{"id":"https://openalex.org/W2944651215","doi":"https://doi.org/10.1016/j.jaut.2019.04.010","title":"Interleukin-1\u03b2-induced IRAK1 ubiquitination is required for TH-GM-CSF cell differentiation in T cell-mediated inflammation","display_name":"Interleukin-1\u03b2-induced IRAK1 ubiquitination is required for TH-GM-CSF cell differentiation in T cell-mediated inflammation","publication_year":2019,"publication_date":"2019-05-09","ids":{"openalex":"https://openalex.org/W2944651215","doi":"https://doi.org/10.1016/j.jaut.2019.04.010","mag":"2944651215","pmid":"https://pubmed.ncbi.nlm.nih.gov/31080014"},"language":"en","primary_location":{"id":"doi:10.1016/j.jaut.2019.04.010","doi":"https://doi.org/10.1016/j.jaut.2019.04.010","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jaut.2019.04.010","pdf_url":null,"source":{"id":"https://openalex.org/S187826688","display_name":"Journal of Autoimmunity","issn_l":"0896-8411","issn":["0896-8411","1095-9157"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Autoimmunity","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109297288","display_name":"Yuan Hu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I51185872","display_name":"Jining Medical University","ror":"https://ror.org/03zn9gq54","country_code":"CN","type":"education","lineage":["https://openalex.org/I51185872"]},{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Yuan Hu","raw_affiliation_strings":["Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA; Institute of Immunology and Molecular Medicine, Jining Medical University, Shandong, 272067, China","Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA","Institute of Immunology and Molecular Medicine, Jining Medical University, Shandong, 272067, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA; Institute of Immunology and Molecular Medicine, Jining Medical University, Shandong, 272067, China","institution_ids":["https://openalex.org/I51185872","https://openalex.org/I98704320"]},{"raw_affiliation_string":"Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Institute of Immunology and Molecular Medicine, Jining Medical University, Shandong, 272067, China","institution_ids":["https://openalex.org/I51185872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030472512","display_name":"Feihong Xu","orcid":"https://orcid.org/0000-0002-4120-1146","observed_orcids":["https://orcid.org/0000-0002-4120-1146"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Feihong Xu","raw_affiliation_strings":["Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100703960","display_name":"Ruihua Zhang","orcid":"https://orcid.org/0000-0002-8672-9673","observed_orcids":["https://orcid.org/0000-0002-8672-9673"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ruihua Zhang","raw_affiliation_strings":["Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077100007","display_name":"Diana Legarda","orcid":"https://orcid.org/0000-0003-3177-129X","observed_orcids":["https://orcid.org/0000-0003-3177-129X"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Diana Legarda","raw_affiliation_strings":["Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027047821","display_name":"Jun Dai","orcid":"https://orcid.org/0000-0002-8951-9030","observed_orcids":["https://orcid.org/0000-0002-8951-9030"]},"institutions":[{"id":"https://openalex.org/I51185872","display_name":"Jining Medical University","ror":"https://ror.org/03zn9gq54","country_code":"CN","type":"education","lineage":["https://openalex.org/I51185872"]},{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Jun Dai","raw_affiliation_strings":["Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA; Institute of Immunology and Molecular Medicine, Jining Medical University, Shandong, 272067, China","Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA","Institute of Immunology and Molecular Medicine, Jining Medical University, Shandong, 272067, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA; Institute of Immunology and Molecular Medicine, Jining Medical University, Shandong, 272067, China","institution_ids":["https://openalex.org/I51185872","https://openalex.org/I98704320"]},{"raw_affiliation_string":"Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Institute of Immunology and Molecular Medicine, Jining Medical University, Shandong, 272067, China","institution_ids":["https://openalex.org/I51185872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100401390","display_name":"Di Wang","orcid":"https://orcid.org/0000-0001-8059-9479","observed_orcids":["https://orcid.org/0000-0001-8059-9479"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Di Wang","raw_affiliation_strings":["Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Heyu Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Heyu Li","raw_affiliation_strings":["Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100446958","display_name":"Yao Zhang","orcid":"https://orcid.org/0000-0002-0776-1764","observed_orcids":["https://orcid.org/0000-0002-0776-1764"]},"institutions":[{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yao Zhang","raw_affiliation_strings":["Department of Biological Sciences, Virginia Tech, Blacksburg, VA, 24061, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Virginia Tech, Blacksburg, VA, 24061, USA","institution_ids":["https://openalex.org/I859038795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101848420","display_name":"Qingjie