{"id":"https://openalex.org/W2949650697","doi":"https://doi.org/10.1016/0040-4020(96)00216-5","title":"Solid-phase organic reactions: A review of the recent literature","display_name":"Solid-phase organic reactions: A review of the recent literature","publication_year":1996,"publication_date":"1996-03-01","ids":{"openalex":"https://openalex.org/W2949650697","doi":"https://doi.org/10.1016/0040-4020(96)00216-5","mag":"2949650697"},"language":"en","primary_location":{"id":"doi:10.1016/0040-4020(96)00216-5","doi":"https://doi.org/10.1016/0040-4020(96)00216-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0040-4020(96)00216-5","pdf_url":null,"source":{"id":"https://openalex.org/S205754296","display_name":"Tetrahedron","issn_l":"0040-4020","issn":["0040-4020","1464-5416"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tetrahedron","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069376664","display_name":"Pedro H. H. Hermkens","orcid":"https://orcid.org/0000-0001-7619-2297","observed_orcids":["https://orcid.org/0000-0001-7619-2297"]},"institutions":[{"id":"https://openalex.org/I4405279838","display_name":"Organon (Netherlands)","ror":"https://ror.org/02388np20","country_code":"NL","type":"company","lineage":["https://openalex.org/I4405279838"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Pedro H.H. Hermkens","raw_affiliation_strings":["Scientific Development Group, NV Organon, PO Box 20, 5340 BH Oss, The Netherlands","Scientific Development Group, Organon Labs.Ltd., Newhouse, Lanarkshire ML1 5SH, Scotland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Scientific Development Group, NV Organon, PO Box 20, 5340 BH Oss, The Netherlands","institution_ids":["https://openalex.org/I4405279838"]},{"raw_affiliation_string":"Scientific Development Group, Organon Labs.Ltd., Newhouse, Lanarkshire ML1 5SH, Scotland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057687010","display_name":"Harry C. J. Ottenheijm","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405279838","display_name":"Organon (Netherlands)","ror":"https://ror.org/02388np20","country_code":"NL","type":"company","lineage":["https://openalex.org/I4405279838"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Harry C.J. Ottenheijm","raw_affiliation_strings":["Scientific Development Group, NV Organon, PO Box 20, 5340 BH Oss, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Scientific Development Group, NV Organon, PO Box 20, 5340 BH Oss, The Netherlands","institution_ids":["https://openalex.org/I4405279838"]}]},{"author_position":"last","author":{"id":null,"display_name":"David Rees","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David Rees","raw_affiliation_strings":["Scientific Development Group, Organon Labs.Ltd., Newhouse, Lanarkshire ML1 5SH, Scotland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Scientific Development Group, Organon Labs.Ltd., Newhouse, Lanarkshire ML1 5SH, Scotland","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3680,"currency":"USD","value_usd":3680},"apc_paid":null,"fwci":70.81,"has_fulltext":false,"cited_by_count":480,"citation_normalized_percentile":{"value":0.99992353,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"52","issue":"13","first_page":"4527","last_page":"4554"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11831","display_name":"Chemical Synthesis and Reactions","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/solid-phase-organic-synthesis","display_name":"solid-phase organic synthesis","score":0.9789999723434448},{"id":"https://openalex.org/keywords/combinatorial-chemistry","display_name":"combinatorial chemistry","score":0.8870000243186951},{"id":"https://openalex.org/keywords/polymer-supported-synthesis","display_name":"polymer-supported synthesis","score":0.7990000247955322},{"id":"https://openalex.org/keywords/amide-synthesis","display_name":"amide synthesis","score":0.8759999871253967},{"id":"https://openalex.org/keywords/aromatic-substitution","display_name":"aromatic substitution","score":0.9700000286102295},{"id":"https://openalex.org/keywords/condensation","display_name":"condensation","score":0.8289999961853027},{"id":"https://openalex.org/keywords/cycloaddition","display_name":"cycloaddition","score":0.9900000095367432},{"id":"https://openalex.org/keywords/diazotization","display_name":"diazotization","score":0.9919999837875366},{"id":"https://openalex.org/keywords/enzymatic-coupling","display_name":"enzymatic coupling","score":0.9950000047683716},{"id":"https://openalex.org/keywords/grignard-reagents","display_name":"Grignard reagents","score":0.9929999709129333},{"id":"https://openalex.org/keywords/michael-addition","display_name":"Michael addition","score":0.9789999723434448},{"id":"https://openalex.org/keywords/nucleophilic-substitution","display_name":"nucleophilic substitution","score":1.0},{"id":"https://openalex.org/keywords/olefination","display_name":"olefination","score":0.9950000047683716},{"id":"https://openalex.org/keywords/oxidation","display_name":"oxidation","score":0.8560000061988831},{"id":"https://openalex.org/keywords/reduction","display_name":"reduction","score":0.6800000071525574},{"id":"https://openalex.org/keywords/immobilization","display_name":"immobilization","score":0.8830000162124634},{"id":"https://openalex.org/keywords/cleavage","display_name":"cleavage","score":0.7509999871253967},{"id":"https://openalex.org/keywords/small-molecule-synthesis","display_name":"small molecule synthesis","score":0.7770000100135803}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9122898578643799},{"id":"https://openalex.org/C2776469878","wikidata":"https://www.wikidata.org/wiki/Q2026994","display_name":"Solid-phase