{"id":"https://openalex.org/W2951573709","doi":"https://doi.org/10.1002/chin.200129046","title":"A New Ring\u2010Forming Methodology for the Synthesis of Conformationally Constrained Bioactive Molecules.","display_name":"A New Ring\u2010Forming Methodology for the Synthesis of Conformationally Constrained Bioactive Molecules.","publication_year":2001,"publication_date":"2001-07-17","ids":{"openalex":"https://openalex.org/W2951573709","doi":"https://doi.org/10.1002/chin.200129046","mag":"2951573709"},"language":"en","primary_location":{"id":"doi:10.1002/chin.200129046","doi":"https://doi.org/10.1002/chin.200129046","is_oa":false,"landing_page_url":"https://doi.org/10.1002/chin.200129046","pdf_url":null,"source":{"id":"https://openalex.org/S41354064","display_name":"ChemInform","issn_l":"0009-2975","issn":["0009-2975","0931-7597","1431-5890","1522-2667","2199-2924"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ChemInform","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067521970","display_name":"Demetris P. Papahatjis","orcid":"https://orcid.org/0000-0003-0971-6841","observed_orcids":["https://orcid.org/0000-0003-0971-6841"]},"institutions":[{"id":"https://openalex.org/I4210127711","display_name":"National Hellenic Research Foundation","ror":"https://ror.org/033m02g29","country_code":"GR","type":"funder","lineage":["https://openalex.org/I4210127711"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Demetris P. Papahatjis","raw_affiliation_strings":["Inst. Org. Pharm. Chem., Natl. Hell. Res. Found., GR-11635 Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inst. Org. Pharm. Chem., Natl. Hell. Res. Found., GR-11635 Athens, Greece","institution_ids":["https://openalex.org/I4210127711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061917163","display_name":"Spyros P. Nikas","orcid":"https://orcid.org/0000-0001-5052-5292","observed_orcids":["https://orcid.org/0000-0001-5052-5292"]},"institutions":[{"id":"https://openalex.org/I4210127711","display_name":"National Hellenic Research Foundation","ror":"https://ror.org/033m02g29","country_code":"GR","type":"funder","lineage":["https://openalex.org/I4210127711"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Spyros Nikas","raw_affiliation_strings":["Inst. Org. Pharm. Chem., Natl. Hell. Res. Found., GR-11635 Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inst. Org. Pharm. Chem., Natl. Hell. Res. Found., GR-11635 Athens, Greece","institution_ids":["https://openalex.org/I4210127711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088644120","display_name":"Andrew Tsotinis","orcid":"https://orcid.org/0000-0002-4334-4810","observed_orcids":["https://orcid.org/0000-0002-4334-4810"]},"institutions":[{"id":"https://openalex.org/I4210127711","display_name":"National Hellenic Research Foundation","ror":"https://ror.org/033m02g29","country_code":"GR","type":"funder","lineage":["https://openalex.org/I4210127711"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Andrew Tsotinis","raw_affiliation_strings":["Inst. Org. Pharm. Chem., Natl. Hell. Res. Found., GR-11635 Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inst. Org. Pharm. Chem., Natl. Hell. Res. Found., GR-11635 Athens, Greece","institution_ids":["https://openalex.org/I4210127711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006225560","display_name":"Margarita Vlachou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210127711","display_name":"National Hellenic Research Foundation","ror":"https://ror.org/033m02g29","country_code":"GR","type":"funder","lineage":["https://openalex.org/I4210127711"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Margarita Vlachou","raw_affiliation_strings":["Inst. Org. Pharm. Chem., Natl. Hell. Res. Found., GR-11635 Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inst. Org. Pharm. Chem., Natl. Hell. Res. Found., GR-11635 Athens, Greece","institution_ids":["https://openalex.org/I4210127711"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000540926","display_name":"Alexandros Makriyannis","orcid":"https://orcid.org/0000-0003-3272-3687","observed_orcids":["https://orcid.org/0000-0003-3272-3687"]},"institutions":[{"id":"https://openalex.org/I4210127711","display_name":"National Hellenic Research Foundation","ror":"https://ror.org/033m02g29","country_code":"GR","type":"funder","lineage":["https://openalex.org/I4210127711"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Alexandros Makriyannis","raw_affiliation_strings":["Inst. Org. Pharm. Chem., Natl. Hell. Res. Found., GR-11635 Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inst. Org. Pharm. Chem., Natl. Hell. Res. Found., GR-11635 Athens, Greece","institution_ids":["https://openalex.org/I4210127711"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210127711"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.27816741,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"32","issue":"29","first_page":"46","last_page":"46"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.8057000041007996,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.8057000041007996,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13859","display_name":"Organic Chemistry Synthesis Methods","score":0.051899999380111694,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10013","display_name":"Asymmetric Synthesis and Catalysis","score":0.04179999977350235,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cyclization","display_name":"cyclization","score":0.8389999866485596},{"id":"https://openalex.org/keywords/conformationally-constrained-molecules","display_name":"conformationally constrained molecules","score":0.9449999928474426},{"id":"https://openalex.org/keywords/bioactive-compounds","display_name":"bioactive compounds","score":0.8849999904632568},{"id":"https://openalex.org/keywords/heterocycle-synthesis","display_name":"heterocyclic synthesis","score":0.6320000290870667}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9868991374969482},{"id":"https://openalex.org/C2780378348","wikidata":"https://www.wikidata.org/wiki/Q25351438","display_name":"Ring (chemistry)","level":2,"score":0.7286151647567749},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.5670152902603149},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.54903244972229},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.4096720814704895},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3580912947654724},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.2054208517074585},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/chin.200129046","doi":"https://doi.org/10.1002/chin.200129046","is_oa":false,"landing_page_url":"https://doi.org/10.1002/chin.200129046","pdf_url":null,"source":{"id":"https://openalex.org/S41354064","display_name":"ChemInform","issn_l":"0009-2975","issn":["0009-2975","0931-7597","1431-5890","1522-2667","2199-2924"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ChemInform","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":1,"referenced_works":["https://openalex.org/W1556245848"],"related_works":["https://openalex.org/W2397209390","https://openalex.org/W2172073381","https://openalex.org/W4248357294","https://openalex.org/W1982559500","https://openalex.org/W2144828909","https://openalex.org/W3087101441","https://openalex.org/W2500115065","https://openalex.org/W4253684759","https://openalex.org/W2951991398","https://openalex.org/W2291685718"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2019-06-27T00:00:00"}