Xue","orcid":"https://orcid.org/0000-0001-5561-4091","observed_orcids":["https://orcid.org/0000-0001-5561-4091"]},"institutions":[{"id":"https://openalex.org/I51185872","display_name":"Jining Medical University","ror":"https://ror.org/03zn9gq54","country_code":"CN","type":"education","lineage":["https://openalex.org/I51185872"]},{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Qingjie Xue","raw_affiliation_strings":["Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA; Institute of Immunology and Molecular Medicine, Jining Medical University, Shandong, 272067, China","Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA","Institute of Immunology and Molecular Medicine, Jining Medical University, Shandong, 272067, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA; Institute of Immunology and Molecular Medicine, Jining Medical University, Shandong, 272067, China","institution_ids":["https://openalex.org/I51185872","https://openalex.org/I98704320"]},{"raw_affiliation_string":"Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Institute of Immunology and Molecular Medicine, Jining Medical University, Shandong, 272067, China","institution_ids":["https://openalex.org/I51185872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025447700","display_name":"Guanjun Dong","orcid":"https://orcid.org/0000-0001-6185-1771","observed_orcids":["https://orcid.org/0000-0001-6185-1771"]},"institutions":[{"id":"https://openalex.org/I51185872","display_name":"Jining Medical University","ror":"https://ror.org/03zn9gq54","country_code":"CN","type":"education","lineage":["https://openalex.org/I51185872"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guanjun Dong","raw_affiliation_strings":["Institute of Immunology and Molecular Medicine, Jining Medical University, Shandong, 272067, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Immunology and Molecular Medicine, Jining Medical University, Shandong, 272067, China","institution_ids":["https://openalex.org/I51185872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100323555","display_name":"Hui Zhang","orcid":"https://orcid.org/0000-0003-3620-610X","observed_orcids":["https://orcid.org/0000-0003-3620-610X","https://orcid.org/0000-0002-5232-0335","https://orcid.org/0000-0002-5693-5222"]},"institutions":[{"id":"https://openalex.org/I51185872","display_name":"Jining Medical University","ror":"https://ror.org/03zn9gq54","country_code":"CN","type":"education","lineage":["https://openalex.org/I51185872"]},{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Hui Zhang","raw_affiliation_strings":["Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA; Institute of Immunology and Molecular Medicine, Jining Medical University, Shandong, 272067, China","Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA","Institute of Immunology and Molecular Medicine, Jining Medical University, Shandong, 272067, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA; Institute of Immunology and Molecular Medicine, Jining Medical University, Shandong, 272067, China","institution_ids":["https://openalex.org/I51185872","https://openalex.org/I98704320"]},{"raw_affiliation_string":"Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Institute of Immunology and Molecular Medicine, Jining Medical University, Shandong, 272067, China","institution_ids":["https://openalex.org/I51185872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100702058","display_name":"Chang Lu","orcid":"https://orcid.org/0000-0003-0181-5888","observed_orcids":["https://orcid.org/0000-0003-0181-5888","https://orcid.org/0009-0008-6682-368X","https://orcid.org/0009-0004-7506-7944"]},"institutions":[{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chang Lu","raw_affiliation_strings":["Department of Biomedical Engineering, Virginia Tech, Blacksburg, VA, 24061, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Virginia Tech, Blacksburg, VA, 24061, USA","institution_ids":["https://openalex.org/I859038795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040852112","display_name":"Arthur Mortha","orcid":"https://orcid.org/0000-0003-2673-0485","observed_orcids":["https://orcid.org/0000-0003-2673-0485"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Arthur Mortha","raw_affiliation_strings":["Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100333043","display_name":"Jianguo Liu","orcid":"https://orcid.org/0000-0002-0997-5838","observed_orcids":["https://orcid.org/0000-0002-0997-5838"]},"institutions":[{"id":"https://openalex.org/I47838141","display_name":"Saint Louis University","ror":"https://ror.org/01p7jjy08","country_code":"US","type":"education","lineage":["https://openalex.org/I47838141"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jianguo Liu","raw_affiliation_strings":["Departments of Internal Medicine & Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, MO, 63104, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Internal Medicine & Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, MO, 63104, USA","institution_ids":["https://openalex.org/I47838141"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005075162","display_name":"Paolo Cravedi","orcid":"https://orcid.org/0000-0001-7837-0923","observed_orcids":["https://orcid.org/0000-0001-7837-0923"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paolo