{"id":"https://openalex.org/W2947053774","doi":"https://doi.org/10.3389/fphys.2019.00691","title":"Myokine/Adipokine Response to \u201cAerobic\u201d Exercise: Is It Just a Matter of Exercise Load?","display_name":"Myokine/Adipokine Response to \u201cAerobic\u201d Exercise: Is It Just a Matter of Exercise Load?","publication_year":2019,"publication_date":"2019-05-29","ids":{"openalex":"https://openalex.org/W2947053774","doi":"https://doi.org/10.3389/fphys.2019.00691","mag":"2947053774","pmid":"https://pubmed.ncbi.nlm.nih.gov/31191366","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6549222"},"language":"en","primary_location":{"id":"doi:10.3389/fphys.2019.00691","doi":"https://doi.org/10.3389/fphys.2019.00691","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fphys.2019.00691","pdf_url":"https://www.frontiersin.org/articles/10.3389/fphys.2019.00691/pdf","source":{"id":"https://openalex.org/S52732750","display_name":"Frontiers in Physiology","issn_l":"1664-042X","issn":["1664-042X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Physiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fphys.2019.00691/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100509886","display_name":"Zihong He","orcid":"https://orcid.org/0000-0002-0241-726X","observed_orcids":["https://orcid.org/0000-0002-0241-726X"]},"institutions":[{"id":"https://openalex.org/I4210132072","display_name":"China Institute of Sport Science","ror":"https://ror.org/03sgtek58","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210132072"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zihong He","raw_affiliation_strings":["Biology Center, China Institute of Sport Science, Beijing, China","Cardiovascular Department, Beijing Jian Gong Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Center, China Institute of Sport Science, Beijing, China","institution_ids":["https://openalex.org/I4210132072"]},{"raw_affiliation_string":"Cardiovascular Department, Beijing Jian Gong Hospital, Beijing, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052053900","display_name":"Ye Tian","orcid":"https://orcid.org/0000-0001-7819-6240","observed_orcids":["https://orcid.org/0000-0001-7819-6240"]},"institutions":[{"id":"https://openalex.org/I4210111200","display_name":"General Administration of Sport of China","ror":"https://ror.org/021jpad90","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210111200","https://openalex.org/I4210127390"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ye Tian","raw_affiliation_strings":["Culture Development Center, General Administration of Sport of China, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Culture Development Center, General Administration of Sport of China, Beijing, China","institution_ids":["https://openalex.org/I4210111200"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065959280","display_name":"Pedro L. Valenzuela","orcid":"https://orcid.org/0000-0003-1730-3369","observed_orcids":["https://orcid.org/0000-0003-1730-3369"]},"institutions":[{"id":"https://openalex.org/I189268942","display_name":"Universidad de Alcal\u00e1","ror":"https://ror.org/04pmn0e78","country_code":"ES","type":"education","lineage":["https://openalex.org/I189268942"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Pedro L. Valenzuela","raw_affiliation_strings":["Physiology Unit, Department of Systems Biology, University of Alcal\u00e1, Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Physiology Unit, Department of Systems Biology, University of Alcal\u00e1, Madrid, Spain","institution_ids":["https://openalex.org/I189268942"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100997876","display_name":"Chuanye Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210116868","display_name":"Shandong Sport University","ror":"https://ror.org/026b4k258","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210116868"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chuanye Huang","raw_affiliation_strings":["Graduate School, Shandong Sport University, Jinan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School, Shandong Sport University, Jinan, China","institution_ids":["https://openalex.org/I4210116868"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060102665","display_name":"Jiexiu Zhao","orcid":"https://orcid.org/0000-0002-7507-5272","observed_orcids":["https://orcid.org/0000-0002-7507-5272"]},"institutions":[{"id":"https://openalex.org/I4210132072","display_name":"China Institute of Sport