{"id":"https://openalex.org/W2949945241","doi":"https://doi.org/10.1111/apt.15335","title":"Baseline neutrophil\u2010to\u2010lymphocyte ratio predicts response to corticosteroids and is associated with infection and renal dysfunction in alcoholic hepatitis","display_name":"Baseline neutrophil\u2010to\u2010lymphocyte ratio predicts response to corticosteroids and is associated with infection and renal dysfunction in alcoholic hepatitis","publication_year":2019,"publication_date":"2019-07-17","ids":{"openalex":"https://openalex.org/W2949945241","doi":"https://doi.org/10.1111/apt.15335","mag":"2949945241","pmid":"https://pubmed.ncbi.nlm.nih.gov/31313853"},"language":"en","primary_location":{"id":"doi:10.1111/apt.15335","doi":"https://doi.org/10.1111/apt.15335","is_oa":false,"landing_page_url":"https://doi.org/10.1111/apt.15335","pdf_url":null,"source":{"id":"https://openalex.org/S158079644","display_name":"Alimentary Pharmacology & Therapeutics","issn_l":"0269-2813","issn":["0269-2813","1365-2036"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alimentary Pharmacology &amp; Therapeutics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://figshare.com/articles/journal_contribution/Baseline_neutrophil-to-lymphocyte_ratio_predicts_response_to_corticosteroids_and_is_associated_with_infection_and_renal_dysfunction_in_alcoholic_hepatitis/23468009","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041959522","display_name":"Ewan H. Forrest","orcid":"https://orcid.org/0000-0002-7293-2574","observed_orcids":["https://orcid.org/0000-0002-7293-2574"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Ewan H. Forrest","raw_affiliation_strings":["Glasgow, UK"],"raw_orcid":"https://orcid.org/0000-0002-7293-2574","affiliations":[{"raw_affiliation_string":"Glasgow, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053893843","display_name":"Natasha Storey","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Natasha Storey","raw_affiliation_strings":["Glasgow, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glasgow, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004305156","display_name":"Rohit Sinha","orcid":"https://orcid.org/0000-0003-4645-3243","observed_orcids":["https://orcid.org/0000-0003-4645-3243"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rohit Sinha","raw_affiliation_strings":["Edinburgh, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Edinburgh, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033038123","display_name":"Stephen R. Atkinson","orcid":"https://orcid.org/0000-0002-6910-7100","observed_orcids":["https://orcid.org/0000-0002-6910-7100"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stephen R. Atkinson","raw_affiliation_strings":["London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"London, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050333940","display_name":"Nikhil Vergis","orcid":"https://orcid.org/0000-0002-4157-6757","observed_orcids":["https://orcid.org/0000-0002-4157-6757","https://orcid.org/0000-0002-9815-0917"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nikhil Vergis","raw_affiliation_strings":["London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"London, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108270649","display_name":"Paul Richardson","orcid":"https://orcid.org/0000-0003-1488-3054","observed_orcids":["https://orcid.org/0000-0003-1488-3054"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paul Richardson","raw_affiliation_strings":["Liverpool, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Liverpool, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046286666","display_name":"Steven Masson","orcid":"https://orcid.org/0000-0003-1041-9844","observed_orcids":["https://orcid.org/0000-0003-1041-9844"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Steven Masson","raw_affiliation_strings":["Newcastle upon Tyne, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Newcastle upon Tyne, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002183213","display_name":"Stephen D. Ryder","orcid":"https://orcid.org/0000-0001-9649-4444","observed_orcids":["https://orcid.org/0000-0001-9649-4444"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stephen Ryder","raw_affiliation_strings":["Nottingham, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nottingham, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023606749","display_name":"Mark