{"id":"https://openalex.org/W2946966201","doi":"https://doi.org/10.1161/jaha.119.012503","title":"Association of Antidepressant Medication Type With the Incidence of Cardiovascular Disease in the ARIC Study","display_name":"Association of Antidepressant Medication Type With the Incidence of Cardiovascular Disease in the ARIC Study","publication_year":2019,"publication_date":"2019-05-29","ids":{"openalex":"https://openalex.org/W2946966201","doi":"https://doi.org/10.1161/jaha.119.012503","mag":"2946966201","pmid":"https://pubmed.ncbi.nlm.nih.gov/31140335","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6585369"},"language":"en","primary_location":{"id":"doi:10.1161/jaha.119.012503","doi":"https://doi.org/10.1161/jaha.119.012503","is_oa":true,"landing_page_url":"https://doi.org/10.1161/jaha.119.012503","pdf_url":null,"source":{"id":"https://openalex.org/S2489920150","display_name":"Journal of the American Heart Association","issn_l":"2047-9980","issn":["2047-9980"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Heart Association","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1161/jaha.119.012503","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076445775","display_name":"Zakaria Almuwaqqat","orcid":"https://orcid.org/0000-0001-6606-1031","observed_orcids":["https://orcid.org/0000-0001-6606-1031"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Zakaria Almuwaqqat","raw_affiliation_strings":["Department of Medicine Emory University School of Medicine Atlanta GA","Division of Cardiology Department of Medicine Emory University School of Medicine Atlanta GA","Zakaria Almuwaqqat Department of Medicine, Emory University School of Medicine, Atlanta, GA Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine Emory University School of Medicine Atlanta GA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Division of Cardiology Department of Medicine Emory University School of Medicine Atlanta GA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Zakaria Almuwaqqat Department of Medicine, Emory University School of Medicine, Atlanta, GA Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052230786","display_name":"Maan Jokhadar","orcid":"https://orcid.org/0009-0009-0882-2133","observed_orcids":["https://orcid.org/0009-0009-0882-2133"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maan Jokhadar","raw_affiliation_strings":["Division of Cardiology Department of Medicine Emory University School of Medicine Atlanta GA","Maan Jokhadar Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology Department of Medicine Emory University School of Medicine Atlanta GA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Maan Jokhadar Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071468650","display_name":"Faye L. Norby","orcid":"https://orcid.org/0000-0002-1975-0405","observed_orcids":["https://orcid.org/0000-0002-1975-0405"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Faye L. Norby","raw_affiliation_strings":["Division of Epidemiology &amp; Community Health School of Public Health University of Minnesota Minneapolis MN","Faye L. Norby Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Epidemiology &amp; Community Health School of Public Health University of Minnesota Minneapolis MN","institution_ids":["https://openalex.org/I130238516"]},{"raw_affiliation_string":"Faye L. Norby Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, MN","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082266331","display_name":"Pamela L. Lutsey","orcid":"https://orcid.org/0000-0002-1572-1340","observed_orcids":["https://orcid.org/0000-0002-1572-1340"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pamela L. Lutsey","raw_affiliation_strings":["Division of Epidemiology &amp; Community Health School of Public Health University of Minnesota Minneapolis MN","Pamela L. Lutsey Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Epidemiology &amp; Community Health School of Public Health University of Minnesota Minneapolis MN","institution_ids":["https://openalex.org/I130238516"]},{"raw_affiliation_string":"Pamela L. Lutsey Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, MN","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024344773","display_name":"Wesley T. O\u2019Neal","orcid":"https://orcid.org/0000-0003-0751-4760","observed_orcids":["https://orcid.org/0000-0003-0751-4760"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wesley T. O'Neal","raw_affiliation_strings":["Division of Cardiology Department of Medicine Emory University School of Medicine Atlanta GA","Wesley