{"id":"https://openalex.org/W2947778367","doi":"https://doi.org/10.1200/jco.2019.37.15_suppl.e18175","title":"Evaluation of Electronic Activity Monitors (EAMs) during phase I clinical trials.","display_name":"Evaluation of Electronic Activity Monitors (EAMs) during phase I clinical trials.","publication_year":2019,"publication_date":"2019-05-20","ids":{"openalex":"https://openalex.org/W2947778367","doi":"https://doi.org/10.1200/jco.2019.37.15_suppl.e18175","mag":"2947778367"},"language":"en","primary_location":{"id":"doi:10.1200/jco.2019.37.15_suppl.e18175","doi":"https://doi.org/10.1200/jco.2019.37.15_suppl.e18175","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2019.37.15_suppl.e18175","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014565080","display_name":"Mariana Scaranti","orcid":"https://orcid.org/0000-0001-7713-0100","observed_orcids":["https://orcid.org/0000-0001-7713-0100"]},"institutions":[{"id":"https://openalex.org/I1325846038","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038"]},{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mariana Scaranti","raw_affiliation_strings":["Drug Development Unit-The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Development Unit-The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom;","institution_ids":["https://openalex.org/I1325846038","https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053619368","display_name":"Raghav Sundar","orcid":"https://orcid.org/0000-0001-9423-1368","observed_orcids":["https://orcid.org/0000-0001-9423-1368"]},"institutions":[{"id":"https://openalex.org/I1325846038","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038"]},{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Raghav Sundar","raw_affiliation_strings":["Drug Development Unit-The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Development Unit-The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom;","institution_ids":["https://openalex.org/I1325846038","https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002588348","display_name":"Robert Michael Daly","orcid":"https://orcid.org/0000-0001-6573-7650","observed_orcids":["https://orcid.org/0000-0001-6573-7650"]},"institutions":[{"id":"https://openalex.org/I1325846038","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038"]},{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Robert Daly","raw_affiliation_strings":["Drug Development Unit-The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Development Unit-The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom;","institution_ids":["https://openalex.org/I1325846038","https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060391756","display_name":"Dearbhaile Catherine Collins","orcid":"https://orcid.org/0000-0002-5156-0142","observed_orcids":["https://orcid.org/0000-0002-5156-0142"]},"institutions":[{"id":"https://openalex.org/I1325846038","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038"]},{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Dearbhaile Catherine Collins","raw_affiliation_strings":["Drug Development Unit-The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Development Unit-The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom;","institution_ids":["https://openalex.org/I1325846038","https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031522630","display_name":"David I. Dolling","orcid":"https://orcid.org/0000-0002-4821-3051","observed_orcids":["https://orcid.org/0000-0002-4821-3051"]},"institutions":[{"id":"https://openalex.org/I1325846038","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038"]},{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David Dolling","raw_affiliation_strings":["Drug Development Unit-The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Development Unit-The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom;","institution_ids":["https://openalex.org/I1325846038","https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031803742","display_name":"Spyridon Gennatas","orcid":"https://orcid.org/0000-0002-5635-7696","observed_orcids":["https://orcid.org/0000-0002-5635-7696"]},"institutions":[{"id":"https://openalex.org/I1325846038","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038"]},{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Spyridon Gennatas","raw_affiliation_strings":["Drug Development Unit-The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Development Unit-The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom;","institution_ids":["https://openalex.org/I1325846038","https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041184791","display_name":"Bindumalini Rao Baikady","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1325846038","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038"]},{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Bindumalini Rao Baikady","raw_affiliation_strings":["Drug Development Unit-The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Development Unit-The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom;","institution_ids":["https://openalex.org/I1325846038","https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014804968","display_name":"Stan