{"id":"https://openalex.org/W2945890277","doi":"https://doi.org/10.1093/jnci/djz091","title":"Is Breast Cancer in Asian and Asian American Women a Different Disease?","display_name":"Is Breast Cancer in Asian and Asian American Women a Different Disease?","publication_year":2019,"publication_date":"2019-05-07","ids":{"openalex":"https://openalex.org/W2945890277","doi":"https://doi.org/10.1093/jnci/djz091","mag":"2945890277","pmid":"https://pubmed.ncbi.nlm.nih.gov/31093671","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6910160"},"language":"en","primary_location":{"id":"doi:10.1093/jnci/djz091","doi":"https://doi.org/10.1093/jnci/djz091","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jnci/djz091","pdf_url":"https://academic.oup.com/jnci/article-pdf/111/12/1243/31963485/djz091.pdf","source":{"id":"https://openalex.org/S98010888","display_name":"JNCI Journal of the National Cancer Institute","issn_l":"0027-8874","issn":["0027-8874","1460-2105"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JNCI: Journal of the National Cancer Institute","raw_type":"journal-article"},"volume":null,"type":"editorial","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/jnci/article-pdf/111/12/1243/31963485/djz091.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085743511","display_name":"Scarlett Lin Gomez","orcid":"https://orcid.org/0000-0002-5143-4867","observed_orcids":["https://orcid.org/0000-0002-5143-4867"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Scarlett Lin Gomez","raw_affiliation_strings":["Correspondence to: Scarlett Lin Gomez, PhD, Department of Epidemiology and Biostatistics, University of California, 550 16th Street, San Francisco, CA ("],"raw_orcid":"https://orcid.org/0000-0002-5143-4867","affiliations":[{"raw_affiliation_string":"Correspondence to: Scarlett Lin Gomez, PhD, Department of Epidemiology and Biostatistics, University of California, 550 16th Street, San Francisco, CA (","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030647280","display_name":"Song Yao","orcid":"https://orcid.org/0000-0001-9442-1313","observed_orcids":["https://orcid.org/0000-0001-9442-1313"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I2803209242","display_name":"University of California System","ror":"https://ror.org/00pjdza24","country_code":"US","type":"education","lineage":["https://openalex.org/I2803209242"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Song Yao","raw_affiliation_strings":["Department of Epidemiology and Biostatistics , University of California , 550 16th Street , San Francisco , CA"],"raw_orcid":"https://orcid.org/0000-0001-9442-1313","affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics , University of California , 550 16th Street , San Francisco , CA","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I2803209242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031698839","display_name":"Lawrence H. Kushi","orcid":"https://orcid.org/0000-0001-9136-1175","observed_orcids":["https://orcid.org/0000-0001-9136-1175"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I2803209242","display_name":"University of California System","ror":"https://ror.org/00pjdza24","country_code":"US","type":"education","lineage":["https://openalex.org/I2803209242"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lawrence H Kushi","raw_affiliation_strings":["Department of Epidemiology and Biostatistics , University of California , 550 16th Street , San Francisco , CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics , University of California , 550 16th Street , San Francisco , CA","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I2803209242"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067783851","display_name":"Allison W. Kurian","orcid":"https://orcid.org/0000-0002-6175-9470","observed_orcids":["https://orcid.org/0000-0002-6175-9470"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I2803209242","display_name":"University of California System","ror":"https://ror.org/00pjdza24","country_code":"US","type":"education","lineage":["https://openalex.org/I2803209242"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Allison W Kurian","raw_affiliation_strings":["Department of Epidemiology and Biostatistics , University of California , 550 16th Street , San Francisco , CA"],"raw_orcid":"https://orcid.org/0000-0002-6175-9470","affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics , University of California , 550 16th Street , San Francisco , CA","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I2803209242"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5085743511"],"corresponding_institution_ids":["https://openalex.org/I180670191"],"apc_list":{"value":5436,"currency":"USD","value_usd":5436},"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":31,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"111","issue":"12","first_page":"1243","last_page":"1244"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10556","display_name":"Global Cancer Incidence and Screening","score":0.9437999725341797,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10556","display_name":"Global Cancer Incidence and Screening","score":0.9437999725341797,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.04659999907016754,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11134","display_name":"Breast Lesions and Carcinomas","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-cancer-incidence","display_name":"breast cancer incidence","score":0.8889999985694885},{"id":"https://openalex.org/keywords/asian-women","display_name":"Asian women","score":0.781000018119812},{"id":"https://openalex.org/keywords/asian-american-women","display_name":"Asian American women","score":0.9800000190734863},{"id":"https://openalex.org/keywords/age-specific-incidence","display_name":"age-specific incidence","score":0.8289999961853027},{"id":"https://openalex.org/keywords/triple-negative-breast-cancer","display_name":"triple-negative breast cancer","score":0.6940000057220459},{"id":"https://openalex.org/keywords/her2-positive-breast-cancer","display_name":"HER2-positive breast cancer","score":0.953000009059906},{"id":"https://openalex.org/keywords/estrogen-receptor","display_name":"estrogen receptor","score":0.7699999809265137},{"id":"https://openalex.org/keywords/progesterone-receptor","display_name":"progesterone receptor","score":0.9990000128746033},{"id":"https://openalex.org/keywords/tumor-grade","display_name":"tumor grade","score":0.7649999856948853},{"id":"https://openalex.org/keywords/breast-cancer-subtypes","display_name":"breast cancer subtypes","score":0.6790000200271606},{"id":"https://openalex.org/keywords/east-asia","display_name":"East Asia","score":0.4650000035762787},{"id":"https://openalex.org/keywords/racial-differences-in-cancer","display_name":"racial differences in cancer","score":0.4819999933242798},{"id":"https://openalex.org/keywords/birth-cohort-trends","display_name":"birth cohort trends","score":0.44600000977516174},{"id":"https://openalex.org/keywords/seer-comparison","display_name":"SEER comparison","score":0.6480000019073486},{"id":"https://openalex.org/keywords/ethnic-differences-in-cancer-risk","display_name":"ethnic differences in cancer risk","score":0.4189999997615814}],"concepts":[{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.6360776424407959},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.620037853717804},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5822727680206299},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4947185218334198},{"id":"https://openalex.org/C3019166669","wikidata":"https://www.wikidata.org/wiki/Q727928","display_name":"Asian americans","level":3,"score":0.48181334137916565},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.45040541887283325},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.32150495052337646},{"id":"https://openalex.org/C19165224","wikidata":"https://www.wikidata.org/wiki/Q23404","display_name":"Anthropology","level":1,"score":0.10735583305358887},{"id":"https://openalex.org/C137403100","wikidata":"https://www.wikidata.org/wiki/Q41710","display_name":"Ethnic group","level":2,"score":0.10681480169296265},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.10531353950500488}],"mesh":[{"descriptor_ui":"D001213","descriptor_name":"Asian","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/jnci/djz091","doi":"https://doi.org/10.1093/jnci/djz091","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jnci/djz091","pdf_url":"https://academic.oup.com/jnci/article-pdf/111/12/1243/31963485/djz091.pdf","source":{"id":"https://openalex.org/S98010888","display_name":"JNCI