{"id":"https://openalex.org/W2950649199","doi":"https://doi.org/10.1111/ele.13252","title":"Nutrient stoichiometry shapes microbial coevolution","display_name":"Nutrient stoichiometry shapes microbial coevolution","publication_year":2019,"publication_date":"2019-03-29","ids":{"openalex":"https://openalex.org/W2950649199","doi":"https://doi.org/10.1111/ele.13252","mag":"2950649199","pmid":"https://pubmed.ncbi.nlm.nih.gov/30924583"},"language":"en","primary_location":{"id":"doi:10.1111/ele.13252","doi":"https://doi.org/10.1111/ele.13252","is_oa":false,"landing_page_url":"https://doi.org/10.1111/ele.13252","pdf_url":null,"source":{"id":"https://openalex.org/S80967739","display_name":"Ecology Letters","issn_l":"1461-023X","issn":["1461-023X","1461-0248"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ecology Letters","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.biorxiv.org/content/biorxiv/early/2019/02/14/183657.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027642064","display_name":"Megan L. Larsen","orcid":"https://orcid.org/0000-0002-4155-1293","observed_orcids":["https://orcid.org/0000-0002-4155-1293"]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"id":"https://openalex.org/I592451","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98","country_code":"US","type":"education","lineage":["https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Megan L. Larsen","raw_affiliation_strings":["Department of Biology, Indiana University, Bloomington, IN 47405","Department of Biology, Indiana University, Bloomington, IN, 47405 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Indiana University, Bloomington, IN 47405","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"raw_affiliation_string":"Department of Biology, Indiana University, Bloomington, IN, 47405 USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012545388","display_name":"Steven W. Wilhelm","orcid":"https://orcid.org/0000-0001-6283-8077","observed_orcids":["https://orcid.org/0000-0001-6283-8077"]},"institutions":[{"id":"https://openalex.org/I75027704","display_name":"University of Tennessee at Knoxville","ror":"https://ror.org/020f3ap87","country_code":"US","type":"education","lineage":["https://openalex.org/I75027704"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven W. Wilhelm","raw_affiliation_strings":["Department of Microbiology, University of Tennessee, Knoxville, TN 37996","Department of Microbiology, University of Tennessee, Knoxville, TN, 37996 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, University of Tennessee, Knoxville, TN 37996","institution_ids":["https://openalex.org/I75027704"]},{"raw_affiliation_string":"Department of Microbiology, University of Tennessee, Knoxville, TN, 37996 USA","institution_ids":["https://openalex.org/I75027704"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072710852","display_name":"Jay T. Lennon","orcid":"https://orcid.org/0000-0003-3126-6111","observed_orcids":["https://orcid.org/0000-0003-3126-6111","https://orcid.org/0000-0001-5451-5788"]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"id":"https://openalex.org/I592451","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98","country_code":"US","type":"education","lineage":["https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jay T. Lennon","raw_affiliation_strings":["Department of Biology, Indiana University, Bloomington, IN 47405","Department of Biology, Indiana University, Bloomington, IN, 47405 USA"],"raw_orcid":"https://orcid.org/0000-0003-3126-6111","affiliations":[{"raw_affiliation_string":"Department of Biology, Indiana University, Bloomington, IN 47405","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"raw_affiliation_string":"Department of Biology, Indiana University, Bloomington, IN, 47405 USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5072710852"],"corresponding_institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":1.6371,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.82662783,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"22","issue":"6","first_page":"1009","last_page":"1018"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11764","display_name":"Evolution and Genetic Dynamics","score":0.7954000234603882,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11764","display_name":"Evolution and Genetic Dynamics","score":0.7954000234603882,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.2013999968767166,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10482","display_name":"Mathematical and Theoretical Epidemiology and Ecology Models","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microbial-coevolution","display_name":"microbial coevolution","score":0.9559999704360962},{"id":"https://openalex.org/keywords/nutrient-stoichiometry","display_name":"nutrient stoichiometry","score":0.9909999966621399},{"id":"https://openalex.org/keywords/synechococcus","display_name":"Synechococcus","score":0.906000018119812},{"id":"https://openalex.org/keywords/lytic-phages","display_name":"lytic phages","score":0.8379999995231628},{"id":"https://openalex.org/keywords/arms-race-dynamics","display_name":"arms