B. Kaye","orcid":"https://orcid.org/0000-0003-3318-8575","observed_orcids":["https://orcid.org/0000-0003-3318-8575"]},"institutions":[{"id":"https://openalex.org/I1325846038","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038"]},{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stan B Kaye","raw_affiliation_strings":["Drug Development Unit-The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Development Unit-The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom;","institution_ids":["https://openalex.org/I1325846038","https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032401979","display_name":"Udai Banerji","orcid":"https://orcid.org/0000-0003-1503-3123","observed_orcids":["https://orcid.org/0000-0003-1503-3123"]},"institutions":[{"id":"https://openalex.org/I1325846038","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038"]},{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Udai Banerji","raw_affiliation_strings":["Drug Development Unit-The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Development Unit-The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom;","institution_ids":["https://openalex.org/I1325846038","https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064237640","display_name":"Juanita Suzanne Lopez","orcid":"https://orcid.org/0000-0001-8321-4212","observed_orcids":["https://orcid.org/0000-0001-8321-4212"]},"institutions":[{"id":"https://openalex.org/I1325846038","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038"]},{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Juanita Suzanne Lopez","raw_affiliation_strings":["Drug Development Unit-The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Development Unit-The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom;","institution_ids":["https://openalex.org/I1325846038","https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072378199","display_name":"Johann Sebastian De Bono","orcid":"https://orcid.org/0000-0002-2034-595X","observed_orcids":["https://orcid.org/0000-0002-2034-595X"]},"institutions":[{"id":"https://openalex.org/I1325846038","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038"]},{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Johann S. De Bono","raw_affiliation_strings":["Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, London, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, London, United Kingdom;","institution_ids":["https://openalex.org/I1325846038","https://openalex.org/I142947616"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073795960","display_name":"Anna Rachel Minchom","orcid":"https://orcid.org/0000-0002-9339-7101","observed_orcids":["https://orcid.org/0000-0002-9339-7101"]},"institutions":[{"id":"https://openalex.org/I1325846038","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038"]},{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anna Rachel Minchom","raw_affiliation_strings":["Drug Development Unit-The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Development Unit-The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom;","institution_ids":["https://openalex.org/I1325846038","https://openalex.org/I142947616"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"37","issue":"15_suppl","first_page":"e18175","last_page":"e18175"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11446","display_name":"Mobile Health and mHealth Applications","score":0.2451000064611435,"subfield":{"id":"https://openalex.org/subfields/3600","display_name":"General Health Professions"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11446","display_name":"Mobile Health and mHealth Applications","score":0.2451000064611435,"subfield":{"id":"https://openalex.org/subfields/3600","display_name":"General Health Professions"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10178","display_name":"Cancer survivorship and care","score":0.2222999930381775,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10352","display_name":"Physical Activity and Health","score":0.17800000309944153,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/wearable-devices","display_name":"wearable devices","score":0.8379999995231628},{"id":"https://openalex.org/keywords/fitbit","display_name":"Fitbit","score":0.8569999933242798},{"id":"https://openalex.org/keywords/performance-status","display_name":"performance status","score":0.7960000038146973},{"id":"https://openalex.org/keywords/ecog-performance-status","display_name":"ECOG performance status","score":0.8500000238418579},{"id":"https://openalex.org/keywords/karnofsky-performance-status","display_name":"Karnofsky performance status","score":0.8790000081062317},{"id":"https://openalex.org/keywords/step-count","display_name":"step count","score":0.9629999995231628},{"id":"https://openalex.org/keywords/heart-rate","display_name":"heart rate","score":0.8569999933242798},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.9100000262260437},{"id":"https://openalex.org/keywords/progression-free-survival","display_name":"progression-free