{"id":"https://openalex.org/W2945414031","doi":"https://doi.org/10.3390/cancers11050694","title":"New Insights into Molecular Oncogenesis and Therapy of Uveal Melanoma","display_name":"New Insights into Molecular Oncogenesis and Therapy of Uveal Melanoma","publication_year":2019,"publication_date":"2019-05-19","ids":{"openalex":"https://openalex.org/W2945414031","doi":"https://doi.org/10.3390/cancers11050694","mag":"2945414031","pmid":"https://pubmed.ncbi.nlm.nih.gov/31109147","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6562554"},"language":"en","primary_location":{"id":"doi:10.3390/cancers11050694","doi":"https://doi.org/10.3390/cancers11050694","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/cancers11050694","pdf_url":"https://www.mdpi.com/2072-6694/11/5/694/pdf?version=1558260481","source":{"id":"https://openalex.org/S168415115","display_name":"Cancers","issn_l":"2072-6694","issn":["2072-6694"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancers","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2072-6694/11/5/694/pdf?version=1558260481","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053274364","display_name":"Sara Silvia Violanti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201324441","display_name":"University of Ferrara","ror":"https://ror.org/041zkgm14","country_code":"IT","type":"education","lineage":["https://openalex.org/I201324441"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Sara Violanti","raw_affiliation_strings":["Department of Biomedical Sciences and Specialized Surgeries, School of Medicine, University of Ferrara and Eye Unit of University Hospital of Ferrara, 44124 Ferrara, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences and Specialized Surgeries, School of Medicine, University of Ferrara and Eye Unit of University Hospital of Ferrara, 44124 Ferrara, Italy","institution_ids":["https://openalex.org/I201324441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025436324","display_name":"Ilaria Bononi","orcid":"https://orcid.org/0000-0002-5286-5845","observed_orcids":["https://orcid.org/0000-0002-5286-5845"]},"institutions":[{"id":"https://openalex.org/I201324441","display_name":"University of Ferrara","ror":"https://ror.org/041zkgm14","country_code":"IT","type":"education","lineage":["https://openalex.org/I201324441"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Ilaria Bononi","raw_affiliation_strings":["Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, School of Medicine, University of Ferrara, 44121 Ferrara, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, School of Medicine, University of Ferrara, 44121 Ferrara, Italy","institution_ids":["https://openalex.org/I201324441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086971584","display_name":"Carla Enrica Gallenga","orcid":"https://orcid.org/0000-0002-7426-8603","observed_orcids":["https://orcid.org/0000-0002-7426-8603"]},"institutions":[{"id":"https://openalex.org/I201324441","display_name":"University of Ferrara","ror":"https://ror.org/041zkgm14","country_code":"IT","type":"education","lineage":["https://openalex.org/I201324441"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Carla Gallenga","raw_affiliation_strings":["Department of Biomedical Sciences and Specialized Surgeries, School of Medicine, University of Ferrara and Eye Unit of University Hospital of Ferrara, 44124 Ferrara, Italy"],"raw_orcid":"https://orcid.org/0000-0002-7426-8603","affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences and Specialized Surgeries, School of Medicine, University of Ferrara and Eye Unit of University Hospital of Ferrara, 44124 Ferrara, Italy","institution_ids":["https://openalex.org/I201324441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000134199","display_name":"Fernanda Martini","orcid":"https://orcid.org/0000-0001-9137-0805","observed_orcids":["https://orcid.org/0000-0001-9137-0805"]},"institutions":[{"id":"https://openalex.org/I201324441","display_name":"University of Ferrara","ror":"https://ror.org/041zkgm14","country_code":"IT","type":"education","lineage":["https://openalex.org/I201324441"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Fernanda Martini","raw_affiliation_strings":["Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, School of Medicine, University of Ferrara, 44121 Ferrara, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, School of Medicine, University