{"id":"https://openalex.org/W2951789820","doi":"https://doi.org/10.1007/s10096-019-03614-y","title":"Eosinopenia as a marker of diagnosis and prognostic to distinguish bacterial from aseptic meningitis in pediatrics","display_name":"Eosinopenia as a marker of diagnosis and prognostic to distinguish bacterial from aseptic meningitis in pediatrics","publication_year":2019,"publication_date":"2019-06-22","ids":{"openalex":"https://openalex.org/W2951789820","doi":"https://doi.org/10.1007/s10096-019-03614-y","mag":"2951789820","pmid":"https://pubmed.ncbi.nlm.nih.gov/31230204"},"language":"en","primary_location":{"id":"doi:10.1007/s10096-019-03614-y","doi":"https://doi.org/10.1007/s10096-019-03614-y","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10096-019-03614-y","pdf_url":null,"source":{"id":"https://openalex.org/S130127385","display_name":"European Journal of Clinical Microbiology & Infectious Diseases","issn_l":"0934-9723","issn":["0934-9723","1435-4373"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Clinical Microbiology & Infectious Diseases","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002768566","display_name":"Agathe Debray","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210134648","display_name":"H\u00f4pital Raymond-Poincar\u00e9","ror":"https://ror.org/03pef0w96","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210134648"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Agathe Debray","raw_affiliation_strings":["Service de Maladies Infectieuses et Tropicales, Groupe Hospitalier Paris Ile de France Ouest, H\u00f4pital Universitaire Raymond-Poincar\u00e9, AP-HP, 92380, Garches, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Maladies Infectieuses et Tropicales, Groupe Hospitalier Paris Ile de France Ouest, H\u00f4pital Universitaire Raymond-Poincar\u00e9, AP-HP, 92380, Garches, France","institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210134648"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111563217","display_name":"Sylvie Nathanson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210120341","display_name":"H\u00f4pital Andr\u00e9 Mignot","ror":"https://ror.org/02r29r389","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210120341"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Sylvie Nathanson","raw_affiliation_strings":["P\u00e9diatrie g\u00e9n\u00e9rale, H\u00f4pital Andr\u00e9 Mignot, Le Chesnay, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"P\u00e9diatrie g\u00e9n\u00e9rale, H\u00f4pital Andr\u00e9 Mignot, Le Chesnay, France","institution_ids":["https://openalex.org/I4210120341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102788090","display_name":"Florence Moulin","orcid":"https://orcid.org/0000-0002-8604-2564","observed_orcids":["https://orcid.org/0000-0002-8604-2564"]},"institutions":[{"id":"https://openalex.org/I1288880153","display_name":"H\u00f4pital Necker-Enfants Malades","ror":"https://ror.org/05tr67282","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I1288880153","https://openalex.org/I4210097159","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Florence Moulin","raw_affiliation_strings":["R\u00e9animation p\u00e9diatrique, H\u00f4pital Universitaire Necker-enfants malades, AP-HP, 75015, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"R\u00e9animation p\u00e9diatrique, H\u00f4pital Universitaire Necker-enfants malades, AP-HP, 75015, Paris, France","institution_ids":["https://openalex.org/I1288880153","https://openalex.org/I4210097159"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102950615","display_name":"J. Salomon","orcid":"https://orcid.org/0000-0002-3749-4337","observed_orcids":["https://orcid.org/0000-0002-3749-4337"]},"institutions":[{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210134648","display_name":"H\u00f4pital Raymond-Poincar\u00e9","ror":"https://ror.org/03pef0w96","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210134648"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"J\u00e9rome Salomon","raw_affiliation_strings":["Service de Maladies Infectieuses et Tropicales, Groupe Hospitalier Paris Ile de France Ouest, H\u00f4pital Universitaire Raymond-Poincar\u00e9, AP-HP, 92380, Garches, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Maladies Infectieuses et Tropicales, Groupe Hospitalier Paris Ile de France Ouest, H\u00f4pital Universitaire Raymond-Poincar\u00e9, AP-HP, 92380, Garches, France","institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210134648"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089102659","display_name":"Benjamin Davido","orcid":"https://orcid.org/0000-0002-2859-8417","observed_orcids":["https://orcid.org/0000-0002-2859-8417"]},"institutions":[{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210134648","display_name":"H\u00f4pital Raymond-Poincar\u00e9","ror":"https://ror.org/03pef0w96","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210134648"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Benjamin Davido","raw_affiliation_strings":["Service de Maladies Infectieuses et Tropicales, Groupe Hospitalier Paris Ile de France Ouest, H\u00f4pital Universitaire Raymond-Poincar\u00e9, AP-HP, 92380, Garches, France. benjamin.davido@aphp.fr","Service de Maladies Infectieuses et Tropicales, Groupe Hospitalier Paris Ile de France Ouest, H\u00f4pital Universitaire Raymond-Poincar\u00e9, AP-HP, 92380, Garches, France"],"raw_orcid":"https://orcid.org/0000-0002-2859-8417","affiliations":[{"raw_affiliation_string":"Service de Maladies Infectieuses et Tropicales, Groupe Hospitalier Paris Ile de France Ouest, H\u00f4pital Universitaire Raymond-Poincar\u00e9, AP-HP, 92380, Garches, France. benjamin.davido@aphp.fr","institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210134648"]},{"raw_affiliation_string":"Service de Maladies Infectieuses et Tropicales, Groupe Hospitalier Paris Ile de France Ouest, H\u00f4pital Universitaire Raymond-Poincar\u00e9, AP-HP, 92380, Garches, France","institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210134648"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5089102659"],"corresponding_institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210134648"],"apc_list":{"value":3760,"currency":"USD","value_usd":3760},"apc_paid":null,"fwci":1.9689,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.84098019,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"38","issue":"10","first_page":"1821","last_page":"1827"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":0.9824000000953674,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":0.9824000000953674,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.010700000450015068,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13201","display_name":"Infectious