T. O'Neal Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology Department of Medicine Emory University School of Medicine Atlanta GA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Wesley T. O'Neal Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040913139","display_name":"Amanda A. Seyerle","orcid":"https://orcid.org/0000-0001-5660-3837","observed_orcids":["https://orcid.org/0000-0001-5660-3837"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amanda Seyerle","raw_affiliation_strings":["Eshelman School of Pharmacy University of North Carolina Chapel Hill NC","Amanda Seyerle Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Eshelman School of Pharmacy University of North Carolina Chapel Hill NC","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"Amanda Seyerle Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046831441","display_name":"Elsayed Z. Soliman","orcid":"https://orcid.org/0000-0001-5632-8150","observed_orcids":["https://orcid.org/0000-0001-5632-8150"]},"institutions":[{"id":"https://openalex.org/I4405269449","display_name":"Wake Forest University Health Sciences","ror":"https://ror.org/046r1r105","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4405269449","https://openalex.org/I47251452"]},{"id":"https://openalex.org/I47251452","display_name":"Wake Forest University","ror":"https://ror.org/0207ad724","country_code":"US","type":"education","lineage":["https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elsayed Z. Soliman","raw_affiliation_strings":["Department of Epidemiology and Prevention Epidemiological Cardiology Research Center Wake Forest School of Medicine Winston\u2010Salem NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Prevention Epidemiological Cardiology Research Center Wake Forest School of Medicine Winston\u2010Salem NC","institution_ids":["https://openalex.org/I4405269449","https://openalex.org/I47251452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090746361","display_name":"Lin Y. Chen","orcid":"https://orcid.org/0000-0002-0700-814X","observed_orcids":["https://orcid.org/0000-0002-0700-814X"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lin Y. Chen","raw_affiliation_strings":["Cardiovascular Division Department of Medicine University of Minnesota Medical School Minneapolis MN","Lin Y. Chen Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Division Department of Medicine University of Minnesota Medical School Minneapolis MN","institution_ids":["https://openalex.org/I130238516"]},{"raw_affiliation_string":"Lin Y. Chen Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090528070","display_name":"J. Douglas Bremner","orcid":"https://orcid.org/0000-0003-1633-6433","observed_orcids":["https://orcid.org/0000-0003-1633-6433"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I4210152539","display_name":"Atlanta VA Medical Center","ror":"https://ror.org/04z89xx32","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210131075","https://openalex.org/I4210149289","https://openalex.org/I4210152539"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Douglas Bremner","raw_affiliation_strings":["Atlanta VA Medical Center Decatur GA","Department of Psychiatry &amp; Behavioral Sciences Emory University School of Medicine Atlanta GA","J. Douglas Bremner Department of Psychiatry & Behavioral Sciences, Emory University School of Medicine, Atlanta, GA Atlanta VA Medical Center, Decatur, GA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Atlanta VA Medical Center Decatur GA","institution_ids":["https://openalex.org/I4210152539"]},{"raw_affiliation_string":"Department of Psychiatry &amp; Behavioral Sciences Emory University School of Medicine Atlanta GA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"J. Douglas Bremner Department of Psychiatry & Behavioral Sciences, Emory University School of Medicine, Atlanta, GA Atlanta VA Medical Center, Decatur, GA","institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4210152539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054714854","display_name":"Viola Vaccarino","orcid":"https://orcid.org/0000-0002-9054-0654","observed_orcids":["https://orcid.org/0000-0002-9054-0654"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Viola Vaccarino","raw_affiliation_strings":["Department of Epidemiology Rollins School of Public Health Emory University Atlanta GA","Division of Cardiology Department of Medicine Emory University School of Medicine Atlanta GA","Viola Vaccarino Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology Rollins School of Public Health Emory University Atlanta