{"id":"https://openalex.org/W2951752829","doi":"https://doi.org/10.1097/01.hs9.0000564296.26534.4d","title":"PS1509 QUALITY OF LIFE IN PATIENTS WITH RRMM DURING IXA-THAL-DEX INDUCTION AND IXAZOMIB MAINTENANCE THERAPY IN COMPARISON TO THE GENERAL POPULATION","display_name":"PS1509 QUALITY OF LIFE IN PATIENTS WITH RRMM DURING IXA-THAL-DEX INDUCTION AND IXAZOMIB MAINTENANCE THERAPY IN COMPARISON TO THE GENERAL POPULATION","publication_year":2019,"publication_date":"2019-06-01","ids":{"openalex":"https://openalex.org/W2951752829","doi":"https://doi.org/10.1097/01.hs9.0000564296.26534.4d","mag":"2951752829"},"language":"en","primary_location":{"id":"doi:10.1097/01.hs9.0000564296.26534.4d","doi":"https://doi.org/10.1097/01.hs9.0000564296.26534.4d","is_oa":true,"landing_page_url":"https://doi.org/10.1097/01.hs9.0000564296.26534.4d","pdf_url":null,"source":{"id":"https://openalex.org/S4210211592","display_name":"HemaSphere","issn_l":"2572-9241","issn":["2572-9241"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-2","norway-1","oarl","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"HemaSphere","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1097/01.hs9.0000564296.26534.4d","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"H. Ludwig","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210093545","display_name":"Wilhelminen Hospital","ror":"https://ror.org/00qcsrr17","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I4210093545","https://openalex.org/I4210117134"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"H. Ludwig","raw_affiliation_strings":["Wilhelminen Cancer Research Institute, Department of Medicine I, Center for Oncology and Hematology, Wilhelminen Hospital, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wilhelminen Cancer Research Institute, Department of Medicine I, Center for Oncology and Hematology, Wilhelminen Hospital, Vienna, Austria","institution_ids":["https://openalex.org/I4210093545"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035437365","display_name":"Wolfram P\u00f6nisch","orcid":"https://orcid.org/0000-0002-9666-6274","observed_orcids":["https://orcid.org/0000-0002-9666-6274"]},"institutions":[{"id":"https://openalex.org/I926574661","display_name":"Leipzig University","ror":"https://ror.org/03s7gtk40","country_code":"DE","type":"education","lineage":["https://openalex.org/I926574661"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"W. P\u00f6nisch","raw_affiliation_strings":["Department of Hematology, University of Leipzig, Leipzig"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, University of Leipzig, Leipzig","institution_ids":["https://openalex.org/I926574661"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026611811","display_name":"Stefan Tobias Knop","orcid":"https://orcid.org/0000-0003-1276-6639","observed_orcids":["https://orcid.org/0000-0003-1276-6639"]},"institutions":[{"id":"https://openalex.org/I4210126310","display_name":"Universit\u00e4tsklinikum W\u00fcrzburg","ror":"https://ror.org/03pvr2g57","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210126310"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"S. Knop","raw_affiliation_strings":["Division of Hematology and Medical Oncology, Department of Internal Medicine II, Wuerzburg University Medical Center, Wuerzburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Medical Oncology, Department of Internal Medicine II, Wuerzburg University Medical Center, Wuerzburg, Germany","institution_ids":["https://openalex.org/I4210126310"]}]},{"author_position":"middle","author":{"id":null,"display_name":"A. Egle","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27945538","display_name":"Paracelsus Medical University","ror":"https://ror.org/03z3mg085","country_code":"AT","type":"education","lineage":["https://openalex.org/I27945538"]},{"id":"https://openalex.org/I4405255624","display_name":"Labor f\u00fcr Immunologische und Molekulare Krebsforschung","ror":"https://ror.org/037w8vx49","country_code":"AT","type":"facility","lineage":["https://openalex.org/I4210141866","https://openalex.org/I4405255624"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"A. Egle","raw_affiliation_strings":["Department of Internal Medicine III with Haematology, Medical Oncology, Hemostaseology, Infectiology and Rheumatology, Oncologic Center, Salzburg Cancer Research Institute \u2013 Laboratory for Immunological and Molecular Cancer Research (SCRI-LIMCR), Paracelsus Medical University, Salzburg, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine III with Haematology, Medical Oncology, Hemostaseology, Infectiology and Rheumatology, Oncologic Center, Salzburg Cancer Research Institute \u2013 Laboratory for Immunological and Molecular Cancer