of Ferrara, 44121 Ferrara, Italy","institution_ids":["https://openalex.org/I201324441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012256814","display_name":"Mauro G. Tognon","orcid":"https://orcid.org/0000-0001-8269-7937","observed_orcids":["https://orcid.org/0000-0001-8269-7937"]},"institutions":[{"id":"https://openalex.org/I201324441","display_name":"University of Ferrara","ror":"https://ror.org/041zkgm14","country_code":"IT","type":"education","lineage":["https://openalex.org/I201324441"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Mauro Tognon","raw_affiliation_strings":["Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, School of Medicine, University of Ferrara, 44121 Ferrara, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, School of Medicine, University of Ferrara, 44121 Ferrara, Italy","institution_ids":["https://openalex.org/I201324441"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062224908","display_name":"Paolo Perri","orcid":"https://orcid.org/0000-0003-4652-9842","observed_orcids":["https://orcid.org/0000-0003-4652-9842"]},"institutions":[{"id":"https://openalex.org/I201324441","display_name":"University of Ferrara","ror":"https://ror.org/041zkgm14","country_code":"IT","type":"education","lineage":["https://openalex.org/I201324441"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Paolo Perri","raw_affiliation_strings":["Department of Biomedical Sciences and Specialized Surgeries, School of Medicine, University of Ferrara and Eye Unit of University Hospital of Ferrara, 44124 Ferrara, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences and Specialized Surgeries, School of Medicine, University of Ferrara and Eye Unit of University Hospital of Ferrara, 44124 Ferrara, Italy","institution_ids":["https://openalex.org/I201324441"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5012256814","https://openalex.org/A5062224908"],"corresponding_institution_ids":["https://openalex.org/I201324441"],"apc_list":{"value":1800,"currency":"CHF","value_usd":1824},"apc_paid":{"value":1800,"currency":"CHF","value_usd":1824},"fwci":0.9256,"has_fulltext":true,"cited_by_count":34,"citation_normalized_percentile":{"value":0.62162162,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"11","issue":"5","first_page":"694","last_page":"694"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11328","display_name":"Ocular Oncology and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11328","display_name":"Ocular Oncology and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11149","display_name":"Veterinary Oncology Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11194","display_name":"Ocular Diseases and Beh\u00e7et\u2019s Syndrome","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/uveal-melanoma","display_name":"uveal melanoma","score":1.0},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.6169999837875366},{"id":"https://openalex.org/keywords/therapeutic-target","display_name":"therapeutic target","score":0.6129999756813049},{"id":"https://openalex.org/keywords/epigenetics","display_name":"epigenetics","score":0.8190000057220459},{"id":"https://openalex.org/keywords/tumor-immunology","display_name":"tumor immunology","score":0.9110000133514404},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.6639999747276306},{"id":"https://openalex.org/keywords/adjuvant-therapy","display_name":"adjuvant therapy","score":0.9120000004768372},{"id":"https://openalex.org/keywords/eye-cancer","display_name":"eye cancer","score":0.5239999890327454},{"id":"https://openalex.org/keywords/molecular-pathways","display_name":"molecular pathways","score":0.4690000116825104}],"concepts":[{"id":"https://openalex.org/C2777658100","wikidata":"https://www.wikidata.org/wiki/Q180614","display_name":"Melanoma","level":2,"score":0.8707641363143921},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5778322815895081},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5675984025001526},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.5256544351577759},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.523269534111023},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.522940993309021},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.49101829528808594},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.43513837456703186},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.38055121898651123},