Science","ror":"https://ror.org/03sgtek58","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210132072"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiexiu Zhao","raw_affiliation_strings":["Biology Center, China Institute of Sport Science, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Center, China Institute of Sport Science, Beijing, China","institution_ids":["https://openalex.org/I4210132072"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102212655","display_name":"Ping Hong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210111200","display_name":"General Administration of Sport of China","ror":"https://ror.org/021jpad90","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210111200","https://openalex.org/I4210127390"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ping Hong","raw_affiliation_strings":["Winter Sports Administrative Center, General Administration of Sport of China, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Winter Sports Administrative Center, General Administration of Sport of China, Beijing, China","institution_ids":["https://openalex.org/I4210111200"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067222850","display_name":"Zilin He","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210132072","display_name":"China Institute of Sport Science","ror":"https://ror.org/03sgtek58","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210132072"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zilin He","raw_affiliation_strings":["Biology Center, China Institute of Sport Science, Beijing, China","Cardiovascular Department, Beijing Jian Gong Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Center, China Institute of Sport Science, Beijing, China","institution_ids":["https://openalex.org/I4210132072"]},{"raw_affiliation_string":"Cardiovascular Department, Beijing Jian Gong Hospital, Beijing, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060193772","display_name":"Shuhui Yin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160531","display_name":"Chinese People's Liberation Army","ror":"https://ror.org/05tf9r976","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210160531"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuhui Yin","raw_affiliation_strings":["The Rocket Force General Hospital of PLA, Institute of Hepatobiliary Gastrointestinal Disease, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Rocket Force General Hospital of PLA, Institute of Hepatobiliary Gastrointestinal Disease, Beijing, China","institution_ids":["https://openalex.org/I4210160531"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070457235","display_name":"Alejandro Luc\u00eda","orcid":"https://orcid.org/0000-0002-5565-0997","observed_orcids":["https://orcid.org/0000-0002-5565-0997"]},"institutions":[{"id":"https://openalex.org/I4210086614","display_name":"Research Institute Hospital 12 de Octubre","ror":"https://ror.org/002x1sg85","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210086614"]},{"id":"https://openalex.org/I904013037","display_name":"Universidad Europea de Madrid","ror":"https://ror.org/04dp46240","country_code":"ES","type":"education","lineage":["https://openalex.org/I904013037"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Alejandro Lucia","raw_affiliation_strings":["Faculty of Sport Sciences, European University of Madrid, Madrid, Spain","Institute Hospital 12 de Octubre, Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Sport Sciences, European University of Madrid, Madrid, Spain","institution_ids":["https://openalex.org/I904013037"]},{"raw_affiliation_string":"Institute Hospital 12 de Octubre, Madrid, Spain","institution_ids":["https://openalex.org/I4210086614"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5052053900"],"corresponding_institution_ids":["https://openalex.org/I4210111200"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":5.4941,"has_fulltext":true,"cited_by_count":60,"citation_normalized_percentile":{"value":0.96751478,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"10","issue":null,"first_page":"691","last_page":"691"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11585","display_name":"Exercise and Physiological Responses","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11585","display_name":"Exercise and Physiological