{"id":"https://openalex.org/W2948410175","doi":"https://doi.org/10.1186/s41232-019-0101-5","title":"The role of interleukin-1 in general pathology","display_name":"The role of interleukin-1 in general pathology","publication_year":2019,"publication_date":"2019-06-05","ids":{"openalex":"https://openalex.org/W2948410175","doi":"https://doi.org/10.1186/s41232-019-0101-5","mag":"2948410175","pmid":"https://pubmed.ncbi.nlm.nih.gov/31182982","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6551897"},"language":"en","primary_location":{"id":"doi:10.1186/s41232-019-0101-5","doi":"https://doi.org/10.1186/s41232-019-0101-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s41232-019-0101-5","pdf_url":"https://inflammregen.biomedcentral.com/track/pdf/10.1186/s41232-019-0101-5","source":{"id":"https://openalex.org/S143716263","display_name":"Inflammation and Regeneration","issn_l":"1346-8022","issn":["1346-8022","1880-5795","1880-8190","1880-9693"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","norway-1","oarl","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Inflammation and Regeneration","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://inflammregen.biomedcentral.com/track/pdf/10.1186/s41232-019-0101-5","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084390582","display_name":"Naoe Kaneko","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I43545212","display_name":"Ehime University","ror":"https://ror.org/017hkng22","country_code":"JP","type":"education","lineage":["https://openalex.org/I43545212"]},{"id":"https://openalex.org/I4405287542","display_name":"Proteo-Science Center, Ehime University","ror":"https://ror.org/05ffb9p90","country_code":"JP","type":"facility","lineage":["https://openalex.org/I43545212","https://openalex.org/I4405287542"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Naoe Kaneko","raw_affiliation_strings":["Department of Pathology, Ehime University Graduate School of Medicine and Proteo-Science Center, Shitsukawa 454, Toon, Ehime, 791-0295, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Ehime University Graduate School of Medicine and Proteo-Science Center, Shitsukawa 454, Toon, Ehime, 791-0295, Japan","institution_ids":["https://openalex.org/I43545212","https://openalex.org/I4405287542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051602851","display_name":"Mie Kurata","orcid":"https://orcid.org/0000-0001-6596-2436","observed_orcids":["https://orcid.org/0000-0001-6596-2436"]},"institutions":[{"id":"https://openalex.org/I43545212","display_name":"Ehime University","ror":"https://ror.org/017hkng22","country_code":"JP","type":"education","lineage":["https://openalex.org/I43545212"]},{"id":"https://openalex.org/I4405287542","display_name":"Proteo-Science Center, Ehime University","ror":"https://ror.org/05ffb9p90","country_code":"JP","type":"facility","lineage":["https://openalex.org/I43545212","https://openalex.org/I4405287542"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mie Kurata","raw_affiliation_strings":["Department of Pathology, Ehime University Graduate School of Medicine and Proteo-Science Center, Shitsukawa 454, Toon, Ehime, 791-0295, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Ehime University Graduate School of Medicine and Proteo-Science Center, Shitsukawa 454, Toon, Ehime, 791-0295, Japan","institution_ids":["https://openalex.org/I43545212","https://openalex.org/I4405287542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111841510","display_name":"Toshihiro Yamamoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I43545212","display_name":"Ehime University","ror":"https://ror.org/017hkng22","country_code":"JP","type":"education","lineage":["https://openalex.org/I43545212"]},{"id":"https://openalex.org/I4405287542","display_name":"Proteo-Science Center, Ehime University","ror":"https://ror.org/05ffb9p90","country_code":"JP","type":"facility","lineage":["https://openalex.org/I43545212","https://openalex.org/I4405287542"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshihiro Yamamoto","raw_affiliation_strings":["Department of Pathology, Ehime University Graduate School of Medicine and Proteo-Science Center, Shitsukawa 454, Toon, Ehime, 791-0295, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Ehime University Graduate School of Medicine and Proteo-Science Center, Shitsukawa 454, Toon, Ehime, 