{"id":"https://openalex.org/W2947284292","doi":null,"title":"Dexmedetomidine to control signs associated with lisdexamfetamine dimesylate toxidrome in a cat.","display_name":"Dexmedetomidine to control signs associated with lisdexamfetamine dimesylate toxidrome in a cat.","publication_year":2017,"publication_date":"2017-03-01","ids":{"openalex":"https://openalex.org/W2947284292","mag":"2947284292","pmid":"https://pubmed.ncbi.nlm.nih.gov/28246413","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5302200"},"language":"en","primary_location":{"id":"pmid:28246413","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28246413","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Canadian veterinary journal = La revue veterinaire canadienne","raw_type":"Case Reports"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5302200/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017939606","display_name":"Christopher L. Norkus","orcid":"https://orcid.org/0000-0002-7179-0287","observed_orcids":["https://orcid.org/0000-0002-7179-0287"]},"institutions":[{"id":"https://openalex.org/I4210133558","display_name":"American Society for the Prevention of Cruelty to Animals","ror":"https://ror.org/03bf4az94","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210133558"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher L Norkus","raw_affiliation_strings":["Allegheny Veterinary Emergency Trauma & Specialty, 4224 Northern Pike, Monroeville, Pennsylvania, 15146, USA (Norkus, Keir); ASPCA Animal Poison Control Center, 1717 S Philo Road, Suite 36 Urbana, Illinois 61802, USA (Means)","Allegheny Veterinary Emergency Trauma & Specialty, 4224 Northern Pike, Monroeville, Pennsylvania, 15146, USA (Norkus, Keir)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Allegheny Veterinary Emergency Trauma & Specialty, 4224 Northern Pike, Monroeville, Pennsylvania, 15146, USA (Norkus, Keir); ASPCA Animal Poison Control Center, 1717 S Philo Road, Suite 36 Urbana, Illinois 61802, USA (Means)","institution_ids":["https://openalex.org/I4210133558"]},{"raw_affiliation_string":"Allegheny Veterinary Emergency Trauma & Specialty, 4224 Northern Pike, Monroeville, Pennsylvania, 15146, USA (Norkus, Keir)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006983209","display_name":"Iain Keir","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210133558","display_name":"American Society for the Prevention of Cruelty to Animals","ror":"https://ror.org/03bf4az94","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210133558"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Iain Keir","raw_affiliation_strings":["Allegheny Veterinary Emergency Trauma & Specialty, 4224 Northern Pike, Monroeville, Pennsylvania, 15146, USA (Norkus, Keir); ASPCA Animal Poison Control Center, 1717 S Philo Road, Suite 36 Urbana, Illinois 61802, USA (Means)","ASPCA Animal Poison Control Center, 1717 S Philo Road, Suite 36 Urbana, Illinois 61802, USA (Means)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Allegheny Veterinary Emergency Trauma & Specialty, 4224 Northern Pike, Monroeville, Pennsylvania, 15146, USA (Norkus, Keir); ASPCA Animal Poison Control Center, 1717 S Philo Road, Suite 36 Urbana, Illinois 61802, USA (Means)","institution_ids":["https://openalex.org/I4210133558"]},{"raw_affiliation_string":"ASPCA Animal Poison Control Center, 1717 S Philo Road, Suite 36 Urbana, Illinois 61802, USA (Means)","institution_ids":["https://openalex.org/I4210133558"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073578347","display_name":"Charlotte Means","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210133558","display_name":"American Society for the Prevention of Cruelty to Animals","ror":"https://ror.org/03bf4az94","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210133558"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charlotte Means","raw_affiliation_strings":["Allegheny Veterinary Emergency Trauma & Specialty, 4224 Northern Pike, Monroeville, Pennsylvania, 15146, USA (Norkus, Keir); ASPCA Animal Poison Control Center, 1717 S Philo Road, Suite 36 Urbana, Illinois 61802, USA (Means)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Allegheny Veterinary Emergency Trauma & Specialty, 4224 Northern Pike, Monroeville, Pennsylvania, 15146, USA (Norkus, Keir); ASPCA Animal Poison Control Center, 1717 S Philo Road, Suite 36 Urbana, Illinois 61802, USA (Means)","institution_ids":["https://openalex.org/I4210133558"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210133558"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"58","issue":"3","first_page":"261","last_page":"264"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11905","display_name":"Veterinary Pharmacology and Anesthesia","score":0.676800012588501,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11905","display_name":"Veterinary Pharmacology and Anesthesia","score":0.676800012588501,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11635","display_name":"Poisoning and overdose treatments","score":0.26100000739097595,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10436","display_name":"Anesthesia and Sedative Agents","score":0.039500001817941666,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dexmedetomidine","display_name":"dexmedetomidine","score":0.9190000295639038},{"id":"https://openalex.org/keywords/lisdexamfetamine-dimesylate","display_name":"lisdexamfetamine dimesylate","score":0.9480000138282776},{"id":"https://openalex.org/keywords/drug-toxicity","display_name":"drug