Research (SCRI-LIMCR), Paracelsus Medical University, Salzburg, Austria","institution_ids":["https://openalex.org/I27945538","https://openalex.org/I4405255624"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081805077","display_name":"Axel Hinke","orcid":"https://orcid.org/0000-0002-6037-8836","observed_orcids":["https://orcid.org/0000-0002-6037-8836"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. Hinke","raw_affiliation_strings":["CCRC Cancer Clinical Research Consulting, D\u00fcsseldorf, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CCRC Cancer Clinical Research Consulting, D\u00fcsseldorf, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011779787","display_name":"Martin Schreder","orcid":"https://orcid.org/0000-0002-1699-9715","observed_orcids":["https://orcid.org/0000-0002-1699-9715"]},"institutions":[{"id":"https://openalex.org/I4210093545","display_name":"Wilhelminen Hospital","ror":"https://ror.org/00qcsrr17","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I4210093545","https://openalex.org/I4210117134"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"M. Schreder","raw_affiliation_strings":["Wilhelminen Cancer Research Institute, Department of Medicine I, Center for Oncology and Hematology, Wilhelminen Hospital, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wilhelminen Cancer Research Institute, Department of Medicine I, Center for Oncology and Hematology, Wilhelminen Hospital, Vienna, Austria","institution_ids":["https://openalex.org/I4210093545"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040079391","display_name":"Daniel Lechner","orcid":"https://orcid.org/0000-0002-7418-7352","observed_orcids":["https://orcid.org/0000-0002-7418-7352"]},"institutions":[{"id":"https://openalex.org/I4210101126","display_name":"Hanusch Hospital","ror":"https://ror.org/0163qhr63","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I4210101126"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"D. Lechner","raw_affiliation_strings":["Third Medical Department, Hematology and Oncology, Hanusch Spital, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Third Medical Department, Hematology and Oncology, Hanusch Spital, Vienna, Austria","institution_ids":["https://openalex.org/I4210101126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090512266","display_name":"Roman H\u00e1jek","orcid":"https://orcid.org/0000-0001-6955-6267","observed_orcids":["https://orcid.org/0000-0001-6955-6267"]},"institutions":[{"id":"https://openalex.org/I4210088935","display_name":"University Hospital Ostrava","ror":"https://ror.org/00a6yph09","country_code":"CZ","type":"healthcare","lineage":["https://openalex.org/I4210088935"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"R. Hajek","raw_affiliation_strings":["Fakultn\u00ed Nemocnice Ostrava, Ostrava, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fakultn\u00ed Nemocnice Ostrava, Ostrava, Czech Republic","institution_ids":["https://openalex.org/I4210088935"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051383269","display_name":"Eberhard Gunsilius","orcid":"https://orcid.org/0000-0003-1327-2921","observed_orcids":["https://orcid.org/0000-0003-1327-2921"]},"institutions":[{"id":"https://openalex.org/I143397708","display_name":"Innsbruck Medical University","ror":"https://ror.org/03pt86f80","country_code":"AT","type":"education","lineage":["https://openalex.org/I143397708"]},{"id":"https://openalex.org/I190249584","display_name":"Universit\u00e4t Innsbruck","ror":"https://ror.org/054pv6659","country_code":"AT","type":"education","lineage":["https://openalex.org/I190249584"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"E. Gunsilius","raw_affiliation_strings":["Department of Internal Medicine V, Hematology and Oncology, Medical University Innsbruck, Innsbruck"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine V, Hematology and Oncology, Medical University Innsbruck, Innsbruck","institution_ids":["https://openalex.org/I143397708","https://openalex.org/I190249584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028771923","display_name":"Andreas Leo Petzer","orcid":"https://orcid.org/0000-0003-1595-0300","observed_orcids":["https://orcid.org/0000-0003-1595-0300"]},"institutions":[{"id":"https://openalex.org/I4210117569","display_name":"Ordensklinikum Linz Barmherzige Schwestern","ror":"https://ror.org/028rf7391","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I4210117569"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"A. Petzer","raw_affiliation_strings":["Department of Internal Medicine I, Ordensklinikum Linz - Barmherzige Schwestern, Linz, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine I, Ordensklinikum Linz - Barmherzige