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.36908501386642456},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3256763517856598},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2651114761829376},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.256296843290329},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2515173554420471},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.24610507488250732},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10201379656791687}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.3390/cancers11050694","doi":"https://doi.org/10.3390/cancers11050694","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/cancers11050694","pdf_url":"https://www.mdpi.com/2072-6694/11/5/694/pdf?version=1558260481","source":{"id":"https://openalex.org/S168415115","display_name":"Cancers","issn_l":"2072-6694","issn":["2072-6694"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancers","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5546110","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6562554","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6562554","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6562554","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancers (Basel)","raw_type":"Text"},{"id":"pmid:31109147","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31109147","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancers","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:a88867bf5e514d718a82652ef4a0468e","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/a88867bf5e514d718a82652ef4a0468e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cancers, Vol 11, Iss 5, p 694 (2019)","raw_type":"article"},{"id":"pmh:oai:sfera.unife.it:11392/2409444","doi":null,"is_oa":true,"landing_page_url":"https://www.mdpi.com/2072-6694/11/5/694","pdf_url":null,"source":{"id":"https://openalex.org/S4306400369","display_name":"Institutional Research Information System University of Ferrara (University of Ferrara)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I201324441","host_organization_name":"University of Ferrara","host_organization_lineage":["https://openalex.org/I201324441"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.3390/cancers11050694","doi":"https://doi.org/10.3390/cancers11050694","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/cancers11050694","pdf_url":"https://www.mdpi.com/2072-6694/11/5/694/pdf?version=1558260481","source":{"id":"https://openalex.org/S168415115","display_name":"Cancers","issn_l":"2072-6694","issn":["2072-6694"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancers","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3142538208","display_name":null,"funder_award_id":"IG21617","funder_id":"https://openalex.org/F4320323054","funder_display_name":"Associazione Italiana per la Ricerca sul Cancro"},{"id":"https://openalex.org/G5157338115","display_name":null,"funder_award_id":"IG 21617","funder_id":"https://openalex.org/F4320324162","funder_display_name":"Universit\u00e0 degli Studi di Ferrara"},{"id":"https://openalex.org/G5666337177","display_name":null,"funder_award_id":"21617","funder_id":"https://openalex.org/F4320323054","funder_display_name":"Associazione Italiana per la Ricerca sul Cancro"}],"funders":[{"id":"https://openalex.org/F4320323054","display_name":"Associazione Italiana per la Ricerca sul Cancro","ror":"https://ror.org/02g2x7380"},{"id":"https://openalex.org/F4320324162","display_name":"Universit\u00e0 degli Studi di Ferrara","ror":"https://ror.org/041zkgm14"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2945414031.pdf","grobid_xml":"https://content.openalex.org/works/W2945414031.grobid-xml"},"referenced_works_count":192,"referenced_works":["https://openalex.org/W43835372","https://openalex.org/W135866504","https://openalex.org/W154704142","https://openalex.org/W1487654146","https://openalex.org/W1503992437","https://openalex.org/W1508871122","https://openalex.org/W1571321178","https://openalex.org/W1591974336","https://openalex.org/W1700205903","https://openalex.org/W1873213319","https://openalex.org/W1964585811","https://openalex.org/W1965790374","https://openalex.org/W1967839477","https://openalex.org/W1973374541","https://openalex.org/W1974715203","https://openalex.org/W1975679429","https://openalex.org/W1975719619","https://openalex.org/W1979233636","https://openalex.org/W1980664511","https://openalex.org/W