791-0295, Japan","institution_ids":["https://openalex.org/I43545212","https://openalex.org/I4405287542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019474102","display_name":"Shinnosuke Morikawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I43545212","display_name":"Ehime University","ror":"https://ror.org/017hkng22","country_code":"JP","type":"education","lineage":["https://openalex.org/I43545212"]},{"id":"https://openalex.org/I4405287542","display_name":"Proteo-Science Center, Ehime University","ror":"https://ror.org/05ffb9p90","country_code":"JP","type":"facility","lineage":["https://openalex.org/I43545212","https://openalex.org/I4405287542"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinnosuke Morikawa","raw_affiliation_strings":["Department of Pathology, Ehime University Graduate School of Medicine and Proteo-Science Center, Shitsukawa 454, Toon, Ehime, 791-0295, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Ehime University Graduate School of Medicine and Proteo-Science Center, Shitsukawa 454, Toon, Ehime, 791-0295, Japan","institution_ids":["https://openalex.org/I43545212","https://openalex.org/I4405287542"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061727322","display_name":"Junya Masumoto","orcid":"https://orcid.org/0000-0003-0847-0456","observed_orcids":["https://orcid.org/0000-0003-0847-0456"]},"institutions":[{"id":"https://openalex.org/I43545212","display_name":"Ehime University","ror":"https://ror.org/017hkng22","country_code":"JP","type":"education","lineage":["https://openalex.org/I43545212"]},{"id":"https://openalex.org/I4405287542","display_name":"Proteo-Science Center, Ehime University","ror":"https://ror.org/05ffb9p90","country_code":"JP","type":"facility","lineage":["https://openalex.org/I43545212","https://openalex.org/I4405287542"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Junya Masumoto","raw_affiliation_strings":["Department of Pathology, Ehime University Graduate School of Medicine and Proteo-Science Center, Shitsukawa 454, Toon, Ehime, 791-0295, Japan"],"raw_orcid":"https://orcid.org/0000-0003-0847-0456","affiliations":[{"raw_affiliation_string":"Department of Pathology, Ehime University Graduate School of Medicine and Proteo-Science Center, Shitsukawa 454, Toon, Ehime, 791-0295, Japan","institution_ids":["https://openalex.org/I43545212","https://openalex.org/I4405287542"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5061727322"],"corresponding_institution_ids":["https://openalex.org/I43545212","https://openalex.org/I4405287542"],"apc_list":{"value":993,"currency":"USD","value_usd":993},"apc_paid":{"value":993,"currency":"USD","value_usd":993},"fwci":4.4329,"has_fulltext":true,"cited_by_count":642,"citation_normalized_percentile":{"value":0.97111701,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"39","issue":"1","first_page":"12","last_page":"12"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11078","display_name":"Inflammasome and immune disorders","score":0.5259000062942505,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11078","display_name":"Inflammasome and immune disorders","score":0.5259000062942505,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11503","display_name":"Cytokine Signaling Pathways and Interactions","score":0.22089999914169312,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.17759999632835388,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interleukin-1","display_name":"interleukin-1","score":0.9990000128746033},{"id":"https://openalex.org/keywords/interleukin-1-family","display_name":"interleukin-1 family","score":0.8759999871253967},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.9520000219345093},{"id":"https://openalex.org/keywords/innate-immunity","display_name":"innate immunity","score":0.9309999942779541},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.7059999704360962},{"id":"https://openalex.org/keywords/general-pathology","display_name":"general pathology","score":0.7300000190734863},{"id":"https://openalex.org/keywords/molecular-pathogenesis","display_name":"molecular