"score":0.6098368763923645},{"id":"https://openalex.org/C2778426673","wikidata":"https://www.wikidata.org/wiki/Q326921","display_name":"Concussion","level":4,"score":0.5703250169754028},{"id":"https://openalex.org/C2781179581","wikidata":"https://www.wikidata.org/wiki/Q2857712","display_name":"Family history","level":2,"score":0.48923325538635254},{"id":"https://openalex.org/C2779504383","wikidata":"https://www.wikidata.org/wiki/Q41482","display_name":"Autopsy","level":2,"score":0.4214383363723755},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3924998641014099},{"id":"https://openalex.org/C3017944768","wikidata":"https://www.wikidata.org/wiki/Q1450463","display_name":"Poison control","level":2,"score":0.3343822658061981},{"id":"https://openalex.org/C190385971","wikidata":"https://www.wikidata.org/wiki/Q373494","display_name":"Injury prevention","level":3,"score":0.25327005982398987},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.23544985055923462},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.19228637218475342},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.14291879534721375},{"id":"https://openalex.org/C545542383","wikidata":"https://www.wikidata.org/wiki/Q2751242","display_name":"Medical emergency","level":1,"score":0.07321763038635254}],"mesh":[{"descriptor_ui":"D000070627","descriptor_name":"Chronic Traumatic Encephalopathy","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001253","descriptor_name":"Astrocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001344","descriptor_name":"Autopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001927","descriptor_name":"Brain Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D002908","descriptor_name":"Chronic Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010766","descriptor_name":"Phosphorylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013177","descriptor_name":"Sports","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016875","descriptor_name":"tau Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/jnen/nlz045","doi":"https://doi.org/10.1093/jnen/nlz045","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jnen/nlz045","pdf_url":"https://academic.oup.com/jnen/article-pdf/78/7/615/28838299/nlz045.pdf","source":{"id":"https://openalex.org/S38023437","display_name":"Journal of Neuropathology & Experimental Neurology","issn_l":"0022-3069","issn":["0022-3069","1554-6578"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuropathology &amp; Experimental Neurology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6581557","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6581557","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Neuropathol Exp Neurol","raw_type":"Text"},{"id":"pmid:31169877","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31169877","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neuropathology and experimental neurology","raw_type":"Journal Article"},{"id":"pmh:oai:biblioboard.com:246792f6-3f75-42d6-a9bc-c5defa17539d","doi":null,"is_oa":true,"landing_page_url":"https://openresearchlibrary.org/viewer/246792f6-3f75-42d6-a9bc-c5defa17539d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401131","display_name":"BiblioBoard Library Catalog (Open Research Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"MODID-759a0011d80:Morressier 2020-2021","raw_type":"OTHER_DOCUMENT"}],"best_oa_location":{"id":"doi:10.1093/jnen/nlz045","doi":"https://doi.org/10.1093/jnen/nlz045","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jnen/nlz045","pdf_url":"https://academic.oup.com/jnen/article-pdf/78/7/615/28838299/nlz045.pdf","source":{"id":"https://openalex.org/S38023437","display_name":"Journal of Neuropathology & Experimental Neurology","issn_l":"0022-3069","issn":["0022-3069","1554-6578"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuropathology &amp; Experimental Neurology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9922999739646912,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320309563","display_name":"Western Michigan University","ror":"https://ror.org/04j198w64"},{"id":"https://openalex.org/F4320310842","display_name":"Stryker","ror":"https://ror.org/043affe91"},{"id":"https://openalex.org/F4320315857","display_name":"Lieber Institute for Brain Development","ror":"https://ror.org/04q36wn27"},{"id":"https://openalex.org/F4320315885","display_name":"Australian Government","ror":"https://ror.org/0314h5y94"},{"id":"https://openalex.org/F4320318724","display_name":"National Football League Players