{"id":"https://openalex.org/W2948587646","doi":"https://doi.org/10.1016/j.ijbiomac.2019.06.006","title":"Phage display antibody libraries: A robust approach for generation of recombinant human monoclonal antibodies","display_name":"Phage display antibody libraries: A robust approach for generation of recombinant human monoclonal antibodies","publication_year":2019,"publication_date":"2019-06-03","ids":{"openalex":"https://openalex.org/W2948587646","doi":"https://doi.org/10.1016/j.ijbiomac.2019.06.006","mag":"2948587646","pmid":"https://pubmed.ncbi.nlm.nih.gov/31170490"},"language":"en","primary_location":{"id":"doi:10.1016/j.ijbiomac.2019.06.006","doi":"https://doi.org/10.1016/j.ijbiomac.2019.06.006","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ijbiomac.2019.06.006","pdf_url":null,"source":{"id":"https://openalex.org/S83853393","display_name":"International Journal of Biological Macromolecules","issn_l":"0141-8130","issn":["0141-8130","1879-0003"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Biological Macromolecules","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108054380","display_name":"Rajesh Kumar","orcid":"https://orcid.org/0000-0002-6744-0241","observed_orcids":["https://orcid.org/0000-0002-6744-0241"]},"institutions":[{"id":"https://openalex.org/I2801880299","display_name":"Translational Health Science and Technology Institute","ror":"https://ror.org/01qjqvr92","country_code":"IN","type":"government","lineage":["https://openalex.org/I2799351866","https://openalex.org/I2801880299","https://openalex.org/I4210134808"]},{"id":"https://openalex.org/I63739035","display_name":"All India Institute of Medical Sciences","ror":"https://ror.org/02dwcqs71","country_code":"IN","type":"education","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210148677","https://openalex.org/I63739035"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Rajesh Kumar","raw_affiliation_strings":["Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India; Translational Health Science & Technology Institute, NCR Biotech Science Cluster, Faridabad, Haryana 121001, India. Electronic address: rajesh@thsti.res.in","Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India","Translational Health Science & Technology Institute, NCR Biotech Science Cluster, Faridabad, Haryana 121001, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India; Translational Health Science & Technology Institute, NCR Biotech Science Cluster, Faridabad, Haryana 121001, India. Electronic address: rajesh@thsti.res.in","institution_ids":["https://openalex.org/I2801880299","https://openalex.org/I63739035"]},{"raw_affiliation_string":"Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India","institution_ids":["https://openalex.org/I63739035"]},{"raw_affiliation_string":"Translational Health Science & Technology Institute, NCR Biotech Science Cluster, Faridabad, Haryana 121001, India","institution_ids":["https://openalex.org/I2801880299"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110446803","display_name":"Hilal Ahmed Parray","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63739035","display_name":"All India Institute of Medical Sciences","ror":"https://ror.org/02dwcqs71","country_code":"IN","type":"education","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210148677","https://openalex.org/I63739035"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Hilal Ahmed Parray","raw_affiliation_strings":["Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India","institution_ids":["https://openalex.org/I63739035"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025774887","display_name":"Tripti Shrivastava","orcid":"https://orcid.org/0000-0001-6942-1274","observed_orcids":["https://orcid.org/0000-0001-6942-1274"]},"institutions":[{"id":"https://openalex.org/I2801880299","display_name":"Translational Health Science and Technology Institute","ror":"https://ror.org/01qjqvr92","country_code":"IN","type":"government","lineage":["https://openalex.org/I2799351866","https://openalex.org/I2801880299","https://openalex.org/I4210134808"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Tripti Shrivastava","raw_affiliation_strings":["Translational Health Science & Technology Institute, NCR Biotech Science Cluster, Faridabad, Haryana 121001, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Translational Health Science & Technology Institute, NCR Biotech Science Cluster, Faridabad, Haryana 121001, India","institution_ids":["https://openalex.org/I2801880299"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069308603","display_name":"Subrata Sinha","orcid":"https://orcid.org/0000-0002-2461-0415","observed_orcids":["https://orcid.org/0000-0002-2461-0415","https://orcid.org/0000-0002-2063-257X"]},"institutions":[{"id":"https://openalex.org/I63739035","display_name":"All India Institute of Medical Sciences","ror":"https://ror.org/02dwcqs71","country_code":"IN","type":"education","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210148677","https://openalex.org/I63739035"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Subrata