{"id":"https://openalex.org/W2951001815","doi":"https://doi.org/10.1002/chin.199827122","title":"ChemInform Abstract: Potent HIV Protease Inhibitors Incorporating High\u2010Affinity P2\u2010Ligands and (R)\u2010(Hydroxyethylamino)sulfonamide Isostere.","display_name":"ChemInform Abstract: Potent HIV Protease Inhibitors Incorporating High\u2010Affinity P2\u2010Ligands and (R)\u2010(Hydroxyethylamino)sulfonamide Isostere.","publication_year":1998,"publication_date":"1998-07-07","ids":{"openalex":"https://openalex.org/W2951001815","doi":"https://doi.org/10.1002/chin.199827122","mag":"2951001815"},"language":"en","primary_location":{"id":"doi:10.1002/chin.199827122","doi":"https://doi.org/10.1002/chin.199827122","is_oa":false,"landing_page_url":"https://doi.org/10.1002/chin.199827122","pdf_url":null,"source":{"id":"https://openalex.org/S41354064","display_name":"ChemInform","issn_l":"0009-2975","issn":["0009-2975","0931-7597","1431-5890","1522-2667","2199-2924"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ChemInform","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041773055","display_name":"Arun Kumar Ghosh","orcid":"https://orcid.org/0000-0003-2472-1841","observed_orcids":["https://orcid.org/0000-0003-2472-1841"]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. K. GHOSH","raw_affiliation_strings":["Dep. Chem., Univ. Ill., Chicago, IL 60607, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dep. Chem., Univ. Ill., Chicago, IL 60607, USA","institution_ids":["https://openalex.org/I39422238"]}]},{"author_position":"last","author":{"id":null,"display_name":"ET AL. ET AL.","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"ET AL. ET AL.","raw_affiliation_strings":["Dep. Chem., Univ. Ill., Chicago, IL 60607, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dep. Chem., Univ. Ill., Chicago, IL 60607, USA","institution_ids":["https://openalex.org/I39422238"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I39422238"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.37749454,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"29","issue":"27","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hiv-protease-inhibitors","display_name":"HIV protease inhibitors","score":1.0},{"id":"https://openalex.org/keywords/p2-ligands","display_name":"P2 ligands","score":0.7730000019073486},{"id":"https://openalex.org/keywords/isosteres","display_name":"isosteres","score":0.8069999814033508},{"id":"https://openalex.org/keywords/antiretroviral-drug-design","display_name":"antiretroviral drug design","score":0.7599999904632568},{"id":"https://openalex.org/keywords/sulfonamide-derivatives","display_name":"sulfonamide derivatives","score":0.5379999876022339}],"concepts":[{"id":"https://openalex.org/C180000673","wikidata":"https://www.wikidata.org/wiki/Q899268","display_name":"Isostere","level":2,"score":0.9386879205703735},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9326504468917847},{"id":"https://openalex.org/C2781039511","wikidata":"https://www.wikidata.org/wiki/Q3208529","display_name":"Sulfonamide","level":2,"score":0.8353441953659058},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.5177604556083679},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.5021438598632812},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.456841379404068},{"id":"https://openalex.org/C2777583353","wikidata":"https://www.wikidata.org/wiki/Q410261","display_name":"HIV-1 protease","level":4,"score":0.4242521822452545},{"id":"https://openalex.org/C2776714187","wikidata":"https://www.wikidata.org/wiki/Q212410","display_name":"Protease","level":3,"score":0.39323848485946655},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2299964725971222},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.18840563297271729},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.15340590476989746},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/chin.199827122","doi":"https://doi.org/10.1002/chin.199827122","is_oa":false,"landing_page_url":"https://doi.org/10.1002/chin.199827122","pdf_url":null,"source":{"id":"https://openalex.org/S41354064","display_name":"ChemInform","issn_l":"0009-2975","issn":["0009-2975","0931-7597","1431-5890","1522-2667","2199-2924"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ChemInform","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":1,"referenced_works":["https://openalex.org/W1969406694"],"related_works":["https://openalex.org/W1969406694","https://openalex.org/W1992099478","https://openalex.org/W1994726584","https://openalex.org/W2077240119","https://openalex.org/W1998419999","https://openalex.org/W2949142017","https://openalex.org/W2952722818","https://openalex.org/W2949902362","https://openalex.org/W2950820229","https://openalex.org/W1981491253"],"abstract_inverted_index":{"Abstract":[0,25],"ChemInform":[1,24],"is":[2,42],"a":[3,11,23,35],"weekly":[4],"Abstracting":[5],"Service,":[6],"delivering":[7],"concise":[8],"information":[9],"at":[10],"glance":[12],"that":[13],"was":[14,30],"extracted":[15],"from":[16],"about":[17],"100":[18],"leading":[19],"journals.":[20],"To":[21],"access":[22],"of":[26],"an":[27],"article":[28,41],"which":[29],"published":[31],"elsewhere,":[32],"please":[33],"select":[34],"\u201cFull":[36],"Text\u201d":[37],"option.":[38,47],"The":[39],"original":[40],"trackable":[43],"via":[44],"the":[45],"\u201cReferences\u201d":[46]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2019-06-27T00:00:00"}