Schwestern, Linz, Austria","institution_ids":["https://openalex.org/I4210117569"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083484317","display_name":"Kathleen Weisel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210093545","display_name":"Wilhelminen Hospital","ror":"https://ror.org/00qcsrr17","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I4210093545","https://openalex.org/I4210117134"]},{"id":"https://openalex.org/I4210094118","display_name":"Universit\u00e4tsklinikum T\u00fcbingen","ror":"https://ror.org/00pjgxh97","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094118"]},{"id":"https://openalex.org/I8087733","display_name":"University of T\u00fcbingen","ror":"https://ror.org/03a1kwz48","country_code":"DE","type":"education","lineage":["https://openalex.org/I8087733"]}],"countries":["AT","DE"],"is_corresponding":false,"raw_author_name":"K. Weisel","raw_affiliation_strings":["Wilhelminen Cancer Research Institute, Department of Medicine I, Center for Oncology and Hematology, Wilhelminen Hospital, Vienna, Austria","Department of Internal Medicine II, Unversity Hospital Tuebingen, Tuebingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wilhelminen Cancer Research Institute, Department of Medicine I, Center for Oncology and Hematology, Wilhelminen Hospital, Vienna, Austria","institution_ids":["https://openalex.org/I4210093545"]},{"raw_affiliation_string":"Department of Internal Medicine II, Unversity Hospital Tuebingen, Tuebingen, Germany","institution_ids":["https://openalex.org/I4210094118","https://openalex.org/I8087733"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042734609","display_name":"Dietger W. Niederwieser","orcid":"https://orcid.org/0000-0002-4737-1103","observed_orcids":["https://orcid.org/0000-0002-4737-1103"]},"institutions":[{"id":"https://openalex.org/I926574661","display_name":"Leipzig University","ror":"https://ror.org/03s7gtk40","country_code":"DE","type":"education","lineage":["https://openalex.org/I926574661"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"D. Niederwieser","raw_affiliation_strings":["Department of Hematology, University of Leipzig, Leipzig"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, University of Leipzig, Leipzig","institution_ids":["https://openalex.org/I926574661"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016360607","display_name":"Hermann Einsele","orcid":"https://orcid.org/0000-0002-7680-0819","observed_orcids":["https://orcid.org/0000-0002-7680-0819"]},"institutions":[{"id":"https://openalex.org/I4210126310","display_name":"Universit\u00e4tsklinikum W\u00fcrzburg","ror":"https://ror.org/03pvr2g57","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210126310"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"H. Einsele","raw_affiliation_strings":["Division of Hematology and Medical Oncology, Department of Internal Medicine II, Wuerzburg University Medical Center, Wuerzburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Medical Oncology, Department of Internal Medicine II, Wuerzburg University Medical Center, Wuerzburg, Germany","institution_ids":["https://openalex.org/I4210126310"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071272497","display_name":"Wolfgang Willenbacher","orcid":"https://orcid.org/0000-0001-7702-1721","observed_orcids":["https://orcid.org/0000-0001-7702-1721"]},"institutions":[{"id":"https://openalex.org/I4210093545","display_name":"Wilhelminen Hospital","ror":"https://ror.org/00qcsrr17","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I4210093545","https://openalex.org/I4210117134"]},{"id":"https://openalex.org/I4210117569","display_name":"Ordensklinikum Linz Barmherzige Schwestern","ror":"https://ror.org/028rf7391","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I4210117569"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"W. Willenbacher","raw_affiliation_strings":["Department of Internal Medicine I, Ordensklinikum Linz - Barmherzige Schwestern, Linz, Austria","Wilhelminen Cancer Research Institute, Department of Medicine I, Center for Oncology and Hematology, Wilhelminen Hospital, Vienna, Austria","Oncotyrol, Center for personalized Cancer Medicine, Innsbruck"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine I, Ordensklinikum Linz - Barmherzige Schwestern, Linz, Austria","institution_ids":["https://openalex.org/I4210117569"]},{"raw_affiliation_string":"Wilhelminen Cancer Research Institute, Department of Medicine I, Center for Oncology and Hematology, Wilhelminen Hospital, Vienna, Austria","institution_ids":["https://openalex.org/I4210093545"]},{"raw_affiliation_string":"Oncotyrol, Center for personalized Cancer Medicine, Innsbruck","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050587597","display_name":"Holger