GA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Division of Cardiology Department of Medicine Emory University School of Medicine Atlanta GA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Viola Vaccarino Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058902301","display_name":"Amit Jasvant Shah","orcid":"https://orcid.org/0000-0001-9099-9687","observed_orcids":["https://orcid.org/0000-0001-9099-9687"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I4210152539","display_name":"Atlanta VA Medical Center","ror":"https://ror.org/04z89xx32","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210131075","https://openalex.org/I4210149289","https://openalex.org/I4210152539"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amit J. Shah","raw_affiliation_strings":["Atlanta VA Medical Center Decatur GA","Department of Epidemiology Rollins School of Public Health Emory University Atlanta GA","Division of Cardiology Department of Medicine Emory University School of Medicine Atlanta GA","Amit J. Shah Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA Atlanta VA Medical Center, Decatur, GA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Atlanta VA Medical Center Decatur GA","institution_ids":["https://openalex.org/I4210152539"]},{"raw_affiliation_string":"Department of Epidemiology Rollins School of Public Health Emory University Atlanta GA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Division of Cardiology Department of Medicine Emory University School of Medicine Atlanta GA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Amit J. Shah Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA Atlanta VA Medical Center, Decatur, GA","institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4210152539"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004776448","display_name":"\u00c1lvaro Alonso","orcid":"https://orcid.org/0000-0002-2225-8323","observed_orcids":["https://orcid.org/0000-0002-2225-8323"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alvaro Alonso","raw_affiliation_strings":["Department of Epidemiology Rollins School of Public Health Emory University Atlanta GA","Alvaro Alonso Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology Rollins School of Public Health Emory University Atlanta GA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Alvaro Alonso Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA","institution_ids":["https://openalex.org/I150468666"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5076445775"],"corresponding_institution_ids":["https://openalex.org/I150468666"],"apc_list":{"value":2750,"currency":"USD","value_usd":2750},"apc_paid":{"value":2750,"currency":"USD","value_usd":2750},"fwci":3.4308,"has_fulltext":false,"cited_by_count":42,"citation_normalized_percentile":{"value":0.93628095,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"8","issue":"11","first_page":"e012503","last_page":"e012503"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11083","display_name":"Cardiac Health and Mental Health","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11083","display_name":"Cardiac Health and Mental Health","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.00860000029206276,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antidepressants","display_name":"antidepressants","score":0.859000027179718},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.7689999938011169},{"id":"https://openalex.org/keywords/selective-serotonin-reuptake-inhibitors","display_name":"selective serotonin reuptake inhibitors","score":0.9990000128746033},{"id":"https://openalex.org/keywords/tricyclic-antidepressants","display_name":"tricyclic antidepressants","score":0.9980000257492065},{"id":"https://openalex.org/keywords/atrial-fibrillation","display_name":"atrial fibrillation","score":0.968999981880188},{"id":"https://openalex.org/keywords/heart-failure","display_name":"heart failure","score":1.0},{"id":"https://openalex.org/keywords/myocardial-infarction","display_name":"myocardial infarction","score":1.0},{"id":"https://openalex.org/keywords/ischemic-stroke","display_name":"ischemic stroke","score":1.0},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.6940000057220459},{"id":"https://openalex.org/keywords/atherosclerosis-risk-in-communities-study","display_name":"Atherosclerosis Risk in Communities