{"id":"https://openalex.org/W2946893425","doi":"https://doi.org/10.1080/14786419.2019.1610956","title":"A new monoterpene glycoside from Pedicularis verticillata and anticomplementary activity of its compounds","display_name":"A new monoterpene glycoside from Pedicularis verticillata and anticomplementary activity of its compounds","publication_year":2019,"publication_date":"2019-05-28","ids":{"openalex":"https://openalex.org/W2946893425","doi":"https://doi.org/10.1080/14786419.2019.1610956","mag":"2946893425","pmid":"https://pubmed.ncbi.nlm.nih.gov/31135212"},"language":"en","primary_location":{"id":"doi:10.1080/14786419.2019.1610956","doi":"https://doi.org/10.1080/14786419.2019.1610956","is_oa":false,"landing_page_url":"https://doi.org/10.1080/14786419.2019.1610956","pdf_url":null,"source":{"id":"https://openalex.org/S205999849","display_name":"Natural Product Research","issn_l":"1478-6419","issn":["1478-6419","1478-6427"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Natural Product Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060542920","display_name":"Yan Wang","orcid":"https://orcid.org/0000-0003-1187-9527","observed_orcids":["https://orcid.org/0000-0003-1187-9527","https://orcid.org/0000-0002-3144-8372"]},"institutions":[{"id":"https://openalex.org/I102208913","display_name":"Shihezi University","ror":"https://ror.org/04x0kvm78","country_code":"CN","type":"education","lineage":["https://openalex.org/I102208913"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yan Wang","raw_affiliation_strings":["Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, School of Pharmacy, Shihezi University, Shihezi, P. R. China;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, School of Pharmacy, Shihezi University, Shihezi, P. R. China;","institution_ids":["https://openalex.org/I102208913"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046495628","display_name":"Shao Ming-hui","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102208913","display_name":"Shihezi University","ror":"https://ror.org/04x0kvm78","country_code":"CN","type":"education","lineage":["https://openalex.org/I102208913"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ming-Hui Shao","raw_affiliation_strings":["Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, School of Pharmacy, Shihezi University, Shihezi, P. R. China;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, School of Pharmacy, Shihezi University, Shihezi, P. R. China;","institution_ids":["https://openalex.org/I102208913"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056810119","display_name":"Siwen Yuan","orcid":"https://orcid.org/0000-0003-4819-5882","observed_orcids":["https://orcid.org/0000-0003-4819-5882"]},"institutions":[{"id":"https://openalex.org/I102208913","display_name":"Shihezi University","ror":"https://ror.org/04x0kvm78","country_code":"CN","type":"education","lineage":["https://openalex.org/I102208913"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Si-Wen Yuan","raw_affiliation_strings":["Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, School of Pharmacy, Shihezi University, Shihezi, P. R. China;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, School of Pharmacy, Shihezi University, Shihezi, P. R. China;","institution_ids":["https://openalex.org/I102208913"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080449172","display_name":"Yan Lu","orcid":"https://orcid.org/0000-0002-9420-7090","observed_orcids":["https://orcid.org/0000-0002-9420-7090"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yan Lu","raw_affiliation_strings":["Department of Pharmacognosy, School of Pharmacy, Fudan University, Shanghai, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacognosy, School of Pharmacy, Fudan University, Shanghai, P. R. China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100341381","display_name":"Qi Wang","orcid":"https://orcid.org/0000-0003-3118-2866","observed_orcids":["https://orcid.org/0000-0003-3118-2866"]},"institutions":[{"id":"https://openalex.org/I102208913","display_name":"Shihezi University","ror":"https://ror.org/04x0kvm78","country_code":"CN","type":"education","lineage":["https://openalex.org/I102208913"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Qi Wang","raw_affiliation_strings":["Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, School of Pharmacy, Shihezi University, Shihezi, P. R. China;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, School of Pharmacy, Shihezi University, Shihezi, P. R. China;","institution_ids":["https://openalex.org/I102208913"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5100341381"],"corresponding_institution_ids":["https://openalex.org/I102208913"],"apc_list":null,"apc_paid":null,"fwci":1.483,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.81312574,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":92,"max":98},"biblio":{"volume":"35","issue":"1","first_page":"1","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11973","display_name":"Plant chemical constituents analysis","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pedicularis-verticillata","display_name":"Pedicularis verticillata","score":0.9940000176429749},{"id":"https://openalex.org/keywords/monoterpene-glycosides","display_name":"monoterpene glycosides","score":0.9369999766349792},{"id":"https://openalex.org/keywords/natural-product-isolation","display_name":"natural