{"id":"https://openalex.org/W2944749961","doi":"https://doi.org/10.1016/s0016-5085(19)39279-0","title":"Mo2016 \u2013 The TGF-\u03b2/Smad3 Adaptor Sptbn1 and Aldh2 Suppress Hepatic Steatosis and Obesity","display_name":"Mo2016 \u2013 The TGF-\u03b2/Smad3 Adaptor Sptbn1 and Aldh2 Suppress Hepatic Steatosis and Obesity","publication_year":2019,"publication_date":"2019-05-01","ids":{"openalex":"https://openalex.org/W2944749961","doi":"https://doi.org/10.1016/s0016-5085(19)39279-0","mag":"2944749961"},"language":"en","primary_location":{"id":"doi:10.1016/s0016-5085(19)39279-0","doi":"https://doi.org/10.1016/s0016-5085(19)39279-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0016-5085(19)39279-0","pdf_url":null,"source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054498115","display_name":"Shuyun Rao","orcid":"https://orcid.org/0000-0002-1073-6682","observed_orcids":["https://orcid.org/0000-0002-1073-6682"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shuyun Rao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016716959","display_name":"Sobia Zaidi","orcid":"https://orcid.org/0000-0003-0289-6413","observed_orcids":["https://orcid.org/0000-0003-0289-6413"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sobia Zaidi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027961631","display_name":"Jon C. White","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jon White","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102841128","display_name":"Bibhuti Mishra","orcid":"https://orcid.org/0000-0001-5302-2447","observed_orcids":["https://orcid.org/0000-0001-5302-2447"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bibhuti Mishra","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011759459","display_name":"Patricia S. Latham","orcid":"https://orcid.org/0000-0003-2782-9444","observed_orcids":["https://orcid.org/0000-0003-2782-9444"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Patricia Latham","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5091703176","display_name":"Lopa Mishra","orcid":"https://orcid.org/0000-0002-6850-0808","observed_orcids":["https://orcid.org/0000-0002-6850-0808"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lopa Mishra","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"156","issue":"6","first_page":"S","last_page":"926"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11465","display_name":"Drug-Induced Hepatotoxicity and Protection","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sptbn1","display_name":"SPTBN1","score":0.7570000290870667},{"id":"https://openalex.org/keywords/aldh2","display_name":"ALDH2","score":0.9570000171661377},{"id":"https://openalex.org/keywords/tgf-beta-smad3-signaling","display_name":"TGF-\u03b2/Smad3 signaling","score":0.8529999852180481},{"id":"https://openalex.org/keywords/hepatic-steatosis","display_name":"hepatic steatosis","score":0.968999981880188},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.9409999847412109},{"id":"https://openalex.org/keywords/non-alcoholic-steatohepatitis","display_name":"nonalcoholic steatohepatitis","score":0.9139999747276306},{"id":"https://openalex.org/keywords/ursodeoxycholic-acid","display_name":"ursodeoxycholic acid","score":0.6000000238418579},{"id":"https://openalex.org/keywords/farnesoid-x-receptor","display_name":"farnesoid X receptor","score":0.4059999883174896},{"id":"https://openalex.org/keywords/tgr5","display_name":"TGR5","score":0.9629999995231628},{"id":"https://openalex.org/keywords/liver-fibrosis","display_name":"liver fibrosis","score":0.8100000023841858},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.734000027179718},{"id":"https://openalex.org/keywords/lipid-metabolism","display_name":"lipid metabolism","score":0.5590000152587891},{"id":"https://openalex.org/keywords/energy-expenditure","display_name":"energy expenditure","score":0.49799999594688416}],"concepts":[{"id":"https://openalex.org/C2776175330","wikidata":"https://www.wikidata.org/wiki/Q1365091","display_name":"Steatosis","level":2,"score":0.8184455037117004},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5781083703041077},{"id":"https://openalex.org/C2908578062","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Liver steatosis","level":4,"score":0.5222928524017334},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.4941692650318146},{"id":"https://openalex.org/C3175096","wikidata":"https://www.wikidata.org/wiki/Q2640417","display_name":"ALDH2","level":4,"score":0.46146610379219055},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4573289155960083},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3752898573875427},{"id":"https://openalex.org/C2778772119","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Fatty liver","level":3,"score":0.36918050050735474},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3482203483581543},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.17761772871017456},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.06963878870010376},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0368804931640625},{"id":"https://openalex.org/C25747580","wikidata":"https://www.wikidata.org/wiki/Q423792","display_name":"Aldehyde dehydrogenase","level":3,"score":0.0},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0016-5085(19)39279-0","doi":"https://doi.org/10.1016/s0016-5085(19)39279-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0016-5085(19)39279-0","pdf_url":null,"source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2944075113","https://openalex.org/W2588296715","https://openalex.org/W6963055474","https://openalex.org/W2946113950","https://openalex.org/W4318336347","https://openalex.org/W2605935026","https://openalex.org/W6944189650","https://openalex.org/W2321981337","https://openalex.org/W2896736088","https://openalex.org/W2335824059"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2019-05-16T00:00:00"}