race dynamics","score":0.8610000014305115},{"id":"https://openalex.org/keywords/phage-resistance","display_name":"phage resistance","score":0.734000027179718},{"id":"https://openalex.org/keywords/nitrogen-limitation","display_name":"nitrogen limitation","score":0.8880000114440918},{"id":"https://openalex.org/keywords/phosphorus-limitation","display_name":"phosphorus limitation","score":1.0},{"id":"https://openalex.org/keywords/host-parasite-interactions","display_name":"host-parasite interactions","score":0.9340000152587891},{"id":"https://openalex.org/keywords/negative-frequency-dependent-selection","display_name":"negative frequency-dependent selection","score":0.7799999713897705},{"id":"https://openalex.org/keywords/eco-evolutionary-feedback","display_name":"eco-evolutionary feedback","score":0.8600000143051147},{"id":"https://openalex.org/keywords/chemostat-experiments","display_name":"chemostat experiments","score":0.6980000138282776}],"concepts":[{"id":"https://openalex.org/C33009525","wikidata":"https://www.wikidata.org/wiki/Q208841","display_name":"Coevolution","level":2,"score":0.8397486209869385},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7950820922851562},{"id":"https://openalex.org/C125111812","wikidata":"https://www.wikidata.org/wiki/Q902311","display_name":"Chemostat","level":3,"score":0.6017967462539673},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.5794698596000671},{"id":"https://openalex.org/C106358424","wikidata":"https://www.wikidata.org/wiki/Q1662346","display_name":"Infectivity","level":3,"score":0.5310626029968262},{"id":"https://openalex.org/C150108168","wikidata":"https://www.wikidata.org/wiki/Q4770895","display_name":"Antagonistic Coevolution","level":4,"score":0.5026898384094238},{"id":"https://openalex.org/C142796444","wikidata":"https://www.wikidata.org/wiki/Q181394","display_name":"Nutrient","level":2,"score":0.48522070050239563},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.4786157011985779},{"id":"https://openalex.org/C126831891","wikidata":"https://www.wikidata.org/wiki/Q221673","display_name":"Host (biology)","level":2,"score":0.47340521216392517},{"id":"https://openalex.org/C139807058","wikidata":"https://www.wikidata.org/wiki/Q352374","display_name":"Adaptation (eye)","level":2,"score":0.4461119771003723},{"id":"https://openalex.org/C73447217","wikidata":"https://www.wikidata.org/wiki/Q5333258","display_name":"Ecological stoichiometry","level":3,"score":0.445056289434433},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.24599787592887878},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.237164705991745},{"id":"https://openalex.org/C514575182","wikidata":"https://www.wikidata.org/wiki/Q228395","display_name":"Mating","level":2,"score":0.0},{"id":"https://openalex.org/C2779157341","wikidata":"https://www.wikidata.org/wiki/Q2992545","display_name":"Sexual conflict","level":3,"score":0.0},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.0},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000078622","descriptor_name":"Nutrients","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001435","descriptor_name":"Bacteriophages","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005075","descriptor_name":"Biological Evolution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006790","descriptor_name":"Host-Parasite Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D044822","descriptor_name":"Biodiversity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1111/ele.13252","doi":"https://doi.org/10.1111/ele.13252","is_oa":false,"landing_page_url":"https://doi.org/10.1111/ele.13252","pdf_url":null,"source":{"id":"https://openalex.org/S80967739","display_name":"Ecology Letters","issn_l":"1461-023X","issn":["1461-023X","1461-0248"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ecology Letters","raw_type":"journal-article"},{"id":"doi:10.1101/183657","doi":"https://doi.org/10.1101/183657","is_oa":true,"landing_page_url":"https://doi.org/10.1101/183657","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2019/02/14/183657.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmid:30924583","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30924583","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ecology letters","raw_type":"Letter"}],"best_oa_location":{"id":"doi:10.1101/183657","doi":"https://doi.org/10.1101/183657","is_oa":true,"landing_page_url":"https://doi.org/10.1101/183657","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2019/02/14/183657.