Sinha","raw_affiliation_strings":["Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India","institution_ids":["https://openalex.org/I63739035"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049295965","display_name":"Kalpana Luthra","orcid":"https://orcid.org/0000-0002-7801-2867","observed_orcids":["https://orcid.org/0000-0002-7801-2867"]},"institutions":[{"id":"https://openalex.org/I63739035","display_name":"All India Institute of Medical Sciences","ror":"https://ror.org/02dwcqs71","country_code":"IN","type":"education","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210148677","https://openalex.org/I63739035"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Kalpana Luthra","raw_affiliation_strings":["Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India. Electronic address: kalpanaluthra@gmail.com","Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India. Electronic address: kalpanaluthra@gmail.com","institution_ids":["https://openalex.org/I63739035"]},{"raw_affiliation_string":"Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India","institution_ids":["https://openalex.org/I63739035"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5049295965","https://openalex.org/A5108054380"],"corresponding_institution_ids":["https://openalex.org/I2801880299","https://openalex.org/I63739035"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.9994,"has_fulltext":false,"cited_by_count":112,"citation_normalized_percentile":{"value":0.73027211,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"135","issue":null,"first_page":"907","last_page":"918"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11124","display_name":"Protein purification and stability","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/phage-display","display_name":"phage display","score":0.9850000143051147},{"id":"https://openalex.org/keywords/antibody-libraries","display_name":"antibody libraries","score":0.7710000276565552},{"id":"https://openalex.org/keywords/recombinant-monoclonal-antibodies","display_name":"recombinant monoclonal antibodies","score":0.8399999737739563},{"id":"https://openalex.org/keywords/human-monoclonal-antibodies","display_name":"human monoclonal antibodies","score":0.8399999737739563},{"id":"https://openalex.org/keywords/antibody-isolation","display_name":"antibody isolation","score":0.7689999938011169},{"id":"https://openalex.org/keywords/therapeutic-antibodies","display_name":"therapeutic antibodies","score":0.7900000214576721},{"id":"https://openalex.org/keywords/antibody-repertoire","display_name":"antibody repertoire","score":0.35199999809265137}],"concepts":[{"id":"https://openalex.org/C186268636","wikidata":"https://www.wikidata.org/wiki/Q896217","display_name":"Phage display","level":3,"score":0.8704515695571899},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.8612161874771118},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.6755131483078003},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.5718889236450195},{"id":"https://openalex.org/C2778502174","wikidata":"https://www.wikidata.org/wiki/Q978273","display_name":"Hybridoma technology","level":4,"score":0.5353128910064697},{"id":"https://openalex.org/C3020495827","wikidata":"https://www.wikidata.org/wiki/Q426141","display_name":"Bispecific antibody","level":4,"score":0.5330482721328735},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.49162107706069946},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.44645583629608154},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.44186562299728394},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4282292127609253},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.37743133306503296},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3286527395248413},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08389967679977417},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D061505","descriptor_name":"Cell Surface Display Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.ijbiomac.2019.06.006","doi":"https://doi.org/10.1016/j.ijbiomac.2019.06.006","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ijbiomac.2019.06.006","pdf_url":null,"source":{"id":"https://openalex.org/S83853393","display_name":"International Journal of Biological Macromolecules","issn_l":"0141-8130","issn":["0141-8130","1879-0003"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Biological Macromolecules","raw_type":"journal-article"},{"id":"pmid:31170490","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31170490","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of biological macromolecules","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8560000061988831,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320316895","display_name":"Aeronautics Research Mission Directorate","ror":null},{"id":"https://openalex.org/F4320324337","display_name":"All-India Institute of Medical