Journal of the National Cancer Institute","issn_l":"0027-8874","issn":["0027-8874","1460-2105"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JNCI: Journal of the National Cancer Institute","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6910160","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6910160","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Natl Cancer Inst","raw_type":"Text"},{"id":"pmid:31093671","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31093671","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the National Cancer Institute","raw_type":"Editorial"}],"best_oa_location":{"id":"doi:10.1093/jnci/djz091","doi":"https://doi.org/10.1093/jnci/djz091","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jnci/djz091","pdf_url":"https://academic.oup.com/jnci/article-pdf/111/12/1243/31963485/djz091.pdf","source":{"id":"https://openalex.org/S98010888","display_name":"JNCI Journal of the National Cancer Institute","issn_l":"0027-8874","issn":["0027-8874","1460-2105"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JNCI: Journal of the National Cancer Institute","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9907000064849854,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"},{"score":0.7578999996185303,"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2945890277.pdf","grobid_xml":"https://content.openalex.org/works/W2945890277.grobid-xml"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W1999452613","https://openalex.org/W2016538479","https://openalex.org/W2017834566","https://openalex.org/W2070734492","https://openalex.org/W2088210143","https://openalex.org/W2098123437","https://openalex.org/W2123618524","https://openalex.org/W2154217658","https://openalex.org/W2159427817","https://openalex.org/W2283351472","https://openalex.org/W2597950457","https://openalex.org/W2762472378","https://openalex.org/W2804413675","https://openalex.org/W2893632651","https://openalex.org/W2911818569","https://openalex.org/W2936876638","https://openalex.org/W2938370698","https://openalex.org/W2946519987"],"related_works":["https://openalex.org/W2946519987","https://openalex.org/W3141928128","https://openalex.org/W4406775023","https://openalex.org/W2086062849","https://openalex.org/W7159683096","https://openalex.org/W2123618524","https://openalex.org/W3004918284","https://openalex.org/W4409630568","https://openalex.org/W2033455960","https://openalex.org/W3094594795"],"abstract_inverted_index":{"In":[0],"this":[1,578,802,931],"issue,":[2],"Lin":[3,356,588],"et":[4,357,589],"al.":[5,358,590],"(1)":[6],"compared":[7,47,108,305],"age-specific":[8,99,153,214,368,393,462,501,827],"breast":[9,119,197,272,289,396,414,460,487,499,531,653,740,764,778,830,960,969,1008],"cancer":[10,13,120,198,273,397,415,461,470,500,519,624,654,724,765,779,831,961,970,1009],"incidence":[11,100,121,162,180,199,560,780,846],"using":[12],"registry":[14],"data":[15,80,919],"from":[16,81,349,355,920,975,1097],"several":[17,82],"East":[18,143,377],"Asian":[19,84,106,115,144,201,251,326,378,545,633,743,758,791,869,881,898,956,1012,1014],"countries":[20,379,759,775],"(Hong":[21],"Kong,":[22],"Japan,":[23],"Korea,":[24],"Taiwan,":[25,407],"Singapore,":[26,408],"and":[27,30,37,70,72,86,92,101,129,207,223,248,267,283,291,336,380,409,421,433,479,488,527,544,572,605,611,632,639,722,744,747,789,814,823,834,847,850,916,925,955,1013,1023,1078,1081],"China":[28],"[Shanghai])":[29],"the":[31,42,87,105,114,124,152,178,182,210,235,240,381,456,459,483,498,617,649,684,689,723,736,770,821,840,922,950,965,1004],"National":[32],"Cancer":[33,663,709,1036,1048,1060],"Institute\u2019s":[34],"Surveillance,":[35],"Epidemiology,":[36,91],"End":[38,93],"Results":[39,94],"Program":[40],"in":[41,148,181,194,221,303,334,376,431,581,594,623,644,655,698,757,769,787,790,804,808,826,866,990],"United":[43,88,382,771,923],"States.":[44],"They":[45,96],"also":[46,253,313,354,872],"case":[48,241],"distributions":[49,242],"of":[50,126,243,265,270,281,286,363,395,429,535,539,564,596,613,619,652,673,679,695,718,739,820,829,860,878,953,968,1003,1007,1018,1021,1026,1039,1051,1066,1076,1084],"pathological":[51,525],"characteristics":[52,256],"(estrogen":[53],"receptor":[54,57],"[ER];":[55],"progesterone":[56],"[PR];":[58],"human":[59],"epidermal":[60