Study","score":0.7310000061988831}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9030214548110962},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.7897326946258545},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.720973014831543},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.6838505268096924},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.6540273427963257},{"id":"https://openalex.org/C2779177272","wikidata":"https://www.wikidata.org/wiki/Q76560","display_name":"Antidepressant","level":3,"score":0.6255761384963989},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.5899735689163208},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.5369334816932678},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4420568346977234},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.23491689562797546},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000339","descriptor_name":"Affect","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000928","descriptor_name":"Antidepressive Agents","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D000928","descriptor_name":"Antidepressive Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000929","descriptor_name":"Antidepressive Agents, Tricyclic","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D015994","descriptor_name":"Incidence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017367","descriptor_name":"Selective Serotonin Reuptake Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D018570","descriptor_name":"Risk Assessment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1161/jaha.119.012503","doi":"https://doi.org/10.1161/jaha.119.012503","is_oa":true,"landing_page_url":"https://doi.org/10.1161/jaha.119.012503","pdf_url":null,"source":{"id":"https://openalex.org/S2489920150","display_name":"Journal of the American Heart Association","issn_l":"2047-9980","issn":["2047-9980"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Heart Association","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6585369","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6585369","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Am Heart Assoc","raw_type":"Text"},{"id":"pmid:31140335","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31140335","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Heart Association","raw_type":"Comparative Study"},{"id":"pmh:oai:doaj.org/article:d9783b2e62fe4a3ba3ab94e61c640290","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/d9783b2e62fe4a3ba3ab94e61c640290","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 11 (2019)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1161/jaha.119.012503","doi":"https://doi.org/10.1161/jaha.119.012503","is_oa":true,"landing_page_url":"https://doi.org/10.1161/jaha.119.012503","pdf_url":null,"source":{"id":"https://openalex.org/S2489920150","display_name":"Journal of the American Heart Association","issn_l":"2047-9980","issn":["2047-9980"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Heart Association","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.8600000143051147,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1114307781","display_name":null,"funder_award_id":"HHSN268201700004I","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G3973572274","display_name":null,"funder_award_id":"HHSN268201700001I","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G4790942633","display_name":null,"funder_award_id":"HHSN268201700003I","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5541543554","display_name":"Atrial fibrillation: epidemiology, prevention, and outcomes","funder_award_id":"16EIA26410001","funder_id":"https://openalex.org/F4320306230","funder_display_name":"American Heart Association"},{"id":"https://openalex.org/G5666298042","display_name":"Biological Correlates of Traumatic Stress","funder_award_id":"K24MH076955","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G5770678025","display_name":null,"funder_award_id":"HHSN268201700005I","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6001546009","display_name":"Mind-Body Interactions in Cardiovascular Disease","funder_award_id":"K24HL077506","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6837735701","display_name":null,"funder_award_id":"HHSN268201700002I","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320306230","display_name":"American Heart