synthesis","level":3,"score":0.6554169654846191},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.6296222805976868},{"id":"https://openalex.org/C40875361","wikidata":"https://www.wikidata.org/wiki/Q2356542","display_name":"Reagent","level":2,"score":0.6158249974250793},{"id":"https://openalex.org/C178907741","wikidata":"https://www.wikidata.org/wiki/Q745930","display_name":"Nucleophile","level":3,"score":0.5469543933868408},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.5052254796028137},{"id":"https://openalex.org/C48424934","wikidata":"https://www.wikidata.org/wiki/Q898912","display_name":"Coupling reaction","level":3,"score":0.4807964861392975},{"id":"https://openalex.org/C535685238","wikidata":"https://www.wikidata.org/wiki/Q1153832","display_name":"Organic synthesis","level":3,"score":0.4721517562866211},{"id":"https://openalex.org/C38316802","wikidata":"https://www.wikidata.org/wiki/Q648191","display_name":"Organic reaction","level":3,"score":0.4646883010864258},{"id":"https://openalex.org/C2778439535","wikidata":"https://www.wikidata.org/wiki/Q188777","display_name":"Amide","level":2,"score":0.4502125680446625},{"id":"https://openalex.org/C135731615","wikidata":"https://www.wikidata.org/wiki/Q658656","display_name":"Nucleophilic substitution","level":2,"score":0.43886950612068176},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.43640318512916565},{"id":"https://openalex.org/C2984497647","wikidata":"https://www.wikidata.org/wiki/Q174211","display_name":"Organic molecules","level":3,"score":0.42288002371788025},{"id":"https://openalex.org/C9061509","wikidata":"https://www.wikidata.org/wiki/Q901713","display_name":"Nucleophilic aromatic substitution","level":3,"score":0.4121890664100647},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.06725969910621643},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/0040-4020(96)00216-5","doi":"https://doi.org/10.1016/0040-4020(96)00216-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0040-4020(96)00216-5","pdf_url":null,"source":{"id":"https://openalex.org/S205754296","display_name":"Tetrahedron","issn_l":"0040-4020","issn":["0040-4020","1464-5416"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tetrahedron","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":93,"referenced_works":["https://openalex.org/W94484752","https://openalex.org/W1963488776","https://openalex.org/W1964423463","https://openalex.org/W1965741502","https://openalex.org/W1966059015","https://openalex.org/W1967330835","https://openalex.org/W1968228318","https://openalex.org/W1971181177","https://openalex.org/W1972988514","https://openalex.org/W1973050612","https://openalex.org/W1973293004","https://openalex.org/W1974931649","https://openalex.org/W1979102890","https://openalex.org/W1980358960","https://openalex.org/W1982548738","https://openalex.org/W1985819890","https://openalex.org/W1986170186","https://openalex.org/W1991961079","https://openalex.org/W1992967180","https://openalex.org/W1998349044","https://openalex.org/W1998682872","https://openalex.org/W2004598036","https://openalex.org/W2006935178","https://openalex.org/W2012588456","https://openalex.org/W2013862269","https://openalex.org/W2014280021","https://openalex.org/W2019598393","https://openalex.org/W2021302213","https://openalex.org/W2021652524","https://openalex.org/W2022595062","https://openalex.org/W2024075822","https://openalex.org/W2025818252","https://openalex.org/W2026895094","https://openalex.org/W2027195765","https://openalex.org/W2027847800","https://openalex.org/W2028644986","https://openalex.org/W2028983179","https://openalex.org/W2030863551","https://openalex.org/W2031415145","https://openalex.org/W2031773242","https://openalex.org/W2038260046","https://openalex.org/W2038743754","https://openalex.org/W2039328214","https://openalex.org/W2042952330","https://openalex.org/W2043924333","https://openalex.org/W2045972197","https://openalex.org/W2047566559","https://openalex.org/W2050554743","https://openalex.org/W2053314863","https://openalex.org/W2053508373","https://openalex.org/W2054682197","https://openalex.org/W2056419926","https://openalex.org/W2056875907","https://openalex.org/W2057140048","https://openalex.org/W2058289726","https://openalex.org/W2062843509","https://openalex.org/W2064117551","https://openalex.org/W2065024055","https://openalex.org/W2067597300","https://openalex.org/W2068896180","https://openalex.org/W2072719700","https://openalex.org/W2074995086","https://openalex.org/W2075895271","https://openalex.org/W2086785404","https://openalex.org/W2095501207","https://openalex.org/W2136870717","https://openalex.org/W2139609076","https://openalex.org/W2145525736","https://openalex.org/W2162250498","https://openalex.org/W2162303607","https://openalex.org/W2320556745","https://openalex.org/W2411436508","https://openalex.org/W2949217621","https://openalex.org/W2949579733","https://openalex.org/W2949643240","https://openalex.org/W2949655188","https://openalex.org/W2949678656","https://openalex.org/W2950091112","https://openalex.org/W2950216827","https://openalex.org/W2950339595","https://openalex.org/W2950949227","https://openalex.org/W2951211136","https://openalex.org/W2952332140","https://openalex.org/W2952489791","https://openalex.org/W2952593233","https://openalex.org/W2952635130","https://openalex.org/W2953064758","https://openalex.org/W2953282561","https://openalex.org/W2953283367","https://openalex.org/W2955563265","https://openalex.org/W3101180015","https://openalex.org/W4242462517","https://openalex.org/W4254022846"],"related_works":["https://openalex.org/W2171386360","https://openalex.org/W2914210023","https://openalex.org/W2072719700","https://openalex.org/W618637240","https://openalex.org/W2074197144","https://openalex.org/W2949332182","https://openalex.org/W4230632487","https://openalex.org/W4249461528","https://openalex.org/W2412787859","https://openalex.org/W4319308389"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":7}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2019-06-27T00:00:00"}