pathogenesis","score":0.5680000185966492}],"concepts":[{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.6040018796920776},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5947349071502686},{"id":"https://openalex.org/C74172505","wikidata":"https://www.wikidata.org/wiki/Q194908","display_name":"Interleukin","level":3,"score":0.5287047624588013},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5227963328361511},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.47605085372924805},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.47080719470977783},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4673597812652588},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.4480578601360321},{"id":"https://openalex.org/C3020625565","wikidata":"https://www.wikidata.org/wiki/Q194908","display_name":"Interleukin 1\u03b2","level":4,"score":0.43398287892341614},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3900723457336426},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.28689274191856384},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.23859506845474243},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.22638267278671265}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1186/s41232-019-0101-5","doi":"https://doi.org/10.1186/s41232-019-0101-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s41232-019-0101-5","pdf_url":"https://inflammregen.biomedcentral.com/track/pdf/10.1186/s41232-019-0101-5","source":{"id":"https://openalex.org/S143716263","display_name":"Inflammation and Regeneration","issn_l":"1346-8022","issn":["1346-8022","1880-5795","1880-8190","1880-9693"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","norway-1","oarl","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Inflammation and Regeneration","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6551897","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6551897","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Inflamm Regen","raw_type":"Text"},{"id":"pmid:31182982","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31182982","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Inflammation and regeneration","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:c80d78ccb25647a38d3e6b53951803df","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/c80d78ccb25647a38d3e6b53951803df","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Inflammation and Regeneration, Vol 39, Iss 1, Pp 1-16 (2019)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s41232-019-0101-5","doi":"https://doi.org/10.1186/s41232-019-0101-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s41232-019-0101-5","pdf_url":"https://inflammregen.biomedcentral.com/track/pdf/10.1186/s41232-019-0101-5","source":{"id":"https://openalex.org/S143716263","display_name":"Inflammation and Regeneration","issn_l":"1346-8022","issn":["1346-8022","1880-5795","1880-8190","1880-9693"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","norway-1","oarl","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Inflammation and Regeneration","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3471729920","display_name":"Acceleration of the definition of \"inflammasome disease\" based on molecular mechanism of diseases","funder_award_id":"17K19685","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G5792343007","display_name":"NLRP3\u30a4\u30f3\u30d5\u30e9\u30de\u30bd\u30fc\u30e0\u6a5f\u80fd\u3092\u8abf\u7bc0\u3059\u308b\u65b0\u898f\u5206\u5b50\u306e\u6a5f\u80fd\u89e3\u6790","funder_award_id":"19H00416","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G6491562089","display_name":"Comparative survey of endogenous and environmental factors that activate autoinflammatory disease responsible gene products in Turkey and Japan","funder_award_id":"17H04656","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2948410175.pdf","grobid_xml":"https://content.openalex.org/works/W2948410175.grobid-xml"},"referenced_works_count":221,"referenced_works":["https://openalex.org/W925051455","https://openalex.org/W1497331930","https://openalex.org/W1501592961","https://openalex.org/W1514081838","https://openalex.org/W1522206572","https://openalex.org/W1524848610","https://openalex.org/W1529674879","https://openalex.org/W1574117864","https://openalex.org/W1576756779","https://openalex.org/W1589892354","https://openalex.org/W1635307506","https://openalex.org/W1765766961","https://openalex.org/W1812925089","https://openalex.org/W1850539057","https://openalex.org/W1852344107","https://openalex.org/W1864325817","https://openalex.org/W1882905539","https://openalex.org/W1896878812","https://openalex.org/W1915347135","https://openalex.org/W1915707280","https://openalex.org/W1920787626","https://openalex.org/W1953241347","https