F. Rumpold","orcid":"https://orcid.org/0000-0002-4118-0111","observed_orcids":["https://orcid.org/0000-0002-4118-0111"]},"institutions":[{"id":"https://openalex.org/I4210087533","display_name":"Landeskrankenhaus Feldkirch","ror":"https://ror.org/004gqpt18","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I4210087533"]},{"id":"https://openalex.org/I4210093545","display_name":"Wilhelminen Hospital","ror":"https://ror.org/00qcsrr17","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I4210093545","https://openalex.org/I4210117134"]},{"id":"https://openalex.org/I926574661","display_name":"Leipzig University","ror":"https://ror.org/03s7gtk40","country_code":"DE","type":"education","lineage":["https://openalex.org/I926574661"]}],"countries":["AT","DE"],"is_corresponding":false,"raw_author_name":"H. Rumpold","raw_affiliation_strings":["Department of Hematology, University of Leipzig, Leipzig","Wilhelminen Cancer Research Institute, Department of Medicine I, Center for Oncology and Hematology, Wilhelminen Hospital, Vienna, Austria","Department of Oncology, Hematology and Gastroenterology, Academic Teaching Hospital Feldkirch, Feldkirch, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, University of Leipzig, Leipzig","institution_ids":["https://openalex.org/I926574661"]},{"raw_affiliation_string":"Wilhelminen Cancer Research Institute, Department of Medicine I, Center for Oncology and Hematology, Wilhelminen Hospital, Vienna, Austria","institution_ids":["https://openalex.org/I4210093545"]},{"raw_affiliation_string":"Department of Oncology, Hematology and Gastroenterology, Academic Teaching Hospital Feldkirch, Feldkirch, Austria","institution_ids":["https://openalex.org/I4210087533"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112385709","display_name":"Lud\u011bk Pour","orcid":"https://orcid.org/0000-0002-6274-7009","observed_orcids":["https://orcid.org/0000-0002-6274-7009"]},"institutions":[{"id":"https://openalex.org/I4210093545","display_name":"Wilhelminen Hospital","ror":"https://ror.org/00qcsrr17","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I4210093545","https://openalex.org/I4210117134"]},{"id":"https://openalex.org/I4210102302","display_name":"University Hospital Brno","ror":"https://ror.org/00qq1fp34","country_code":"CZ","type":"healthcare","lineage":["https://openalex.org/I4210102302"]},{"id":"https://openalex.org/I4210126310","display_name":"Universit\u00e4tsklinikum W\u00fcrzburg","ror":"https://ror.org/03pvr2g57","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210126310"]}],"countries":["AT","CZ","DE"],"is_corresponding":false,"raw_author_name":"L. Pour","raw_affiliation_strings":["Division of Hematology and Medical Oncology, Department of Internal Medicine II, Wuerzburg University Medical Center, Wuerzburg, Germany","Wilhelminen Cancer Research Institute, Department of Medicine I, Center for Oncology and Hematology, Wilhelminen Hospital, Vienna, Austria","Department of Internal Medicine, Hematology and Oncology, University Hospital Brno, Brno, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Medical Oncology, Department of Internal Medicine II, Wuerzburg University Medical Center, Wuerzburg, Germany","institution_ids":["https://openalex.org/I4210126310"]},{"raw_affiliation_string":"Wilhelminen Cancer Research Institute, Department of Medicine I, Center for Oncology and Hematology, Wilhelminen Hospital, Vienna, Austria","institution_ids":["https://openalex.org/I4210093545"]},{"raw_affiliation_string":"Department of Internal Medicine, Hematology and Oncology, University Hospital Brno, Brno, Czech Republic","institution_ids":["https://openalex.org/I4210102302"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078353739","display_name":"Tom\u00e1\u0161 Jel\u00ednek","orcid":"https://orcid.org/0000-0002-5467-9253","observed_orcids":["https://orcid.org/0000-0002-5467-9253"]},"institutions":[{"id":"https://openalex.org/I4210088935","display_name":"University Hospital Ostrava","ror":"https://ror.org/00a6yph09","country_code":"CZ","type":"healthcare","lineage":["https://openalex.org/I4210088935"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"T. Jelinek","raw_affiliation_strings":["Fakultn\u00ed Nemocnice Ostrava, Ostrava, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fakultn\u00ed Nemocnice Ostrava, Ostrava, Czech Republic","institution_ids":["https://openalex.org/I4210088935"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054114426","display_name":"Karl Jochen Krenosz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27945538","display_name":"Paracelsus Medical University","ror":"https://ror.org/03z3mg085","country_code":"AT","type":"education","lineage":["https://openalex.org/I27945538"]},{"id":"https://openalex.org/I4210093545","display_name":"Wilhelminen