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1994823736","display_name":null,"funder_award_id":"W911NF-14-1-0411","funder_id":"https://openalex.org/F4320338281","funder_display_name":"Army Research Office"},{"id":"https://openalex.org/G3424441068","display_name":null,"funder_award_id":"W911NF-14-1","funder_id":"https://openalex.org/F4320338281","funder_display_name":"Army Research Office"},{"id":"https://openalex.org/G7110252365","display_name":"Collaborative Research: Characterizing the Constraints on Virus Infection of Cyanobacteria","funder_award_id":"0851143","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G7452299184","display_name":null,"funder_award_id":"W911NF","funder_id":"https://openalex.org/F4320338281","funder_display_name":"Army Research Office"},{"id":"https://openalex.org/G911597547","display_name":"Collaborative Research: Characterizing the Constraints on Virus Infection of Cyanobacteria","funder_award_id":"0851113","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320338281","display_name":"Army Research Office","ror":"https://ror.org/05epdh915"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2950649199.pdf","grobid_xml":"https://content.openalex.org/works/W2950649199.grobid-xml"},"referenced_works_count":55,"referenced_works":["https://openalex.org/W1531651028","https://openalex.org/W1536082082","https://openalex.org/W1552724685","https://openalex.org/W1825097877","https://openalex.org/W1866364567","https://openalex.org/W1930635754","https://openalex.org/W1966572515","https://openalex.org/W1973465971","https://openalex.org/W1981069592","https://openalex.org/W1984300769","https://openalex.org/W1994995128","https://openalex.org/W2000946245","https://openalex.org/W2021958338","https://openalex.org/W2022388889","https://openalex.org/W2023201829","https://openalex.org/W2028361835","https://openalex.org/W2036713421","https://openalex.org/W2037299940","https://openalex.org/W2037820440","https://openalex.org/W2040569151","https://openalex.org/W2044333227","https://openalex.org/W2044651471","https://openalex.org/W2046736382","https://openalex.org/W2050052896","https://openalex.org/W2051196787","https://openalex.org/W2057265554","https://openalex.org/W2070190014","https://openalex.org/W2078780030","https://openalex.org/W2085703567","https://openalex.org/W2088333086","https://openalex.org/W2100728670","https://openalex.org/W2104324648","https://openalex.org/W2109112689","https://openalex.org/W2114808857","https://openalex.org/W2116935863","https://openalex.org/W2124462761","https://openalex.org/W2131891835","https://openalex.org/W2139522062","https://openalex.org/W2141135681","https://openalex.org/W2143230802","https://openalex.org/W2144195475","https://openalex.org/W2146521353","https://openalex.org/W2147648867","https://openalex.org/W2154743042","https://openalex.org/W2155002981","https://openalex.org/W2161192542","https://openalex.org/W2167987122","https://openalex.org/W2169264292","https://openalex.org/W2170568588","https://openalex.org/W2276847702","https://openalex.org/W2328095947","https://openalex.org/W2609740111","https://openalex.org/W2737230525","https://openalex.org/W2750277627","https://openalex.org/W4210796277"],"related_works":["https://openalex.org/W7095439168","https://openalex.org/W2037299940","https://openalex.org/W1536082082","https://openalex.org/W2209704384","https://openalex.org/W6948582163","https://openalex.org/W2028178639","https://openalex.org/W2925393305","https://openalex.org/W2156066664","https://openalex.org/W7099584516","https://openalex.org/W2099670135"],"abstract_inverted_index":{"Coevolution":[0],"is":[1,13,107],"a":[2,36,48],"force":[3],"contributing":[4],"to":[5],"the":[6,19,27,41,64,70,77,142],"generation":[7],"and":[8,31,69,128,144,148],"maintenance":[9],"of":[10,21,29,60,66,73,146],"biodiversity.":[11],"It":[12],"influenced":[14],"by":[15,109],"environmental":[16,147],"conditions":[17],"including":[18],"scarcity":[20],"essential":[22],"resources,":[23],"which":[24],"can":[25],"drive":[26],"evolution":[28],"defence":[30],"virulence":[32],"traits.":[33],"We":[34],"conducted":[35],"long-term":[37],"chemostat":[38],"experiment":[39],"where":[40],"marine":[42],"cyanobacterium":[43],"Synechococcus":[44],"was":[45],"challenged":[46],"with":[47,79,94],"lytic":[49],"phage":[50,91,98],"under":[51,121],"nitrogen":[52],"(N)":[53],"or":[54],"phosphorus":[55],"(P)":[56],"limitation.":[57],"This":[58],"manipulation":[59],"nutrient":[61],"stoichiometry":[62,133],"altered":[63],"stability":[65],"host-parasite":[67],"interactions":[68],"underlying":[71],"mode":[72],"coevolution.":[74],"By":[75],"assessing":[76],"infectivity":[78,99],">":[80],"18":[81],"000":[82],"pairwise":[83],"challenges,":[84],"we":[85],"documented":[86],"directional":[87],"selection":[88],"for":[89],"increased":[90],"resistance,":[92],"consistent":[93],"arms-race":[95],"dynamics":[96,143],"while":[97],"fluctuated":[100],"through":[101],"time,":[102],"as":[103],"expected":[104],"when":[105],"coevolution":[106],"driven":[108],"negative":[110],"frequency-dependent":[111],"selection.":[112],"The":[113],"resulting":[114],"infection":[115],"networks":[116],"were":[117],"50%":[118],"less":[119],"modular":[120],"N-":[122],"versus":[123],"P-limitation":[124],"reflecting":[125],"host-range":[126],"contraction":[127],"asymmetric":[129],"coevolutionary":[130],"trajectories.":[131],"Nutrient":[132],"affects":[134],"eco-evolutionary":[135],"feedbacks":[136],"in":[137],"ways":[138],"that":[139],"may":[140],"alter":[141],"functioning":[145],"host-associated":[149],"microbial":[150],"communities.":[151]},"counts_by_year":[{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2019-06-27T00:00:00"}