toxicity","score":0.628000020980835},{"id":"https://openalex.org/keywords/cats","display_name":"cats","score":0.4519999921321869},{"id":"https://openalex.org/keywords/pupil-dilation","display_name":"pupil dilation","score":0.8640000224113464},{"id":"https://openalex.org/keywords/agitation","display_name":"agitation","score":0.9089999794960022},{"id":"https://openalex.org/keywords/veterinary-toxicology","display_name":"veterinary toxicology","score":0.5920000076293945},{"id":"https://openalex.org/keywords/acepromazine","display_name":"acepromazine","score":0.6150000095367432},{"id":"https://openalex.org/keywords/cyproheptadine","display_name":"cyproheptadine","score":0.9769999980926514},{"id":"https://openalex.org/keywords/intravenous-lipid-emulsion","display_name":"intravenous lipid emulsion","score":0.8740000128746033},{"id":"https://openalex.org/keywords/hematuria","display_name":"hematuria","score":0.753000020980835},{"id":"https://openalex.org/keywords/vomiting","display_name":"vomiting","score":0.9679999947547913}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7093780636787415},{"id":"https://openalex.org/C2778206117","wikidata":"https://www.wikidata.org/wiki/Q417884","display_name":"Cyproheptadine","level":4,"score":0.5789715647697449},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5763277411460876},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.3645526170730591},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.24596551060676575},{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.06678742170333862},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000069478","descriptor_name":"Lisdexamfetamine Dimesylate","qualifier_ui":"Q000506","qualifier_name":"poisoning","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002371","descriptor_name":"Cat Diseases","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D002371","descriptor_name":"Cat Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D002415","descriptor_name":"Cats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020230","descriptor_name":"Serotonin Syndrome","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D020230","descriptor_name":"Serotonin Syndrome","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true},{"descriptor_ui":"D020927","descriptor_name":"Dexmedetomidine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D058647","descriptor_name":"Adrenergic alpha-2 Receptor Agonists","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":3,"locations":[{"id":"pmid:28246413","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28246413","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Canadian veterinary journal = La revue veterinaire canadienne","raw_type":"Case Reports"},{"id":"pmh:oai:pubmedcentral.nih.gov:5302200","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5302200/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Can Vet J","raw_type":"Text"},{"id":"mag:2947284292","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28246413","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:5302200","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5302200/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Can Vet J","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W136595513","https://openalex.org/W1070976522","https://openalex.org/W1505219599","https://openalex.org/W1934404972","https://openalex.org/W2000431779","https://openalex.org/W2026068578","https://openalex.org/W2037476819","https://openalex.org/W2056679792","https://openalex.org/W2060673383","https://openalex.org/W2060932853","https://openalex.org/W2072564314","https://openalex.org/W2073115157","https://openalex.org/W2083135185","https://openalex.org/W2089933786","https://openalex.org/W2093104583","https://openalex.org/W2094627724","https://openalex.org/W2096305131","https://openalex.org/W2107055335","https://openalex.org/W2115910406","https://openalex.org/W2123863334","https://openalex.org/W2136336527","https://openalex.org/W2207256970","https://openalex.org/W2307492078","https://openalex.org/W4390364149"],"related_works":["https://openalex.org/W4396721398","https://openalex.org/W2193999737","https://openalex.org/W4406270344","https://openalex.org/W2955296008","https://openalex.org/W2328355826","https://openalex.org/W2095401610","https://openalex.org/W2377296786","https://openalex.org/W3203112424","https://openalex.org/W4392603569","https://openalex.org/W6941531242"],"abstract_inverted_index":{"A":[0],"5-month-old":[1],"intact":[2],"female":[3],"domestic":[4],"shorthaired":[5],"cat":[6,74],"had":[7],"mydriasis,":[8],"agitation,":[9],"and":[10,31,46,63],"increased":[11],"locomotion":[12],"after":[13,69],"ingestion":[14],"of":[15,61],"lisdexamfetamine,":[16],"10.3":[17],"mg/kg":[18],"body":[19],"weight":[20],"(BW).":[21],"Despite":[22],"treatment":[23],"with":[24],"IV":[25,27],"fluids,":[26],"acepromazine,":[28],"oral":[29],"cyproheptadine":[30],"intravenous":[32],"lipid":[33],"emulsion":[34],"the":[35,56,73],"patient's":[36,57],"clinical":[37],"signs":[38],"worsened.":[39],"Dexmedetomidine":[40],"administered":[41],"at":[42,48],"2":[43],"\u03bcg/kg":[44,50],"BW":[45,51],"continued":[47],"0.5":[49],"per":[52],"hour":[53],"rapidly":[54],"controlled":[55],"signs.":[58],"An":[59],"episode":[60],"vomiting":[62],"hematuria":[64],"developed.":[65],"Follow-up":[66],"5":[67],"days":[68],"discharge":[70],"revealed":[71],"that":[72],"appeared":[75],"normal.":[76]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2019-06-07T00:00:00"}