survival","score":0.9769999980926514},{"id":"https://openalex.org/keywords/prognostic-score","display_name":"prognostic score","score":0.6290000081062317},{"id":"https://openalex.org/keywords/cancer-patients","display_name":"cancer patients","score":0.5820000171661377}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8993431329727173},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.7334578037261963},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.6654402613639832},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.5554359555244446},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.5339322090148926},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5050848126411438},{"id":"https://openalex.org/C65409693","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Statistical significance","level":2,"score":0.46349549293518066},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.3654748201370239}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1200/jco.2019.37.15_suppl.e18175","doi":"https://doi.org/10.1200/jco.2019.37.15_suppl.e18175","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2019.37.15_suppl.e18175","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.800000011920929}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2889626138","https://openalex.org/W3207836863","https://openalex.org/W2808816741","https://openalex.org/W2802274028","https://openalex.org/W2790621934","https://openalex.org/W2947531499","https://openalex.org/W2557393732","https://openalex.org/W4393278194","https://openalex.org/W3171522477","https://openalex.org/W2589879543"],"abstract_inverted_index":{"e18175":[0],"Background:":[1],"EAMs":[2,52,245,271],"are":[3,39],"wearable":[4],"devices":[5],"that":[6],"record":[7],"aspects":[8],"of":[9,51,125,141,146,244,270,275],"activity,":[10],"including":[11],"heart":[12,156],"rate":[13],"and":[14,26,33,43,64,93,231,288],"step":[15,159,194,229,254],"count.":[16],"Medical":[17],"oncologists":[18],"use":[19,50,243],"performance":[20],"status":[21],"(PS)":[22],"(such":[23],"as":[24,152,272],"ECOG":[25,165,182],"Karnofsky)":[27],"to":[28,34,41,86,91,279],"assess":[29],"patient\u2019s":[30],"physical":[31],"function":[32],"aid":[35],"treatment":[36,97],"decisions.":[37],"These":[38],"subject":[40],"patient":[42,65,250,277],"physician":[44],"bias.":[45],"Our":[46],"study":[47],"evaluated":[48],"the":[49,95,123,136,168,268,289],"(Fitbit":[53],"\u00ae)":[54],"during":[55,94],"phase":[56,82,285],"I":[57,83,286],"trials,":[58],"correlating":[59],"EAM":[60,89,137,300],"indices":[61,301],"with":[62,154,164,197,213,257],"PS":[63,101,166,209,262],"outcomes.":[66],"Methods:":[67],"We":[68],"recruited":[69],"patients":[70,119],"in":[71,80,181,248],"an":[72,88,139],"academic":[73],"hospital":[74],"Drug":[75],"Development":[76],"Unit.":[77],"Patients":[78,134],"participating":[79],"a":[81,273,293],"trial":[84,305],"consented":[85],"wear":[87],"prior":[90],"starting":[92],"first":[96],"cycle.":[98],"Physicians":[99],"assessed":[100],"at":[102],"4":[103],"timepoints.":[104],"Outcomes":[105],"(progression":[106],"free":[107],"survival":[108,111,278],"(PFS),":[109],"overall":[110],"(OS),":[112],"adverse":[113],"events)":[114],"were":[115,120,129],"recorded.":[116],"Results:":[117],"Twenty-five":[118],"enrolled.":[121],"At":[122],"time":[124,148,153],"data":[126],"analysis":[127],"results":[128],"available":[130],"for":[131,138,178,284,291],"16":[132],"patients.":[133],"wore":[135],"average":[140],"70.3%":[142],"(standard":[143],"deviation":[144],"21%)":[145],"their":[147],"on":[149,282],"study,":[150],"defined":[151],"recordable":[155],"rate.":[157],"Mean":[158],"count":[160,230,255],"per":[161],"day":[162],"varied":[163],"although":[167],"correlation":[169,226],"did":[170,210,263],"not":[171,211],"reach":[172],"statistical":[173],"significance":[174],"(co-efficient":[175],"-1611.1":[176],"steps":[177],"each":[179],"change":[180],"PS,":[183],"p":[184,201,216,234],"=":[185,202,217,235],"0.07,":[186],"mixed":[187],"effect":[188],"regression":[189],"model).":[190,207,222,240],"A":[191,252],"higher":[192,253],"mean":[193,228],"count/day":[195],"correlated":[196,256],"longer":[198,258],"OS":[199,214,259],"(HR0.67,":[200],"0.01,":[203],"Cox":[204,219,237],"proportional":[205,220,238],"hazard":[206,221,239],"Physician-assessed":[208],"correlate":[212],"(HR2.65,":[215],"0.37,":[218],"There":[223],"was":[224],"no":[225],"between":[227],"PFS":[232],"(HR1.7,":[233],"0.39,":[236],"Conclusions:":[241],"The":[242],"is":[246,302],"feasible":[247],"this":[249],"group.":[251],"whereas":[260],"physician-assessed":[261],"not.":[264],"Further":[265],"research":[266],"into":[267],"potential":[269,290],"means":[274],"predicting":[276],"guide":[280],"decisions":[281],"eligibility":[283],"trials":[287],"devising":[292],"revised":[294],"Royal":[295],"Marsden":[296],"prognostic":[297],"score":[298],"incorporating":[299],"warranted.":[303],"Clinical":[304],"information:":[306],"SE536.":[307],"[Table:":[308],"see":[309],"text]":[310]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2019-06-07T00:00:00"}