Encephalopathies and Encephalitis","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/eosinopenia","display_name":"eosinopenia","score":0.9990000128746033},{"id":"https://openalex.org/keywords/bacterial-meningitis","display_name":"bacterial meningitis","score":0.9589999914169312},{"id":"https://openalex.org/keywords/aseptic-meningitis","display_name":"aseptic meningitis","score":0.9879999756813049},{"id":"https://openalex.org/keywords/viral-meningitis","display_name":"viral meningitis","score":0.8610000014305115},{"id":"https://openalex.org/keywords/pediatric-meningitis","display_name":"pediatric meningitis","score":0.9559999704360962},{"id":"https://openalex.org/keywords/eosinophil-count","display_name":"eosinophil count","score":0.8840000033378601},{"id":"https://openalex.org/keywords/diagnostic-biomarkers","display_name":"diagnostic biomarkers","score":0.8460000157356262},{"id":"https://openalex.org/keywords/low-and-middle-income-countries","display_name":"low- and middle-income countries","score":0.7760000228881836},{"id":"https://openalex.org/keywords/white-blood-cell-count","display_name":"white blood cell count","score":0.5550000071525574}],"concepts":[{"id":"https://openalex.org/C2781347865","wikidata":"https://www.wikidata.org/wiki/Q490539","display_name":"Eosinopenia","level":2,"score":0.9561676979064941},{"id":"https://openalex.org/C2781304901","wikidata":"https://www.wikidata.org/wiki/Q4804182","display_name":"Aseptic meningitis","level":3,"score":0.9302569031715393},{"id":"https://openalex.org/C2777208983","wikidata":"https://www.wikidata.org/wiki/Q3301664","display_name":"Viral meningitis","level":4,"score":0.7945765256881714},{"id":"https://openalex.org/C2781026528","wikidata":"https://www.wikidata.org/wiki/Q48143","display_name":"Meningitis","level":2,"score":0.7927148938179016},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7905100584030151},{"id":"https://openalex.org/C10936531","wikidata":"https://www.wikidata.org/wiki/Q786600","display_name":"Procalcitonin","level":3,"score":0.6409247517585754},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5136144161224365},{"id":"https://openalex.org/C190139176","wikidata":"https://www.wikidata.org/wiki/Q598976","display_name":"Medical microbiology","level":2,"score":0.48610496520996094},{"id":"https://openalex.org/C2777037409","wikidata":"https://www.wikidata.org/wiki/Q107238","display_name":"Eosinophil","level":3,"score":0.4804791510105133},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.43760427832603455},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.409153014421463},{"id":"https://openalex.org/C3018430615","wikidata":"https://www.wikidata.org/wiki/Q48143","display_name":"Bacterial meningitis","level":3,"score":0.4011264145374298},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.21009257435798645},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.10421565175056458}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004804","descriptor_name":"Eosinophils","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007970","descriptor_name":"Leukopenia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008582","descriptor_name":"Meningitis, Aseptic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D008582","descriptor_name":"Meningitis, Aseptic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016920","descriptor_name":"Meningitis, Bacterial","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D016920","descriptor_name":"Meningitis, Bacterial","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/s10096-019-03614-y","doi":"https://doi.org/10.1007/s10096-019-03614-y","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10096-019-03614-y","pdf_url":null,"source":{"id":"https://openalex.org/S130127385","display_name":"European Journal of Clinical Microbiology & Infectious Diseases","issn_l":"0934-9723","issn":["0934-9723","1435-4373"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Clinical Microbiology & Infectious Diseases","raw_type":"journal-article"},{"id":"pmid:31230204","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31230204","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology","raw_type":"Evaluation Study"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W331816002","https://openalex.org/W1507055890","https://openalex.org/W1513224400","https://openalex.org/W1566326034","https://openalex.org/W1971176804","https://openalex.org/W1977546919","https://openalex.org/W1986921709","https://openalex.org/W1988695429","https://openalex.org/W1992559836","https://openalex.org/W1996073837","https://openalex.org/W2005201152","https://openalex.org/W2012565912","https://openalex.org/W2039580290","https://openalex.org/W2052289846","https://openalex.org/W2075768713","https://openalex.org/W2079389184","https://openalex.org/W2083564871","https://openalex.org/W2093268042","https://openalex.org/W2113313324","https://openalex.org/W2113932715","https://openalex.org/W2124846113","https://openalex.org/W2150482086","https://openalex.org/W2154768189","https://openalex.org/W2161119837","https://openalex.org/W2219446765","https://openalex.org/W2411484958","https://openalex.org/W2412958935","https://openalex.org/W2416912742","https://openalex.org/W2625657664","https://openalex.org/W2753282415","https://openalex.org/W2773979395","https://openalex.org/W2896857569","https://openalex.org/W2902712312","https://openalex.org/W4230976467","https://openalex.org/W4241091316","https://openalex.org/W4300699510"],"related_works":["https://openalex.org/W2012565912","https://openalex.org/W2002830457","https://openalex.org/W3080646772","https://openalex.org/W2025850747","https://openalex.org/W4243062462","https://openalex.org/W4213331737","https://openalex.org/W2165861996","https://openalex.org/W2239306638","https://openalex.org/W2969763298","https://openalex.org/W2899012537"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":8}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-06-27T00:00:00"}