Cravedi","raw_affiliation_strings":["Department of Medicine, Translational Transplant Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Translational Transplant Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019205026","display_name":"Adrian T. Ting","orcid":"https://orcid.org/0000-0003-0653-9923","observed_orcids":["https://orcid.org/0000-0003-0653-9923"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adrian Ting","raw_affiliation_strings":["Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100455242","display_name":"Liwu Li","orcid":"https://orcid.org/0000-0001-8870-5299","observed_orcids":["https://orcid.org/0000-0001-8870-5299"]},"institutions":[{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Liwu Li","raw_affiliation_strings":["Department of Biological Sciences, Virginia Tech, Blacksburg, VA, 24061, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Virginia Tech, Blacksburg, VA, 24061, USA","institution_ids":["https://openalex.org/I859038795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052612176","display_name":"Chen\u2010Feng Qi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chen-feng Qi","raw_affiliation_strings":["Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025853358","display_name":"Susan K. Pierce","orcid":"https://orcid.org/0000-0001-7261-3437","observed_orcids":["https://orcid.org/0000-0001-7261-3437","https://orcid.org/0000-0002-1484-7566"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan Pierce","raw_affiliation_strings":["Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070354041","display_name":"Miriam M\u00e9rad","orcid":"https://orcid.org/0000-0002-4481-7827","observed_orcids":["https://orcid.org/0000-0002-4481-7827"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Miriam Merad","raw_affiliation_strings":["Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088980123","display_name":"Peter S. Heeger","orcid":"https://orcid.org/0000-0003-4673-6913","observed_orcids":["https://orcid.org/0000-0003-4673-6913"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Peter Heeger","raw_affiliation_strings":["Department of Medicine, Translational Transplant Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. Electronic address: peter.heeger@mssm.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Translational Transplant Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. Electronic address: peter.heeger@mssm.edu","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028065092","display_name":"Huabao Xiong","orcid":"https://orcid.org/0000-0003-0180-2104","observed_orcids":["https://orcid.org/0000-0003-0180-2104"]},"institutions":[{"id":"https://openalex.org/I51185872","display_name":"Jining Medical University","ror":"https://ror.org/03zn9gq54","country_code":"CN","type":"education","lineage":["https://openalex.org/I51185872"]},{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["CN","US"],"is_corresponding":true,"raw_author_name":"Huabao Xiong","raw_affiliation_strings":["Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA; Institute of Immunology and Molecular Medicine, Jining Medical University, Shandong, 272067, China. Electronic address: Huabao.Xiong@mssm.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA; Institute of Immunology and Molecular Medicine, Jining Medical University, Shandong, 272067, China. Electronic address: Huabao.Xiong@mssm.edu","institution_ids":["https://openalex.org/I51185872","https://openalex.org/I98704320"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5028065092","https://openalex.org/A5088980123"],"corresponding_institution_ids":["https://openalex.org/I51185872","https://openalex.org/I98704320"],"apc_list":{"value":4250,"currency":"USD","value_usd":4250},"apc_paid":null,"fwci":0.8973,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.69885855,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"102","issue":null,"first_page":"50","last_page":"64"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.7250999808311462,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.7250999808311462,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis","score":0.2524000108242035,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11591","display_name":"NF-\u03baB Signaling Pathways","score":0.007699999958276749,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interleukin-1beta","display_name":"IL-1\u03b2","score":0.9290000200271606},{"id":"https://openalex.org/keywords/cd4-t-cell-differentiation","display_name":"CD4+ T cell differentiation","score":0.8410000205039978},{"id":"https://openalex.org/keywords/nf-kappab-signaling","display_name":"NF-\u03baB signaling","score":0.8429999947547913},{"id":"https://openalex.org/keywords/rorgammat","display_name":"ROR\u03b3t","score":0.8610000014305115},{"id":"https://openalex.org/keywords/t-helper-cell-subsets","display_name":"T helper cell subsets","score":0.7599999904632568},{"id":"https://openalex.org/keywords/macrophage-activation","display_name":"macrophage activation","score":0.8790000081062317},{"id":"https://openalex.org/keywords/colitis","display_name":"colitis","score":0.8069999814033508},{"id":"https://openalex.org/keywords/citrobacter-rodentium-infection","display_name":"Citrobacter rodentium infection","score":0.9620000123977661},{"id":"https://openalex.org/keywords/t-cell-mediated-inflammation","display_name":"T