1982750833","https://openalex.org/W1983433202","https://openalex.org/W1984384698","https://openalex.org/W1984410398","https://openalex.org/W1986302429","https://openalex.org/W1986664673","https://openalex.org/W1988280154","https://openalex.org/W1990597378","https://openalex.org/W1990675339","https://openalex.org/W1991401350","https://openalex.org/W1991933930","https://openalex.org/W1995936852","https://openalex.org/W2000255330","https://openalex.org/W2004830420","https://openalex.org/W2005071089","https://openalex.org/W2009401382","https://openalex.org/W2010144136","https://openalex.org/W2013658947","https://openalex.org/W2013999805","https://openalex.org/W2014149465","https://openalex.org/W2014344989","https://openalex.org/W2017118651","https://openalex.org/W2017753274","https://openalex.org/W2018032989","https://openalex.org/W2019432751","https://openalex.org/W2020216122","https://openalex.org/W2020862957","https://openalex.org/W2028976805","https://openalex.org/W2029631449","https://openalex.org/W2033668318","https://openalex.org/W2038434969","https://openalex.org/W2040316953","https://openalex.org/W2042919532","https://openalex.org/W2043968939","https://openalex.org/W2046009884","https://openalex.org/W2046557593","https://openalex.org/W2049553585","https://openalex.org/W2053827996","https://openalex.org/W2054826402","https://openalex.org/W2055835855","https://openalex.org/W2055908412","https://openalex.org/W2057802075","https://openalex.org/W2058390096","https://openalex.org/W2060892513","https://openalex.org/W2061370536","https://openalex.org/W2062289724","https://openalex.org/W2063149848","https://openalex.org/W2063160005","https://openalex.org/W2064658787","https://openalex.org/W2067102955","https://openalex.org/W2067950281","https://openalex.org/W2069021668","https://openalex.org/W2069926898","https://openalex.org/W2071818162","https://openalex.org/W2072284395","https://openalex.org/W2073433320","https://openalex.org/W2077517114","https://openalex.org/W2082838887","https://openalex.org/W2086476949","https://openalex.org/W2089227973","https://openalex.org/W2091174084","https://openalex.org/W2092622990","https://openalex.org/W2097563467","https://openalex.org/W2097995306","https://openalex.org/W2098835477","https://openalex.org/W2098949384","https://openalex.org/W2099293633","https://openalex.org/W2100403180","https://openalex.org/W2104885590","https://openalex.org/W2107109105","https://openalex.org/W2109536183","https://openalex.org/W2111153762","https://openalex.org/W2112121482","https://openalex.org/W2113758409","https://openalex.org/W2114747879","https://openalex.org/W2115571017","https://openalex.org/W2117483786","https://openalex.org/W2123363005","https://openalex.org/W2123968827","https://openalex.org/W2128035403","https://openalex.org/W2130256950","https://openalex.org/W2132923173","https://openalex.org/W2135227685","https://openalex.org/W2139305660","https://openalex.org/W2139582991","https://openalex.org/W2140312356","https://openalex.org/W2140601334","https://openalex.org/W2143091201","https://openalex.org/W2143187571","https://openalex.org/W2143878396","https://openalex.org/W2147450167","https://openalex.org/W2153642831","https://openalex.org/W2154449652","https://openalex.org/W2157070790","https://openalex.org/W2158860287","https://openalex.org/W2160206006","https://openalex.org/W2160706109","https://openalex.org/W2160903712","https://openalex.org/W2163573227","https://openalex.org/W2165636771","https://openalex.org/W2167255026","https://openalex.org/W2169392527","https://openalex.org/W2170447375","https://openalex.org/W2187237125","https://openalex.org/W2204457581","https://openalex.org/W2217683734","https://openalex.org/W2236717787","https://openalex.org/W2280440990","https://openalex.org/W2281707699","https://openalex.org/W2290463785","https://openalex.org/W2300492004","https://openalex.org/W2311959388","https://openalex.org/W2313104165","https://openalex.org/W2314964805","https://openalex.org/W2320786076","https://openalex.org/W2330613226","https://openalex.org/W2341757648","https://openalex.org/W2342956596","https://openalex.org/W2343512379","https://openalex.org/W2343997050","https://openalex.org/W2397191612","https://openalex.org/W2413340136","https://openalex.org/W2418450403","https://openalex.org/W2418605449","https://openalex.org/W2482893243","https://openalex.org/W2499451571","https://openalex.org/W2515516401","https