{"id":"https://openalex.org/W2951417516","doi":"https://doi.org/10.1002/chin.198810391","title":"ChemInform Abstract: Synthesis of the Cyclic Hexapeptide Echinocandin D. New Approaches to the Asymmetric Synthesis of \u03b2\u2010Hydroxy \u03b1\u2010Amino Acids.","display_name":"ChemInform Abstract: Synthesis of the Cyclic Hexapeptide Echinocandin D. New Approaches to the Asymmetric Synthesis of \u03b2\u2010Hydroxy \u03b1\u2010Amino Acids.","publication_year":1988,"publication_date":"1988-03-08","ids":{"openalex":"https://openalex.org/W2951417516","doi":"https://doi.org/10.1002/chin.198810391","mag":"2951417516"},"language":"en","primary_location":{"id":"doi:10.1002/chin.198810391","doi":"https://doi.org/10.1002/chin.198810391","is_oa":false,"landing_page_url":"https://doi.org/10.1002/chin.198810391","pdf_url":null,"source":{"id":"https://openalex.org/S41354064","display_name":"ChemInform","issn_l":"0009-2975","issn":["0009-2975","0931-7597","1431-5890","1522-2667","2199-2924"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ChemInform","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035782410","display_name":"David Albert Evans","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. A. EVANS","raw_affiliation_strings":["Dep. Chem., Harvard Univ., Cambridge, MA 02138, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dep. Chem., Harvard Univ., Cambridge, MA 02138, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031274832","display_name":"Ann E. Weber","orcid":"https://orcid.org/0000-0001-5388-8064","observed_orcids":["https://orcid.org/0000-0001-5388-8064"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. E. WEBER","raw_affiliation_strings":["Dep. Chem., Harvard Univ., Cambridge, MA 02138, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dep. Chem., Harvard Univ., Cambridge, MA 02138, USA","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I136199984"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.38767408,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"19","issue":"10","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.923799991607666,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.923799991607666,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10013","display_name":"Asymmetric Synthesis and Catalysis","score":0.03739999979734421,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13859","display_name":"Organic Chemistry Synthesis Methods","score":0.009600000455975533,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cyclic-hexapeptide","display_name":"cyclic hexapeptide","score":0.972000002861023},{"id":"https://openalex.org/keywords/asymmetric-synthesis","display_name":"asymmetric synthesis","score":0.6890000104904175},{"id":"https://openalex.org/keywords/beta-hydroxy-alpha-amino-acids","display_name":"\u03b2-hydroxy-\u03b1-amino acids","score":0.9459999799728394},{"id":"https://openalex.org/keywords/beta-amino-acids","display_name":"\u03b2-amino acids","score":0.9160000085830688},{"id":"https://openalex.org/keywords/threonine","display_name":"threonine","score":0.9160000085830688},{"id":"https://openalex.org/keywords/hydroxyproline","display_name":"hydroxyproline","score":0.9950000047683716},{"id":"https://openalex.org/keywords/peptide-synthesis","display_name":"peptide synthesis","score":0.531000018119812}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9723871946334839},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.6865590810775757},{"id":"https://openalex.org/C2775880066","wikidata":"https://www.wikidata.org/wiki/Q186521","display_name":"Threonine","level":4,"score":0.5999162197113037},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.43743225932121277},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.35455572605133057},{"id":"https://openalex.org/C2776414213","wikidata":"https://www.wikidata.org/wiki/Q183290","display_name":"Serine","level":3,"score":0.2953926920890808},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.2595709562301636},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1707896888256073},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0400032103061676}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/chin.198810391","doi":"https://doi.org/10.1002/chin.198810391","is_oa":false,"landing_page_url":"https://doi.org/10.1002/chin.198810391","pdf_url":null,"source":{"id":"https://openalex.org/S41354064","display_name":"ChemInform","issn_l":"0009-2975","issn":["0009-2975","0931-7597","1431-5890","1522-2667","2199-2924"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ChemInform","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":1,"referenced_works":["https://openalex.org/W1998214457"],"related_works":["https://openalex.org/W1998214457","https://openalex.org/W2514286773","https://openalex.org/W1975940001","https://openalex.org/W2953241874","https://openalex.org/W1991337015","https://openalex.org/W1971684309","https://openalex.org/W769247910","https://openalex.org/W2114990684","https://openalex.org/W4232138967","https://openalex.org/W2951515150"],"abstract_inverted_index":{"Abstract":[0],"In":[1],"addition":[2],"to":[3],"two":[4,14],"threonine":[5],"moieties":[6],"and":[7,26],"a":[8],"hydroxyproline,":[9],"the":[10],"title":[11],"compound":[12],"contains":[13],"rare":[15],"\u03b2\u2010amino":[16],"acids":[17],"which":[18],"are":[19],"synthesized":[20],"as":[21,28],"their":[22],"protected":[23],"derivatives":[24],"(VI)":[25],"(XII)":[27],"shown.":[29]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2019-06-27T00:00:00"}