://openalex.org/W1965668934","https://openalex.org/W1968271544","https://openalex.org/W1969850998","https://openalex.org/W1970203307","https://openalex.org/W1971133541","https://openalex.org/W1971915082","https://openalex.org/W1973626323","https://openalex.org/W1974079188","https://openalex.org/W1974572279","https://openalex.org/W1974687506","https://openalex.org/W1974781808","https://openalex.org/W1975024842","https://openalex.org/W1977884267","https://openalex.org/W1978274182","https://openalex.org/W1980215718","https://openalex.org/W1981163610","https://openalex.org/W1981452702","https://openalex.org/W1989658278","https://openalex.org/W1990535077","https://openalex.org/W1990902267","https://openalex.org/W1991883893","https://openalex.org/W1996264333","https://openalex.org/W1997486254","https://openalex.org/W1997720968","https://openalex.org/W2000054651","https://openalex.org/W2000989585","https://openalex.org/W2004889471","https://openalex.org/W2008873550","https://openalex.org/W2009255343","https://openalex.org/W2009523990","https://openalex.org/W2011253952","https://openalex.org/W2014602273","https://openalex.org/W2015129508","https://openalex.org/W2016776998","https://openalex.org/W2018607502","https://openalex.org/W2019383068","https://openalex.org/W2023850046","https://openalex.org/W2024378513","https://openalex.org/W2025438474","https://openalex.org/W2029696790","https://openalex.org/W2031084334","https://openalex.org/W2034946303","https://openalex.org/W2035467622","https://openalex.org/W2036475326","https://openalex.org/W2040695321","https://openalex.org/W2042433863","https://openalex.org/W2043580036","https://openalex.org/W2043661964","https://openalex.org/W2044001456","https://openalex.org/W2044424089","https://openalex.org/W2048211245","https://openalex.org/W2048698451","https://openalex.org/W2048782984","https://openalex.org/W2050516456","https://openalex.org/W2052474826","https://openalex.org/W2052895824","https://openalex.org/W2055727949","https://openalex.org/W2056496184","https://openalex.org/W2059421466","https://openalex.org/W2061896427","https://openalex.org/W2061954876","https://openalex.org/W2064856766","https://openalex.org/W2064955349","https://openalex.org/W2065103997","https://openalex.org/W2065391130","https://openalex.org/W2068084767","https://openalex.org/W2068619092","https://openalex.org/W2069199612","https://openalex.org/W2069610235","https://openalex.org/W2072723048","https://openalex.org/W2074115529","https://openalex.org/W2074213282","https://openalex.org/W2075286730","https://openalex.org/W2076063079","https://openalex.org/W2078872554","https://openalex.org/W2079882002","https://openalex.org/W2082814058","https://openalex.org/W2089503694","https://openalex.org/W2090556647","https://openalex.org/W2090668142","https://openalex.org/W2092360953","https://openalex.org/W2093524746","https://openalex.org/W2097504851","https://openalex.org/W2099808663","https://openalex.org/W2102429140","https://openalex.org/W2102497552","https://openalex.org/W2102943702","https://openalex.org/W2103649298","https://openalex.org/W2105883701","https://openalex.org/W2107833842","https://openalex.org/W2108373994","https://openalex.org/W2108554603","https://openalex.org/W2109168943","https://openalex.org/W2111897512","https://openalex.org/W2111941249","https://openalex.org/W2112940273","https://openalex.org/W2114737175","https://openalex.org/W2114948357","https://openalex.org/W2115338157","https://openalex.org/W2115867185","https://openalex.org/W2116101489","https://openalex.org/W2119098586","https://openalex.org/W2119422448","https://openalex.org/W2120236484","https://openalex.org/W2123105952","https://openalex.org/W2124335748","https://openalex.org/W2124576546","https://openalex.org/W2125001573","https://openalex.org/W2127314810","https://openalex.org/W2128190429","https://openalex.org/W2128830755","https://openalex.org/W2129195110","https://openalex.org/W2130495917","https://openalex.org/W2130989367","https://openalex.org/W2131694614","https://openalex.org/W2133557129","https://openalex.org/W2135484010","https://openalex.org/W2136434338","https://openalex.org/W2138396727","https://openalex.org/W2139339400","https://openalex.org/W2142151533","https://openalex.org/W2142907755","https://openalex.org/W2143102054","https://openalex.org/W2143658570","https://openalex.org/W2144794315","https://openalex.org/W2145866317","https