Sciences","ror":"https://ror.org/02dwcqs71"},{"id":"https://openalex.org/F4320332162","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":139,"referenced_works":["https://openalex.org/W10010671","https://openalex.org/W206701898","https://openalex.org/W630338634","https://openalex.org/W1522380633","https://openalex.org/W1523729788","https://openalex.org/W1531785323","https://openalex.org/W1546210634","https://openalex.org/W1549258100","https://openalex.org/W1573380426","https://openalex.org/W1584436890","https://openalex.org/W1862569453","https://openalex.org/W1966763137","https://openalex.org/W1968704981","https://openalex.org/W1972018125","https://openalex.org/W1972242350","https://openalex.org/W1973123797","https://openalex.org/W1975213486","https://openalex.org/W1979552897","https://openalex.org/W1979886683","https://openalex.org/W1981955271","https://openalex.org/W1983451228","https://openalex.org/W1989544708","https://openalex.org/W1989672802","https://openalex.org/W1992843439","https://openalex.org/W1994323576","https://openalex.org/W1996366496","https://openalex.org/W1996820981","https://openalex.org/W2001875799","https://openalex.org/W2002632348","https://openalex.org/W2006174330","https://openalex.org/W2009545641","https://openalex.org/W2009735641","https://openalex.org/W2011261569","https://openalex.org/W2020092155","https://openalex.org/W2021164895","https://openalex.org/W2021192389","https://openalex.org/W2021256658","https://openalex.org/W2022228265","https://openalex.org/W2023981380","https://openalex.org/W2025208931","https://openalex.org/W2031154947","https://openalex.org/W2043330120","https://openalex.org/W2043381970","https://openalex.org/W2045482566","https://openalex.org/W2045827741","https://openalex.org/W2052360985","https://openalex.org/W2054592480","https://openalex.org/W2057338945","https://openalex.org/W2057782477","https://openalex.org/W2058268622","https://openalex.org/W2059140632","https://openalex.org/W2060455109","https://openalex.org/W2061154067","https://openalex.org/W2065303540","https://openalex.org/W2066522660","https://openalex.org/W2070360032","https://openalex.org/W2072576950","https://openalex.org/W2074022830","https://openalex.org/W2074560222","https://openalex.org/W2076751523","https://openalex.org/W2083153683","https://openalex.org/W2089861713","https://openalex.org/W2090475692","https://openalex.org/W2091830592","https://openalex.org/W2094656087","https://openalex.org/W2098119218","https://openalex.org/W2104290364","https://openalex.org/W2105480051","https://openalex.org/W2106091801","https://openalex.org/W2106949912","https://openalex.org/W2109844644","https://openalex.org/W2122134070","https://openalex.org/W2123562124","https://openalex.org/W2124559972","https://openalex.org/W2125542251","https://openalex.org/W2129978599","https://openalex.org/W2133250226","https://openalex.org/W2137663279","https://openalex.org/W2138461857","https://openalex.org/W2142840682","https://openalex.org/W2145186082","https://openalex.org/W2148043455","https://openalex.org/W2148044509","https://openalex.org/W2154216619","https://openalex.org/W2159725525","https://openalex.org/W2160813629","https://openalex.org/W2166930862","https://openalex.org/W2169717072","https://openalex.org/W2169840840","https://openalex.org/W2170556348","https://openalex.org/W2171569403","https://openalex.org/W2175687390","https://openalex.org/W2271663961","https://openalex.org/W2273249389","https://openalex.org/W2400372532","https://openalex.org/W2415469056","https://openalex.org/W2474760928","https://openalex.org/W2480645939","https://openalex.org/W2509085740","https://openalex.org/W2552430370","https://openalex.org/W2590315157","https://openalex.org/W2596908440","https://openalex.org/W2597045666","https://openalex.org/W2597432462","https://openalex.org/W2599214495","https://openalex.org/W2604025583","https://openalex.org/W2617639998","https://openalex.org/W2626236550","https://openalex.org/W2725845241","https://openalex.org/W2740919839","https://openalex.org/W2749398329","https://openalex.org/W2761940121","https://openalex.org/W2767358466","https://openalex.org/W2767539007","https://openalex.org/W2767993154","https://openalex.org/W2768042095","https://openalex.org/W2768064384","https://openalex.org/W2769688696","https://openalex.org/W2782985061","https://openalex.org/W2784605149","https://openalex.org/W2789977408","https://openalex.org/W2790848357","https://openalex.org/W2790876771","https://openalex.org/W2793844201","https://openalex.org/W2809145153","https://openalex.org/W2889284966","https://openalex.org/W2891666054","https://openalex.org/W2895982607","https://openalex.org/W2898101403","https://openalex.org/W2901838972","https://openalex.org/W2911397938","https://openalex.org/W2917928050","https://openalex.org/W2947780489","https://openalex.org/W2949947966","https://openalex.org/W2981273636","https://openalex.org/W4211045835","https://openalex.org/W4236501910","https://openalex.org/W4365787420","https://openalex.org/W6716231544"],"related_works":["https://openalex.org/W3044690826","https://openalex.org/W4416095104","https://openalex.org/W4377940889","https://openalex.org/W2327986674","https://openalex.org/W4407258125","https://openalex.org/W3177647296","https://openalex.org/W4401148469","https://openalex.org/W2795803014","https://openalex.org/W2078138780","https://openalex.org/W2408489583"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":22},{"year":2023,"cited_by_count":23},{"year":2022,"cited_by_count":24},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":4}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2019-06-14T00:00:00"}