Hospital","ror":"https://ror.org/00qcsrr17","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I4210093545","https://openalex.org/I4210117134"]},{"id":"https://openalex.org/I4210119171","display_name":"Kepler Universit\u00e4tsklinikum","ror":"https://ror.org/02h3bfj85","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I4210119171"]},{"id":"https://openalex.org/I4405255624","display_name":"Labor f\u00fcr Immunologische und Molekulare Krebsforschung","ror":"https://ror.org/037w8vx49","country_code":"AT","type":"facility","lineage":["https://openalex.org/I4210141866","https://openalex.org/I4405255624"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"K.J. Krenosz","raw_affiliation_strings":["Department of Internal Medicine III with Haematology, Medical Oncology, Hemostaseology, Infectiology and Rheumatology, Oncologic Center, Salzburg Cancer Research Institute \u2013 Laboratory for Immunological and Molecular Cancer Research (SCRI-LIMCR), Paracelsus Medical University, Salzburg, Austria","Wilhelminen Cancer Research Institute, Department of Medicine I, Center for Oncology and Hematology, Wilhelminen Hospital, Vienna, Austria","Department of Internal Medicine 3, Kepler Universitaetsklinikum GmbH, Med Campus III, Linz, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine III with Haematology, Medical Oncology, Hemostaseology, Infectiology and Rheumatology, Oncologic Center, Salzburg Cancer Research Institute \u2013 Laboratory for Immunological and Molecular Cancer Research (SCRI-LIMCR), Paracelsus Medical University, Salzburg, Austria","institution_ids":["https://openalex.org/I27945538","https://openalex.org/I4405255624"]},{"raw_affiliation_string":"Wilhelminen Cancer Research Institute, Department of Medicine I, Center for Oncology and Hematology, Wilhelminen Hospital, Vienna, Austria","institution_ids":["https://openalex.org/I4210093545"]},{"raw_affiliation_string":"Department of Internal Medicine 3, Kepler Universitaetsklinikum GmbH, Med Campus III, Linz, Austria","institution_ids":["https://openalex.org/I4210119171"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045913533","display_name":"Angela Meckl","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210093545","display_name":"Wilhelminen Hospital","ror":"https://ror.org/00qcsrr17","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I4210093545","https://openalex.org/I4210117134"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"A. Meckl","raw_affiliation_strings":["Wilhelminen Cancer Research Institute, Department of Medicine I, Center for Oncology and Hematology, Wilhelminen Hospital, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wilhelminen Cancer Research Institute, Department of Medicine I, Center for Oncology and Hematology, Wilhelminen Hospital, Vienna, Austria","institution_ids":["https://openalex.org/I4210093545"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002363544","display_name":"Sandra Nolte","orcid":"https://orcid.org/0000-0001-6185-9423","observed_orcids":["https://orcid.org/0000-0001-6185-9423"]},"institutions":[{"id":"https://openalex.org/I4210093545","display_name":"Wilhelminen Hospital","ror":"https://ror.org/00qcsrr17","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I4210093545","https://openalex.org/I4210117134"]},{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["AT","DE"],"is_corresponding":false,"raw_author_name":"S. Nolte","raw_affiliation_strings":["CCRC Cancer Clinical Research Consulting, D\u00fcsseldorf, Germany","Wilhelminen Cancer Research Institute, Department of Medicine I, Center for Oncology and Hematology, Wilhelminen Hospital, Vienna, Austria","Medical Department, Division of Psychosomatic Medicine, Charit\u00e9- Universit\u00e4tsmedizin, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CCRC Cancer Clinical Research Consulting, D\u00fcsseldorf, Germany","institution_ids":[]},{"raw_affiliation_string":"Wilhelminen Cancer Research Institute, Department of Medicine I, Center for Oncology and Hematology, Wilhelminen Hospital, Vienna, Austria","institution_ids":["https://openalex.org/I4210093545"]},{"raw_affiliation_string":"Medical Department, Division of Psychosomatic Medicine, Charit\u00e9- Universit\u00e4tsmedizin, Berlin, Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077253651","display_name":"Thomas Melchardt","orcid":"https://orcid.org/0000-0002-0122-3631","observed_orcids":["https://orcid.org/0000-0002-0122-3631"]},"institutions":[{"id":"https://openalex.org/I27945538","display_name":"Paracelsus Medical University","ror":"https://ror.org/03z3mg085","country_code":"AT","type":"education","lineage":["https://openalex.org/I27945538"]},{"id":"https://openalex.org/I4405255624","display_name":"Labor