://openalex.org/W2147454024","https://openalex.org/W2150107812","https://openalex.org/W2150918628","https://openalex.org/W2152847293","https://openalex.org/W2156301166","https://openalex.org/W2158932193","https://openalex.org/W2159587574","https://openalex.org/W2163109807","https://openalex.org/W2163312370","https://openalex.org/W2164013854","https://openalex.org/W2164406361","https://openalex.org/W2165275387","https://openalex.org/W2166452818","https://openalex.org/W2168652736","https://openalex.org/W2171607771","https://openalex.org/W2172171511","https://openalex.org/W2175794645","https://openalex.org/W2177407033","https://openalex.org/W2209731801","https://openalex.org/W2210680772","https://openalex.org/W2254807163","https://openalex.org/W2291703807","https://openalex.org/W2309368936","https://openalex.org/W2401994568","https://openalex.org/W2411514470","https://openalex.org/W2414265798","https://openalex.org/W2414367703","https://openalex.org/W2418806051","https://openalex.org/W2432418760","https://openalex.org/W2461756806","https://openalex.org/W2461915818","https://openalex.org/W2462773201","https://openalex.org/W2523266197","https://openalex.org/W2529393815","https://openalex.org/W2541709983","https://openalex.org/W2552085489","https://openalex.org/W2572024892","https://openalex.org/W2587466142","https://openalex.org/W2587680743","https://openalex.org/W2591028739","https://openalex.org/W2606005532","https://openalex.org/W2624949920","https://openalex.org/W2660194476","https://openalex.org/W2737765537","https://openalex.org/W2738182715","https://openalex.org/W2742869577","https://openalex.org/W2748400555","https://openalex.org/W2750254726","https://openalex.org/W2763597778","https://openalex.org/W2767557499","https://openalex.org/W2767737860","https://openalex.org/W2769149898","https://openalex.org/W2774856823","https://openalex.org/W2789987592","https://openalex.org/W2801633846","https://openalex.org/W2804258587","https://openalex.org/W2804409796","https://openalex.org/W2804888720","https://openalex.org/W2883211872","https://openalex.org/W2883276763","https://openalex.org/W2884462708","https://openalex.org/W2885635355","https://openalex.org/W2890743650","https://openalex.org/W2891569200","https://openalex.org/W2896316685","https://openalex.org/W2903238548","https://openalex.org/W2947812860","https://openalex.org/W3204604741","https://openalex.org/W4240175730","https://openalex.org/W4253920848","https://openalex.org/W4285719527","https://openalex.org/W6802531709","https://openalex.org/W7099868676"],"related_works":["https://openalex.org/W2286427251","https://openalex.org/W2939625028","https://openalex.org/W2166300512","https://openalex.org/W2407175685","https://openalex.org/W4242088769","https://openalex.org/W1973570622","https://openalex.org/W2414218679","https://openalex.org/W2954935920","https://openalex.org/W4242014061","https://openalex.org/W2520886633"],"abstract_inverted_index":{"Interleukin-1,":[0],"an":[1,16],"inflammatory":[2,53],"cytokine,":[3],"is":[4,34],"considered":[5],"to":[6],"have":[7,29],"diverse":[8],"physiological":[9],"functions":[10],"and":[11,14,21,32,70,81],"pathological":[12],"significances":[13],"play":[15],"important":[17],"role":[18],"in":[19,42,66,76,92],"health":[20],"disease.":[22],"In":[23,55],"this":[24,56],"decade,":[25],"interleukin-1":[26,41,75],"family":[27],"members":[28],"been":[30],"expanding":[31],"evidence":[33],"accumulating":[35],"that":[36],"highlights":[37],"the":[38,62,82],"importance":[39],"of":[40,50,64,78,85],"linking":[43],"innate":[44],"immunity":[45],"with":[46],"a":[47],"broad":[48],"spectrum":[49],"diseases":[51],"beyond":[52],"diseases.":[54],"review,":[57],"we":[58],"look":[59],"back":[60],"on":[61],"definition":[63],"\"inflammation\"":[65],"traditional":[67],"general":[68],"pathology":[69],"discuss":[71],"new":[72],"insights":[73],"into":[74],"view":[77],"its":[79],"history":[80],"molecular":[83],"bases":[84],"diseases,":[86],"as":[87,89],"well":[88],"current":[90],"progress":[91],"therapeutics.":[93]},"counts_by_year":[{"year":2026,"cited_by_count":53},{"year":2025,"cited_by_count":109},{"year":2024,"cited_by_count":123},{"year":2023,"cited_by_count":149},{"year":2022,"cited_by_count":105},{"year":2021,"cited_by_count":77},{"year":2020,"cited_by_count":22},{"year":2019,"cited_by_count":2},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2019-06-14T00:00:00"}