cell-mediated inflammation","score":0.8199999928474426},{"id":"https://openalex.org/keywords/il-17","display_name":"IL-17","score":0.7710000276565552}],"concepts":[{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.6912364959716797},{"id":"https://openalex.org/C25602115","wikidata":"https://www.wikidata.org/wiki/Q407111","display_name":"Ubiquitin","level":3,"score":0.6174792647361755},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5806913375854492},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.38831013441085815},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.341444194316864},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.30556175112724304},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.18317186832427979},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.15565225481987}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003092","descriptor_name":"Colitis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008262","descriptor_name":"Macrophage Activation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016178","descriptor_name":"Granulocyte-Macrophage Colony-Stimulating Factor","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D016328","descriptor_name":"NF-kappa B","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044082","descriptor_name":"Citrobacter rodentium","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053583","descriptor_name":"Interleukin-1beta","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D053592","descriptor_name":"Interleukin-1 Receptor-Associated Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D054875","descriptor_name":"Ubiquitination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057132","descriptor_name":"Nuclear Receptor Subfamily 1, Group F, Member 3","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D058504","descriptor_name":"Th17 Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D058504","descriptor_name":"Th17 Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D058504","descriptor_name":"Th17 Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jaut.2019.04.010","doi":"https://doi.org/10.1016/j.jaut.2019.04.010","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jaut.2019.04.010","pdf_url":null,"source":{"id":"https://openalex.org/S187826688","display_name":"Journal of Autoimmunity","issn_l":"0896-8411","issn":["0896-8411","1095-9157"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Autoimmunity","raw_type":"journal-article"},{"id":"pmid:31080014","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31080014","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of autoimmunity","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2225722384","display_name":"T cell-derived iNOS switches off TH17 cell differentiation in inflammation","funder_award_id":"R01AI104688","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G5188724650","display_name":"Cell Death Pathways and Heart Transplant Rejection","funder_award_id":"R01AI132405","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G7377485848","display_name":"Complement & T Cell Medicated Allograft Rejection","funder_award_id":"R01AI071185","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320309658","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W1535842809","https://openalex.org/W1568406709","https://openalex.org/W1691245493","https://openalex.org/W1816536644","https://openalex.org/W1829500673","https://openalex.org/W1861089293","https://openalex.org/W1890836614","https://openalex.org/W1950482131","https://openalex.org/W1966226308","https://openalex.org/W1967369695","https://openalex.org/W1970195004","https://openalex.org/W1979292513","https://openalex.org/W1993003564","https://openalex.org/W1994107743","https://openalex.org/W1998895238","https://openalex.org/W2006249161","https://openalex.org/W2009265290","https://openalex.org/W2011882192","https://openalex.org/W2017893786","https://openalex.org/W2021340905","https://openalex.org/W2043897997","https://openalex.org/W2063680739","https://openalex.org/W2067401763","https://openalex.org/W2069571875","https://openalex.org/W2084388036","https://openalex.org/W2086968599","https://openalex.org/W2090069133","https://openalex.org/W2112065614","https://openalex.org/W2112785503","https://openalex.org/W2122084527","https://openalex.org/W2126185185","https://openalex.org/W2127245407","https://openalex.org/W2127642399","https://openalex.org/W2133010278","https://openalex.org/W2140380746","https://openalex.org/W2142017607","https://openalex.org/W2144288685","https://openalex.org/W2145164170","https://openalex.org/W2145385239","https://openalex.org/W2157837362","https://openalex.org/W2168436315","https://openalex.org/W2271015490","https://openalex.org/W2284327277","https://openalex.org/W2531186684","https://openalex.org/W2556561046","https://openalex.org/W2557462117","https://openalex.org/W4248219898"],"related_works":["https://openalex.org/W3165494731","https://openalex.org/W2890108093","https://openalex.org/W2003057093","https://openalex.org/W2133010278","https://openalex.org/W2567177563","https://openalex.org/W2145385239","https://openalex.org/W2055814218","https://openalex.org/W32203441","https://openalex.org/W4404773553","https://openalex.org/W2139239408"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-05-16T00:00:00"}