f\u00fcr Immunologische und Molekulare Krebsforschung","ror":"https://ror.org/037w8vx49","country_code":"AT","type":"facility","lineage":["https://openalex.org/I4210141866","https://openalex.org/I4405255624"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"T. Melchardt","raw_affiliation_strings":["Department of Internal Medicine III with Haematology, Medical Oncology, Hemostaseology, Infectiology and Rheumatology, Oncologic Center, Salzburg Cancer Research Institute \u2013 Laboratory for Immunological and Molecular Cancer Research (SCRI-LIMCR), Paracelsus Medical University, Salzburg, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine III with Haematology, Medical Oncology, Hemostaseology, Infectiology and Rheumatology, Oncologic Center, Salzburg Cancer Research Institute \u2013 Laboratory for Immunological and Molecular Cancer Research (SCRI-LIMCR), Paracelsus Medical University, Salzburg, Austria","institution_ids":["https://openalex.org/I27945538","https://openalex.org/I4405255624"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050976830","display_name":"R. Greil","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27945538","display_name":"Paracelsus Medical University","ror":"https://ror.org/03z3mg085","country_code":"AT","type":"education","lineage":["https://openalex.org/I27945538"]},{"id":"https://openalex.org/I4405255624","display_name":"Labor f\u00fcr Immunologische und Molekulare Krebsforschung","ror":"https://ror.org/037w8vx49","country_code":"AT","type":"facility","lineage":["https://openalex.org/I4210141866","https://openalex.org/I4405255624"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"R. Greil","raw_affiliation_strings":["Department of Internal Medicine III with Haematology, Medical Oncology, Hemostaseology, Infectiology and Rheumatology, Oncologic Center, Salzburg Cancer Research Institute \u2013 Laboratory for Immunological and Molecular Cancer Research (SCRI-LIMCR), Paracelsus Medical University, Salzburg, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine III with Haematology, Medical Oncology, Hemostaseology, Infectiology and Rheumatology, Oncologic Center, Salzburg Cancer Research Institute \u2013 Laboratory for Immunological and Molecular Cancer Research (SCRI-LIMCR), Paracelsus Medical University, Salzburg, Austria","institution_ids":["https://openalex.org/I27945538","https://openalex.org/I4405255624"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069042392","display_name":"Niklas Zojer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210093545","display_name":"Wilhelminen Hospital","ror":"https://ror.org/00qcsrr17","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I4210093545","https://openalex.org/I4210117134"]},{"id":"https://openalex.org/I4210101126","display_name":"Hanusch Hospital","ror":"https://ror.org/0163qhr63","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I4210101126"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"N. Zojer","raw_affiliation_strings":["Third Medical Department, Hematology and Oncology, Hanusch Spital, Vienna, Austria","Wilhelminen Cancer Research Institute, Department of Medicine I, Center for Oncology and Hematology, Wilhelminen Hospital, Vienna, Austria","Department of Medicine I, Center for Oncology and Hematology, Wilhelminen Hospital, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Third Medical Department, Hematology and Oncology, Hanusch Spital, Vienna, Austria","institution_ids":["https://openalex.org/I4210101126"]},{"raw_affiliation_string":"Wilhelminen Cancer Research Institute, Department of Medicine I, Center for Oncology and Hematology, Wilhelminen Hospital, Vienna, Austria","institution_ids":["https://openalex.org/I4210093545"]},{"raw_affiliation_string":"Department of Medicine I, Center for Oncology and Hematology, Wilhelminen Hospital, Vienna, Austria","institution_ids":["https://openalex.org/I4210093545"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":16,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2480,"currency":"USD","value_usd":2480},"apc_paid":{"value":2480,"currency":"USD","value_usd":2480},"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"3","issue":"S1","first_page":"695","last_page":"696"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10649","display_name":"Multiple Myeloma Research and Treatments","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10649","display_name":"Multiple Myeloma Research and Treatments","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10178","display_name":"Cancer survivorship and care","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10804","display_name":"Health Systems, Economic Evaluations, Quality of