Responses","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myokines","display_name":"myokines","score":0.9850000143051147},{"id":"https://openalex.org/keywords/adipokines","display_name":"adipokines","score":1.0},{"id":"https://openalex.org/keywords/aerobic-exercise","display_name":"aerobic exercise","score":0.9580000042915344},{"id":"https://openalex.org/keywords/exercise-intensity","display_name":"exercise intensity","score":0.9380000233650208},{"id":"https://openalex.org/keywords/fat-oxidation-rate","display_name":"fat oxidation rate","score":0.6240000128746033},{"id":"https://openalex.org/keywords/anaerobic-threshold","display_name":"anaerobic threshold","score":0.972000002861023},{"id":"https://openalex.org/keywords/fgf21","display_name":"FGF21","score":0.8899999856948853},{"id":"https://openalex.org/keywords/follistatin","display_name":"follistatin","score":0.9629999995231628},{"id":"https://openalex.org/keywords/myostatin","display_name":"myostatin","score":0.871999979019165},{"id":"https://openalex.org/keywords/irisin","display_name":"irisin","score":0.7960000038146973},{"id":"https://openalex.org/keywords/resistin","display_name":"resistin","score":0.9150000214576721},{"id":"https://openalex.org/keywords/omentin","display_name":"omentin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/il-15","display_name":"IL-15","score":0.9860000014305115},{"id":"https://openalex.org/keywords/inter-individual-variability","display_name":"interindividual variability","score":0.6019999980926514},{"id":"https://openalex.org/keywords/acute-exercise-response","display_name":"acute exercise response","score":0.6349999904632568},{"id":"https://openalex.org/keywords/cardiometabolic-health","display_name":"cardiometabolic health","score":0.7639999985694885},{"id":"https://openalex.org/keywords/personalized-exercise-prescription","display_name":"individualized exercise prescription","score":0.9010000228881836}],"concepts":[{"id":"https://openalex.org/C117365660","wikidata":"https://www.wikidata.org/wiki/Q962589","display_name":"Myokine","level":3,"score":0.908930778503418},{"id":"https://openalex.org/C194832188","wikidata":"https://www.wikidata.org/wiki/Q2638593","display_name":"Adipokine","level":4,"score":0.7995510101318359},{"id":"https://openalex.org/C2779760629","wikidata":"https://www.wikidata.org/wiki/Q419499","display_name":"Resistin","level":5,"score":0.7448475956916809},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6949166059494019},{"id":"https://openalex.org/C103038586","wikidata":"https://www.wikidata.org/wiki/Q1152037","display_name":"Aerobic exercise","level":2,"score":0.6386308670043945},{"id":"https://openalex.org/C2778831791","wikidata":"https://www.wikidata.org/wiki/Q408122","display_name":"Follistatin","level":2,"score":0.6283969283103943},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6235703229904175},{"id":"https://openalex.org/C5140985","wikidata":"https://www.wikidata.org/wiki/Q483866","display_name":"Anaerobic exercise","level":2,"score":0.604656994342804},{"id":"https://openalex.org/C2776782570","wikidata":"https://www.wikidata.org/wiki/Q357439","display_name":"Adiponectin","level":4,"score":0.5616341829299927},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5232164859771729},{"id":"https://openalex.org/C106646824","wikidata":"https://www.wikidata.org/wiki/Q5425475","display_name":"FGF21","level":4,"score":0.49878740310668945},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.4945952594280243},{"id":"https://openalex.org/C2776811442","wikidata":"https://www.wikidata.org/wiki/Q5420058","display_name":"Exercise intensity","level":4,"score":0.48942700028419495},{"id":"https://openalex.org/C133165541","wikidata":"https://www.wikidata.org/wiki/Q472094","display_name":"Exercise physiology","level":2,"score":0.4610286355018616},{"id":"https://openalex.org/C43893838","wikidata":"https://www.wikidata.org/wiki/Q840545","display_name":"Sports medicine","level":2,"score":0.4318099617958069},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.3782733678817749},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.2842617630958557},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.22011271119117737},{"id":"https://openalex.org/C2780613262","wikidata":"https://www.wikidata.org/wiki/Q223739","display_name":"Leptin","level":3,"score":0.19786477088928223},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.13188797235488892},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07430264353752136},{"id":"https://openalex.org/C2779959927","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Skeletal