://openalex.org/W2516337088","https://openalex.org/W2522637881","https://openalex.org/W2529290840","https://openalex.org/W2559127842","https://openalex.org/W2560367415","https://openalex.org/W2562156357","https://openalex.org/W2572174216","https://openalex.org/W2582283428","https://openalex.org/W2590536177","https://openalex.org/W2592894172","https://openalex.org/W2596814862","https://openalex.org/W2604931745","https://openalex.org/W2608198193","https://openalex.org/W2622954972","https://openalex.org/W2624443164","https://openalex.org/W2624817404","https://openalex.org/W2724366277","https://openalex.org/W2727714870","https://openalex.org/W2740604052","https://openalex.org/W2744470342","https://openalex.org/W2745658163","https://openalex.org/W2760275069","https://openalex.org/W2762575363","https://openalex.org/W2765763382","https://openalex.org/W2766858993","https://openalex.org/W2769693481","https://openalex.org/W2796737583","https://openalex.org/W2799492638","https://openalex.org/W2802594008","https://openalex.org/W2811174604","https://openalex.org/W2890614082","https://openalex.org/W2911390717","https://openalex.org/W2913613732","https://openalex.org/W2967689081","https://openalex.org/W2978787583","https://openalex.org/W2982043178","https://openalex.org/W3015566358","https://openalex.org/W3033585083","https://openalex.org/W3048662031","https://openalex.org/W4206395947","https://openalex.org/W4211028998","https://openalex.org/W4239418290","https://openalex.org/W4246861154","https://openalex.org/W4285719527","https://openalex.org/W6629035060","https://openalex.org/W6680091864"],"related_works":["https://openalex.org/W3093671550","https://openalex.org/W2018172717","https://openalex.org/W3033585083","https://openalex.org/W2307531121","https://openalex.org/W2073998562","https://openalex.org/W2157151684","https://openalex.org/W1971366285","https://openalex.org/W1970838344","https://openalex.org/W4211028998","https://openalex.org/W4313481999"],"abstract_inverted_index":{"Uveal":[0,57],"melanoma":[1,92,116,129,184],"(UM),":[2],"which":[3],"is":[4],"the":[5,10,21,41,54,66,82,118,121,125,153,158,165],"most":[6],"common":[7],"cancer":[8],"of":[9,23,44,65,84,102,117,127,155,161],"eye,":[11],"was":[12,31],"investigated":[13],"in":[14,20,53,68,80,124,135,169,182],"recent":[15,63],"years":[16],"by":[17],"many":[18],"teams":[19],"field":[22],"biomedical":[24],"sciences":[25],"and":[26,76,87,94,106,164],"eye":[27,70],"clinicians.":[28],"New":[29],"knowledge":[30,160],"acquired":[32],"on":[33],"molecular":[34],"pathways":[35,89],"found":[36],"to":[37,107,112,147],"be":[38],"dysregulated":[39],"during":[40,90],"multistep":[42],"process":[43],"oncogenesis,":[45],"whereas":[46],"novel":[47,192],"therapeutic":[48,110,193],"approaches":[49],"gave":[50],"significant":[51],"results":[52,167],"clinical":[55,170],"applications.":[56],"melanoma-affected":[58],"patients":[59],"greatly":[60],"benefited":[61],"from":[62],"advances":[64,122],"research":[67],"this":[69,114,162],"cancer.":[71],"Tumour":[72],"biology,":[73],"genetics,":[74],"epigenetics":[75],"immunology":[77],"contributed":[78],"significantly":[79],"elucidating":[81],"role":[83],"different":[85,179],"genes":[86,105],"related":[88],"uveal":[91,137,183],"onset/progression":[93,185],"UM":[95],"treatments.":[96],"Indeed,":[97],"these":[98],"investigations":[99],"allowed":[100],"identification":[101],"new":[103,109],"target":[104],"develop":[108],"strategies/compounds":[111],"cure":[113],"aggressive":[115],"eye.":[119],"Unfortunately,":[120],"reported":[123],"treatment":[126],"cutaneous":[128],"have":[130],"not":[131],"produced":[132],"analogous":[133],"benefits":[134],"metastatic":[136],"melanoma.":[138],"Nowadays,":[139],"no":[140],"systemic":[141],"adjuvant":[142],"therapy":[143],"has":[144],"been":[145],"shown":[146],"improve":[148],"overall":[149],"survival":[150],"or":[151],"reduce":[152],"risk":[154],"metastasis.":[156],"However,":[157],"increasing":[159],"disease,":[163],"encouraging":[166],"seen":[168],"trials,":[171],"offer":[172],"promise":[173],"for":[174],"future":[175],"effective":[176],"therapies.":[177],"Herein,":[178],"pathways/genes":[180],"involved":[181],"were":[186],"taken":[187],"into":[188],"consideration,":[189],"together":[190],"with":[191],"approaches.":[194]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":2}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2019-05-29T00:00:00"}