],"growth":[61],"factor":[62],"2":[63],"[HER2];":[64],"subtypes":[65],"based":[66,351,481],"on":[67,352,482,801],"ER,":[68,244],"PR,":[69,245],"HER2;":[71],"grade":[73,75,249,292],"[specifically":[74],"3])":[76],"between":[77,217,330,374,427,688,742],"Asia":[78,222,304,335,432,788,926],"(using":[79],"large":[83],"hospitals)":[85],"States":[89,383,772,924],"(Surveillance,":[90],"data).":[95],"found":[97,212],"distinct":[98],"clinico-pathological":[102],"patterns":[103,215,324,343,369,417,463,465,485,828,849,1006],"among":[104,156,200,301,308,325,387,418,542,630,636,785,868,880,894,907,913,938,949,1011],"populations":[107],"with":[109,133,139,165,177,228,306,323,346,464,477,505,515,552,667,857,884],"US":[110,157,224,337,401,554,914],"data.":[111],"Specifically,":[112],"across":[113],"countries,":[116],"contemporary":[117],"(2011\u20132014)":[118],"peaked":[122],"during":[123],"ages":[125],"45\u201349":[127],"years":[128,171,189,983],"either":[130],"declined":[131],"thereafter":[132],"age":[134,140,166,169,174,186,232,236,416,686,904,967,981,985],"(Japan,":[135],"Korea)":[136],"or":[137,592,773],"stabilized":[138],"(all":[141],"other":[142,321,637,1103],"countries).":[145],"This":[146],"is":[147,472,494,550,627,944,997],"stark":[149],"contrast":[150],"to":[151,172,184,258,317,425,444,449,474,496,600,734,748,929,946,999],"pattern":[154],"observed":[155,568],"non-Hispanic":[158,225,259,309,338,402,434,548],"white":[159,226,260,310,339,403,745],"women,":[160,227,261,404,883],"where":[161,392],"increases":[163],"exponentially":[164],"beginning":[167],"around":[168,173],"40":[170],"80":[175],"years,":[176],"highest":[179],"75-":[183],"79-year-old":[185],"group,":[187],"30":[188],"older":[190,296,669],"than":[191,320,384,530,547,707,767,896,980],"for":[192,204,219,332,400,406,452,466,486,570,843,986],"women":[193,220,252,302,311,328,333,375,430,574,746,768,786,793,870,900],"Asia.":[195],"Examining":[196],"Americans,":[202],"specifically":[203,262],"Chinese,":[205,419],"Japanese,":[206,420],"Koreans":[208],"(2),":[209],"authors":[211,457,1104],"that":[213,367,440,471,491,612,616],"were":[216,312,567,676,681],"those":[218,307,331,399,428],"a":[229,275,536,645,656,671,702,876],"slightly":[230],"later":[231],"peak":[233],"(in":[234],"60":[237],"decade).":[238],"Comparing":[239],"HER2,":[246],"subtypes,":[247,322],"III,":[250],"exhibited":[254],"unique":[255,599,1005],"relative":[257],"higher":[263,284,537,562,716,892,936],"proportions":[264,269,280,285],"ER+":[266,282],"lower":[268,279,763],"triple-negative":[271,288],"at":[274,295,905],"younger":[276],"age,":[277,696],"but":[278],"HER2+,":[287],"cancer,":[290,468,490,507],"3":[293],"tumors":[294,541,697,741],"ages.":[297],"Breast":[298],"cancers":[299,566],"diagnosed":[300],"proportionally":[314],"more":[315,372,388,668,703],"likely":[316,934],"be":[318,371,450,513,873],"HER2+":[319,540],"American":[327,792,882,899,1015],"again":[329],"women.":[340,1016],"These":[341],"pan-Asian":[342],"are":[344,446,732],"consistent":[345,551],"previous":[347,553],"results":[348],"Taiwan":[350],"publications":[353],"(3,4).":[359],"However,":[360,455,576,777],"longitudinal":[361],"analyses":[362],"birth":[364,390],"cohorts":[365,391,691],"show":[366],"may":[370,752,817,837,851,871,973],"similar":[373,629],"expected,":[385],"especially":[386,405],"recent":[389,646,886,939],"rates":[394,563],"exceed":[398],"South":[410],"Korea":[411],"(5).":[412],"As":[413],"Korean":[422,658,699],"Americans":[423,546,634,957],"appear":[424],"fall":[426],"whites":[435,549],"(1),":[436,591],"it":[437],"would":[438],"follow":[439],"lifestyle":[441,475],"factors":[442,598,841],"related":[443],"Westernization":[445,492],"strongly":[447],"suspected":[448],"responsible":[451,842],"these":[453,805,844],"patterns.":[454,502],"contrasted":[458],"colorectal":[467,489,506,518],"another":[469],"vulnerable":[473],"changes":[476,825],"Westernization,":[478],"concluded,":[480],"contrasting":[484],"alone":[493],"unlikely":[495],"explain":[497],"The":[503,533,662,708,863,902],"comparison":[504],"while":[508],"an":[509,796],"interesting":[510],"approach,":[511],"should":[512],"interpreted":[514],"caution,":[516],"because":[517],"has":[520,781,909],"obviously":[521],"different":[522],"risk":[523,597,766,848,854,867,879,893,937,962,1010],"factors,":[524,855],