R. Thursz","orcid":"https://orcid.org/0000-0002-8218-192X","observed_orcids":["https://orcid.org/0000-0002-8218-192X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mark R. Thursz","raw_affiliation_strings":["London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"London, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021249560","display_name":"Michael Allison","orcid":"https://orcid.org/0000-0003-3677-3294","observed_orcids":["https://orcid.org/0000-0003-3677-3294"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael Allison","raw_affiliation_strings":["Cambridge, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cambridge, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008611399","display_name":"Andrew\u00a0G. Fraser","orcid":"https://orcid.org/0000-0001-9939-6014","observed_orcids":["https://orcid.org/0000-0001-9939-6014"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrew Fraser","raw_affiliation_strings":["Aberdeen, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aberdeen, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104021178","display_name":"Andrew S. Austin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrew Austin","raw_affiliation_strings":["Derby, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Derby, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070948136","display_name":"Anne McCune","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anne McCune","raw_affiliation_strings":["Bristol, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bristol, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072219713","display_name":"Ashwin Dhanda","orcid":"https://orcid.org/0000-0002-0523-0193","observed_orcids":["https://orcid.org/0000-0002-0523-0193"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ashwin Dhanda","raw_affiliation_strings":["Plymouth, UK"],"raw_orcid":"https://orcid.org/0000-0002-0523-0193","affiliations":[{"raw_affiliation_string":"Plymouth, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020766471","display_name":"Dev R Katarey","orcid":"https://orcid.org/0000-0002-6816-4963","observed_orcids":["https://orcid.org/0000-0002-6816-4963"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dev Katarey","raw_affiliation_strings":["Brighton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Brighton, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jonathan Potts","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jonathan Potts","raw_affiliation_strings":["Brighton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Brighton, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042325781","display_name":"Sumita Verma","orcid":"https://orcid.org/0000-0001-7021-8409","observed_orcids":["https://orcid.org/0000-0001-7021-8409"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sumita Verma","raw_affiliation_strings":["Brighton, UK"],"raw_orcid":"https://orcid.org/0000-0001-7021-8409","affiliations":[{"raw_affiliation_string":"Brighton, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Richard Parker","orcid":"https://orcid.org/0000-0003-4888-8670","observed_orcids":["https://orcid.org/0000-0003-4888-8670"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Richard Parker","raw_affiliation_strings":["Leeds, UK"],"raw_orcid":"https://orcid.org/0000-0003-4888-8670","affiliations":[{"raw_affiliation_string":"Leeds, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068122614","display_name":"Peter Clive Hayes","orcid":"https://orcid.org/0000-0002-9660-8322","observed_orcids":["https://orcid.org/0000-0002-9660-8322"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peter C. Hayes","raw_affiliation_strings":["Edinburgh, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Edinburgh, UK","institution_ids":[]}]},{"author_position":"last","author":{"id":null,"display_name":"the STOPAH NLR Group","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"the STOPAH NLR Group","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5041959522"],"corresponding_institution_ids":[],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":9.1767,"has_fulltext":false,"cited_by_count":89,"citation_normalized_percentile":{"value":0.98390722,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"50","issue":"4","first_page":"442","last_page":"453"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.4047999978065491,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.4047999978065491,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11355","display_name":"Inflammatory