Life","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.906000018119812},{"id":"https://openalex.org/keywords/relapsed-refractory-multiple-myeloma","display_name":"relapsed/refractory multiple myeloma","score":0.996999979019165},{"id":"https://openalex.org/keywords/ixazomib","display_name":"ixazomib","score":0.9760000109672546},{"id":"https://openalex.org/keywords/thalidomide","display_name":"thalidomide","score":0.9670000076293945},{"id":"https://openalex.org/keywords/dexamethasone","display_name":"dexamethasone","score":0.9990000128746033},{"id":"https://openalex.org/keywords/patient-reported-outcomes","display_name":"patient-reported outcomes","score":0.9649999737739563},{"id":"https://openalex.org/keywords/eortc-qlq-c30","display_name":"EORTC QLQ-C30","score":0.9580000042915344},{"id":"https://openalex.org/keywords/eortc-qlq-my20","display_name":"EORTC QLQ-MY20","score":0.9990000128746033},{"id":"https://openalex.org/keywords/comparison-with-general-population","display_name":"general population comparison","score":0.7149999737739563},{"id":"https://openalex.org/keywords/physical-functioning","display_name":"physical function","score":0.5109999775886536}],"concepts":[{"id":"https://openalex.org/C2781098529","wikidata":"https://www.wikidata.org/wiki/Q20948663","display_name":"Ixazomib","level":5,"score":0.8917666077613831},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8057739734649658},{"id":"https://openalex.org/C2778283404","wikidata":"https://www.wikidata.org/wiki/Q6736822","display_name":"Maintenance therapy","level":3,"score":0.6820734739303589},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.6237102150917053},{"id":"https://openalex.org/C2779609412","wikidata":"https://www.wikidata.org/wiki/Q203174","display_name":"Thalidomide","level":3,"score":0.6221444010734558},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5184597373008728},{"id":"https://openalex.org/C2776364478","wikidata":"https://www.wikidata.org/wiki/Q467635","display_name":"Multiple myeloma","level":2,"score":0.40260037779808044},{"id":"https://openalex.org/C2776063141","wikidata":"https://www.wikidata.org/wiki/Q425681","display_name":"Lenalidomide","level":3,"score":0.39849215745925903},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.34259021282196045},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.10925409197807312},{"id":"https://openalex.org/C2780108899","wikidata":"https://www.wikidata.org/wiki/Q15366934","display_name":"Carfilzomib","level":4,"score":0.1001826822757721},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1097/01.hs9.0000564296.26534.4d","doi":"https://doi.org/10.1097/01.hs9.0000564296.26534.4d","is_oa":true,"landing_page_url":"https://doi.org/10.1097/01.hs9.0000564296.26534.4d","pdf_url":null,"source":{"id":"https://openalex.org/S4210211592","display_name":"HemaSphere","issn_l":"2572-9241","issn":["2572-9241"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-2","norway-1","oarl","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"HemaSphere","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1097/01.hs9.0000564296.26534.4d","doi":"https://doi.org/10.1097/01.hs9.0000564296.26534.4d","is_oa":true,"landing_page_url":"https://doi.org/10.1097/01.hs9.0000564296.26534.4d","pdf_url":null,"source":{"id":"https://openalex.org/S4210211592","display_name":"HemaSphere","issn_l":"2572-9241","issn":["2572-9241"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-2","norway-1","oarl","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"HemaSphere","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3036409543","https://openalex.org/W2975213507","https://openalex.org/W3094707441","https://openalex.org/W2799641062","https://openalex.org/W3089229712","https://openalex.org/W3145596383","https://openalex.org/W2602409377","https://openalex.org/W4286294615","https://openalex.org/W3165956576","https://openalex.org/W2980429921"],"abstract_inverted_index":{"Background:":[0],"Assessment":[1],"of":[2,11,14,17,23,30,48,65,86,89,172,191,315,366,385,405,417,432,438,449,490,507,517,538],"patient-reported":[3],"outcomes":[4],"(PRO)":[5],"has":[6],"become":[7],"essential":[8],"for":[9,132,144,326,341,369,396],"evaluation":[10],"the":[12,18,46,72,76,84,192,215,388,446,486,515,535,544],"burden":[13,489],"disease":[15,492],"and":[16,20,44,54,75,82,91,98,124,135,170,244,270,283,300,363,382,403,407,414,463,469,493,531],"benefits":[19],"side":[21],"effects":[22],"therapy.":[24,93],"Aims:":[25],"Here,":[26],"we":[27],"compare":[28],"parameters":[29],"QoL":[31,222,260,282,439,508],"in":[32,109,120,129,177,220,226,258,294,303,329,440,460,543],"patients":[33,95,180,228,441,478],"with":[34,39,51,229,442,503,514],"relapsed/refractory":[35],"multiple":[36],"myeloma":[37],"(RRMM)":[38],"