"characteristics,":[526],"screening":[528,978,989],"approaches":[529],"cancer.":[532],"observation":[534],"proportion":[538],"Asians":[543,631,908,954,972],"studies":[555,731,836],"(6\u20138),":[556],"although":[557],"when":[558],"considering":[559],"rates,":[561],"HR+":[565],"only":[569],"Filipina":[571],"Vietnamese":[573],"(8).":[575],"whether":[577,750],"reflects":[579,935],"differences":[580,593,675,687],"underlying":[582],"disease":[583,803],"biology,":[584],"as":[585,635,713,856],"proposed":[586],"by":[587,683,715],"prevalence":[595],"each":[601],"subtype":[602],"remains":[603],"inconclusive":[604],"deserves":[606],"further":[607],"study.":[608],"Our":[609],"work":[610],"others":[614],"suggests":[615],"spectrum":[618],"inherited":[620],"pathogenic":[621],"variants":[622],"susceptibility":[625],"genes":[626],"fairly":[628],"racial":[638],"ethnic":[640],"groups":[641],"(9\u201311).":[642],"Nevertheless,":[643],"study":[647,889],"comparing":[648],"molecular":[650,674,737],"landscape":[651,738],"young":[657],"patient":[659],"population":[660,666],"vs":[661],"Genome":[664,710],"Atlas":[665,711],"cases,":[670,712],"number":[672],"identified,":[677],"most":[678],"which":[680,933],"driven":[682],"striking":[685],"two":[690],"(12).":[692],"Interestingly,":[693],"independent":[694],"patients":[700],"had":[701,762],"active":[704],"immune":[705],"microenvironment":[706],"evidenced":[714],"expression":[717],"cytotoxic":[719],"T-cell":[720],"markers":[721],"immunotherapy":[725],"target":[726],"PD-L1.":[727],"Further":[728],"tumor":[729],"genomic":[730],"needed":[733,998],"characterize":[735],"ascertain":[749],"they":[751],"have":[753,760,927],"clinical":[754],"implications.":[755],"Women":[756],"historically":[761],"European":[774],"(13).":[776],"been":[782,911],"increasing":[783],"rapidly":[784],"(2,5,8),":[794],"warranting":[795],"urgent":[797],"increased":[798],"research":[799,996,1095],"focus":[800],"populations.":[806],"Changes":[807],"reproductive":[809],"patterns,":[810],"obesity,":[811],"food":[812],"intake,":[813],"physical":[815],"activity":[816],"underlie":[818],"some":[819,991],"temporal":[822],"geographic":[824],"risk.":[832],"Cross-national":[833],"multi-generational":[835],"help":[838],"elucidate":[839],"dynamic":[845],"uncover":[852],"novel":[853],"earlier":[858,903,966,979],"generations":[859],"migrant":[861],"studies.":[862],"rapid":[864],"shift":[865],"translating":[874],"into":[875],"reversal":[877],"our":[885],"pilot":[887],"case-control":[888],"demonstrating":[890],"surprisingly":[891],"foreign-born":[895],"US-born":[897],"(14).":[901],"onset":[906],"long":[910],"noted":[912],"clinicians,":[915],"now":[917],"empirical":[918],"both":[921],"accumulated":[928],"support":[930],"observation,":[932],"cohorts.":[940],"Public":[941],"health":[942],"outreach":[943],"necessary":[945],"increase":[947],"awareness":[948],"general":[951],"public":[952],"regarding":[958],"their":[959],"(15).":[963],"Given":[964],"onset,":[971],"benefit":[974],"starting":[976,987],"mammographic":[977],"50":[982],"[the":[984],"routine":[988],"practice":[992],"guidelines":[993],"(16,17)].":[994],"Additional":[995],"guide":[1000],"effective":[1001],"management":[1002],"Affiliations":[1017],"authors:":[1019],"Department":[1020],"Epidemiology":[1022],"Biostatistics,":[1024],"University":[1025,1038,1050],"California,":[1027,1040,1052,1071],"San":[1028,1041,1053],"Francisco,":[1029,1042,1054],"CA":[1030,1043,1055,1073,1089],"(SLG);":[1031,1044,1056],"Helen":[1032],"Diller":[1033],"Family":[1034],"Comprehensive":[1035,1059],"Center,":[1037,1061],"Greater":[1045],"Bay":[1046],"Area":[1047],"Registry,":[1049],"Roswell":[1057],"Park":[1058],"Buffalo,":[1062],"NY":[1063],"(SY);":[1064],"Division":[1065],"Research,":[1067],"Kaiser":[1068],"Permanente":[1069],"Northern":[1070],"Oakland,":[1072],"(LHK);":[1074],"Departments":[1075],"Medicine":[1077],"Health":[1079],"Research":[1080],"Policy,":[1082],"School":[1083],"Medicine,":[1085],"Stanford":[1086,1100],"University,":[1087],"Stanford,":[1088],"(AWK).":[1090],"Dr":[1091],"Kurian":[1092],"reports":[1093],"receiving":[1094],"funding":[1096],"Myriad,":[1098],"through":[1099],"University.":[1101],"All":[1102],"report":[1105],"no":[1106],"disclosures.":[1107]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-05-29T00:00:00"}