Biomarkers in Disease Prognosis","score":0.40450000762939453,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.08980000019073486,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neutrophil-to-lymphocyte-ratio","display_name":"neutrophil-to-lymphocyte ratio","score":0.9350000023841858},{"id":"https://openalex.org/keywords/severe-alcoholic-hepatitis","display_name":"severe alcoholic hepatitis","score":0.9290000200271606},{"id":"https://openalex.org/keywords/corticosteroid-response","display_name":"corticosteroid response","score":0.8560000061988831},{"id":"https://openalex.org/keywords/prednisolone","display_name":"prednisolone","score":0.9909999966621399},{"id":"https://openalex.org/keywords/acute-kidney-injury","display_name":"acute kidney injury","score":0.9390000104904175},{"id":"https://openalex.org/keywords/infection","display_name":"infection","score":0.8629999756813049},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.7850000262260437},{"id":"https://openalex.org/keywords/90-day-survival","display_name":"90-day survival","score":0.753000020980835},{"id":"https://openalex.org/keywords/inflammatory-markers","display_name":"inflammatory markers","score":0.33799999952316284}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9423279166221619},{"id":"https://openalex.org/C2776715498","wikidata":"https://www.wikidata.org/wiki/Q11426176","display_name":"Prednisolone","level":2,"score":0.8072739243507385},{"id":"https://openalex.org/C2780732942","wikidata":"https://www.wikidata.org/wiki/Q3144986","display_name":"Alcoholic hepatitis","level":4,"score":0.7860289812088013},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7840627431869507},{"id":"https://openalex.org/C2778963024","wikidata":"https://www.wikidata.org/wiki/Q17132454","display_name":"Neutrophil to lymphocyte ratio","level":3,"score":0.7193589806556702},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.6716310977935791},{"id":"https://openalex.org/C2777761686","wikidata":"https://www.wikidata.org/wiki/Q715347","display_name":"Lymphocyte","level":2,"score":0.5043090581893921},{"id":"https://openalex.org/C2776029263","wikidata":"https://www.wikidata.org/wiki/Q131742","display_name":"Hepatitis","level":2,"score":0.4638661742210388},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.4545716941356659},{"id":"https://openalex.org/C2777575235","wikidata":"https://www.wikidata.org/wiki/Q558404","display_name":"Alcoholic liver disease","level":3,"score":0.31801754236221313},{"id":"https://openalex.org/C2777214474","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Cirrhosis","level":2,"score":0.06869509816169739}],"mesh":[{"descriptor_ui":"D000305","descriptor_name":"Adrenal Cortex Hormones","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006519","descriptor_name":"Hepatitis, Alcoholic","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006519","descriptor_name":"Hepatitis, Alcoholic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006519","descriptor_name":"Hepatitis, Alcoholic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006519","descriptor_name":"Hepatitis, Alcoholic","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007239","descriptor_name":"Infections","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D007239","descriptor_name":"Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D007239","descriptor_name":"Infections","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D007239","descriptor_name":"Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D007958","descriptor_name":"Leukocyte Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D011239","descriptor_name":"Prednisolone","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054316","descriptor_name":"Biomarkers, Pharmacological","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D058186","descriptor_name":"Acute Kidney Injury","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D058186","descriptor_name":"Acute Kidney Injury","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D058186","descriptor_name":"Acute Kidney Injury","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D058186","descriptor_name":"Acute Kidney