an":[40,301,327],"age-matched":[41],"control":[42],"population":[43,194,448],"evaluate":[45],"impact":[47],"relapse":[49,501],"therapy":[50,61,102,138,174,502],"ixazomib,":[52,539],"thalidomide":[53,115],"dexamethasone":[55,125],"(IxaThalDex)":[56],"followed":[57],"by":[58,159,161,208],"ixazomib":[59,104,136,523],"maintenance":[60,92,137,320,424,524],"on":[62,100],"several":[63,221],"dimensions":[64,223,437,471,506],"QoL.":[66],"Methods:":[67],"PRO":[68],"was":[69,151,157,224,349,358,375,548],"assessed":[70,207],"using":[71],"EORTC":[73,77],"QLQ-C30":[74],"QLQ-MY20":[78],"instruments":[79],"at":[80,83,360,364,377,383,400,411,415],"baseline":[81,169],"beginning":[85],"each":[87],"cycle":[88,342,361,401,412],"induction":[90,101,173,278],"Eighty-nine":[94],"were":[96,175,206,256,310,394,472],"enrolled":[97],"started":[99],"receiving":[103],"(4":[105,139],"mg":[106,108,117,119,127,140],"[3":[107],"pts":[110,121,130],"\u226575":[111],"yrs],":[112],"d":[113],"1,8,15),":[114],"(100":[116],"[50":[118],"\u226575yrs]":[122],"daily)":[123],"(40":[126],"[20":[128],"\u226575yrs]/week)":[131],"8":[133,184,343,413],"cycles":[134,378],"d1,":[141],"8,":[142],"15)":[143],"12":[145],"months.":[146],"Score":[147],"interpretation":[148],"regarding":[149],"what":[150],"considered":[152],"a":[153,290,324,354,372,429,457],"clinically":[154,253,291,355,391],"meaningful":[155],"difference":[156,357],"guided":[158],"recommendations":[160],"Cocks":[162],"et":[163,199],"al.,":[164,200],"JCO,":[165],"2010.":[166],"Differences":[167,205],"between":[168],"end":[171,314,365,384,404,416],"analyzed":[176],"all":[178,183],"43":[179],"who":[181],"completed":[182],"cycles.":[185],"2.337":[186],"individuals":[187],"aged":[188],"60\u201369":[189],"years":[190],"general":[193,216,447],"served":[195],"as":[196,232],"controls":[197],"(Nolte":[198],"Eu":[201],"J":[202],"Cancer,":[203],"2019).":[204],"T":[209],"test.":[210],"Results:":[211],"In":[212,452],"comparison":[213],"to":[214,445,481,485,494],"population,":[217],"significant":[218,430,458],"impairment":[219,431,459],"noted":[225,311,376],"our":[227,454],"RRMM,":[230],"such":[231],"physical":[233,284,338,529],"(\u0394":[234,398,409],"\u221212.4,":[235],"p":[236,241,248,262,267,274,297,307,346],"<":[237,242,249],"0.0001),":[238,243,250],"role":[239],"(\u0394-26.6,":[240],"social":[245,370,464],"function":[246,272,285],"(\u0394-17,":[247],"while":[251,289,368,419,466,540],"no":[252,541],"relevant":[254,292,356,392],"differences":[255],"seen":[257],"global":[259,280,334],"(\u0394-6.5,":[261,266],"=":[263,268,275,298,308,347],"0.0059),":[264],"emotional":[265,467,498],"0.0038)":[269],"cognitive":[271,352],"(\u0394-5.9,":[273],"0.0014).":[276],"During":[277,319,500,522],"therapy,":[279],"health-related":[281,335],"remained":[286,421,509],"fairly":[287],"stable,":[288,510],"reduction":[293],"pain":[295,397],"(\u0394-13.2,":[296],"0.0285)":[299],"increase":[302],"polyneuropathy":[304],"(PNP)":[305],"(\u0394+23.7,":[306],"0.0002)":[309],"(baseline":[312],"vs":[313],"induction)":[316],"(figure":[317,322],"1).":[318],"treatment":[321],"1),":[323],"tendency":[325],"improvement":[328,542],"most":[330,505],"evaluated":[331],"dimensions,":[332],"like":[333],"QoL,":[336,528],"or":[337,511],"functioning":[339,371],"(significant":[340],"only":[344,473],"(\u0394+12.9,":[345],"0.0398))":[348],"observed.":[350],"For":[351],"functioning,":[353,530],"observed":[359,395],"11":[362],"maintenance,":[367],"\u0394":[373],"\u2265+10":[374],"4,":[379],"9,":[380],"10":[381],"maintenance.":[386],"Regarding":[387],"symptom":[389],"scales,":[390],"improvements":[393],"\u2265-10":[399,410],"9":[402],"maintenance)":[406],"fatigue":[408,532],"maintenance),":[418],"PNP":[420,547],"stable":[422],"during":[423],"therapy.Summary/Conclusion:":[425],"This":[426],"study":[427],"shows":[428],"several,":[433],"but":[434],"not":[435],"all,":[436],"RRMM":[443],"compared":[444],"similar":[450],"age.":[451],"particular,":[453],"data":[455],"show":[456],"physical,":[461],"role,":[462],"function,":[465],"wellbeing":[468],"other":[470],"marginally":[474],"impaired,":[475],"indicating":[476],"that":[477],"are":[479],"able":[480],"adapt":[482],"emotionally":[483],"even":[484],"very":[487],"heavy":[488],"their":[491],"maintain":[495],"almost":[496],"\u2018normal\u2019":[497],"wellbeing.":[499],"IxaThalDex,":[504],"showed":[512],"improvement,":[513],"exception":[516],"PNP,":[518],"which":[519],"worsened":[520],"significantly.":[521],"treatment,":[525],"health":[526],"related":[527],"improved":[533],"supporting":[534],"good":[536],"tolerance":[537],"presumably":[545],"thalidomide-induced":[546],"noted.":[549]},"counts_by_year":[],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2019-06-27T00:00:00"}