muscle","level":2,"score":0.06632205843925476},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.06286481022834778},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C74373430","wikidata":"https://www.wikidata.org/wiki/Q24727126","display_name":"Fibroblast growth factor","level":3,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.3389/fphys.2019.00691","doi":"https://doi.org/10.3389/fphys.2019.00691","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fphys.2019.00691","pdf_url":"https://www.frontiersin.org/articles/10.3389/fphys.2019.00691/pdf","source":{"id":"https://openalex.org/S52732750","display_name":"Frontiers in Physiology","issn_l":"1664-042X","issn":["1664-042X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Physiology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6549222","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6549222","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Physiol","raw_type":"Text"},{"id":"pmid:31191366","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31191366","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in physiology","raw_type":"Journal Article"},{"id":"pmh:oai:abacus.universidadeuropea.es:11268/8009","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11268/8009","pdf_url":null,"source":{"id":"https://openalex.org/S4306400164","display_name":"ABACUS. Repositorio de Producci\u00f3n Cient\u00edfica (Universidad Europea)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210101845","host_organization_name":"Universidad Europea","host_organization_lineage":["https://openalex.org/I4210101845"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:dnet:abacusreposi::0ba6cd35ba21c3438c60b3e7628732c1","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11268/8009","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:9daf8c7028474873bcca332bca97b874","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/9daf8c7028474873bcca332bca97b874","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Physiology, Vol 10 (2019)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fphys.2019.00691","doi":"https://doi.org/10.3389/fphys.2019.00691","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fphys.2019.00691","pdf_url":"https://www.frontiersin.org/articles/10.3389/fphys.2019.00691/pdf","source":{"id":"https://openalex.org/S52732750","display_name":"Frontiers in Physiology","issn_l":"1664-042X","issn":["1664-042X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Physiology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4395435579","display_name":null,"funder_award_id":"PI15/00558","funder_id":"https://openalex.org/F4320315062","funder_display_name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades"},{"id":"https://openalex.org/G4739922528","display_name":null,"funder_award_id":"PI18/00139","funder_id":"https://openalex.org/F4320315062","funder_display_name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades"},{"id":"https://openalex.org/G6473831934","display_name":null,"funder_award_id":"FPI-2016","funder_id":"https://openalex.org/F4320323755","funder_display_name":"Universidad de Alcal\u00e1"}],"funders":[{"id":"https://openalex.org/F4320315062","display_name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","ror":null},{"id":"https://openalex.org/F4320323755","display_name":"Universidad de Alcal\u00e1","ror":"https://ror.org/04pmn0e78"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2947053774.pdf","grobid_xml":"https://content.openalex.org/works/W2947053774.grobid-xml"},"referenced_works_count":65,"referenced_works":["https://openalex.org/W1675830194","https://openalex.org/W1889306687","https://openalex.org/W1967235595","https://openalex.org/W1972641070","https://openalex.org/W1982144304","https://openalex.org/W1983948326","https://openalex.org/W1987691949","https://openalex.org/W1996107089","https://openalex.org/W2000828095","https://openalex.org/W2006497677","https://openalex.org/W2010095254","https://openalex.org/W2020374367","https://openalex.org/W2027076461","https://openalex.org/W2029557372","https://openalex.org/W2032438142","https://openalex.org/W2033740628","https://openalex.org/W2039620410","https://openalex.org/W2040613256","https://openalex.org/W2040642734","https://openalex.org/W2049686068","https://openalex.org/W2051977733","https://openalex.org/W2053614711","https://openalex.org/W2055557153","https://openalex.org/W2068419938","https://openalex.org/W2074508374","https://openalex.org/W2077