Injury","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1111/apt.15335","doi":"https://doi.org/10.1111/apt.15335","is_oa":false,"landing_page_url":"https://doi.org/10.1111/apt.15335","pdf_url":null,"source":{"id":"https://openalex.org/S158079644","display_name":"Alimentary Pharmacology & Therapeutics","issn_l":"0269-2813","issn":["0269-2813","1365-2036"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alimentary Pharmacology &amp; Therapeutics","raw_type":"journal-article"},{"id":"pmid:31313853","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31313853","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alimentary pharmacology & therapeutics","raw_type":"Journal Article"},{"id":"pmh:oai:sro.sussex.ac.uk:83789","doi":null,"is_oa":false,"landing_page_url":"http://sro.sussex.ac.uk/id/eprint/83789/3/NLR%20Alc%20Hep%20Paper%20Revised%20Manuscript%20v2.pdf","pdf_url":"http://sro.sussex.ac.uk/id/eprint/83789/3/NLR%20Alc%20Hep%20Paper%20Revised%20Manuscript%20v2.pdf","source":{"id":"https://openalex.org/S4306400129","display_name":"Sussex Research Online (University of Sussex)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I162608824","host_organization_name":"University of Sussex","host_organization_lineage":["https://openalex.org/I162608824"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:figshare.com:article/23468009","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Baseline_neutrophil-to-lymphocyte_ratio_predicts_response_to_corticosteroids_and_is_associated_with_infection_and_renal_dysfunction_in_alcoholic_hepatitis/23468009","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pure.ed.ac.uk:openaire/9da43f77-dcc4-4650-bd96-6f293da996a3","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/20.500.11820/9da43f77-dcc4-4650-bd96-6f293da996a3","pdf_url":null,"source":{"id":"https://openalex.org/S4306400321","display_name":"Edinburgh Research Explorer (University of Edinburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I98677209","host_organization_name":"University of Edinburgh","host_organization_lineage":["https://openalex.org/I98677209"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Forrest, E H, Storey, N, Sinha, R, Atkinson, S R, Vergis, N, Richardson, P, Masson, S, Ryder, S, Thursz, M R, Allison, M, Fraser, A, Austin, A, McCune, A, Dhanda, A, Katarey, D, Potts, J, Verma, S, Parker, R & Hayes, P 2019, 'Baseline neutrophil-to-lymphocyte ratio predicts response to corticosteroids and is associated with infection and renal dysfunction in alcoholic hepatitis.', Alimentary Pharmacology and Therapeutics, vol. 50, no. 4. https://doi.org/10.1111/apt.15335","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:qmro.qmul.ac.uk:123456789/64481","doi":null,"is_oa":false,"landing_page_url":"https://qmro.qmul.ac.uk/xmlui/handle/123456789/64481","pdf_url":null,"source":{"id":"https://openalex.org/S4306400530","display_name":"Queen Mary Research Online (Queen Mary University of London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I166337079","host_organization_name":"Queen Mary University of London","host_organization_lineage":["https://openalex.org/I166337079"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"pmh:oai:figshare.com:article/23468009","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Baseline_neutrophil-to-lymphocyte_ratio_predicts_response_to_corticosteroids_and_is_associated_with_infection_and_renal_dysfunction_in_alcoholic_hepatitis/23468009","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3790959518","display_name":null,"funder_award_id":"CL-2014-24-001","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G6692216761","display_name":"MICA: Minimising Mortality from Alcoholic Hepatitis","funder_award_id":"MR/R014019/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G6862517261","display_name":"Metabonomic and genetic profiling in severe alcoholic hepatitis","funder_award_id":"MR/M003132/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G8200375083","display_name":null,"funder_award_id":"ACF-2015-27-001","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"}],"funders":[{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320334661","display_name":"Health Technology Assessment