Association","ror":"https://ror.org/013kjyp64"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W141966528","https://openalex.org/W1565566980","https://openalex.org/W1767184367","https://openalex.org/W1967986324","https://openalex.org/W1971211622","https://openalex.org/W1975450391","https://openalex.org/W1979026637","https://openalex.org/W1988647289","https://openalex.org/W1990315121","https://openalex.org/W1997712205","https://openalex.org/W2006509651","https://openalex.org/W2014763496","https://openalex.org/W2017554908","https://openalex.org/W2023798019","https://openalex.org/W2024993254","https://openalex.org/W2037647232","https://openalex.org/W2038981426","https://openalex.org/W2047120013","https://openalex.org/W2051290466","https://openalex.org/W2062737335","https://openalex.org/W2072245969","https://openalex.org/W2073642733","https://openalex.org/W2074335684","https://openalex.org/W2075265772","https://openalex.org/W2076992142","https://openalex.org/W2101820523","https://openalex.org/W2103751012","https://openalex.org/W2104058480","https://openalex.org/W2127954251","https://openalex.org/W2129413040","https://openalex.org/W2129624996","https://openalex.org/W2130874418","https://openalex.org/W2131690429","https://openalex.org/W2145270758","https://openalex.org/W2149683435","https://openalex.org/W2154502514","https://openalex.org/W2157225554","https://openalex.org/W2163668840","https://openalex.org/W2170877863","https://openalex.org/W2496263324","https://openalex.org/W2553123944","https://openalex.org/W2560387632","https://openalex.org/W2572458371","https://openalex.org/W2731507867","https://openalex.org/W2763492484","https://openalex.org/W2795810461","https://openalex.org/W2804917940","https://openalex.org/W2884872821","https://openalex.org/W2946966201","https://openalex.org/W3025765455","https://openalex.org/W4242416368"],"related_works":["https://openalex.org/W2922152683","https://openalex.org/W3009895917","https://openalex.org/W2149683435","https://openalex.org/W268268227","https://openalex.org/W2568113790","https://openalex.org/W2024993254","https://openalex.org/W4417099665","https://openalex.org/W2810522105","https://openalex.org/W2036021151","https://openalex.org/W2306321045"],"abstract_inverted_index":{"Background":[0],"The":[1],"association":[2],"of":[3,10,33,143,223,241],"antidepressant":[4,135,172,230],"medication":[5],"type":[6],"with":[7,30,68,220,227,245],"the":[8,52,92,239],"risk":[9,120,163,222],"cardiovascular":[11],"disease":[12],"(":[13,25],"CVD":[14,34,89,113,162,225,255],")":[15],"is":[16],"unclear.":[17],"We":[18,47,146],"hypothesized":[19],"that":[20],"selective":[21],"serotonin":[22],"reuptake":[23],"inhibitors":[24],"SSRI":[26,42,123,129,167,171,215,229,242,250],"s)":[27],"are":[28],"associated":[29,219],"lower":[31],"risks":[32],"events":[35,90,114],"relative":[36],"to":[37,86,111,138,254],"tricyclics":[38,246],"and":[39,45,75,104,118,157,169,203,247],"other":[40,248],"non-":[41,128,170,228,249],"antidepressants.":[43],"Methods":[44],"Results":[46],"studied":[48],"2027":[49],"participants":[50,82],"from":[51,134],"ARIC":[53],"(Atherosclerosis":[54],"Risk":[55],"in":[56,91,122,252],"Communities)":[57],"study":[58,87,93],"(mean":[59],"age":[60],"63\u00b110":[61],"years;":[62],"29%":[63],"men;":[64],"78%":[65],"white)":[66],"treated":[67],"antidepressants":[69,251],"at":[70],"some":[71],"time":[72],"between":[73],"1987":[74],"2013.":[76],"Antidepressant":[77],"usage":[78],"was":[79,164,217],"confirmed":[80],"by":[81],"bringing":[83],"pill":[84],"bottles":[85],"visits.":[88],"sample":[94],"were":[95,109,132],"identified,":[96],"including":[97],"atrial":[98,149,182],"fibrillation,":[99,150],"heart":[100,152,191],"failure,":[101,153],"myocardial":[102,155,201],"infarction,":[103],"ischemic":[105,159,212],"stroke.":[106],"Hazard":[107],"ratios":[108],"used":[110],"compare":[112],"adjusted":[115],"for":[116,140,166,181,190,200,211],"sociodemographic":[117],"clinical":[119],"factors":[121],"s":[124,168,243],"users":[125,173],"(47%)":[126],"versus":[127],"users.":[130],"Participants":[131],"followed":[133],"initiation":[136],"up":[137],"2016":[139],"a":[141],"median":[142],"13.5":[144],"years.":[145],"identified":[147],"332":[148],"365":[151],"174":[154],"infarction":[156],"119":[158],"stroke":[160],"events.":[161],"similar":[165],"(hazard":[174],"ratio,":[175,185,194,205],"1.10;":[176],"95%":[177,187,196,207],"CI":[178,197,208],",":[179,198,209],"0.86-1.41":[180],"fibrillation;":[183],"hazard":[184,193,204],"0.98;":[186],"CI,":[188],"0.77-1.25":[189],"failure;":[192],"0.91;":[195],"0.64-1.29":[199],"infarction;":[202],"1.07;":[206],"0.70-1.63":[210],"stroke).":[213],"Conclusions":[214],"use":[216,240],"not":[218,235],"reduced":[221],"incident":[224],"compared":[226,244],"use.":[231],"These":[232],"results":[233],"do":[234],"provide":[236],"evidence":[237],"supporting":[238],"relation":[253],"risk.":[256]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-06-07T00:00:00"}