088386","https://openalex.org/W2081671819","https://openalex.org/W2085076894","https://openalex.org/W2085379045","https://openalex.org/W2091671277","https://openalex.org/W2096061116","https://openalex.org/W2097491325","https://openalex.org/W2097880214","https://openalex.org/W2105874826","https://openalex.org/W2106366655","https://openalex.org/W2108149639","https://openalex.org/W2117457995","https://openalex.org/W2117693758","https://openalex.org/W2117994923","https://openalex.org/W2123840304","https://openalex.org/W2124589753","https://openalex.org/W2132596222","https://openalex.org/W2134802533","https://openalex.org/W2143024501","https://openalex.org/W2154083884","https://openalex.org/W2158419796","https://openalex.org/W2163644328","https://openalex.org/W2166595292","https://openalex.org/W2167344369","https://openalex.org/W2169246660","https://openalex.org/W2170920749","https://openalex.org/W2314666953","https://openalex.org/W2323235623","https://openalex.org/W2324159567","https://openalex.org/W2331533968","https://openalex.org/W2462198031","https://openalex.org/W2587815451","https://openalex.org/W2595110869","https://openalex.org/W2609404488","https://openalex.org/W2742580886","https://openalex.org/W2819590775","https://openalex.org/W2887420502","https://openalex.org/W2902193521","https://openalex.org/W2910645983","https://openalex.org/W3035240210"],"related_works":["https://openalex.org/W2902193521","https://openalex.org/W3167716063","https://openalex.org/W7118188492","https://openalex.org/W4286214353","https://openalex.org/W3130699216","https://openalex.org/W7165655139","https://openalex.org/W2970875304","https://openalex.org/W1991146173","https://openalex.org/W7047747870","https://openalex.org/W3170612811"],"abstract_inverted_index":{"Purpose:":[0],"Exercise":[1],"health":[2],"benefits":[3],"are":[4],"partly":[5],"mediated":[6],"by":[7],"exertional":[8],"changes":[9],"in":[10,25,154],"several":[11],"myokines/adipokines.":[12],"but":[13],"little":[14],"is":[15,21],"known":[16],"on":[17,180,186],"individual":[18,208],"variability,":[19],"which":[20],"an":[22],"important":[23],"question":[24],"the":[26,37,50,54,61,159,169,181,187],"context":[27],"of":[28,40,42,97,135,158,183,189],"personalized":[29],"exercise":[30,47,80,93,125,145,198],"prescription.":[31],"This":[32],"study":[33],"aimed":[34],"to":[35,45,53,150,165],"compare":[36],"acute":[38],"response":[39,157,164],"some":[41],"these":[43],"biomarkers":[44],"aerobic":[46,166],"performed":[48,77,127],"at":[49,82,111,128],"intensity":[51,87,131,146,175],"corresponding":[52],"maximum":[55],"fat":[56],"oxidation":[57],"rate":[58,188],"(FATmax)":[59],"or":[60,85,185],"\u2018anaerobic\u2019":[62],"threshold":[63],"(AT).":[64],"Methods:":[65],"Following":[66],"a":[67,78,129,155,205],"cross-over,":[68],"counterbalanced":[69],"design,":[70],"14":[71],"healthy":[72],"untrained":[73],"men":[74],"(23\u00b11":[75],"years)":[76],"45-minute":[79],"bout":[81],"their":[83],"FATmax":[84,149],"AT":[86,124],"(been":[88],"previously":[89],"determined":[90],"through":[91],"incremental":[92],"tests).":[94],"The":[95],"concentration":[96],"interleukin":[98],"(IL)-15,":[99],"follistatin,":[100],"myostatin,":[101],"fibroblast-growth":[102],"factor":[103],"(FGF)-21,":[104],"irisin,":[105],"resistin":[106],"and":[107,113,119,162],"omentin":[108,163],"was":[109,126],"measured":[110],"baseline":[112],"0,":[114],"1,":[115],"3,":[116],"24,":[117],"48":[118],"72":[120],"hours":[121],"post-exercise.":[122],"Results:":[123],"higher":[130,156,206],"(85\u00b18":[132],"vs":[133],"52\u00b114%":[134],"maximal":[136],"oxygen":[137],"uptake":[138],"[VO2max],":[139],"p0.05).":[140],"Conclusion:":[141],"In":[142],"summary,":[143],"Iincreasing":[144],"load":[147],"(from":[148],"AT)":[151],"maximizes":[152],"results":[153],"FGF-21,":[160],"follistatin":[161],"exercise,":[167],"with":[168],"subsequent":[170],"potential":[171],"cardiometabolic":[172],"benefits.":[173],"No":[174],"effects":[176],"were,":[177],"however,":[178],"observed":[179],"remainder":[182],"biomarkers.":[184],"responsiveness.":[190],"Future":[191],"research":[192],"should":[193],"address":[194],"if":[195],"manipulating":[196],"other":[197],"variables":[199],"(e.g.,":[200],"type,":[201],"frequency)":[202],"can":[203],"promote":[204],"myokine/adipokine":[207],"responsivenessresponse.":[209]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":12},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2019-06-07T00:00:00"}