Programme","ror":"https://ror.org/0187kwz08"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1485577181","https://openalex.org/W1965580254","https://openalex.org/W1973630785","https://openalex.org/W1976089489","https://openalex.org/W1985808363","https://openalex.org/W1991691835","https://openalex.org/W1997133202","https://openalex.org/W2002221121","https://openalex.org/W2018445094","https://openalex.org/W2022358118","https://openalex.org/W2044914971","https://openalex.org/W2122383784","https://openalex.org/W2124490091","https://openalex.org/W2132287184","https://openalex.org/W2161929790","https://openalex.org/W2162940124","https://openalex.org/W2182033248","https://openalex.org/W2286042547","https://openalex.org/W2417123980","https://openalex.org/W2507464717","https://openalex.org/W2514615766","https://openalex.org/W2560673122","https://openalex.org/W2561573371","https://openalex.org/W2565035141","https://openalex.org/W2565683305","https://openalex.org/W2600260459","https://openalex.org/W2768403718","https://openalex.org/W2784039673","https://openalex.org/W2791316595","https://openalex.org/W2792172944","https://openalex.org/W2794382418","https://openalex.org/W2795611455","https://openalex.org/W2800637473","https://openalex.org/W2888169974","https://openalex.org/W2888873829"],"related_works":["https://openalex.org/W4362573170","https://openalex.org/W2613565701","https://openalex.org/W2939150904","https://openalex.org/W4409988044","https://openalex.org/W2984963873","https://openalex.org/W2935906096","https://openalex.org/W4405119008","https://openalex.org/W1965057934","https://openalex.org/W2116218273","https://openalex.org/W2605397655"],"abstract_inverted_index":{"BACKGROUND:":[0],"Treating":[1],"severe":[2,34,234],"alcoholic":[3,35,111,207,235],"hepatitis":[4,208],"involves":[5],"the":[6,21,41,54,136,149,155,170,195,212],"exposure":[7],"of":[8,26,110,151,172,201],"patients":[9,32],"to":[10,15,40,66,214,243],"corticosteroids":[11,246],"for":[12,77,85,91,95,218,258],"7":[13,174],"days":[14],"assess":[16,20,67],"\"response\".":[17],"AIM:":[18],"To":[19],"prognostic":[22],"and":[23,44,71,108,184,216,220,231,260],"therapeutic":[24],"implications":[25],"baseline":[27,248],"neutrophil-to-lymphocyte":[28],"ratio":[29,73],"(NLR)":[30],"in":[31,233],"with":[33,102,132,229],"hepatitis.":[36,112,236],"METHODS:":[37],"Patients":[38],"recruited":[39],"STOPAH":[42,87],"trial":[43],"an":[45],"independent":[46],"validation":[47],"group":[48],"were":[49,75],"analysed":[50],"retrospectively.":[51],"Area":[52],"under":[53],"receiver":[55],"operating":[56],"curve":[57],"(AUC)":[58],"analysis":[59,63],"was":[60,64,83,93,100,115,130,138,157,197],"performed.":[61],"Kaplan-Meier":[62],"used":[65,76],"survival.":[68],"Log-rank":[69],"test":[70],"odds":[72],"(OR)":[74],"comparative":[78],"analysis.":[79],"RESULTS:":[80],"Baseline":[81],"NLR":[82,92,122,137,156,196,202,226,238],"available":[84],"789":[86],"patients.":[88],"The":[89,225,237,251],"AUC":[90,213],"modest":[94],"90-day":[96,221,261],"outcome":[97],"(0.660),":[98],"but":[99,128,168],"associated":[101,228],"infection,":[103],"acute":[104],"kidney":[105],"injury":[106],"(AKI)":[107],"severity":[109],"Ninety-day":[113],"survival":[114],"not":[116],"affected":[117],"by":[118],"prednisolone":[119,133],"treatment":[120,134,147],"if":[121,154,194],"<":[123],"5":[124,159],"or":[125],">":[126,198],"8":[127],"mortality":[129],"reduced":[131],"when":[135],"5-8":[139],"(21.0%":[140],"cf.":[141,161,177,187],"34.5%;":[142],"P":[143,163,179,189],"=":[144,164,180,190],"0.012).":[145],"Prednisolone":[146],"increased":[148,169],"chance":[150],"Lille":[152],"response":[153],"\u2265":[158],"(56.5%":[160],"41.1%:":[162],"0.01;":[165],"OR":[166,182,192],"1.86)":[167],"risk":[171],"day":[173],"infection":[175,232],"(17.3%":[176],"7.4%:":[178],"0.006;":[181],"2.60)":[183],"AKI":[185,230],"(20.8%":[186],"7.0%:":[188],"0.008;":[191],"3.46)":[193],"8.":[199],"Incorporation":[200],"into":[203],"a":[204,254],"modified":[205],"Glasgow":[206],"score":[209],"(mGAHS)":[210],"improved":[211],"0.783":[215],"0.739":[217],"28-day":[219],"outcome,":[222],"respectively.":[223],"CONCLUSION:":[224],"is":[227],"identifies":[239],"those":[240],"most":[241],"likely":[242],"benefit":[244],"from":[245],"at":[247],"(NLR":[249],"5-8).":[250],"mGAHS":[252],"has":[253],"good":[255],"predictive":[256],"value":[257],"28-":[259],"outcomes.":[262]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":12},{"year":2024,"cited_by_count":16},{"year":2023,"cited_by_count":16},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":22},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2019-06-27T00:00:00"}