Association","ror":"https://ror.org/03ftsw720"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2952010976.pdf","grobid_xml":"https://content.openalex.org/works/W2952010976.grobid-xml"},"referenced_works_count":58,"referenced_works":["https://openalex.org/W821579936","https://openalex.org/W929294836","https://openalex.org/W1157923211","https://openalex.org/W1534792373","https://openalex.org/W1590917599","https://openalex.org/W1879183898","https://openalex.org/W1944945174","https://openalex.org/W1967823816","https://openalex.org/W1970413515","https://openalex.org/W1971032265","https://openalex.org/W1985345440","https://openalex.org/W2012342339","https://openalex.org/W2035438756","https://openalex.org/W2037332170","https://openalex.org/W2043633971","https://openalex.org/W2048137511","https://openalex.org/W2052742260","https://openalex.org/W2054482051","https://openalex.org/W2067106012","https://openalex.org/W2077024919","https://openalex.org/W2081325915","https://openalex.org/W2084674974","https://openalex.org/W2084706926","https://openalex.org/W2085684925","https://openalex.org/W2106837589","https://openalex.org/W2107736622","https://openalex.org/W2110282732","https://openalex.org/W2111774300","https://openalex.org/W2115440332","https://openalex.org/W2127201752","https://openalex.org/W2128228199","https://openalex.org/W2134097886","https://openalex.org/W2140341262","https://openalex.org/W2141679195","https://openalex.org/W2146729934","https://openalex.org/W2150445605","https://openalex.org/W2151373091","https://openalex.org/W2156511539","https://openalex.org/W2161569931","https://openalex.org/W2162142017","https://openalex.org/W2195527239","https://openalex.org/W2217184110","https://openalex.org/W2308053466","https://openalex.org/W2319691314","https://openalex.org/W2516101459","https://openalex.org/W2548378272","https://openalex.org/W2552018811","https://openalex.org/W2589108106","https://openalex.org/W2724974634","https://openalex.org/W2754141479","https://openalex.org/W2765730264","https://openalex.org/W2790630385","https://openalex.org/W2883180045","https://openalex.org/W2886141281","https://openalex.org/W2888873474","https://openalex.org/W2889280040","https://openalex.org/W2890336669","https://openalex.org/W2890576014"],"related_works":["https://openalex.org/W2986670637","https://openalex.org/W1944945174","https://openalex.org/W3045412576","https://openalex.org/W2990357199","https://openalex.org/W2755231196","https://openalex.org/W4289981919","https://openalex.org/W4387692816","https://openalex.org/W2127938589","https://openalex.org/W3044691990","https://openalex.org/W2557492632"],"abstract_inverted_index":{"It":[0],"has":[1],"been":[2,20],"asserted":[3],"that":[4,31,219],"chronic":[5],"traumatic":[6,86],"encephalopathy":[7],"(CTE)":[8],"pathology":[9,33,169,221],"is":[10,222],"only":[11],"present":[12,36,223],"in":[13,37,65,127,137,154,224],"former":[14],"athletes":[15],"and":[16,51,105,116,130,152,159,170,186],"others":[17],"who":[18,39],"have":[19,229],"exposed":[21],"to":[22,75,98,112,205,214,228,236],"repetitive":[23,45,76],"concussions,":[24],"subconcussive":[25,234],"blows,":[26],"or":[27,233],"both.":[28],"We":[29],"hypothesized":[30],"CTE":[32,101,191,220],"would":[34],"be":[35,173],"men":[38,64],"had":[40,72,82,164,181],"no":[41,199],"known":[42,73,200,227],"history":[43,84,183,201],"of":[44,70,80,85,120,144,156,161,168,177,184,188,194,202],"neurotrauma.":[46],"Comprehensive":[47],"medical":[48],"record":[49],"reviews":[50],"health":[52],"surveys":[53],"completed":[54],"by":[55],"a":[56,83,165,182],"family":[57],"member":[58],"were":[59,150],"available":[60],"for":[61,94,100,209],"the":[62,121,142,145,162,178,195,215,237],"8":[63,122,179],"this":[66],"case":[67],"series,":[68],"none":[69],"whom":[71,81],"exposure":[74],"neurotrauma":[77,203],"but":[78],"2":[79],"brain":[87],"injury":[88],"(TBI).":[89],"Postmortem":[90],"tissue":[91],"was":[92,110],"immunostained":[93],"hyperphosphorylated":[95],"tau":[96],"(p-tau)":[97],"assess":[99],"pathology,":[102],"Braak":[103],"stage,":[104],"aging-related":[106],"p-tau.":[107],"The":[108,148],"neuropathologist":[109],"blind":[111],"age,":[113],"personal":[114],"history,":[115],"clinical":[117],"history.":[118],"Six":[119],"cases":[123,163,180,197],"(75%)":[124],"showed":[125,190],"p-tau":[126],"neurons,":[128],"astrocytes,":[129],"cell":[131],"processes":[132],"around":[133],"small":[134],"blood":[135],"vessels":[136],"an":[138],"irregular":[139],"pattern":[140,167],"at":[141],"depths":[143],"cortical":[146],"sulci.":[147],"changes":[149],"focal":[151],"limited":[153],"terms":[155],"overall":[157],"extent,":[158],"some":[160,171],"clearer":[166],"could":[172],"considered":[174],"equivocal.":[175],"Two":[176],"TBI":[185],"one":[187],"them":[189],"pathology.":[192],"Five":[193],"6":[196],"with":[198],"appeared":[204],"meet":[206],"consensus":[207],"criteria":[208],"CTE.":[210],"This":[211],"study":[212],"adds":[213],"emerging":[216],"literature":[217],"indicating":[218],"people":[225],"not":[226],"experienced":[230],"multiple":[231],"concussions":[232],"blows":[235],"head.":[238]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":19},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":15},{"year":2019,"cited_by_count":6}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2019-06-27T00:00:00"}