product isolation","score":0.7379999756813049},{"id":"https://openalex.org/keywords/structure-elucidation","display_name":"structure elucidation","score":0.9169999957084656},{"id":"https://openalex.org/keywords/anticomplementary-activity","display_name":"anticomplementary activity","score":0.8109999895095825},{"id":"https://openalex.org/keywords/ch50","display_name":"CH50","score":0.6700000166893005},{"id":"https://openalex.org/keywords/plant-secondary-metabolites","display_name":"plant secondary metabolites","score":0.6190000176429749}],"concepts":[{"id":"https://openalex.org/C2777671706","wikidata":"https://www.wikidata.org/wiki/Q32528","display_name":"Monoterpene","level":2,"score":0.849564790725708},{"id":"https://openalex.org/C194671627","wikidata":"https://www.wikidata.org/wiki/Q192639","display_name":"Glycoside","level":2,"score":0.7343074679374695},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.5729409456253052},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5618281364440918},{"id":"https://openalex.org/C19549132","wikidata":"https://www.wikidata.org/wiki/Q11141463","display_name":"Two-dimensional nuclear magnetic resonance spectroscopy","level":2,"score":0.416535884141922},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.2560591697692871}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003167","descriptor_name":"Complement Activation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D003169","descriptor_name":"Complement Inactivator Proteins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004353","descriptor_name":"Drug Evaluation, Preclinical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006027","descriptor_name":"Glycosides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006027","descriptor_name":"Glycosides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D032262","descriptor_name":"Pedicularis","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D039821","descriptor_name":"Monoterpenes","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D039821","descriptor_name":"Monoterpenes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1080/14786419.2019.1610956","doi":"https://doi.org/10.1080/14786419.2019.1610956","is_oa":false,"landing_page_url":"https://doi.org/10.1080/14786419.2019.1610956","pdf_url":null,"source":{"id":"https://openalex.org/S205999849","display_name":"Natural Product Research","issn_l":"1478-6419","issn":["1478-6419","1478-6427"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Natural Product Research","raw_type":"journal-article"},{"id":"pmid:31135212","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31135212","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Natural product research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G957495263","display_name":"\u7ef4\u836f\u725b\u820c\u8349\u7684\u6297\u8865\u4f53\u6d3b\u6027\u6210\u5206\u7814\u7a76","funder_award_id":"81160387","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1977416380","https://openalex.org/W1986971042","https://openalex.org/W1987219747","https://openalex.org/W1990675415","https://openalex.org/W1996139968","https://openalex.org/W2010871897","https://openalex.org/W2018215325","https://openalex.org/W2023686589","https://openalex.org/W2053464442","https://openalex.org/W2066708433","https://openalex.org/W2081055895","https://openalex.org/W2157045127","https://openalex.org/W2163417489","https://openalex.org/W2195808491","https://openalex.org/W2274120218","https://openalex.org/W2363827280","https://openalex.org/W2404478418","https://openalex.org/W2493967681","https://openalex.org/W2800205556","https://openalex.org/W2804611191","https://openalex.org/W2951395535"],"related_works":["https://openalex.org/W2800205556","https://openalex.org/W1996139968","https://openalex.org/W2388112869","https://openalex.org/W3192880727","https://openalex.org/W2274120218","https://openalex.org/W7154472744","https://openalex.org/W2549397911","https://openalex.org/W1979009086","https://openalex.org/W2315340451","https://openalex.org/W1499037058"],"abstract_inverted_index":{"A":[0],"new":[1,27],"monoterpene":[2],"glycoside":[3],"named":[4],"as":[5,31],"pedivertoside":[6],"D":[7],"(1),":[8],"together":[9],"with":[10,48,65],"13":[11],"known":[12,41],"compounds":[13,42],"(2\u201314,":[14],"resp.)":[15],"were":[16,43],"isolated":[17],"from":[18,84],"the":[19,61],"whole":[20],"plant":[21],"of":[22,68],"Pedicularis":[23],"verticillata":[24],"L.":[25],"The":[26,40],"compound":[28],"was":[29],"identified":[30],"(2E,6E,5R)-5,8-dihydrooxy-2,6-dimethyl-3,7-octadienyl-\u03b2-D-glucopyranoside":[32],"by":[33],"spectroscopic":[34],"methods":[35],"including":[36],"2":[37],"D-NMR":[38],"techniques.":[39],"determined":[44],"spectroscopically":[45],"and":[46,55,71],"compared":[47],"previously":[49],"reported":[50],"spectral":[51],"data.":[52],"Compounds":[53],"6":[54],"9":[56],"exhibited":[57],"anticomplementary":[58],"effects":[59],"against":[60],"classical":[62],"pathway":[63],"(CP)":[64],"CH50":[66],"values":[67],"0.07":[69],"mM":[70],"0.23":[72],"mM,":[73],"respectively,":[74],"which":[75],"are":[76],"plausible":[77],"candidates":[78],"for":[79],"developing":[80],"potent":[81],"anti-complementary":[82],"agents":[83],"this":[85],"plant.":[86]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-06-07T00:00:00"}